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A study conducted in France between 2018 and 2023 analyzed the increasing rates of erm(B) and erm(N) in human Campylobacter coli and Campylobacter jejuni erythromycin-resistant isolates. The research identified mutations as the main resistance mechanism, with a rise in erm(N) and erm(B) positive isolates over the study period. The majority of these isolates were obtained from chicken, highlighting the importance of monitoring erythromycin-resistant strains in chicken meat production. The study was conducted by Lucie Benejat and colleagues at the National Reference Centre for Campylobacters & Helicobacters in Bordeaux, France. [Extracted from the article]

A recent report from the University of Bordeaux discusses the introduction of the hexafluoroisobutyl group into peptides and proteins, a modification that enhances hydrophobicity while maintaining overall structure. This research highlights a new one-step method for incorporating the hexafluoroisobutyl group using a liquid fluorinated reagent, opening up new possibilities in organofluorine chemistry, medicinal chemistry, and protein engineering. Funders for this study include Agence Nationale de la Recherche (ANR), Ministry of Higher Education & Scientific Research of Tunisia, and Region Nouvelle-Acquitaine. [Extracted from the article]

A recent study conducted at the University of Bordeaux in France focused on the development of an assessment tool to determine if clinical practice guidelines (CPGs) facilitate shared decision-making (SDM) in personalized medicine. The study utilized a Delphi consensus method with seven experts to adapt international consensus studies into a French assessment tool. The tool consists of 17 criteria to assess the integration of SDM in CPGs, aiming to improve patient-physician communication and decision-making processes. The research suggests that translations of the tool into other languages could expand its utility for assessing CPGs globally. [Extracted from the article]

A study conducted at the University Hospital of Bordeaux in France explored the prevalence of alexithymia, characterized by difficulty identifying and expressing emotions, in patients with drug-resistant epilepsy (DRE). The research found that 40.7% of patients with DRE exhibited alexithymia, with significant associations to depression and anxiety. The study highlights the importance of early identification and intervention for alexithymia to improve outcomes in patients with DRE. [Extracted from the article]