1. Five- and ten-year survival of squamous cell carcinoma of the head and neck in northern Thailand: a multivariate analysis.
- Author
-
Chakrabandhu, Somvilai, Bunyatisai, Walaithip, Sripan, Patumrat, Traisathit, Patrinee, and Chitapanarux, Imjai
- Subjects
ACADEMIC medical centers ,ACQUISITION of data methodology ,MOUTH tumors ,MULTIVARIATE analysis ,HEAD & neck cancer ,RETROSPECTIVE studies ,LARYNGEAL tumors ,OROPHARYNGEAL cancer ,CANCER patients ,MEDICAL records ,KAPLAN-Meier estimator ,DESCRIPTIVE statistics ,SQUAMOUS cell carcinoma ,PROPORTIONAL hazards models ,HYPOPHARYNGEAL cancer - Abstract
Aim: To report 5- and 10-year overall survival (OS) outcomes of squamous cell carcinoma of the head and neck and identify prognostic factors. Methods: Data on 2,095 patients at Maharaj Nakorn Chiang Mai Hospital, Thailand between 2007 and 2014 were analysed using the Kaplan–Meyer method to estimate 5- and 10-year OS rates. Cox proportional hazard regression models were applied to assess the independent prognostic factors of survival. Results: 8·7% had hypopharyngeal cancer, 19·7% laryngeal, 53·3% oral cavity and 18·3% oropharyngeal. Two-thirds of the patients had locally advanced stage (III–IVB). Five- and ten-year OS rates were 30·1 and 22·8%, respectively. Conclusions: Cancer site, stage and age at diagnosis were associated with mortality, highlighting the importance of prevention and early detection. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF