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A silver-catalyzed decarboxylative trifluoromethylthiolation of secondary and tertiary carboxylic acids under mild conditions tolerates a wide range of functional groups. The reaction was dramatically accelerated by its performance in an aqueous emulsion, which was formed by the addition of sodium dodecyl sulfate to water. It was proposed that the radical, which was generated from the silver-catalyzed decarboxylation in the "oil-in-water" droplets, could easily react with the trifluoromethylthiolating reagent to form the product., (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

A silver-catalyzed decarboxylative trifluoromethylthiolation of secondary and tertiary carboxylic acids under mild conditions tolerates a wide range of functional groups. The reaction was dramatically accelerated by its performance in an aqueous emulsion, which was formed by the addition of sodium dodecyl sulfate to water. It was proposed that the radical, which was generated from the silver-catalyzed decarboxylation in the 'oil-in-water' droplets, could easily react with the trifluoromethylthiolating reagent to form the product. [ABSTRACT FROM AUTHOR]

The decarboxylative trifluoromethylthiolation of secondary and tertiary carboxylic acids tolerates a wide range of functional groups and is accelerated by performance in an aqueous emulsion. [ABSTRACT FROM AUTHOR]