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Your search keyword '"Mousset, Sabine"' showing total 5 results
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5 results on '"Mousset, Sabine"'

2. Adressen

Author

Alt-Epping, Bernd, primary, Fuxius, Stefan, additional, Wedding, Ulrich, additional, Arndt, Volker, additional, Bergbold, Susanne, additional, Delorme, Stefan, additional, Demmerle, Christina, additional, Frickhofen, Norbert, additional, Haberkorn, Uwe, additional, Henke, Oliver, additional, Hermann, Robert, additional, Hermann, Silke, additional, Kahl, Christoph, additional, Kleiß, Matthias, additional, Koch, Herbert, additional, Lordick, Florian, additional, Mons, Ute, additional, Mousset, Sabine, additional, Richter, Konrad Klaus, additional, Winkler, Eva, additional, Wolff, Hendrik A., additional, and Zettl, Stefan, additional

Published
2021
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3. Adressen

Author

Alt-Epping, Bernd, primary, Arndt, Volker, additional, Delorme, Stefan, additional, Frickhofen, Norbert, additional, Friedrich, Susanne, additional, Fuxius, Stefan, additional, Haberkorn, Uwe, additional, Haverkamp, Uwe, additional, Hermann, Robert M., additional, Hermann, Silke, additional, Kahl, Christoph, additional, Kleiß, Matthias, additional, Koch, Herbert, additional, Lordick, Florian, additional, Maier, Bernd Oliver, additional, Mons, Ute, additional, Mousset, Sabine, additional, van Oorschot, Birgitt, additional, Prott, Franz-Josef, additional, Richter, Konrad K., additional, Wedding, Ulrich, additional, Winkler, Eva C., additional, Wolff, Hendrik A., additional, and Zettl, Stefan, additional

Published
2017
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5. Enumeration of functionally active anti-Aspergillus T-cells in human peripheral blood.

Author

Beck O, Koehl U, Tramsen L, Mousset S, Latgé JP, Müller K, Schwabe D, Bader P, Klingebiel T, and Lehrnbecher T

Subjects
Adolescent, Adult, Antigens, Fungal, Aspergillosis etiology, Aspergillosis microbiology, CD4-Positive T-Lymphocytes microbiology, Case-Control Studies, Cells, Cultured, Child, Female, Humans, Immunologic Memory, Male, Phenotype, Reproducibility of Results, Time Factors, Aspergillosis immunology, Aspergillus fumigatus immunology, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes immunology, Cytokines metabolism, Flow Cytometry, Hematopoietic Stem Cell Transplantation adverse effects, Immunophenotyping methods
Abstract

Invasive aspergillosis remains a life-threatening complication in patients undergoing allogeneic stem cell transplantation (SCT). Since CD4(+) T-cells provide a critical secondary defense against Aspergillus spp., the quantification of "functional" anti-Aspergillus T-cells might be important in the clinical care of allogeneic transplant patients. We present a rapid, simple and reproducible method to enumerate functionally active, cytokine-producing anti-Aspergillus T-cells in peripheral blood by means of flow cytometry, by which these cells were also phenotypically characterized as memory CD4(+) T-cells. When using 100,000 PBMCs and requiring a minimum of 50 events, at least one anti-Aspergillus T-cell among 1000 CD4(+) T-cells can be detected. Compared to healthy individuals, the number of anti-Aspergillus T-cells in patients up to one year after SCT was significantly lower. The presented method might help to define hematopoietic transplant recipients who will benefit from adoptive transfer of anti-Aspergillus T cells.

Published
2008
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