Search

Your search keyword '"Shrivastava, Sushant K."' showing total 1 results
Start Over Author "Shrivastava, Sushant K." Publisher chulalongkorn university
1 results on '"Shrivastava, Sushant K."'

1. Conjugation of some NSAIDs with 5-phenyl-2-aminothiazole for reduced ulcerogenicity.

Author

Verma, Abhilasha, Das, Nirupam, Dhanawat, Meenakshi, and Shrivastava, Sushant K.

Subjects
*ANALGESICS, *CARBONYL compounds, *THIAZOLES, *AMINO compounds, *ACID deposition, *AMIDES, *ANTI-inflammatory agents, *NITROGEN, *THERAPEUTIC complications
Abstract

Analgesic drugs containing free acidic group were reacted with N, N' carbonyldiimidazole to prepare the acylimidazole derivatives. They were further reacted with 5-phenyl-2-amino thiazole nucleus to obtain the corresponding amides. All the compounds were found to retain analgesic-antiinflammatory activities with much lesser NSAID-induced GI complications when compared with the standard. [ABSTRACT FROM AUTHOR]

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results