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Background: Although post-menopausal obesity is an important public national health problem in Saudi Arabia, to date no study has evaluated the effects of weight reduction on biochemical & clinical parameters and quality of Life for obese Saudi post-menopausal women. Objective: The aim of this study was examine the effects of aerobic versus resisted exercise training effects upon systemic inflammation biomarkers and quality of life for obese post-menopausal Saudi women. Material and Methods: One hundred Saudi post-menopausal obese women participated in this study, their age ranged from 50-58 years and their body mass index (BMI) ranged from 30-35 kg/m2. All participants were divided into two equal groups: The first group received aerobic exercise training on treadmill where, the second group received resisted exercise training. Health-related quality of life (SF-36 HRQL), tumor necrosis factor– alpha(TNF-α), Interleukin-2(IL-2), Interleukin-4 (IL-4), Interleukin-6 (IL-6) and C-reactive protein (CRP) were measured before and after 3 months at the end of the study. Results: The mean values of SF-36 HRQL subscale scores were significantly increased, while the mean value of TNF-α, Il-2, IL-4, IL-6,CRP and BMI were significantly decreased in both groups after treatments. There were significant differences between mean levels of the investigated parameters in group (A) and group (B) after treatment with more changes in patients received aerobic exercise training. Conclusion: The current study provides evidence that aerobic exercise is more appropriate than resisted exercise training in modulating inflammatory cytokines and quality of life among obese post-menopausal women.Keywords: Aerobic exercise; resisted exercises; inflammatory cytokine; quality of life; obesity; menopause.

Representative “acute phase reactants” and a “clinical index” of synovial in flammation were determined in patients with various rheumatic diseases. The serum hexose-protein (PR) ratio, serum protein-bound hexose and seromucoid determinations were consistently found a more reliable indication of the extent of systemic inflammation than the other tests studied. Systemic inflammation, measured by “acute phase reactants,” paralleled the clinically determined synovial reaction only in patients with rheumatoid arthritis. Representative “reactantes de phase acute” e un “indice clinic” de inflammation synovial esseva determinate in patientes con vane morbos rheumatic. Le proportion de hexosa a proteina in le sero, le hexosa ligate a proteina seral, e le seromucoides se provava uniformemente plus fidel como indices del extension de inflammation systemic que le altere parametros studiate. Le inflammation systemic, mesurate per „reactantes de phase acute,” esseva parallel a1 clinicamente determinate reaction synovial solmente in patientes con arthritis rheumatoide.