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1. RNA Interference: The Fragile X Syndrome Connection

Author

Carthew, Richard W.

Subjects
*FRAGILE X syndrome, *MESSENGER RNA, *PROTEINS
Abstract

Fragile X syndrome is caused by loss of expression of FMRP, a protein proposed to act as a regulator of mRNA translation which promotes synaptic maturation and function. Now FMRP has been found to associate with the RNP complex that mediates post-transcriptional silencing by RNAi. [Copyright &y& Elsevier]

Published
2002
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