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3. SOCIAL SKILLS INTERVENTIONS FOR ADOLESCENTS WITH LEVEL 1 AUTISM SPECTRUM DISORDER: A SYSTEMATIC REVIEW WITH META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.

Author

Narzisi, Antonio, Sesso, Gianluca, Fabbri-Destro, Maddalena, Berloffa, Stefano, Fantozzi, Pamela, Muccio, Rosy, Bruzzi, Gianina, Scatigna, Stefano, Valente, Elena, Viglione, Valentina, Milone, Annarita, Cortese, Samuele, and Masi, Gabriele

Subjects
SOCIAL skills education, AUTISM spectrum disorders, RANDOMIZED controlled trials, SOCIAL skills, INVESTIGATIONAL therapies
Abstract

Objective: Evidence on the efficacy of social skills training for adolescents with Level 1 Autism Spectrum Disorder (ASD) is unclear. Method: We searched Pubmed, Scopus, and Web of Science until July 27th, 2023, for randomized controlled trials (RCTs) of social skills training for pre-adolescents and adolescents (aged 9-18) with Level 1 ASD. We then pooled data on efficacy from individual RCTs by conducting multivariate mixed-effects meta-analyses in R. We estimated possible bias in the retained RCTs using the RoB2 tool. Results: We retained 36 RCTs (encompassing 2796 participants), including 18 RCTs comparing an experimental treatment to a waiting list, and 18 RCTs comparing it to standard care/control treatment. Meta-analyses showed that experimental treatments were significantly more efficacious than waiting list or standard care/ control treatments in improving social skills (SMD = 0.3745; 95%CI = [0.2396; 0.5093]), as well as reducing behavioral symptoms (0.3154;0.1783, 0.4525) and anxious/depressive symptoms (0.2780; 0.0432, 0.5128). However, for some outcomes there was significant heterogeneity across studies and evidence of publication bias. Subgroup analyses and meta-regressions did not identify any specific clinical or demographic factors as significant predictors of outcome. The most common risk of bias across studies was related to deviations from intended interventions and measurement of the outcomes. Conclusions: At the group level, social skills training for adolescents with Level 1 ASD is efficacious, with small-to-moderate effect size. Future research should focus on personalized medicine approaches, aimed at tailoring interventions to specific characteristics of adolescents with Level 1 ASD. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Learning climate and quality of Italian training courses in gynecology and obstetrics

Author

Candiani, Massimo, Casarin, Jvan, Ciavattini, Andrea, Paola, Rossana Di, Greco, Pantaleo, Guaschino, Secondo, Marchesoni, Diego, Milani, Rodolfo, Rizzo, Nicola, Venturini, Pier Luigi, Valente, Elena, Vizza, Enrico, Zanconato, Giovanni, Zullo, Fulvio, Sartori, Enrico, Ghezzi, Fabio, Cromi, Antonella, Laganà, Antonio Simone, Garzon, Simone, Raffaelli, Ricciarda, Scambia, Giovanni, and Franchi, Massimo

Published
2019
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9. Reduced prevalence of fetal exposure to alcohol in Italy: a nationwide survey

Author

La Maida, Nunzia, primary, Di Giorgi, Alessandro, additional, Pellegrini, Manuela, additional, Ceccanti, Mauro, additional, Caruso, Salvatore, additional, Ricci, Giuseppe, additional, Neri, Isabella, additional, Lana, Sheherazade, additional, Minutillo, Adele, additional, Berretta, Paolo, additional, Busardò, Francesco Paolo, additional, Pichini, Simona, additional, Camandona, Franco, additional, Vaccari, Lucia, additional, Travan, Laura, additional, Maso, Giampaolo, additional, Stampalija, Tamara, additional, Zanazzo, Lucia, additional, Pisana, Paola, additional, Driul, Lorenza, additional, Barbui, Elisa, additional, Caissutti, Claudia, additional, Valente, Elena, additional, Ricchi, Alba, additional, Bettiga, Elisa, additional, Piccolo, Elisa, additional, Pati, Mariangela, additional, Pedori, Simona, additional, Antonazzo, Patrizio, additional, Sottile, Gilda, additional, Faro, Fabrizio Lo, additional, Tini, Anastasio, additional, Massacesi, Mario, additional, Rapisarda, Carmen, additional, Vivirito, Gabriella, additional, Pinna, Giampiero, additional, D'anna, Mariarosa, additional, Klein, Lili, additional, Bucolo, Antonino, additional, D'Anna, Rosario, additional, Monaco, Caterina, additional, La Ferrera, Giuseppe, additional, Capobianco, Giampiero, additional, Olzai, Mauro Giorgio, additional, Angioni, Stefano, additional, D'Alterio, Maurizio Nicola, additional, Serravalle, Paolo, additional, Vicquéry, Christine, additional, Scalchi, Sabrina, additional, Morando, Carla, additional, Meneghin, Margherita, additional, Scapolan, Cinzia, additional, Maggino, Tiziano, additional, Guarinoni, Barbara, additional, Napolitano, Giovanna M. Cristina, additional, De Vita, Maria Grazia, additional, Carlo, Costantino Di, additional, Interlandi, Fabiana, additional, Bisceglia, Massimo, additional, Barbaglia, Michelangelo, additional, Arnulfo, Alberto, additional, Finale, Enrico, additional, Marozio, Luca, additional, Natali, Ilaria, additional, Grazia, Signoretti Maria, additional, Staffler, Alex, additional, Tarani, Luigi, additional, Coriale, Giovanna, additional, Messina, Marisa Patrizia, additional, D'Angelo, Alessio, additional, Bonito, Marco, additional, Haass, Cristina, additional, Capasso, Letizia, additional, Raimondi, Francesco, additional, De Bernardo, Giuseppe, additional, Iacobelli, Pietro, additional, Spadarella, Simona, additional, Mastantuoni, Enrica, additional, Rabuano, Raffaello, additional, Calzatini, Francesco, additional, Bossi, Anna, additional, Aversa, Salvatore, additional, Prefumo, Federico, additional, Bellan, Cristina, additional, Leone, Giovanna, additional, Ciammella, Massimo, additional, Von-Wunster, Silvia, additional, Liguori, Antonella, additional, Ornaghi, Sara, additional, Fumagalli, Simona, additional, Sanguineti, Fabio, additional, Gianola, Gaia, additional, Cagnacci, Angelo, additional, Amidani, Arianna, additional, Sisto, Antonio, additional, Marcello, Francesca Di, additional, Santillo, Vincenzo, additional, Bartolomeo, Cristina Di, additional, Gerli, Sandro, additional, Cagnoli, Giacomo, additional, Petrisano, Mirella, additional, Pesce, Simona, additional, Lascio, Nicola Di, additional, Falvino, Sonia, additional, Appio, Petronilla, additional, Targiani, Vincenza, additional, Cavaliere, Anna Franca, additional, Turrini, Irene, additional, Belli, Gilda, additional, Gambi, Beatrice, additional, Florio, Pasquale, additional, Innocenti, Elena Degli, additional, Magi, Letizia, additional, Civitelli, Flavio, additional, Nappi, Luigi, additional, Sorrentino, Felice, additional, Silvestris, Teresa, additional, Indrio, Flavia, additional, Laforgia, Nicola, additional, Rizzo, Valentina, additional, La Rocca, Maria, additional, Pradal, Ugo, additional, Memo, Luigi, additional, Diaz, Claudio, additional, Riscica, Patrizia, additional, and Bazz, Stefania, additional

Published
2023
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10. Persistent Non-Suicidal Self-Injury and Suicidality in Referred Adolescents: A Longitudinal Study Exploring the Role of Cyclothymic Temperament

Author

Masi, Gabriele, primary, Pisano, Simone, additional, Sesso, Gianluca, additional, Mazzullo, Cristina, additional, Berloffa, Stefano, additional, Fantozzi, Pamela, additional, Narzisi, Antonio, additional, Placini, Francesca, additional, Valente, Elena, additional, Viglione, Valentina, additional, and Milone, Annarita, additional

Published
2023
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11. Micromolar Dihydroartemisinin Concentrations Elicit Lipoperoxidation in Plasmodium falciparum -Infected Erythrocytes.

Author

Skorokhod, Oleksii, Valente, Elena, Mandili, Giorgia, Ulliers, Daniela, and Schwarzer, Evelin

Subjects
PLASMODIUM falciparum, ERYTHROCYTES, PARASITIC diseases, LIPIDS, REACTIVE oxygen species, ARTEMISININ
Abstract

Malaria is still the most important parasitic infectious disease. Numerous substances are known to have antimalarial activity; among them, artemisinin is the most widely used one, and artemisinin-based combination therapy (ACT) is recommended for the treatment of Plasmodium falciparum (P.f.) malaria. Antitumor, immunomodulatory, and other therapeutic applications of artemisinin are under extensive study. Several different mechanisms of action were proposed for dihydroartemisinin (DHA), the active metabolite of artemisinin, such as eliciting oxidative stress in target cells. The goal of this study is to monitor the generation of reactive oxygen species (ROS) and lipid peroxidation product 4-hydroxynonenal (4-HNE) by DHA in P.f.-infected human erythrocytes. Checking ROS and 4-HNE-protein adducts kinetics along the maturation of the parasite, we detected the highest level of 4-HNE in ring forms of P.f. due to DHA treatment. Low micromolar concentrations of DHA quickly induced levels of 4-HNE-adducts which are supposed to be damaging. Mass spectrometry identified the P.f. protein cysteine proteinase falcipain-1 as being heavily modified by 4-HNE, and plausibly, 4-HNE conjugation with vital P.f. proteins might contribute to DHA-elicited parasite death. In conclusion, significant 4-HNE accumulation was detectable after DHA treatment, though, at concentrations well above pharmacologically effective ranges in malaria treatment, but at concentrations described for antitumor activity. Thus, lipid peroxidation with consequent 4-HNE conjugation of functionally relevant proteins might be considered as a uniform mechanism for how DHA potentiates antimalarials' action in ACT and controls the progression of tumors. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Reduced prevalence of fetal exposure to alcohol in Italy: a nationwide survey

Author

Camandona, Franco, Vaccari, Lucia, Travan, Laura, Maso, Giampaolo, Stampalija, Tamara, Zanazzo, Lucia, Pisana, Paola, Driul, Lorenza, Barbui, Elisa, Caissutti, Claudia, Valente, Elena, Ricchi, Alba, Bettiga, Elisa, Piccolo, Elisa, Pati, Mariangela, Pedori, Simona, Antonazzo, Patrizio, Sottile, Gilda, Faro, Fabrizio Lo, Tini, Anastasio, Massacesi, Mario, Rapisarda, Carmen, Vivirito, Gabriella, Pinna, Giampiero, D'anna, Mariarosa, Klein, Lili, Bucolo, Antonino, D'Anna, Rosario, Monaco, Caterina, La Ferrera, Giuseppe, Capobianco, Giampiero, Olzai, Mauro Giorgio, Angioni, Stefano, D'Alterio, Maurizio Nicola, Serravalle, Paolo, Vicquéry, Christine, Scalchi, Sabrina, Morando, Carla, Meneghin, Margherita, Scapolan, Cinzia, Maggino, Tiziano, Guarinoni, Barbara, Napolitano, Giovanna M. Cristina, De Vita, Maria Grazia, Carlo, Costantino Di, Interlandi, Fabiana, Bisceglia, Massimo, Barbaglia, Michelangelo, Arnulfo, Alberto, Finale, Enrico, Marozio, Luca, Natali, Ilaria, Grazia, Signoretti Maria, Staffler, Alex, Tarani, Luigi, Coriale, Giovanna, Messina, Marisa Patrizia, D'Angelo, Alessio, Bonito, Marco, Haass, Cristina, Capasso, Letizia, Raimondi, Francesco, De Bernardo, Giuseppe, Iacobelli, Pietro, Spadarella, Simona, Mastantuoni, Enrica, Rabuano, Raffaello, Calzatini, Francesco, Bossi, Anna, Aversa, Salvatore, Prefumo, Federico, Bellan, Cristina, Leone, Giovanna, Ciammella, Massimo, Von-Wunster, Silvia, Liguori, Antonella, Ornaghi, Sara, Fumagalli, Simona, Sanguineti, Fabio, Gianola, Gaia, Cagnacci, Angelo, Amidani, Arianna, Sisto, Antonio, Marcello, Francesca Di, Santillo, Vincenzo, Bartolomeo, Cristina Di, Gerli, Sandro, Cagnoli, Giacomo, Petrisano, Mirella, Pesce, Simona, Lascio, Nicola Di, Falvino, Sonia, Appio, Petronilla, Targiani, Vincenza, Cavaliere, Anna Franca, Turrini, Irene, Belli, Gilda, Gambi, Beatrice, Florio, Pasquale, Innocenti, Elena Degli, Magi, Letizia, Civitelli, Flavio, Nappi, Luigi, Sorrentino, Felice, Silvestris, Teresa, Indrio, Flavia, Laforgia, Nicola, Rizzo, Valentina, La Rocca, Maria, Pradal, Ugo, Memo, Luigi, Diaz, Claudio, Riscica, Patrizia, Bazz, Stefania, La Maida, Nunzia, Di Giorgi, Alessandro, Pellegrini, Manuela, Ceccanti, Mauro, Caruso, Salvatore, Ricci, Giuseppe, Neri, Isabella, Lana, Sheherazade, Minutillo, Adele, Berretta, Paolo, Busardò, Francesco Paolo, and Pichini, Simona

Published
2023
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14. Early Sensory Profile in Autism Spectrum Disorders Predicts Emotional and Behavioral Issues

Author

Fabbri-Destro, Maddalena, primary, Maugeri, Federica, additional, Ianni, Carolina, additional, Corsini, Sofia, additional, Di Stefano, Erica, additional, Scatigna, Stefano, additional, Crifaci, Giulia, additional, Bruzzi, Gianina, additional, Berloffa, Stefano, additional, Fantozzi, Pamela, additional, Prato, Adriana, additional, Muccio, Rosy, additional, Valente, Elena, additional, Pelagatti, Susanna, additional, Pecchini, Edoardo, additional, Zulli, Filippo, additional, Rizzo, Renata, additional, Milone, Annarita, additional, Viglione, Valentina, additional, Barone, Rita, additional, Masi, Gabriele, additional, and Narzisi, Antonio, additional

Published
2022
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15. An Optimized Dihydrodibenzothiazepine Lead Compound (SBI-0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6-Phosphate Dehydrogenase 6-Phosphogluconolactonase

Author

Berneburg, Isabell, primary, Peddibhotla, Satyamaheshwar, additional, Heimsch, Kim C., additional, Haeussler, Kristina, additional, Maloney, Patrick, additional, Gosalia, Palak, additional, Preuss, Janina, additional, Rahbari, Mahsa, additional, Skorokhod, Oleksii, additional, Valente, Elena, additional, Ulliers, Daniela, additional, Simula, Luigi Felice, additional, Buchholz, Kathrin, additional, Hedrick, Michael P., additional, Hershberger, Paul, additional, Chung, Thomas D. Y., additional, Jackson, Michael R., additional, Schwarzer, Evelin, additional, Rahlfs, Stefan, additional, Bode, Lars, additional, Becker, Katja, additional, and Pinkerton, Anthony B., additional

Published
2022
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16. Sensory Profiles in School-Aged Children with Autism Spectrum Disorder: A Descriptive Study Using the Sensory Processing Measure-2 (SPM-2)

Author

Narzisi, Antonio, primary, Fabbri-Destro, Maddalena, additional, Crifaci, Giulia, additional, Scatigna, Stefano, additional, Maugeri, Federica, additional, Berloffa, Stefano, additional, Fantozzi, Pamela, additional, Prato, Adriana, additional, Muccio, Rosy, additional, Valente, Elena, additional, Viglione, Valentina, additional, Pecchini, Edoardo, additional, Pelagatti, Susanna, additional, Rizzo, Renata, additional, Milone, Annarita, additional, Barone, Rita, additional, and Masi, Gabriele, additional

Published
2022
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19. A novel multidimensional questionnaire for the assessment of emotional dysregulation in adolescents: Reactivity, Intensity, Polarity and Stability questionnaire–youth version (RIPoSt–Y)

Author

Sesso, Gianluca, primary, Milone, Annarita, additional, Drago, Flavia, additional, Viglione, Valentina, additional, Berloffa, Stefano, additional, Boldrini, Silvia, additional, Loriaux, Nina, additional, Valente, Elena, additional, Molesti, Agnese, additional, Placini, Francesca, additional, Montesanto, Anna Rita, additional, Pisano, Simone, additional, and Masi, Gabriele, additional

Published
2021
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20. Could You Give Me the Blue Brick? LEGO®-Based Therapy as a Social Development Program for Children with Autism Spectrum Disorder: A Systematic Review

Author

Narzisi, Antonio, primary, Sesso, Gianluca, additional, Berloffa, Stefano, additional, Fantozzi, Pamela, additional, Muccio, Rosy, additional, Valente, Elena, additional, Viglione, Valentina, additional, Villafranca, Arianna, additional, Milone, Annarita, additional, and Masi, Gabriele, additional

Published
2021
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21. An Exploratory Study of Emotional Dysregulation Dimensions in Youth With Attention Deficit Hyperactivity Disorder and/or Bipolar Spectrum Disorders

Author

Masi, Gabriele, primary, Sesso, Gianluca, additional, Pfanner, Chiara, additional, Valente, Elena, additional, Molesti, Agnese, additional, Placini, Francesca, additional, Boldrini, Silvia, additional, Loriaux, Nina, additional, Drago, Flavia, additional, Montesanto, Anna Rita, additional, Pisano, Simone, additional, and Milone, Annarita, additional

Published
2021
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23. Reactivity, Intensity, Polarity and Stability Questionnaire--Youth Version

Author

Sesso, Gianluca, primary, Milone, Annarita, additional, Drago, Flavia, additional, Viglione, Valentina, additional, Berloffa, Stefano, additional, Boldrini, Silvia, additional, Loriaux, Nina, additional, Valente, Elena, additional, Molesti, Agnese, additional, Placini, Francesca, additional, Montesanto, Anna Rita, additional, Pisano, Simone, additional, and Masi, Gabriele, additional

Published
2021
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24. Autism Spectrum Disorder and Disruptive Behavior Disorders Comorbidities Delineate Clinical Phenotypes in Attention-Deficit Hyperactivity Disorder: Novel Insights from the Assessment of Psychopathological and Neuropsychological Profiles

Author

Sesso, Gianluca, primary, Cristofani, Chiara, additional, Berloffa, Stefano, additional, Cristofani, Paola, additional, Fantozzi, Pamela, additional, Inguaggiato, Emanuela, additional, Narzisi, Antonio, additional, Pfanner, Chiara, additional, Ricci, Federica, additional, Tacchi, Annalisa, additional, Valente, Elena, additional, Viglione, Valentina, additional, Milone, Annarita, additional, and Masi, Gabriele, additional

Published
2020
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25. The Role of Executive Functions in the Development of Empathy and Its Association with Externalizing Behaviors in Children with Neurodevelopmental Disorders and Other Psychiatric Comorbidities

Author

Cristofani, Chiara, primary, Sesso, Gianluca, additional, Cristofani, Paola, additional, Fantozzi, Pamela, additional, Inguaggiato, Emanuela, additional, Muratori, Pietro, additional, Narzisi, Antonio, additional, Pfanner, Chiara, additional, Pisano, Simone, additional, Polidori, Lisa, additional, Ruglioni, Laura, additional, Valente, Elena, additional, Masi, Gabriele, additional, and Milone, Annarita, additional

Published
2020
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28. Learning climate and quality of Italian training courses in gynecology and obstetrics

Author

Sartori, Enrico, primary, Ghezzi, Fabio, additional, Cromi, Antonella, additional, Laganà, Antonio Simone, additional, Garzon, Simone, additional, Raffaelli, Ricciarda, additional, Scambia, Giovanni, additional, Franchi, Massimo, additional, Candiani, Massimo, additional, Casarin, Jvan, additional, Ciavattini, Andrea, additional, Paola, Rossana Di, additional, Greco, Pantaleo, additional, Guaschino, Secondo, additional, Marchesoni, Diego, additional, Milani, Rodolfo, additional, Rizzo, Nicola, additional, Venturini, Pier Luigi, additional, Valente, Elena, additional, Vizza, Enrico, additional, Zanconato, Giovanni, additional, and Zullo, Fulvio, additional

Published
2019
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29. La producción de escritos en postgrados internacionales: La incidencia de las tradiciones académicas en la apropiación y producción de saberes

Author

Nothstein,Susana B and Valente,Elena A

Subjects
Nivel de postgrado, tradiciones académicas, apropiación y producción de saberes, escritura
Abstract

En el artículo se estudian monografías elaboradas en el marco de talleres de escritura académica para espacios curriculares iniciales de especializaciones y maestrías interdisciplinarias e internacionales en el área de las Ciencias Sociales y Humanas, radicadas en la ciudad de Buenos Aires. Se analiza, con una metodología predominantemente cualitativa, si esos escritos se corresponden con el género que los estudiantes deben producir. El propósito del trabajo es, en primer lugar, determinar si las tradiciones académicas en las que se inscriben los alumnos inciden en las aproximaciones o los distanciamientos de los rasgos del género monografía que se verifican en sus escritos. Para ello, el análisis del corpus se confronta con los resultados de una encuesta aplicada a los mismos sujetos. En segundo lugar, el trabajo busca identificar dificultades propias del ámbito en el que los estudiantes se incorporan, sobre todo, respecto de la apropiación y producción de saberes. Para alcanzar tales objetivos, se analiza un corpus conformado por sesenta monografías, treinta de estudiantes argentinos y treinta de estudiantes extranjeros.

Published
2016

30. La producción de escritos en postgrados internacionales: La incidencia de las tradiciones académicas en la apropiación y producción de saberes

Author

Nothstein, Susana B and Valente, Elena A

Subjects
Nivel de postgrado, tradiciones académicas, apropiación y producción de saberes, Postgraduate level, appropriation and production of knowledge, escritura, academic traditions, writing
Abstract

En el artículo se estudian monografías elaboradas en el marco de talleres de escritura académica para espacios curriculares iniciales de especializaciones y maestrías interdisciplinarias e internacionales en el área de las Ciencias Sociales y Humanas, radicadas en la ciudad de Buenos Aires. Se analiza, con una metodología predominantemente cualitativa, si esos escritos se corresponden con el género que los estudiantes deben producir. El propósito del trabajo es, en primer lugar, determinar si las tradiciones académicas en las que se inscriben los alumnos inciden en las aproximaciones o los distanciamientos de los rasgos del género monografía que se verifican en sus escritos. Para ello, el análisis del corpus se confronta con los resultados de una encuesta aplicada a los mismos sujetos. En segundo lugar, el trabajo busca identificar dificultades propias del ámbito en el que los estudiantes se incorporan, sobre todo, respecto de la apropiación y producción de saberes. Para alcanzar tales objetivos, se analiza un corpus conformado por sesenta monografías, treinta de estudiantes argentinos y treinta de estudiantes extranjeros. The article considers monographs written in the framework of academic writing workshops for initial curriculum areas of specialization and for interdisciplinary and international master's degrees in the area of Social and Human Sciences located in Buenos Aires. It analyses, with a predominantly qualitative methodology, whether these writings correspond to the genre that students are required to produce. The purpose of the study is to determine, first, whether academic traditions in which students enroll affect approaches or distances of the features of the genre, which are verified in their monograph writings. To do so, the analysis of the corpus is confronted with the results of an inquiry applied to the same students. Second, the work aims to identify difficulties of graduate level in which students are incorporated, especially with respect to the appropriation and production of knowledge. To achieve these objectives, a corpus composed of sixty monographs, thirty written by Argentine students, and thirty produced by foreign students, is analysed.

Published
2016

34. Oxidative stress-mediated antimalarial activity of plakortin, a natural endoperoxide from the tropical sponge Plakortis simplex

Author

Skorokhod, Oleksii A., primary, Davalos-Schafler, Denise, additional, Gallo, Valentina, additional, Valente, Elena, additional, Ulliers, Daniela, additional, Notarpietro, Agata, additional, Mandili, Giorgia, additional, Novelli, Francesco, additional, Persico, Marco, additional, Taglialatela-Scafati, Orazio, additional, Arese, Paolo, additional, and Schwarzer, Evelin, additional

Published
2015
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37. De la revisión a la reescritura: recorridos de las producciones escritas de estudiantes universitarios.

Author

Pereira, María Cecilia and Valente, Elena

Abstract

Copyright of Revista Góndola, Enseñanza y Aprendizaje de las Ciencias is the property of Gondola, Ensenanza y Aprendizaje de las Ciencias and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2017
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39. Neuropsychological Characterization of Aggressive Behavior in Children and Adolescents with CD/ODD and Effects of Single Doses of Medications: The Protocol of the Matrics_WP6-1 Study.

Author

Balia, Carla, Carucci, Sara, Milone, Annarita, Romaniello, Roberta, Valente, Elena, Donno, Federica, Montesanto, Annarita, Brovedani, Paola, Masi, Gabriele, Glennon, Jeffrey C., Coghill, David, and Zuddas, Alessandro

Subjects
CHILD psychology, AGGRESSION (Psychology), MENTAL health services, DYSAUTONOMIA, CONDUCT disorders in children, HEART beat, DRUGS, CONDUCT disorders in adolescence
Abstract

Aggressive behaviors and disruptive/conduct disorders are some of the commonest reasons for referral to youth mental health services; nevertheless, the efficacy of therapeutic interventions in real-world clinical practice remains unclear. In order to define more appropriate targets for innovative pharmacological therapies for disruptive/conduct disorders, the European Commission within the Seventh Framework Programme (FP7) funded the MATRICS project (Multidisciplinary Approaches to Translational Research in Conduct Syndromes) to identify neural, genetic, and molecular factors underpinning the pathogenesis of aggression/antisocial behavior in preclinical models and clinical samples. Within the program, a multicentre case-control study, followed by a single-blind, placebo-controlled, cross-over, randomized acute single-dose medication challenge, was conducted at two Italian sites. Aggressive children and adolescents with conduct disorder (CD) or oppositional defiant disorder (ODD) were compared to the same age (10–17 y) typically developing controls (TDC) on a neuropsychological tasks battery that included both "cold" (e.g., inhibitory control, decision making) and "hot" executive functions (e.g., moral judgment, emotion processing, risk assessment). Selected autonomic measures (heart rate variability, skin conductance, salivary cortisol) were recorded before/during/after neuropsychological testing sessions. The acute response to different drugs (methylphenidate/atomoxetine, risperidone/aripiprazole, or placebo) was also examined in the ODD/CD cohort in order to identify potential neuropsychological/physiological mechanisms underlying aggression. The paper describes the protocol of the clinical MATRICS WP6-1 study, its rationale, the specific outcome measures, and their implications for a precision medicine approach. [ABSTRACT FROM AUTHOR]

Published
2021
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40. Could You Give Me the Blue Brick? LEGO ® -Based Therapy as a Social Development Program for Children with Autism Spectrum Disorder: A Systematic Review.

Author

Narzisi, Antonio, Sesso, Gianluca, Berloffa, Stefano, Fantozzi, Pamela, Muccio, Rosy, Valente, Elena, Viglione, Valentina, Villafranca, Arianna, Milone, Annarita, and Masi, Gabriele

Subjects
CHILDREN with autism spectrum disorders, SOCIAL development, SOCIAL services, CHILD development, SOCIAL skills
Abstract

LEGO®-based therapy is a social skills development program aimed at children with autism spectrum disorder (ASD). A systematic review of the literature was conducted using PRISMA guidelines. PubMed, Scopus and Web of Science bibliographic databases were searched from their date of inception to August 2020. The review included 19 studies. Studies were classified according to experimental designs (e.g., Randomized Control Trial, Non-Randomized Studies of Interventions and case report and series) and a narrative synthesis of each was provided, along with a critical discussion of the strengths and weaknesses of the available literature on the topic. Although LEGO®-based therapy appears a promising treatment for social interaction in ASD, the findings of LEGO®-based therapy studies should be interpreted and generalized with caution, due to the low quality of the studies and the small sample sizes. [ABSTRACT FROM AUTHOR]

Published
2021
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41. A novel multidimensional questionnaire for the assessment of emotional dysregulation in adolescents: Reactivity, Intensity, Polarity and Stability questionnaire–youth version (RIPoSt–Y)

Author

Elena Valente, Flavia Drago, Stefano Berloffa, Francesca Placini, Anna Rita Montesanto, Gianluca Sesso, Nina Loriaux, Agnese Molesti, Gabriele Masi, Simone Pisano, Annarita Milone, Valentina Viglione, Silvia Boldrini, Sesso, Gianluca, Milone, Annarita, Drago, Flavia, Viglione, Valentina, Berloffa, Stefano, Boldrini, Silvia, Loriaux, Nina, Valente, Elena, Molesti, Agnese, Placini, Francesca, Montesanto, Anna Rita, Pisano, Simone, and Masi, Gabriele

Subjects
Psychometrics, Adolescent, Bipolar disorder, Emotions, Concurrent validity, Reproducibility of Result, Emotional dysregulation, CBCL, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, medicine, Humans, ADHD, Surveys and Questionnaire, Reactivity (psychology), Emotion, Schools, Questionnaire, Reproducibility of Results, Construct validity, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Clinical Psychology, Convergent validity, Self Report, Psychology, Construct (philosophy), Psychometric, 030217 neurology & neurosurgery, Human, Clinical psychology
Abstract

Background The failure to regulate emotions, namely emotional dysregulation (ED), is a relevant construct in adolescent psychiatry, in terms of prognostic and developmental implications. We developed and validated a novel self-report questionnaire for the assessment of ED, the RIPoSt-Y, both in clinical and non-clinical samples. Methods Items selection and subscales construction were conducted on healthy controls (n=374), while test-retest reliability was evaluated in a subsample (n=72); internal consistency was examined both in the control group and in two clinical samples, respectively including patients with Bipolar Spectrum Disorders (BSD; n=44) and ADHD (n=34). Construct, concurrent and convergent validity were also assessed. Results Thirty-one items were finally retained, and three subscales were identified (Affective Instability, Emotional Reactivity, Interpersonal Sensitivity). Test-retest was significant for each subscale with moderate-to-good correlations, and internal consistency showed good-to-excellent coefficients. Construct validity was supported by significant differences between patients and controls and gender-related differences. Concurrent validity was confirmed through significant associations with two subscales of the CHT-Q, while convergent validity proved to be significant with the CBCL/YSR dysregulation-profile. Cut-offs were also computed to discriminate clinically significant scores of ED. Limitations The use of a school-based survey to recruit controls could have biased our results; gender distributions between clinical and non-clinical samples were significantly different. Conclusions Our novel questionnaire proved to be a valid and reliable tool able to assess the presence of ED in youths and to characterize this fundamental construct in its multidimensional facets.

Published
2021

42. The Role of Executive Functions in the Development of Empathy and Its Association with Externalizing Behaviors in Children with Neurodevelopmental Disorders and Other Psychiatric Comorbidities

Author

Antonio Narzisi, Pietro Muratori, Chiara Pfanner, Laura Ruglioni, Emanuela Inguaggiato, Gianluca Sesso, Gabriele Masi, Annarita Milone, Simone Pisano, Paola Cristofani, Pamela Fantozzi, Elena Valente, Lisa Polidori, Chiara Cristofani, Cristofani, Chiara, Sesso, Gianluca, Cristofani, Paola, Fantozzi, Pamela, Inguaggiato, Emanuela, Muratori, Pietro, Narzisi, Antonio, Pfanner, Chiara, Pisano, Simone, Polidori, Lisa, Ruglioni, Laura, Valente, Elena, Masi, Gabriele, and Milone, Annarita

Subjects
medicine.medical_treatment, media_common.quotation_subject, autism spectrum disorder, Empathy, Article, lcsh:RC321-571, 03 medical and health sciences, 0302 clinical medicine, Social cognition, medicine, 0501 psychology and cognitive sciences, empathy, attention deficit and hyperactivity disorder, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, media_common, General Neuroscience, 05 social sciences, executive functions, medicine.disease, Executive functions, Cognitive behavioral therapy, Behavior Rating Inventory of Executive Function, Prosocial behavior, disruptive behavior disorders, Autism spectrum disorder, Autism, Psychology, disruptive behavior disorder, 030217 neurology & neurosurgery, 050104 developmental & child psychology, Clinical psychology
Abstract

Executive functions have been previously shown to correlate with empathic attitudes and prosocial behaviors. People with higher levels of executive functions, as a whole, may better regulate their emotions and reduce perceived distress during the empathetic processes. Our goal was to explore the relationship between empathy and executive functioning in a sample of children and adolescents diagnosed with Attention Deficit and Hyperactivity Disorder alone or associated with comorbid Disruptive Behavior Disorders and/or Autism Spectrum Disorder. We also aimed to examine the role of empathic dimensions and executive skills in regulating externalizing behaviors. The 151 participants with ADHD were assigned to four groups according to their psychiatric comorbidity (either &ldquo, pure&rdquo, or with ASD and/or ODD/CD) and assessed by means of either parent- or self-reported questionnaires, namely the BRIEF&minus, 2, the BES, and the IRI. No questionnaire was found to discriminate between the four groups. Affective Empathy was found to positively correlate with Emotional and Behavioral Regulation competences. Furthermore, Aggressiveness and Oppositional Defiant Problems were positively associated with Executive Emotional and Behavioral Regulation competences. On the other hand, Rule-Breaking Behaviors and Conduct Problems were negatively associated with Affective Empathy and with Behavioral skills. Our study provides an additional contribution for a better understanding of the complex relationship between empathic competence and executive functions, showing that executive functioning and empathic attitudes interact with each other to regulate aggressive behaviors. This study further corroborates developmental models of empathy and their clinical implications, for which externalizing behaviors could be attenuated by enhancing executive functioning skills.

Published
2020

43. El desajuste entre la educación secundaria técnica y la Industria Naval provocado por el neoliberalismo durante la década de los 90 en Argentina. La consecuencia en el mercado laboral de los egresados de las escuelas técnicas : caso de estudio Escuela Técnica Naval de San Fernando

Author

Camblong, Jorge R., Abrevaya, Claudio, and Valente, Elena

Subjects
Industria naval, Menem, Carlos Saúl, Buenos Aires, Ley Federal de Educación, Inserción laboral, Argentina, San Fernando, Educación técnica, Neoliberalismo, Siglo XX-Segunda mitad, Escuela Técnica Naval de San Fernando
Abstract

La educación en Argentina ha pasado varias transformaciones desde sus inicios. Se estima que cada una de ellas ha buscado una mejora; sin embargo, esto no siempre se ha logrado. El presente trabajo de tesis enfoca, a partir de un estudio de caso, la problemática que trajo aparejada la Ley Federal de Educación implementada por el gobierno del presidente Carlos Saúl Menem en la década del 90. Sostenemos y demostramos en esta tesis que dicha ley ha sido consecuente y presionada por el Fondo Monetario Internacional. Esta desarticulación trajo aparejada para nuestra nación un sin número de problemas. El trabajo de investigación del que esta tesis da cuenta hizo énfasis en la problemática industrial que se sufre hasta estos días. En particular, consideró la relación entre la educación técnica y la industria local respecto del trabajo del egresado de escuelas técnicas, basado sobre el caso de la escuela técnica naval de San Fernando, provincia de Buenos Aires. El trabajo se encuentra estructurado en capítulos que siguen la lógica de una tesis. Al resumen le sigue el primer capítulo que contiene la introducción donde se establecen los temas básicos de la investigación: la definición del problema, las preguntas a responder, la hipótesis, los objetivos primarios y secundarios. El segundo capítulo explicita la metodología de trabajo. Los capítulos 3, 4 y 5 configuran lo relacionado al marco teórico, los antecedentes de los temas a investigar, recopila la historia de las escuelas técnicas en Argentina, busca las causas del cambio educativo en los 90, se plasma la estructura del sistema educativo técnico en Argentina, incluyendo el caso de la provincia de Buenos Aires. En los capítulos mencionados, se ponede manifiesto lo relacionado con el problema en el municipio de San Fernando. En el capítulo 6 se desarrolla el caso propiamente dicho, a partir de la evidencia de los datos surgidos en el campo. El capítulo 7, por su parte, genera la relación de los datos investigados con el contexto en el que se desarrollaron cronológicamente. Se brinda, así, una información que sustenta la tesis. En el octavo y último capítulo se desarrollan las conclusiones del trabajo. El recorte de la investigación se centra en el Municipio de San Fernando, en lo que sucedió con la industria naval y su relación con la inserción laboral del egresado de la educación técnica en la zona. Fil: Camblong, Jorge R. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas; Argentina. Fil: Abrevaya, Claudio. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas; Argentina. Fil: Valente, Elena. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Humanas; Argentina.

Published
2017

44. Diferencias en el proceso de desarrollo lector en niños de diferentes grupos socioeconómicos

Author

Fumagalli, Julieta Carolina, Barreyro, Juan Pablo, Jaichenco, Virginia Irene, Nothstein, Susana Beatriz, Pereira, María Cecilia, and Valente, Elena Amable

Subjects
LECTURA, DESARROLLO LECTOR, ESCRITURA, HUMANIDADES, Lingüística, NIÑO, Lengua y Literatura
Abstract

En este trabajo nos proponemos establecer si existen diferencias de rendimiento en una prueba de lectura de palabras y no palabras en niños pertenecientes a 1er grado, 3er grado y 5to grado de dos escuelas a la que asisten alumnos de diferente nivel socioeconómico. Fueron evaluados 183 niños de dos escuelas de la Ciudad Autónoma de Buenos Aires. Los sujetos respondieron las pruebas de lectura de palabras y no palabras del test LEE (Defior Citoler, Fonseca y Gottheil, 2006). Se realizó un análisis estadístico para comparar el desempeño de los niños según grado (1ero, 3er y 5to) y según escuela (Escuela Privada nivel socioeconómico medio/ Escuela Pública nivel socioeconómico bajo) que mostró diferencias tanto entre los grupos etarios como entre los grupos según su procedencia socioeconómica. Asimismo, se hallaron diferencias en el modo de lectura que permiten sacar conclusiones sobre el uso de distintas estrategias lectoras que discutiremos a la luz de los modelos actuales de lectura. Fil: Fumagalli, Julieta Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Lingüística; Argentina Fil: Barreyro, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Psicología. Instituto de Investigaciones; Argentina Fil: Jaichenco, Virginia Irene. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Lingüística; Argentina

Published
2016

45. [Origins and evaluation of youth narcissism].

Author

Muratori P, Milone A, Buonanno C, Ianni S, Inguaggiato E, Levantini V, Pisano S, Valente E, and Masi G

Subjects
Adolescent, Child, Child, Preschool, Humans, Mythology, Aggression, Attention Deficit and Disruptive Behavior Disorders psychology, Mood Disorders psychology, Narcissism, Self Concept
Abstract

Recently, studies have focused on narcissism as a personality trait, which can be detected during childhood, and can lead to negative outcomes, such as emotional and behavioral problems. After illustrating the main hypotheses on the development of narcissistic traits in children, this paper aims to outline the relation between narcissism, self-esteem and emotional, and behavioral problems in children. Finally, are presented measures for the assessment of narcissistic traits in children and adolescents.

Published
2020
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