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Your search keyword '"Srivastava, Swati"' showing total 1 results
Start Over Author "Srivastava, Swati" Topic chronic lymphocytic leukemia Topic genetic regulation Publication Year Range Last 50 years
1 results on '"Srivastava, Swati"'

1. Recent advances in microRNA-mediated gene regulation in chronic lymphocytic leukemia.

Author

Srivastava, Swati, Tsongalis, Gregory J., and Kaur, Prabhjot

Subjects
*CHRONIC lymphocytic leukemia, *MICRORNA, *GENETIC regulation, *PROGNOSTIC tests, *NON-coding RNA, *HEMATOPOIESIS
Abstract

Abstract: Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world and is a very clinically heterogeneous disease for which better prognostic biomarkers are needed. Current prognostic markers exhibit both biological and technical limitations. MicroRNAs (miRNAs) are small endogenous, non-coding 22-nucleotide regulatory RNAs that have been shown to modulate hematopoietic lineage differentiation and play important gene-regulatory roles in disease processes. In this manuscript, we review miRNA biology and the association of specific miRNAs with CLL. [Copyright &y& Elsevier]

Published
2013
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