Search

Showing total 1 results

Refine your results

1 results

1. Role of AIM in Corynebacterium-induced granuloma formation in mice.

Author

Kuwata, Kazuhisa, Watanabe, Hisami, Yamamoto, Takashi, Miyazaki, Toru, and Naito, Makoto

Subjects
*APOPTOSIS, *MACROPHAGES, *CUTIBACTERIUM acnes, *GRANULOMA, *KILLER cells, *T cells
Abstract

A conference paper on the role of apoptosis inhibitor expressed by macrophages (AIM) in Corynebacterium-induced granuloma formation in mice is presented. Results reveal the poor repopulation of natural killer T (NKT) cells in middle and late stages of granuloma formation in AIM-/-mice. Apoptosis of NKT cells and T cells was more prominent in AIM-/- mice. These findings indicate that AIM regulates NKT and T cell apoptosis and recruitment and plays a vital role in granuloma formation.

Published
2004