144 results on '"Freude, Kristine"'
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2. FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms
3. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
4. Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes
5. CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice
6. Distinct calcium sources regulate temporal profiles of NMDAR and mGluR-mediated protein synthesis
7. Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs
8. The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression
9. Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy
10. Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus
11. Astrocytes: The Stars in Neurodegeneration?
12. Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer’s Disease
13. Animal and Cellular Models of Alzheimer's Disease.
14. Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease.
15. Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease
16. Implications of SNP-triggered miRNA dysregulation in Schizophrenia development
17. Metabolic effect of the retina in a murine model of AD
18. Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies
19. Fordele og ulemper ved anvendelse af autologe versus allogene stamceller til behandling af artrose
20. Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC‐derived models of Alzheimer's disease
21. Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease
22. Potential Retinal Biomarkers in Alzheimer’s Disease
23. Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology
24. Complexity of Sex Differences and Their Impact on Alzheimer’s Disease
25. Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons
26. USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons
27. Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer’s disease neurons
28. Metabolic effects of the retina in a murine model of AD (TgSwDI)
29. Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease
30. FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and mechanisms
31. A34 NADPH oxidases putative roles in Huntington’s disease
32. USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient and CCCP-stressed human iPSC-derived neurons
33. Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants
34. The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes
35. Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop
36. RhoA Signaling in Neurodegenerative Diseases
37. Editorial: Metabolic Alterations in Neurodegenerative Disorders
38. G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes.
39. Retinal ganglion cells derived from retinal organoids – a contemporary model to study neurodegenerative retinal diseases
40. Decreased glucose metabolism and glutamine synthesis in the retina of a transgenic mouse model of Alzheimer’s disease
41. Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?
42. Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog
43. Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3
44. Oxidative Stress in Optic Neuropathies
45. Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease
46. APOE4 Affects Basal and NMDAR-Mediated Protein Synthesis in Neurons by Perturbing Calcium Homeostasis
47. A10 NAPDH oxidases (NOXs) exocytosis and its relevance in huntington’s disease (HD) pathology
48. A Protein-Centric View of in Vitro Biological Model Systems for Schizophrenia
49. CRISPR-Cas9 mediated knockout of MHC class I and II in porcine iPSC to generate non-immunogenic stem cells Supplemental Table 1
50. Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer’s Disease
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