1. Fatigue und sensomotorische Instabilität: Neurologisch kontrollierte Konversion von Post-COVID-19-Patienten.
- Author
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Urban, Thomas, Reinhardt, Fritjof, Lohse, Peter, Spitzer, Stefan G., Rasche, Luise, and Reichmann, Heinz
- Subjects
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COGNITIVE therapy , *POST-acute COVID-19 syndrome , *DYSAUTONOMIA , *COVID-19 pandemic , *TREATMENT effectiveness - Abstract
Background: For the treatment of the symptoms of post-COVID-19 syndrome, no causal therapy is currently widely recommended according to evidence-based criteria. The overarching goal of the intervention study over a 3-year period (Q1-2021–Q4-2023) was to evaluate the changes in the key symptoms of fatigue and sensorimotor instability through individualized stress-controlled training therapy and through intensified cognitive behavioral therapy. Material and methods: In the 3‑year period 407 vaccinated nucleocapsid positive patients were treated at the Post-COVID-19 Center Lausitz (Senftenberg). In 78 (around 19%) fatigue/immunometabolic depression and sensorimotor instability were identified as the leading syndromes. The evaluation of the individualized stress-controlled training therapy was based on the specific post-COVID-19 syndrome and motor fatigue parameters. The secondary psychosomatic syndrome was assessed using cognitive fatigue parameters and cognitive behavioral therapy instruments. The investigation of -parameters influencing behavior took place in Q2-2023–Q4-2023 with a guide-supported qualitative interview among the participants. Results: The post-COVID-19 key symptoms "fatigue," "sensorimotor instability," "neuropsychiatric symptoms," "cardiac/autonomic dysfunction," and "pain" improved significantly in the overall cohort and in the gender-specific analysis. A deterioration occurred in "secondary psychosomatic symptoms". A therapeutic effect was demonstrated for all motor fatigue parameters for the entire cohort using the Cohen's d value. An intensification of cognitive behavioral therapy achieved positive effects through an increasing development of the patients' own activity and their self-control using persuasion and gamification. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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