365 results on '"Freude, Kristine"'
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2. FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms
3. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
4. Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes
5. CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice
6. Distinct calcium sources regulate temporal profiles of NMDAR and mGluR-mediated protein synthesis
7. Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs
8. The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression
9. Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy
10. Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus
11. Astrocytes: The Stars in Neurodegeneration?
12. Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer’s Disease
13. Animal and Cellular Models of Alzheimer's Disease.
14. Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease.
15. Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease
16. Implications of SNP-triggered miRNA dysregulation in Schizophrenia development
17. Metabolic effect of the retina in a murine model of AD
18. Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies
19. Fordele og ulemper ved anvendelse af autologe versus allogene stamceller til behandling af artrose
20. Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC‐derived models of Alzheimer's disease
21. Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease
22. Potential Retinal Biomarkers in Alzheimer’s Disease
23. Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology
24. Cellular bioenergetics in human iPSC–derived glutamatergic neurons in health and disease
25. Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer’s disease
26. Contributors
27. Contributors
28. Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia
29. Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges
30. Complexity of Sex Differences and Their Impact on Alzheimer’s Disease
31. Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons
32. Systems Biology and Stem Cell Pluripotency: Revisiting the Discovery of Induced Pluripotent Stem Cell
33. Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons
34. Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals
35. USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons
36. Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer’s disease neurons
37. Metabolic effects of the retina in a murine model of AD (TgSwDI)
38. Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease
39. FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and mechanisms
40. A34 NADPH oxidases putative roles in Huntington’s disease
41. USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient and CCCP-stressed human iPSC-derived neurons
42. Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants
43. The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes
44. Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop
45. RhoA Signaling in Neurodegenerative Diseases
46. Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development
47. Editorial: Metabolic Alterations in Neurodegenerative Disorders
48. G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes.
49. Retinal ganglion cells derived from retinal organoids – a contemporary model to study neurodegenerative retinal diseases
50. Decreased glucose metabolism and glutamine synthesis in the retina of a transgenic mouse model of Alzheimer’s disease
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