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A letter to editor is presented in response to the article "The effectiveness of BCG vaccination in preventing Mycobacterium tuberculosis infection and disease in Greenland" by S. W. Michelsen, B. Soborg and colleagues in the 2014 issue.

A letter to the editor is presented in response to the article "Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score" by A.O. Clive et al published in the year 2014.

Presents several correspondence on medicine. Development of preoperative radiotherapy in rectal cancer; Techniques in removing ingrown toenails; Efficacy of propanol in treating hypertension.

Examines the impact of introducing a community psychiatric service on the adult psychiatric admissions in Nottingham, England. Categories of patient diagnosis; Correlation between the number of hospital beds used and the number of patient admissions; Effects of community psychiatric resource improvement on hospital bed used.

A letter to the editor is presented in response to the article "Effect of BCG Vaccination Against Mycobacterium Tuberculosis Infection in Children: Systematic Review and Meta-Analysis" by A. Roy and colleagues in the August 5, 2014 issue.

Relates an experience on the impact of computers on the diagnosis and treatment of diseases in Great Britain. Comparison between the symptoms of the disease with that of the patient and National Databank; Diagnosis of cholecystitis; Treatment for the abdominal pain.

The article focuses on the randomized phase 2a trial of the drug linezolid carried out in South Korea where 41 patients were recruited with sputum culturepositive pulmonary extensively drug-resistant tuberculosis.

Abstract Objective: To assess the efficacy of enzyme potentiated desensitisation in the treatment of severe summer hay fever poorly controlled by pharmacotherapy. Design: Double blind randomised placebo controlled parallel group study. Setting: Hospital in Hampshire. Participants: 183 participants aged between 18 and 64 with a history of severe summer hay fever for at least two years; all were skin prick test positive to timothy grass pollen. 90 randomised to active treatment; 93 randomised to placebo. Interventions: Active treatment: two injections of enzyme potentiated desensitisation, given between eight and 11 weeks apart, each comprising 200 Fishman units of β glucuronidase, 50 pg 1, 3 cyclohexanediol, 50 ng protamine sulphate, and a mixed inhaled allergen extract (pollen mixes for trees, grasses, and weeds; allergenic fungal spores; cat and dog danders; dust and storage mites) in a total volume of 0.05 ml buffered saline. Placebo: two injections of 0.05 ml buffered saline solution. Main outcome measures: Proportion of problem-free days; global rhinoconjunctivitis quality of life scores assessed weekly during pollen season. Results: The active treatment group and the placebo group did not differ in the proportion of problem-free days, quality of life scores, symptom severity scores, change in quantitative skin prick provocation threshold, or change in conjunctival provocation threshold. No clinically significant adverse reactions occurred. Conclusions: Enzyme potentiated desensitisation showed no treatment effect in this study. [ABSTRACT FROM AUTHOR]

Presents letters related to medicine. Necessity of qualified medical advisers to governing bodies in sports; Treatment of penicillinase-producing gonococci; Danger of obesity.

Focuses on the issue of health care. Identification of the psychiatric aspects of shoplifting; Antenatal diagnosis of the mucopolysaccharidosis; Improvement of hospital services.

Comments on several issues regarding medical care in Great Britain. Non-surgical management of peripheral vascular disease; Drugs for peptic ulcers; Infectivity of tuberculosis.