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为优化平面回转筛的结构和工艺参数，提高组合清理筛的筛分处理量和筛分效率，采用离散元软件EDEM对组合清理筛的平面回转筛分过程进行模拟仿真，探究颗粒在筛分过程中的运动规律，并仿真分析了回转半径、回转速度和筛面倾角对组合清理筛筛分处理量和筛分效率的影响。结果表明，提高回转半径、回转速度和筛面倾角均可提高组合清理筛筛分处理量，但会降低筛分效率（物料提取率和除杂率）。在回转速度为420 r/min左右、回转半径为20 mm左右、筛面倾角为7°~ 9°时，组合清理筛的筛分效率较好，筛分处理量也较大。In order to optimize the structure and process parameters of the rotary sieve classifier and improve the screening capacity and screening efficiency of the combined cleaning screen, the discrete element software EDEM was used to simulate the rotary screening process of the combined cleaning screen. The movement pattern of particles in the screening process was explored, and the effects of the radius of rotation, the rotation speed and the inclination angle of the screen surface on the screening capacity and screening efficiency of the combined cleaning screen were simulately analyzed. The results showed that increasing the radius of rotation, rotation speed and inclination angle of the screen surface could increase the screening capacity of the combined cleaning screen, but reduced the screening efficiency (material extraction rate and impurity removal rate). When the rotary speed was about 420 r/min, the radius of rotation was about 20 mm, and the inclination angle of the screen surface was 7°-9°, the screening efficiency of the combined cleaning screen was better, and the screening capacity was also larger.

BACKGROUND: Osteosarcoma has a complex pathogenesis and a poor prognosis. While advancements in medical technology have led to some improvements in the 5-year survival rate, substantial progress in its treatment has not yet been achieved. OBJECTIVE: To screen key molecular markers in osteosarcoma, analyze their relationship with osteosarcoma treatment drugs, and explore the potential disease mechanisms of osteosarcoma at the molecular level. METHODS: GSE99671 and GSE284259 (miRNA) datasets were obtained from the Gene Expression Omnibus database. Differential gene expression analysis and Weighted Gene Co-expression Network Analysis (WGCNA) on GSE99671 were performed. Functional enrichment analysis was conducted using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes separately for the differentially expressed genes and the module genes with the highest positive correlation to the disease. The intersection of these module genes and differentially expressed genes was taken as key genes. A Protein-Protein Interaction network was constructed, and correlation analysis on the key genes was performed using CytoScape software, and hub genes were identified. Hub genes were externally validated using the GSE28425 dataset and text validation was conducted. The drug sensitivity of hub genes was analyzed using the CellMiner database, with a threshold of absolute value of correlation coefficient |R| > 0.3 and P < 0.05. RESULTS AND CONCLUSION: (1) Differential gene expression analysis identified 529 differentially expressed genes, comprising 177 upregulated and 352 downregulated genes. WGCNA analysis yielded a total of 592 genes with the highest correlation to osteosarcoma. (2) Gene Ontology enrichment results indicated that the development of osteosarcoma may be associated with extracellular matrix, bone cell differentiation and development, human immune regulation, and collagen synthesis and degradation. Kyoto Encyclopedia of Genes and Genomes enrichment results showed the involvement of pathways such as PI3K-Akt signaling pathway, focal adhesion signaling pathway, and immune response in the onset of osteosarcoma. (3) The intersection analysis revealed a total of 59 key genes. Through Protein-Protein Interaction network analysis, 8 hub genes were selected, which were LUM, PLOD1, PLOD2, MMP14, COL11A1, THBS2, LEPRE1, and TGFB1, all of which were upregulated. (4) External validation revealed significantly downregulated miRNAs that regulate the hub genes, with hsa-miR-144-3p and hsa-miR-150-5p showing the most significant downregulation. Text validation results demonstrated that the expression of hub genes was consistent with previous research. (5) Drug sensitivity analysis indicated a negative correlation between the activity of methotrexate, 6-mercaptopurine, and pazopanib with the mRNA expression of PLOD1, PLOD2, and MMP14. Moreover, zoledronic acid and lapatinib showed a positive correlation with the mRNA expression of PLOD1, LUM, MMP14, PLOD2, and TGFB1. This suggests that zoledronic acid and lapatinib may be potential therapeutic drugs for osteosarcoma, but further validation is required through additional basic experiments and clinical studies. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Research of Soil & Water Conservation is the property of Institute of Soil & Water Conservation, Chinese Academy of Sciences & Ministry of Water Resources and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Uranium Mining & Metallurgy is the property of Uranium Mining & Metallurgy Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Pediatric Surgery is the property of Journal of Clinical Pediatric Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Southeast University / Dongnan Daxue Xuebao is the property of Journal of Southeast University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Tunnel Construction / Suidao Jianshe (Zhong-Yingwen Ban) is the property of Tunnel Construction Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Absorbent hydrogel is currently a focal point in scientific research due to its excellent water absorption and retention properties. It is widely utilized in various fields such as medical, hygiene, agriculture, and environmental protection for applications including dressings, diapers, moisturizers, and plant cultivation substrates. This experiment employs acrylic acid and acrylamide as monomers to prepare an innovative hydrogel towel via photo-initiated free radical polymerization. The resulting hydrogel towel exhibits superior mechanical properties, including easy folding and cutting, along with traditional hydrogel’s high water absorbency. Additionally, the experiment incorporates scanning electron microscopy for characterization, providing students with practical experience in instrumental analysis relevant to undergraduate comprehensive chemical laboratories. Furthermore, the creation of vibrant, colorful transparent hydrogels through dye adsorption experiments not only enhances the visual appeal of the project but also serves to ignite students’ interest and passion for chemistry. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Natural Disasters is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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China is a major producer and consumer of vegetable oils, and the processing of oilseeds generates a large amount of by-products such as vegetable oil deodorizer distillate, soapstock, and acid oil. These by-products are rich in active substances like phytosterols, natural vitamin E, and squalene, which have biological functions such as regulating cholesterol metabolism, antibacterial, antiinflammatory, and antioxidant properties, as well as promoting animal growth and improving the quality of animal products. Therefore, extracting natural active substances from vegetable oil processing byproducts and conducting research and application on their utilization as feed resources can help address many challenges currently faced by the feed development and livestock industry. This paper focuses on the latest research reports on phytosterols, natural vitamin E, and squalene in vegetable oils used in livestock and poultry production, analyzing their application effects and mechanisms of action, with the aim of providing theoretical basis and practical guidance for healthy animal farming. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Engineering for Thermal Energy & Power / Reneng Dongli Gongcheng is the property of Journal of Engineering for Thermal Energy & Power and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A lightweight semantic segmentation model Faster DeeplabV3+ based on DeeplabV3+ network was improved to address the issues of large parameter count, slow computation speed, and low efficiency in traditional semantic segmentation models. The Faster DeeplabV3 + model used lightweight MobilenetV2 instead of Xception as the backbone feature extraction network, significantly reducing the number of parameters and improving computational speed. Using the combination of deep separable convolution (DSC) and air space pyramid expansion convolution (ASPP), a new depth separable dilated convolution (DSD-Conv) was developed, namely, the depth separable empty space pyramid module (DP-ASPP), which expanded the receptive field while reducing the original convolution parameters and facilitating faster operation. In order to enhance the sensitivity and accuracy of the network in extracting feature information from different dimensions, a dual attention mechanism module was added for processing low-level and high-level feature maps generated in the coding region. Two loss functions, cross entropy and Dice Loss, were integrated to provide more comprehensive and diverse optimization for the model. The improved model was tested on the PASCAL VOC 2012 dataset. The experimental results show that the average intersection to union ratio increases from 76.57% to 79.07%, and the segmentation accuracy increases from 91.2% to 94.3%. The network parameter count (parameters) of the improved model is reduced by 3.86×106, and the floating-point computational load (GFLOPs) is decreased by 117.98 G. The proposed algorithm significantly reduces parameter count and improves computational speed, while also optimizing the segmentation effect. [ABSTRACT FROM AUTHOR]

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mountain Research (10082786) is the property of Mountain Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Industrial Water Treatment is the property of CNOOC Tianjin Chemical Research & Design Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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We present predictions for the high-redshift halo–galaxy–supermassive black hole (SMBH) connection from the Trinity model. Matching a comprehensive compilation of galaxy (0 ≤ z ≤ 13) and SMBH data sets (0 ≤ z ≤ 6.5), Trinity finds: (1) The number of SMBHs with M • > 109 M⊙ in the observable Universe increases by five orders of magnitude from z ∼ 10 to z ∼ 2, and by another factor of ∼3 from z ∼ 2 to z  = 0; (2) The M • > 109 and 1010 M⊙ SMBHs at z ∼ 6 live in haloes with ∼(2 − 3) and (3 − 5) × 1012 M⊙; (3) the newly discovered JWST AGN candidates at 7 ≲ z ≲ 11 are overmassive compared to the intrinsic SMBH mass–galaxy mass relation from Trinity , but they are still broadly consistent with Trinity predictions for flux limited AGN samples with Lauer bias. This bias favours the detection for overmassive SMBHs due to higher luminosities at a fixed Eddington ratio. However UHZ1's M •/ M * ratio is still some 1 dex higher than Trinity AGNs, indicating a discrepancy; (4) Trinity underpredicts the number densities of GN-z11 and CEERS_1019 analogues. But given the strong constraints from existing data in Trinity , the extra constraint from GN-z11 and CEERS_1019 does not significantly change trinity model results. (5) z  = 6–10 quasar luminosity functions will reduce uncertainties in the trinity prediction of the z  = 6–10 SMBH mass–galaxy mass relation by up to ∼0.5 dex. These luminosity functions will be available with future telescopes, such as Roman and Euclid. [ABSTRACT FROM AUTHOR]

In this study, four light models including rectangular hyperbola model, non-rectangular hyperbolic model, modified rectangular hyperbolic model and exponential model were jointly adopted to evaluate the photosynthetic parameters and light response fitting curves of six Callicarpa Linn. species in southern subtropical regions. By comparison of the light saturation point (LSP), light compensation point (LCP), maximum net photosynthetic rate (P), dark respiration rate (R) and apparent quantum efficiency (AQE), as well as the coefficient of determination (R), root mean square error (RMSE) and mean absolute error (MAE) derived from the four models, the most suitable light response models for these six plants were obtained. The results demonstrated that the modified rectangular hyperbolic model performed the best fitting ability for the photosynthetic study of the six Callicarpa species, and the highest light utilization ability under both strong and weak light belonged to C. formosana, and the highest photosynthetic efficiency was found in C. japonica var. Luxurians. In summary, these six Callicarpa species showed both interspecific variability and interspecific similarity in light utilization capacity, and the four light response models differed greatly in the calculation of the photosynthetic potential, however, there was consistency in the model's goodness-of-fit and fitting accuracy. [ABSTRACT FROM AUTHOR]

Copyright of Bearing is the property of Bearing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Current Biotechnology (2095-2341) is the property of Chinese Academy of Agricultural Sciences, Institute of Biotechnology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Application Research of Computers / Jisuanji Yingyong Yanjiu is the property of Application Research of Computers Edition and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to investigate the effects of freeze-thaw action on physical and mechanical properties and internal fracture damage of sandstone, freeze-thaw cycle tests were carried out on sandstone at different temperature range, and acoustic emission tests were carried out on freeze-thaw damaged rocks under uniaxial loading, so as to study the influence of freeze-thaw temperature range on physical and mechanical parameters and acoustic emission characteristics of rock. The results show that the temperature range increases with the freeze-thaw cycle, the mass loss rate and the change rate of P-wave velocity on the whole show a trend of first steep and then slowly rising, declining peak intensity and peak strain of the sandstone gradually increase, the uniaxial compressive strength and elastic modulus decreases, and the same freezing and thawing temperature range of the influence of elastic modulus under uniaxial compressive strength is more significant, and Poisson's ratio shows a trend of gradual increase. With the increase of freeze-thaw temperature range, the acoustic emission ringing count showed a gradual increasing trend, the cumulative ringing count gradually steepened, the silence period became smaller, the acoustic emission distribution time range gradually decreased, and the peak frequency showed a trend of low frequency development. The research results provide experimental basis for predicting engineering stability of rock mass in cold area. [ABSTRACT FROM AUTHOR]

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Copyright of China Synthetic Fiber Industry is the property of Sinopec Baling Petrochemical Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)