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Complexes Na 3 [Ag(NHC R ) 2 ], 2a-e and 2b'-c', where NHC R is a N-heterocyclic carbene of the 2,2'-(1H-2λ 3 ,3λ 4 -imidazole-1,3-diyl)dicarboxylate type, were prepared by treatment of compounds HL R , 1a-e and 1b'-c' (2-(1-(carboxyalkyl)-1H-imidazol-3-ium-3-yl)carboxylate), with silver oxide in the presence of aqueous sodium hydroxide. They were characterized by analytical, spectroscopic (infrared, IR, 1 H and 13 C nuclear magnetic resonance, NMR, and circular dichroism) and X-ray methods (2a). In the solid state, the anionic part of complex 2a, [Ag(NHC H ) 2 ] 3- , shows a linear disposition of C carbene -Ag-C carbene atoms and an eclipsed conformation of the two NHC ligands. The proposed bis(NHC) nature of the silver complexes was maintained in solution according to NMR and density functional theory (DFT) calculations. The cytotoxic activity of compounds 2 was evaluated against four cancer cell lines and one non-cancerous cell line and several structure-activity correlations were found for these complexes. For instance, the activity decreased when the bulkiness of the R alkyl group in Na 3 [Ag(NHC R ) 2 ] increased. More interesting is the detected chirality-anticancer relationship, where complexes Na 3 [Ag{(S,S)-NHC R } 2 ] (R = Me, 2b; i Pr, 2c) showed better anticancer activity than those of their enantiomeric derivatives Na 3 [Ag{(R,R)-NHC R } 2 ] (R = Me, 2b'; i Pr, 2c')., (Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.)

The electrochemical treatment of a synthetic tannery wastewater, prepared with several compounds used by finishing tanneries, was studied in chloride-free media. Boron-doped diamond (Si/BDD), antimony-doped tin dioxide (Ti/SnO(2)-Sb), and iridium-antimony-doped tin dioxide (Ti/SnO(2)-Sb-Ir) were evaluated as anode. The influence of pH and current density on the treatment was assessed by means of the parameters used to measure the level of organic contaminants in the wastewater; i.e., total phenols, chemical oxygen demand (COD), total organic carbon (TOC), and absorbance. Results showed that faster decrease in these parameters occurred when the Si/BDD anode was used. Good results were obtained with the Ti/SnO(2)-Sb anode, but its complete deactivation was reached after 4h of electrolysis at 25 mA cm(-2), indicating that the service life of this electrode is short. The Ti/SnO(2)-Sb-Ir anode is chemically and electrochemically more stable than the Ti/SnO(2)-Sb anode, but it is not suitable for the electrochemical treatment under the studied conditions. No significant changes were observed for electrolyses performed at different pH conditions with Si/BDD, and this electrode led to almost complete mineralization after 4h of electrolysis at 100 mA cm(-2). The increase in current density resulted in faster wastewater oxidation, with lower current efficiency and higher energy consumption. Si/BBD proved to be the best electrodic material for the direct electrooxidation of tannery wastewaters., (Copyright 2010 Elsevier B.V. All rights reserved.)

Lung cancer is a frequent pathology among women, as a result of tobacco increase. Lung cancer among pregnant women is especially rare when revealed by Pancoast-Tobias syndrome. Foetal injury is possible. The approach is multidisciplinary. Prognosis is bad.

This study is performed on a population of pregnant women during the second trimester of their pregnancy. The aim of this study is to demonstrate that clinical symptoms noticeable by the obstétricians during their consultations. Eight hundred and fifty-three patients have been involved in this study by responding to an anonymous questionnary. Hundred and seventy-five patients(groupI) have been abuse either physically or psychologically or sexually. The study shows that there is a strong difference between the groupI and the group without abuse in their medical past history (678 patients) about the occurracy of several disorders. The most frequently observed troubles are sexuals disorders, school failures, deficients relationship with others persons, anxiety and troubles of humor. We can concluded, about those clinical manifestations, that they do exist during pregnancy and probably thoses symptoms are linked to traumatism occured during their past history. Obstetricians must look after thoses symptoms very seriously to propose a good management of the pregnancy either about their psychological problems or about the social environnement in which they live.

Primary breast lymphoma is a difficult diagnosis because it is very rare. It can be found during pregnancy. Its diagnosis is often delayed. Treatment combines radiotherapy and chemotherapy. Prognosis is generally bad. Therefore, it is most important to examine breasts during pregnancy.

Heterotopic pregnancy was a rare pathology many years ago, but its survey is more frequently observed during last years with Assisted Reproduction Technics. We report a case of a heterotopic pregnancy with a rare symptomatology, with in the front plan a miscarriage. It's diagnostic is difficult and occurred very late. The main treatment consists to perform a salpingotomy under laparoscopy. However laparotomy treatment is frequently performed in relation to the late time of diagnosis.

Objectives: To study risk factors and perinatal outcomes in short interpregnancy intervals., Materials and Methods: Retrospective study, between 1995 and 2001, comparing women with short interpregnancy intervals (<6 months, n = 192) and women controls (interpregnancy intervals between 18 and 23 months, n = 210). The analysis included demographical and social factors, maternal medical histories and perinatal outcomes for the 2(nd) pregnancy., Results: Risk factors of short interpregnancy intervals were: young age, no anterior contraception, celibacy, medical history of intrauterine fetal death or medical pregnancy termination and high parity and gestity. The patients at risks of short interpregnancy intervals often belong to little supported social background, are generally without profession and often leave against medical opinion. The short interval between pregnancies is associated to a high score of prematurity (19% vs 8%, OR = 2.8, p < 0.001)., Conclusion: These data suggest that obstetricians and other care providers need to be alert to these identifiable risk factors and then direct preventive strategies during and after pregnancy.