1. 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
- Author
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Kilgour, Marisa K., MacPherson, Sarah, Zacharias, Lauren G., Ellis, Abigail E., Sheldon, Ryan D., Liu, Elaine Y., Keyes, Sarah, Pauly, Brenna, Carleton, Gillian, Allard, Bertrand, Smazynski, Julian, Williams, Kelsey S., Watson, Peter H., Stagg, John, Nelson, Brad H., DeBerardinis, Ralph J., Jones, Russell G., Hamilton, Phineas T., and Lum, Julian J.
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GLYCOLYSIS , *ASCITIC fluids , *OVARIAN cancer , *CYTOTOXIC T cells , *ORGANIC cation transporters - Abstract
The article offers information about the immune regulatory metabolites are key features of the tumor microenvironment. It mentions a study that profiled tumor and T cells from tumor and ascites of patients with high-grade serous carcinoma (HGSC) to uncover the metabolomes of these distinct TME compartments.
- Published
- 2021
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