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The article presents a case study of the 2015 Paris Agreement on climate change, along with mentions the efforts for achieving consensus in multilateral international negotiations. It discusses the aim of agreement as to coordinate the international efforts to keep the effects of global warming to below two degree Celsius relative to the preindustrial level and to pursue efforts to limit them.

The article presents the discussion on tissue homeostasis requiring the coordinated activity of multiple cell types for initiating and then resolving inflammation. Topics include endoplasmic reticulum (ER) stress being a hallmark of inflammation and exacerbating tissue pathology across a broad range of human diseases; and initiating the active engagement of programmed cell death pathways.

Identifying a suitable water-soluble sacrificial layer is crucial to fabricating large-scale freestanding oxide membranes, which offer attractive functionalities and integrations with advanced semiconductor technologies. Here, we introduce a water-soluble sacrificial layer, "super-tetragonal" Sr 4 Al 2 O 7 (SAO T ). The low-symmetric crystal structure enables a superior capability to sustain epitaxial strain, allowing for broad tunability in lattice constants. The resultant structural coherency and defect-free interface in perovskite ABO 3 /SAO T heterostructures effectively restrain crack formation during the water release of freestanding oxide membranes. For a variety of nonferroelectric oxide membranes, the crack-free areas can span up to a millimeter in scale. This compelling feature, combined with the inherent high water solubility, makes SAO T a versatile and feasible sacrificial layer for producing high-quality freestanding oxide membranes, thereby boosting their potential for innovative device applications.