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The anxiety of doctoral students in school has consistently been a major concern in society and the medical community, stemming from pressures, such as the pursuit of identity within highly professional and fiercely competitive academic communities, the urgent drive for high-level original scientific research output, and the need to break through the limits of personal ability to complete in-depth academic training. Current research has focused on the prevalence of, causes of, and intervention strategies for anxiety among doctoral students, but it still exhibits deficiencies, such as overly generalized analytical methods, neglect of the diversity within the doctoral student population, and the incomplete theoretical framework for the mechanisms of influence. Therefore, our study aims to examine the anxiety status of different categories of doctoral students and to explore their anxiety intervention mechanisms. Specifically, we employ a mixed research method combining quantitative and qualitative approaches to address issues, such as the influencing factors of anxiety in different types of doctoral students, the mechanisms of action of each factor, and the formation of an influence mechanism framework. The results indicate that anxiety is prevalent among doctoral students, with the key influencing factors being gender, age, love and marriage pressure, and self-perception. Full-time and part-time doctoral students exhibit different anxiety states and causes on account of varying pressures related to graduation, employment, and family factors. Our research distinguishes the heterogeneity of anxiety among different types of doctoral students in China, innovatively constructing a set of anxiety intervention mechanisms for doctoral students. It aims to provide policy insights for the adjustment of their anxiety and hopes to offer novel perspectives and exemplary references for the theoretical research and practical exploration of doctoral students' anxiety in other countries around the world. [ABSTRACT FROM AUTHOR]

To a certain extent, theranostic nanoplatforms promote tumor treatment efficiency. However, timely monitoring of the critical stages and signal sustainability of the entire process is challenging. In this study, multi-chambered core/shell magnetic nanoparticles (MC-MNPs) as drug and imaging agent multi-loaded nanocarriers with a synergistic release function are reported. Supraparticles with stable chambers are formed by the supercooling self-assembly of several core/shell magnetic nanoparticles composed of amphiphilic copolymers as the core and hydrophilic magnetic iron oxide nanoparticles as the shell. Desalinized doxorubicin and coumarin 6 are stored in different cavities of nanocarriers, and chitosan is used as an outer encapsulation layer. Based on their construction properties, MC-MNPs can exhibit gradient-degraded and steady-released controllability in the tumor environment. Furthermore, real-time accumulation situations and full-time diagnostic signals of nanocarriers are thoroughly demonstrated using fluorescence imaging and T 2 -weighted magnetic resonance imaging before and after magnetic hyperthermia in targeted tumors under an alternating magnetic field. Thus, MC-MNPs as theranostic nanocarriers exhibit great potential for the timely monitoring and full-time guidance of tumor treatment., (© 2024 Wiley‐VCH GmbH.)