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Currently, the effective stop of parenchymal bleeding that has developed for various reasons: trauma, planned and emergency surgical interventions, is a serious challenge for modern clinical surgery. Today, in the arsenal of doctors there are a large number of hemostatic agents that affect the coagulation process, however, local hemostatics attract much attention, since they have a significant advantage - the absence of a systemic effect on the blood coagulation system. The objective: in a comparative aspect, to study the effectiveness of two-component sponge hemostatic agents in the model of marginal liver resection in vivo. Materials and methods. In a comparative aspect, we studied the hemostatic activity of samples of local application hemostatic agents "TachoComb" (No. 1), prototypes of two-layer spongy hemostatic agents based on sodium salt of carboxymethylcellulose of various viscosities (No. 2), Surgicel Fibrillar. Rats under inhalation anesthesia underwent a median laparotomy, modeled marginal resection of the left lobe of the liver. Bleeding was stopped by applying the compared samples, while recording the amount of blood loss and bleeding time. In order to assess the statistical significance of differences between study groups, the Mann-Whitney test (p≤0.05) was used. Results. The minimum time to stop bleeding was noted in group No. 2. When comparing the volume of blood loss, no statistically significant differences were found. Conclusion. The use of samples of two-layer sponge hemostatic agents developed and tested in the experiment based on the sodium salt of carboxymethyl cellulose of various viscosities in stopping parenchymal bleeding in laboratory animals is not inferior to the currently used local hemostatics in terms of blood loss and statistically significantly accelerates the process of stopping bleeding.

The paper contains the analysis of foreign practice in collecting customs debt and other payments from foreign individuals when placing goods and vehicles for personal use under the customs procedure of temporary admission and not re-exported. The experience of the countries of the European Union and Switzerland in this area is presented. The characteristics of the measures used abroad to ensure the customs payments and debt collection are highlighted (security for the customs payments as a guarantee, a cash deposit or other forms; signs, labels (seals), etc.). A comparative analysis of the measures used by the customs authorities of foreign countries and the Russian Federation to ensure the customs payments and debt collection is carried out.

The article analyzes the areas of customs activity, the improvement of the effectiveness of which depends on the use of advanced (innovative) technologies. The paper defines the essence of customs activity through the prism of the tasks facing the customs service and the functions they implement. The author presents modern information technologies (services) introduced into the activities of the customs authorities, such as: service CPS ”Semantics”; analysis service based on artificial intelligence of fluoroscopic images obtained using inspection and screening systems; a centralized version of the automated information system of customs (AIS ”AIST-M”) and others. The publication defines the prospects for the use of advanced information technologies in customs activities.