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Recently, the Internet of Things (IoT) technology has played a crucial role in our daily lives. It ensures the automatic transfer and response between various smart devices. Likewise, it enhances connections within networks and provides access to different information and data, making our lives easier. The innovation of the humanoid robot, which utilizes IoT technology, positively impacts our daily activities in many ways. However, compromising these robots may raise privacy and security concerns. This work aims to increase security awareness for robot users by highlighting and conducting common possible cyberattacks on Junior Zenbo robots using open, unsecured ports and weak Wi-Fi security, leading attackers to gain unauthorized access. In addition, the study intends to provide a comprehensive forensic guide that has been illustrated, detailing major Zenbo robot artifacts that can support forensic examiners in their investigations. [ABSTRACT FROM AUTHOR]

In December 2019, an outbreak of a novel pneumonia-like illness, COVID-19 (C-19), emerged in Wuhan, China. In March 2020, as the incidence of C-19 rose, the Israeli government, like that of other nations, declared a national state of emergency, and a full, general lockdown was announced. The purpose of this study is to determine the incidence and characteristics of pediatric maxillofacial trauma presentation during the 2020 C-19 lockdown restrictions and compare them to periods outside lockdown between 2019 and 2020 (pre-C-19). A retrospective cohort study was conducted and included all pediatric patients (0-18 years) referred to the emergency department (ED) at Tzafon Medical Center, Israel, and diagnosed with maxillofacial injuries. Patients with missing demographic data and patients who did not complete the medical examination were excluded. The exposure variable is the date of injury—2020 C-19 lockdown period compared to the previous year (pre-C-19). The main outcome variable was the number of pediatric maxillofacial trauma ED arrivals out of total pediatric ED arrivals and out of total maxillofacial ED arrivals. Covariates included patient demographics, etiology, and place of injury. The association between categorical variables was tested using the Fisher exact test or χ2 test for binary variables with relative risk when appropriate, logistic regression model used to predict outcome variable. P values were 2-tailed and statistical significance was defined as P <.05. The study sample comprised 1174 patients. Relative risk of presenting with oral and maxillofacial trauma out of all pediatric ED patients was 1.85 comparing C-19 period to pre-C-19 period (confidence interval [1.65; 2.073], P <.0001). Most of the injuries recorded during the C-19 restrictions occurred in the domestic environment (56.1% compared to 47.5% in pre-C-19, P <.001). Incidences necessitating treatment increased from 45.8 to 55% during C-19 (P =.002). During C-19, there was a higher rate of pediatric injuries compared to pre-C-19. The incidence of domestic oral and maxillofacial injuries increased despite the considered home safety. [ABSTRACT FROM AUTHOR]

The current work describes how 2D layered materials, such as MoS 2 and WS 2 , might improve the de/re-hydrogenation kinetics of MgH 2. In the presence of WS 2 catalyst, desorption of MgH 2 begins at 277 °C, with a hydrogen storage capacity of 5.95 wt%, while the onset desorption temperature of MgH 2 catalyzed by MoS 2 is 330 °C. In just 1.3 min at 300 °C under 13 atm hydrogen pressure, the MgH 2 -WS 2 absorbed approximately 3.72 wt% of hydrogen, and in 20 min at 300 °C under 1 atm hydrogen pressure, it desorbed around ∼5.57 wt% of hydrogen. To ensure the cyclic stability up to 25 cycles of de/re-hydrogenation of the catalyzed MgH 2 , a continuously 25 cycles of dehydrogenation (under 1 atm hydrogen pressure at 300 °C) and rehydrogenation (under 13 atm hydrogen pressure at 300 °C) were carried out. As a result, MgH 2 -WS 2 exhibits superior cyclic stability than MgH 2 –MoS 2. In addition, with the de/re-hydrogenation kinetics, MgH 2 -WS 2 has a lower reaction activation energy (∼117 kJ/mol) than to other catalyzed and pristine samples. Conversely, the thermodynamical parameters, specifically the change in enthalpy of MgH 2 , are unaffected by addition of these layered WS 2 and MoS 2 catalysts. • The meticulous and precise synthesis of WS 2 and MoS 2 2-D nanomaterials. • The remarkable catalyst of 2-D nanomaterials for the sorption properties of MgH 2. • 2-D WS 2 and MoS 2 are exceptional catalysts in the de- and re-hydrogenation kinetics of MgH 2. • 25 cycles of dehydrogenation and rehydrogenation on WS 2 /MoS 2 -catalyzed MgH 2. [ABSTRACT FROM AUTHOR]

Previous research reported inconsistent results on the efficacy of molnupiravir in treating COVID-19. Moreover, efficacy was not assessed in the intended-use population (IUP), as defined by the FDA. Therefore, we aimed to evaluate the effectiveness and safety of molnupiravir for the treatment of COVID-19 in the IUP. We performed a retrospective cohort study on all IUP in Israel's Clalit Health Services from January 16, 2022, to February 16, 2023. The effectiveness outcome was the incidence of hospitalization or death due to COVID-19, and the safety outcome was the incidence of all-cause mortality within 35 days of SARS-CoV-2 infection. Cox-proportional hazard models were used to analyse the data after 1:5 propensity-score matching. A total of 49 515 patients met the eligibility criteria. Of them, 3957 molnupiravir-treated patients were matched to 19 785 untreated patients. In molnupiravir-treated patients, 70 out of 3957 (5.1 per 10 000 person per day) experienced COVID-19-related hospitalization or death, compared with 699 out of 19 785 untreated patients (10.4 per 10 000 person per day); RR: 0.50 (95% CI, 0.39–0.64). All-cause mortality was also lower in the treated group, with 41 out of 3957 (3.0 per 10 000 person per day) experiencing mortality compared with 414 out of 19 785 untreated patients (6.1 per 10 000 person per day); RR: 0.50 (0.36–0.68). In a real-world cohort of IUP, molnupiravir therapy was associated with a significant reduction in hospitalizations or deaths due to COVID-19 and all-cause mortality. [ABSTRACT FROM AUTHOR]

• Telemedicine offers the advantage of bridging the gap between patients in resource-limited areas and specialized care. • Various machine learning models have the potential to identify interictal biomarkers and localize seizure onset zones in patients with epilepsy. • Data bias, access to data, and integration into clinical workflows are some of the challenges facing artificial intelligence application in epilepsy care. The emergence of telemedicine and artificial intelligence (AI) has set the stage for a possible revolution in the future of medicine and neurology including the diagnosis and management of epilepsy. Telemedicine, with its proven efficacy during the COVID-19 pandemic, offers the advantage of bridging the gap between patients in resource-limited areas and specialized care, where in one study telemedicine reduced the epilepsy treatment gap from 43 % to 9 %. AI innovations promise a transformation in epilepsy care by possibly enhancing the accuracy of electroencephalogram (EEG) interpretation and seizure prediction through machine and deep learning. In one study, abnormal EEG recordings were classified into different categories using a convolutional neural networks (CNN) model showing a specificity of 90 % and an accuracy of 88.3 %. Other models constructed to predict seizures have also achieved a sensitivity of 96.8 % and specificity of 95.5 %. Various machine learning (ML) models highlight the potential AI holds in identifying interictal biomarkers and localizing seizure onset zones aiding in epilepsy treatment decision and outcome prediction. An ML model highlighted in this review localized seizure onset zone with an accuracy reaching 73 % and predicted surgical outcomes with an accuracy reaching 79 % compared to the 43 % accuracy of clinicians. However, limitations and challenges hinder the application of such technologies to reach their full potential in epilepsy care. Limitations include access to compatible devices, integration into clinical workflows, data bias, and availability of sufficient data. Extensive validated research is needed to guide future clinical practice with the implementation of technology-enhanced epilepsy care. This narrative review article will explore the use of AI and telemedicine in EEG and epilepsy care, examining their individual and combined impacts in shaping the future of epilepsy care and discussing the challenges and limitations faced in their usage. [ABSTRACT FROM AUTHOR]

To assess and compare depression, anxiety, and cognitive impairments in juvenile systemic erythematous lupus (JSLE) children with lupus nephritis (LN) during the induction and maintenance phases of treatment and to investigate the association with disease activity, damage and immunosuppressive medications. This study included 33 patients diagnosed as JSLE with LN. Attention and working memory were assessed by the working memory index Wechsler Intelligence Scale (WISC). Depression and anxiety were assessed by the Children Depression Inventory (CDI) and the Spence Children Anxiety Scale respectively. The SLE disease activity index 2000 (SLEDAI-2 K) was recorded. The mean age of the children was 11.6 ± 2.2 years, 88 % were females and 12 % males with disease duration of 16.9 ± 9.2 months and age at onset of 10.2 ± 2.3 years. Mean anxiety scores were higher among patients during the induction phase than those during maintenance phase (62.1 ± 7.2 and 40.2 ± 8.8 respectively; p < 0.001). The depression score was higher in the induction (19 ± 5.5) than in the maintenance group (12.4 ± 5.6) (p = 0.002). Mean anxiety scores significantly correlated with SLEDAI-2 K and corticosteroids dose (r = 0.58 and r = 0.43, p = 0.0004 and p = 0.013 respectively) and a significant negative correlation with duration of corticosteroids and number of cyclophosphamide doses (r = 0.46 and r = 0.69, p = 0.008 and p = 0.0001 respectively). Depression and anxiety levels were higher in children with LN during the induction phase of treatment than those in the maintenance phase. Mental health problems must be screened among children with LN and treating these problems can improve the medical and psychosocial outcomes. [ABSTRACT FROM AUTHOR]

The efficacy of whey protein supplement (WPS) in improving muscle strength, physical performance, and body composition in older adults has been widely promoted. However, the results of randomized clinical trials in this regard have been inconsistent. We aimed to determine the impact of WPS, compared to a placebo, during or without training on muscle strength, physical function, and body composition in older adults. Randomized controlled trials were thoroughly searched using PubMed, EMBASE, the Cochrane Library Database, and Scopus databases up to June 2024. The analysis focused on key parameters such as handgrip strength (HS), leg press, knee extension, gait speed (GS), 6-min walking test (6MWT), Timed-up and go test (TUG), lean body mass (LBM), fat mass (FM), and appendicular skeletal muscle mass (ASM). A pooled effect size was calculated using a random-effects model based on standardized mean differences (SMD). Thirty studies involving 2105 participants aged 60 and older met the inclusion criteria. The meta-analysis of 26 RCTs showed no significant positive effect of WPS on HS (n = 11, SMD: 0.18; 95% CI: −0.13, 0.49; I 2 = 69%), 6MWT (n = 5, SMD: −0.08; 95%CI: −0.31, 0.16; I 2 = 0%), GS test (n = 4, SMD: −0.08; 95%CI: −0.43, 0.28; I 2 = 36%), TUG test (n = 9, SMD: 0.0, 95% CI -0.15, 0.14; I 2 = 0%), LBM (n = 11, SMD: 0.02; 95%CI: −0.13, 0.17; I 2 = 0%), FM (n = 15, SMD: −0.04; 95%CI: −0.18, 0.10; I 2 = 0%). However, ASM significantly improved after WPS consumption but with high heterogeneity (n = 2, SMD: 0.39; 95%CI: 0.28, 0.51; I 2 = 69%). In interventions incorporating RE, statistically significant positive effects of WPS on lower body strength were observed (n = 11, SMD: 0.25; 95%CI: 0.05, 0.45; I 2 = 0%). The present meta-analysis indicates that WPS, when combined with resistance training (RT), can enhance lower body strength but does not seem to have a significant beneficial effect on handgrip strength, physical performance, or body composition. Further large-scale studies are necessary to confirm these findings and elucidate the potential benefits of WPS in this population. [ABSTRACT FROM AUTHOR]

Adult T-cell lymphoma/leukaemia (ATLL) is an aggressive T-cell lymphoma caused by the retrovirus HTLV-1. Its clinical presentation and course can be variable, and it may mimic other T-cell lymphomas or non-neoplastic entities. ATLL is commonly complicated by superadded Strongyloides infestation. In this setting, this can rapidly accelerate a patients demise, highlighting the need for awareness and vigilance of this dual diagnosis. [ABSTRACT FROM AUTHOR]

Cyclical vomiting syndrome (CVS) was described over 100 years ago, but it is often underdiagnosed and undertreated, even after a diagnosis is made. It is relatively common, affecting almost 2% of school-age children in some studies. Although it is traditionally seen as a childhood disease related to migraine, CVS does occur in adults. The main characteristic of CVS is the stereotypical recurrent nature of episodes of intense nausea and vomiting lasting from few hours to few days and followed by a complete resolution of symptoms. The diagnosis is predominantly a clinical one and there are internationally accepted criteria for diagnosis. The management of acute attacks of CVS aims to relieve symptoms, reduce the duration of attacks and prevent dehydration and hospital admission. Management also includes appropriate counselling on healthy lifestyle, provision of individual management plans and preventive medications. The aim of management is to reduce the number of attacks and improve quality of life. About half the children with CVS start to have migraine with or without aura in late adolescence and around 40% continue with CVS into early adult life. This article is aimed at healthcare professionals looking after children with CVS and describes the clinical presentation, the criteria required for diagnosis and outlines the different treatment options. [ABSTRACT FROM AUTHOR]

Securing computers is crucial to prevent data breaches, identity theft, and financial losses. Virus incursions disrupt operations, causing downtime and costly repairs. Protective measures, including anti-virus software and cybersecurity practices, maintain network integrity and reduce the spread of malware. Combining robust cybersecurity with green computing strategies ensures efficient energy usage and sustainable network environments, safeguarding against viruses while contributing to both security and environmental goals In this study, we explore the dynamic behaviors of a modified version of the computer virus model and elucidate the connection between its parameters and network attributes. We employ Banach's and Schaefer's fixed-point theorems to assess the existence and uniqueness of solutions of the suggested model. Furthermore, we establish sufficient conditions for Ulam–Hyers stability within the envisioned computer virus model. To analyze solution trajectories and the impact of various input factors on computer virus dynamics, we utilize an efficient numerical technique, providing insight into the relationships between model parameters and enabling the design of networks that minimize the risk of virus outbreaks under various bifurcation conditions. [ABSTRACT FROM AUTHOR]

More solid organ transplant (SOT) patients are undergoing total knee arthroplasty (TKA). This study identifies risk factors for complications, implant survivorship, and mortality in TKA patients who had prior SOT. We identified 176 TKAs in patients who had prior SOT. Of these, 77 had a prior renal (RT), 77 had a prior liver (LT) transplant, and 22 had multiple prior transplants (MT). Median survival was estimated using Kaplan-Meier. Univariate analyses were assessed with mixed-effects logistic regressions for complications and Cox-regressions for mortality. Median follow-up was 63 months (range, 24 to 109). At least one acute medical complication occurred in 25, 13, and 27% of cases with prior RT, LT, and MT, respectively (P =.12). None of the variables were significantly associated with acute medical complications. At least one surgical complication occurred in 14, 13 and 14% of cases with prior RT, LT, and MT, respectively (P = 1). Vitamin D supplementation (Odds Ratio [OR] = 0.38, P <.03) was associated with lower risk of surgical complications. Reoperation and revision rates were 5 and 3%, respectively. Older age at time of transplantation and greater level of serum creatinine at time of TKA were associated with lower risk (OR = 0.96, P =.01), and higher risk of reoperation (OR = 4.9, P =.01), respectively. Coronary artery disease was associated with higher mortality (Hazard Ratio = 2.35, P =.01). Vitamin D was associated with lower surgical complications, whereas a younger age at time of transplantation increased the risk of reoperation. Additionally, SOT patients with coronary artery disease demonstrated higher mortality after TKA. [ABSTRACT FROM AUTHOR]

To assess the amount of excess cement and the retentive strengths of two different cementation techniques (conventional cementation and practice abutment) using copings fabricated with three different cement thicknesses (20 μm, 35 μm, and 50 μm). Thirty zirconia copings were fabricated on screw retained abutments and randomly divided into three equal groups (n = 10) according to the cement thickness (20 μm, 35 μm, and 50 μm). Each group was cemented with tow cementation techniques. Cementation was performed with provisional cement (Temp-Bond). In the conventional cementation technique, cement was applied until each coping was approximately half filled, and the copings were subsequently placed on the implant–abutment assembly. Then, the copings were cleaned and cemented using the practice abutment cementation technique to remove excess cement prior to the process. Each technique was performed using copings with three different cement thicknesses (20 μm, 35 μm, and 50 μm). The specimens with the cemented copings were weighed on a high-precision analytical balance before and after removing the extruded cement, and the differences between the two measurements were calculated. Then, each specimen was subjected to a pullout test using a universal testing machine. The load required to dislodge the coping was recorded. The data were analyzed using two-way and one-way analysis of variance and independent sample t tests at a significance level of 0.05. The highest retention values were obtained for 20 μm cement thickness in the conventional technique and the practice abutment cementation technique. The amount of excess cement was the highest for the 50 μm cement thickness obtained for both cementation techniques, whereas the lowest mean values were recorded for the 20 μm cement thickness. The conventional cementation technique is recommended over the practice abutment technique to increase the retention of crowns cemented with provisional cement. However, care must be taken to remove the extruded cement. A cement thickness of 20 μm is preferable for enhancing the retention of cemented crowns and for reducing the amount of excess cement when applying both conventional and practical abutment cementation approaches. [ABSTRACT FROM AUTHOR]

Bullying in school is a universal psychosocial issue that raises concerns about adolescents' safety and mental health and is positively associated with depressive symptoms. Social support could be a preventive factor that eases bullying and its psychological distress. The primary purpose of this study was to examine the mediating effect of social support in the relationship between bullying and depressive symptoms among adolescents in Jordan. Another aim was to investigate predictors of depression based on adolescents' sociodemographic factors. In this cross-sectional, non-experimental mediational study, a stratified and systematic sampling method was used to recruit 270 Jordanian adolescents. Sociodemographic variables of being female, having divorced parents, having illiterate fathers, and being older in adolescence explained 12.2% of the variance in depressive symptoms. Family social support partially mediated the relationship between bullying and depressive symptoms. Our findings showed that a notable proportion of adolescents experienced bullying victimization and depressive symptoms, and a positive relationship exists between these two variables. These results further highlight the role of family social support in buffering the negative impact of bullying on depressive symptoms. The study's results emphasize the significance of developing and implementing family-centered social support initiatives by nurses to lessen adolescents' bullying experiences and depressive symptomatology. [ABSTRACT FROM AUTHOR]

[Display omitted] In recent times, digital technology has played a pivotal role in advancing postgraduate orthodontic education. This article comprehensively overviews digital technology's various applications, benefits, and drawbacks in postgraduate orthodontic education. Further, it examines its transformative impact on students. The primary focus of this review is on reshaping traditional teaching methods and learning experiences through innovative tools and techniques. Beginning with online learning platforms, virtual classrooms, and webinars, a comprehensive review of their role in facilitating remote education and creating interactive learning environments is provided. It also explores the integration of interactive content and multimedia in post-graduate education and emphasizes their ability to enhance students' engagement and comprehension. Augmented and virtual reality (AR/VR) technologies will also be explored, with emphasis on their role in revolutionizing practical learning experiences within postgraduate curricula. Additionally, the article discusses the part that adaptive learning and artificial intelligence (AI) play in utilizing data analytics to personalize education and optimize learning outcomes. The influence of social media platforms, mobile applications, digital libraries, and open educational resources (OER) on collaborative learning environments will be reviewed, showcasing their impact on fostering collaboration and accessibility among postgraduate students. Collaborative tools, simulations, and e-labs' role in enhancing hands-on learning experiences are highlighted. Finally, a critical analysis of the benefits and drawbacks of integrating digital technology in orthodontic education, addressing ethical and legal concerns arising from its implementation, will also be overviewed. In summary, this article explores a nuanced understanding of the transformative potential of digital technology in postgraduate orthodontic education. It encompasses various applications, benefits, challenges, and ethical considerations, guiding stakeholders toward informed integration strategies for these technologies in higher education. [ABSTRACT FROM AUTHOR]

This paper presents the process of conducting the structural analysis of AlAinSat-1 CubeSat through a numerical solution using Siemens NX. AlAinSat-1 is a 3U remote-sensing CubeSat carrying two earth observation payloads. The CubeSat is scheduled for launch on SpaceX Falcon 9 rocket. To ensure the success of the mission and its ability to withstand the launch environment, several scenarios should be analyzed. For AlAinSat-1 model the finite element analysis (FEA) method is used, and four types of structural analyses are considered: modal, quasi-static, buckling, and random vibration analyses. The workflow cycle includes idealizing, meshing, assembling, applying connections and boundary conditions, and eventually running the simulation utilizing the Siemens Nastran solver. The simulation results of all analysis types indicate that the model can safely withstand the loads exerted during launch. Also, the numerical results of the Command and Data Handling Subsystem (CDHS) module of AlAinSat-1 are experimentally validated through a vibration test conducted using an LV8 shaker system. The module successfully passed the test based on the test success criteria provided by the launcher. [ABSTRACT FROM AUTHOR]

Several international groups have published guidelines to identify low-risk breast cancer (BC) patients who are eligible for partial breast irradiation (PBI). These include the American Society for Radiation Oncology (ASTRO), the European Society for Radiotherapy and Oncology (ESTRO), and ESTRO subgroups such as the Intraoperative radiation (IORT) Task Force and Groupe Européen de Curiethérapie (GEC) -ESTRO. Only ASTRO guidelines recommend against the use of PBI in known carriers of germline pathogenic variants (PVs) in BRCA1 / 2. The aim of this study was to evaluate the proportion of BC patients, subsequently found to be BRCA1/2 PV carriers who would be eligible for PBI based on clinical-pathologic criteria of the above-mentioned international guidelines. Data were extracted from the medical records of consecutive BC BRCA1/2 PV carriers treated at a single institution between 2006 and 2023. Data included patient demographics, tumor characteristics, treatment, and disease outcomes. Overall, 498 patients with 518 primary tumors were analyzed. Of these, 282 (12 of them with synchronous bilateral disease) presented with unknown genetic status at diagnosis and formed the study cohort. The median age at diagnosis was 42.7 years (range, 23.8-77.9). Based on the recent ASTRO guidelines (not including conditionally recommended criteria), 17 of 294 (5.8%) of the carriers had tumors that would be eligible for PBI, including 3 Her2-positive tumors and 5 patients diagnosed between ages 40 and 49 years. Using the ESTRO IORT and the ACROP-ESTRO PBI criteria, 9 of 294 (3%) would be eligible, whereas with the GEC-ESTRO low-risk criteria, 31 of 294 (10.5%) of the carriers would be eligible, and their intermediate risk criteria would increase eligibility for PBI by an additional 8.2% (overall 18.7%). Using clinical-pathologic criteria published in international guidelines, 3% to 18% of BRCA1/2 PV carriers will have tumors eligible for PBI. Therefore, especially in populations who are at high risk for being BRCA1/2 PV carriers, we recommend adhering to stricter guidelines. In our cohort, ASTRO, ESTRO-IORT, and ESTRO PBI had the lowest probability of identifying BRCA1/2 PV carriers as eligible for PBI. [ABSTRACT FROM AUTHOR]

• Population-level data on the relationship between PCOS and gynecologic cancers are limited and conflicting. • We analyzed the USA-based National Inpatient Sample data over 4 years (2016–2019) • PCOS is significantly associated with higher risk of endometrial cancer. • PCOS does not associate with higher risk of ovarian and cervical cancers. This study aimed to systematically examine the relationship between polycystic ovary syndrome and ovarian, endometrial, and cervical cancers using the National Inpatient Sample (NIS) database. We utilized the International Classification of Diseases (ICD-10) system to identify relevant codes from the NIS database (2016–2019). Univariate and multivariable regression analyses (adjusted age, race, hospital region, hospital teaching status, income Zip score, smoking, alcohol use, and hormonal replacement therapy) were conducted to evaluate association between PCOS and gynecologic cancers. Results were summarized as odds ratio (OR) with 95% confidence intervals (CI). Overall, 15,024,965 patients were analyzed, of whom 56,183 and 14,968,782 patients were diagnosed with and without PCOS, respectively. Among the patients diagnosed with gynecologic cancers (n = 91,599), there were 286 with PCOS and 91,313 without PCOS. Univariate analysis revealed that PCOS was significantly associated with higher risk of endometrial cancer (OR = 1.39, 95 % CI [1.18–1.63], p < 0.0001), but lower risk of ovarian cancer (OR = 0.55, 95 % CI [0.45–0.67], p < 0.0001) and cervical cancer (OR = 0.68, 95 % CI [0.51–0.91], p = 0.009). In contrast, after Bonferroni correction, multivariable analysis depicted that PCOS remained significantly associated with higher risk of endometrial cancer (OR = 3.90, 95 % CI [4.32–4.59], p < 0.0001). There was no significant correlation between PCOS and risk of ovarian cancer (OR = 1.09, 95 % CI [0.89–1.34], p = 0.409) and cervical cancer (OR = 0.83, 95 % CI [0.62–1.11], p = 0.218). This first-ever NIS analysis showed that patients with PCOS exhibited unique gynecologic cancer risk profiles, with higher risk for endometrial cancer, and no significant risk for ovarian or cervical cancers. [ABSTRACT FROM AUTHOR]

Repeat department-wide surveys are commonly employed for infection control. There remains debate concerning their cost-effectivess. The aim of the study was to measure the impact of repeat department-wide surveys in major in-patient departments (IPDs) and ambulatory facilities (AFs) in a tertiary care hospital. This was a retrospective study of 138 surveys condcuted in 96 departments over a 5-year period. Two itemized questionnaires were designed to assess the most frequently inadequately adhered to infection control measures: one for IPD (with 21 items) and the other for AF (with 17 items). A total of 72 surveys were conducted in 49 IPDs, of which 39 (54%) were repeat surveys, and 66 surveys in 47 AFs, of which 33 (50%) were repeat surveys. The baseline rate of adherence/department was 71% ± 14 for the IPD, with an increase from the first to the last survey to 82% ± 13 (P =.037). In 15/21 measured infection control items, adherence improved. Adherence to infection control items was lower at baseline in the AFs than in the IPDs (63 ± 27), with an increase to 76 ± 20 (non significant). Although adherence improved for 9 items, it deteriorated in another 8, producing an overall statistically unchanged outcome. Repeat whole-department surveys contribute moderately to increased adherence to infection control guidelines. AFs demonstrate lower rates of adherence to infection control guidelines and are less receptive to educational measures. • Department-wide surveys (DWS) are labor intensive; are they cost-effective? • We reviewed 138 surveys in 49 in-patient departments (IPD) and 47 ambulatory units (AU). • Adherence with guidelines was 71% ± 14 per IPD and increased to 82% ± 13 (P <.05). • Adherence was lower in the AU, with an increase from 63% ± 27 per AU to 76% ± 20 (NS). • Repeat DWS contribute moderately to adherence to infection control guidelines. [ABSTRACT FROM AUTHOR]

Nurses have significant levels of depression, anxiety, and stress as a result of their exposure to various stressors at work. Emotional intelligence and resilience are relatively new notions essential for nurses to naturalize high levels of psychological problems. The study aimed to investigate the relationship between emotional intelligence and resilience and their impact on depression, anxiety, and stress among nurses. A cross-sectional descriptive design was used and recruited 152 nurses from three private hospitals in Jordan. Variables were measured using the Depression Anxiety Stress Scale, Brief Resilience Scale, and Brief Emotional Intelligence Scale. The participants' average age was 27.6 years, and they were mostly female (66.4 %). Resilience earned an average of 3.1, while emotional intelligence averaged 31.7. Depression, anxiety, and stress were all significantly higher among nurses. Also, negative relationships were found between emotional intelligence, resilience, and psychological problems (p <.001). Emotional intelligence is positively associated with resilience (r = 0.83, p <.001). In addition, emotional intelligence and resilience were both significant predictors of depression, anxiety, and stress. Emotional intelligence is critical to nurses' well-being. Higher emotional intelligence is associated with higher resilience and lower levels of depression, anxiety, and stress among nurses. Interventions and education programs emphasizing emotional intelligence and resilience are essential to improving their mental health. Healthcare organizations and governments should promote these attributes to enhance nurses' psychological wellness in challenging healthcare settings. • The study investigates emotional intelligence and resilience in Jordanian nurses. • Nurses with higher emotional intelligence display lower depression, anxiety, and stress. • Emotional intelligence and resilience exhibit a strong positive correlation. • Emotional intelligence and resilience are significant predictors of mental health outcomes. • There is an urgent need for interventions and education programs to enhance nurses' psychological well-being. [ABSTRACT FROM AUTHOR]

This systematic review was aimed to assess the prevalence of apical periodontitis (AP) in Saudi Arabia, focusing on individual-level prevalence and the frequency of AP in endodontically versus untreated teeth. This review followed the PRISMA guidelines and involved searches in several databases, including PubMed-MEDLINE, Cochrane-CENTRAL, and EMBASE, without date restrictions until August 19th, 2023. Eligibility criteria encompassed studies using CBCT, panoramic, and periapical radiographs to diagnose AP in the Saudi population. The meta -analysis employed a random-effects model due to high heterogeneity among studies. From 359 records, 13 studies were included, indicating a 40% prevalence of AP in individuals and a 6% prevalence across all teeth within the Saudi population. Root canal-treated teeth demonstrated a higher prevalence at 47%. The data revealed a substantial prevalence of AP compared to global averages, with first molars being the most affected. Studies showed moderate risk of bias and significant heterogeneity. The high occurrence of AP in Saudi Arabia, particularly in root-treated teeth, emphasizes the need for enhanced endodontic care and more accurate diagnostics. Urgent improvements in dental health policies and further research are essential to understand AP's impact and improve oral health outcomes. [ABSTRACT FROM AUTHOR]

The coronavirus (COVID-19) pandemic significantly affected health care systems worldwide, and the field of dentistry is no exception. Odontogenic infections in pediatric patients pose unique challenges to treatment and diagnosis. The purpose of this study was to evaluate the incidence, characteristics, and treatment of pediatric maxillofacial odontogenic infections during COVID-19 compared to pre-COVID-19. This retrospective cohort study included all pediatric patients (0-18 years old) who visited the emergency department (ED) at Tzafon Medical Center, Israel, between March 2020 and February 2021 (COVID-19), or between March 2018 and February 2020 (pre-COVID-19), and were diagnosed with maxillofacial odontogenic infections. Patients with missing demographic data and patients who did not complete the medical examination were excluded. The exposure variable was the date of presentation, categorized as COVID-19 or pre-COVID-19. The main outcome variables were the proportion of patients diagnosed with odontogenic infections, hospitalization rate, treatment methods, and length of hospital stay. Covariates included patient demographics, involved dentition and associated spaces, and the administration of antibiotics before ED arrival. The Fisher exact test and Pearson's χ2 test were applied to assess differences in categorical variables. The Wilcoxon rank-sum test was used for independent variables. A logistic regression model was used to predict outcome variables. P values were two-tailed, and statistical significance was defined as P <.05. The study sample comprised 471 patients: 357 (76%) in the pre-COVID-19 period and 114 (24%) during COVID-19. The relative risk of visits to the ED out of total oral and maxillofacial ED visits was lower during COVID-19 (relative risk = 0.65, P =.0001). The hospitalization rate increased from 72% (257 patients) pre-COVID-19 to 86.8% (99 patients) during the COVID-19 period (P =.001). Length of hospital stay during COVID-19 was significantly shorter than pre-COVID-19 (P <.001). The findings of this study reveal a significant reduction in odontogenic infection incidents referred to the ED during the pandemic. This implies that many of these incidents can be successfully treated in community health care settings without referral to the ED. [ABSTRACT FROM AUTHOR]

• Alveolar ridge miniscrews are an excellent choice of anchorage in an edentulous site. • Their survival rate was (62.0%) over a mean follow-up duration of 35.84 ± 19.47 months. • Clinical and demographical variables had minimal effects on their clinical efficacy. • Splinting adjacent miniscrews had a reported survival rate of 100%. An uncommon location for placing miniscrews, used to provide anchorage control in various tooth movements, is the alveolar ridge. This study aimed to provide an evaluation of the success rate of alveolar ridge miniscrews and examine variables that might impact their success. Charts for 295 patients who had miniscrews were screened. Twenty patients (5 male and 15 female: average age = 38.15 ± 15.10 years) with a total of 50 alveolar ridge miniscrews were analyzed. A customized data form was used to collect patients' and miniscrews' related variables. Kaplan–Meier estimator was used for the survival function, whereas Cox proportional hazards regression models were used to associate collected variables with alveolar ridge miniscrew survival. In total, 31 (62.0%) miniscrews were stable and 19 (38.0%) failed. The survival time for those that failed was 6.03 ± 7.08 months. The follow-up period for those that survived was 35.84 ± 19.47 months. Male gender versus female (hazard ratio [HR] 2.46; 95% confidence interval [CI] 1.35–4.48; P = 0.003), and if the miniscrew was a replacement versus non-replacement (HR 0.27; 95% CI 0.07–0.99; P = 0.048) influenced the survival. Additionally, miniscrews that were used for both indirect and direct or indirect anchorage alone plus those with evidence of splinting showed a 100% survival rate, which led to an HR 0 (P < 0.001). When the previously mentioned variables were modeled, none seemed to have a significant effect on failure except for splinting and type of anchorage (P < 0.001), because none of the splinted miniscrews failed. The failure rate of alveolar ridge miniscrews was (38.0%) over 6.03 ± 7.08 months. The survival rate was (62.0%) over 35.84 ± 19.47 months. The evidence of splinting and the type of anchorage had a significant effect on survival probability. [ABSTRACT FROM AUTHOR]

Emotions are integral to human social interactions, with diverse responses elicited by various situational contexts. Particularly, the prevalence of negative emotional states has been correlated with negative outcomes for mental health, necessitating a comprehensive analysis of their occurrence and impact on individuals. In this paper, we introduce a novel dataset named DepressionEmo designed to detect 8 emotions associated with depression by 6037 examples of long Reddit user posts. This dataset was created through a majority vote over inputs by zero-shot classifications from pre-trained models and validating the quality by annotators and ChatGPT, exhibiting an acceptable level of inter-rater reliability between annotators. The correlation between emotions, and linguistic analysis are conducted on DepressionEmo. Besides, we provide several text classification methods classified into two groups: machine learning methods such as SVM, XGBoost, and LightGBM; and deep learning methods such as BERT, BART, GAN-BERT, and T5. Despite achieving the same F1 Macro score of 0.76 as BART, the pretrained BERT model, bert-base-uncased, stands out as the most efficient model in our experiments due to its lower number of parameters. Across all emotions, the highest F1 Macro value is achieved by suicide intent, indicating a certain value of our dataset in identifying emotions in individuals with depression symptoms through text analysis. The curated dataset is publicly available at: https://github.com/abuBakarSiddiqurRahman/DepressionEmo. • Multilabel dataset creation for depression emotions • BART methods, odds ratio, population matrix and confusion matrix for analysis • Advanced LLM techniques and their comparative performance • Sentiment polarity and psycholinguistic analysis for depression emotions [ABSTRACT FROM AUTHOR]

This study evaluates the existing design methods of Geosynthetic-Reinforced Load Transfer Platform for Pile-Supported Embankments (GLTP-PSE) through comprehensive 3D Finite Element (FE) analyses. It scrutinizes the assumed arching mechanisms, methodologies, design criteria (arching height, maximum strain, differential settlement, and T in geosynthetics), and overall performance of these methods. The 3D FE analysis results and measurements from two case studies were compared with six established GLTP-PSE design methods based on the four design criteria. Key findings include the identification of a progressive concentrated ellipsoid as the developed soil arching formation, with arching height dependent on the embankment equivalent height (including embankment and traffic load), pile spacing, maximum strain along the geosynthetics, and the number of geosynthetic layers. The load distribution on geosynthetic reinforcement was observed to align more closely with a non-linear inverse triangle. These insights led to recommendations for updating existing design methods, enhancing the accuracy and reliability of GLTP-PSE designs. The study's outcomes contribute significantly to advancing and refining GLTP-PSE design practices by providing a deeper understanding of soil arching mechanisms and the performance of geosynthetic reinforcements. • Comparison of 3D FE analysis results and measurements from two case studies with six design methods with four criteria. • Identification of a progressive concentrated ellipsoid as the developed soil arching formation. • Arching height was found to be dependent on embankment equivalent, pile spacing, geosynthetics, and the geosynthetic layers. • Load distribution on geosynthetic reinforcement observed to align more closely with a non-linear inverse triangle. • Contribution to GLTP-PSE design practices by providing understanding of soil arching mechanisms and geosynthetic performance. [ABSTRACT FROM AUTHOR]

• This study delves into acute coronary syndrome recognition at triage and its effect on timely treatment. • Emergency triage pivotal in treatment delays, impacting clinical outcomes for ACS cases significantly. • Triage non-compliance leads to delays in crucial treatments, stressing accurate and timely triage importance. • Urgent need to improve triage guideline adherence, crucial for enhancing patient outcomes in emergencies. Triage nurses' pivotal role in initial assessment makes their competence crucial. However, the specific impact on Acute Coronary Syndrome (ACS) recognition and outcomes remains unclear in Jordanian healthcare. Understanding this relationship could enhance ACS management and patient outcomes in Jordanian Emergency Departments (EDs). To assess how triage nurses' recognition of ACS diagnosis affects patient outcomes in Jordan. This retrospective study examined records of 150 ACS patients admitted to the coronary care unit (CCU). Data extraction assessed triage nurses' accuracy in recognizing ACS symptoms and the timelines for diagnosis procedures (e.g., electrocardiogram [ECG]) and treatment provision (e.g., thrombolytic) based on triage decisions. It also evaluated the impact on treatment outcomes, including length of stay in the ED and hospital. Multiple linear regression analyses quantified the influence of under-triage on treatment outcomes. The sample comprised 150 patients. Most were female (78.7%), aged 45-59.9 years (37.3%). ACS classifications: unstable angina (52.0%), STEMI (38.0%), NSTEMI (10.0%). The study included a cohort of ACS patients, with findings indicating varying degrees of under-triage by triage nurses. Analysis of timelines revealed significant delays in diagnosis and treatment initiation for patients subjected to under-triage. Multiple linear regression analyses demonstrated a robust association between under-triage and prolonged time to essential treatment outcomes, including delays in physician assessment, ECG performance, thrombolytic administration, and extended ED length of stay. Triage nurses' knowledge and competency are crucial determinants of accurate ACS recognition and subsequent clinical outcomes for patients presenting to the ED in Jordan. Investing in ongoing education and training programs for triage nurses may lead to improved ACS recognition rates and better patient outcomes in Jordanian healthcare settings. [ABSTRACT FROM AUTHOR]

Secondary mitral regurgitation (MR) worsens in 10–15 % of heart failure (HF) patients receiving cardiac resynchronization therapy (CRT). Transcatheter edge-to-edge repair (TEER) with Mitra-Clip (Abbot Vascular, Santa Clara, CA, USA) therapy is associated with improved survival and decreased rates of hospitalization for HF in selected patients with secondary MR. Data on TEER outcomes in CRT-non-responders are limited. The purpose of this meta-analysis was to evaluate outcomes of mitral TEER with Mitra-Clip in CRT-non-responders. Cochrane, Scopus, MEDLINE, and EMBASE were searched for studies discussing outcomes of Mitra-Clip in CRT non-responders. Two reviewers were independently involved in screening studies and extracting relevant data. Individual study incidence rate estimates underwent logit transformation to calculate the weighted summary proportion under the random effect model. A total of eight reports met the inclusion criteria (439 patients). Mitra-Clip improved MR grade to ≤2+ in 83.8 % and 86.8 % of CRT non-responders at six months and one year, respectively. Symptomatic improvement (New York Heart Association class ≤II) was also found in 71 % and 78.1 % of CRT non-responders at six months and one year, respectively. The pooled overall incidence estimates of mortality at 30 days, 6 months, 1 year, and 2 years were 3.6 %, 9.2 %, 17.8 %, and 25.9 %, respectively. TEER with Mitra-Clip in patients with significant secondary MR who do not respond to CRT was associated with MR improvement, alleviation of symptoms, and mortality rates similar to those in the COAPT trial. [Display omitted] • Mitra-Clip improved MR in 83.8% and 86.3% of CRT non-responders at 6 and 12 months • Mitra-Clip led to New York Heart Association class ≤II in 71% and 78.1% of CRT non-responders at 6 and 12 months • Mortality benefit of Mitra-clip among CRT non-responders similar to COAPT study • CRT non-responders may benefit from Mitra-Clip if they meet COAPT anatomic criteria [ABSTRACT FROM AUTHOR]

Chronic kidney disease (CKD) affects the morphological structure and causes significant degradation in kidney function, leading to renal replacement treatment in affected individuals. Vascular rarefaction is thought to be an important factor in accelerating kidney damage in CKD patients, therefore, the assessment of renal morphology and vasculature is crucial in nephrology. The objective of this study was to evaluate the morphological and vascular changes caused by CKD in mice kidneys. In this study, dual photoacoustic microscopy (PAM) and optical coherence microscopy (OCM) oriented wide-field high-resolution imaging modalities were employed for diseased renal imaging. The unilateral ureteral obstruction (UUO) model was used to prepare renal samples with CKD, and the developed wide-field dual imaging system was used to image both control and CKD-affected kidneys for assessing vascular and morphological changes during CKD progression. The obtained results reveal a gradual alteration in vascular intensity and pelvis space with the progress of UUO disease. Furthermore, a quantitative micro-vessel analysis was performed based on the node, junction, and mesh of the vessel, which provides details on the increasing microvascular-related characteristics in the peripheral area as the disease progresses. Thus, by concurrently employing the advantages of each optical imaging technique, the proposed method of assessing the OCM-based morphological and PAM-based vascular properties of the renal sample using a wide-field multimodal imaging system can be an efficient technique for whole volume analysis without any exogenous contrast agents in kidney histopathology. [ABSTRACT FROM AUTHOR]

A one-dimensional homogeneous reactor model was developed to simulate the dynamic behavior of a fixed-bed reactor for a catalytic coupling reactor of carbon monoxide and ethyl nitrite to diethyl oxalate. Reactor modeling was performed using a comprehensive numerical model that was simulated using Simulink. The power law kinetic model was applied for simulating the catalytic coupling reaction considering the main and side reactions. The heat of reaction was calculated with respect to the reacted moles of ethyl nitrite for each reaction. When the simulated model reached a steady state, the predicted results were in agreement with the actual data that was collected from an already established pilot plant fixed bed reactor. The startup dynamic behavior of hypothetical industrial-scale production of diethyl oxalate at 78,000 tons per year was simulated. The system reached steady-state within 14–16 min at a space velocity of 1400 h−1. [ABSTRACT FROM AUTHOR]

To identify, describe and account for the incidence of spin in systematic reviews and meta-analyses of tendon transfer for the treatment of massive, irreparable rotator cuff tears. The secondary objective was to characterize the studies in which spin was identified and to determine whether identifiable patterns exist among studies with spin. This study was conducted per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Each abstract was assessed for the presence of the 15 most common types of spin derived from a previously established methodology. General data that were extracted included study title, authors, publication year, journal, level of evidence, study design, funding source, reported adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, preregistration of the study protocol, and methodologic quality per A Measurement Tool to Assess Systematic Reviews Version 2 (AMSTAR 2). The search yielded 53 articles, of which 13 were included in the final analysis. Articles were excluded if they were not published in a peer reviewed journal, not written in English, utilized cadaveric or nonhuman models, or lacked an abstract with accessible full text. 53.8% (7/13) of the included studies contained at least 1 type of spin in the abstract. Type 5 spin ("The conclusion claims beneficial effect of the experimental treatment despite a high risk of bias in primary studies") was the most common, appearing in 23.1% (3/13) of included abstracts. Nine of the spin categories did not appear in any of the included abstracts. A lower AMSTAR 2 score was significantly associated with the presence of spin in the abstract (P <.006). Spin is highly prevalent in the abstracts of systematic reviews and meta-analyses concerning tendon transfer for massive rotator cuff tears. A lower overall AMSTAR 2 rating was associated with a higher incidence of spin. Future studies should continue to explore the prevalence of spin in orthopedic literature and identify any factors that may contribute to its presence. [ABSTRACT FROM AUTHOR]

To analyze reporting bias in the form of spin present in systematic reviews and meta-analyses on the topic of primary anterior cruciate ligament (ACL) repair. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed throughout this study. Peer-reviewed systematic reviews were collected from 3 databases (PubMed, Scopus, and SPORTDiscus), and their abstracts were assessed for the 15 most common types of spin. Articles were excluded if they were not published in English, had no evidence, were retracted, were published without an abstract, did not have full text available, or included cadaveric or nonhuman subjects. Full text quality was assessed using AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews Version 2). Fisher exact tests were used to examine associations between the different types of spin and other study characteristics such as AMSTAR 2 confidence rating, study design, and level of evidence. Spin was present in the abstracts of 13 of 15 articles (86.7%). There were significant associations between PRISMA adherence and lower incidences of spin types 3, 6, and 8 (P =.029 for each). A critically low AMSTAR 2 confidence rating was significantly associated with an increased incidence of spin type 9 (P =.01), and a higher AMSTAR 2 score was significantly associated with decreased spin type 4 and type 5 (P =.039 and P =.048, respectively). A more recent year of publication was correlated with a lower incidence of spin type 14 (P =.044). Spin is present in most systematic reviews and meta-analyses regarding primary repair of the ACL, with two-thirds of abstracts spinning evidence in favor of ACL repair. Standardized guidelines including the PRISMA guidelines and the AMSTAR 2 assessment tool were negatively correlated with spin. More recently published articles were found to contain significantly less spin, as were articles published in journals with higher Clarivate Impact Factors and Scopus CiteScores. Level V, systematic review of Level III-V studies. [ABSTRACT FROM AUTHOR]

The dental adhesive market is constantly evolving to meet the demands of dentists and patients, but new products and upgrades should be rigorously evaluated before being used in clinical practice. This study investigated the physicomechanical properties and dentin bonding efficacy of a newly upgraded universal adhesive compared to its predecessor. Twenty-four molars were divided into four groups (n = 6/group) based on adhesive (new vs. predecessor) and application mode [self-etch (SE) vs. etch-and-rinse (ER)] for evaluating their dentin microtensile bond strength (μTBS), failure pattern, and bonding interface. Additional thirty-six molars' crowns were perpendicularly sectioned to obtain flat mid-coronal dentin discs. The opposing dentin surfaces of each disc received contrasting treatments (new/predecessor adhesive applied in SE/ER mode), resulting in six interventions. The bonded discs (n = 6/intervention) were used to assess the adhesives' survival probability employing a double-sided μTBS test. The other physicomechanical properties examined were adhesives' oxygen inhibition layer (OIL), viscosity, hardness, elastic modulus, degree of conversion (DC), and in-situ DC. Both adhesive versions showed similar μTBS (P > 0.05), failure pattern (P > 0.05), and survival probability (P > 0.008). ER mode promoted resin tag formation and exhibited a slender adhesive layer for both adhesives. The newer adhesive version showed a thinner adhesive layer in general with narrower OIL (P < 0.001), less viscosity (P < 0.001), higher hardness (P < 0.05), elastic modulus (P < 0.05), DC (P < 0.001), and in-situ DC (P < 0.001). While the newly updated adhesive had superior physicomechanical properties with more fluidity, its dentin bonding efficacy and survival probability were comparable to its predecessor. [ABSTRACT FROM AUTHOR]

Electrocatalysts are crucial for achieving highly efficient renewable energy conversion and storage applications. Nevertheless, doping proves to be a successful approach in creating affordable spinel oxides that exhibit exceptional electrochemical capabilities. Our study focuses on the preparation of a samarium (Sm)-doped SnFe 2 O 4 catalyst to expand the activity and stability of the oxygen evolution reaction (OER). However, the Sm-doped SnFe 2 O 4 catalyst shows a highly encouraging overpotential of 179 mV at a current density of 10 mA cm−2 and a reduced Tafel slope of 32 mA dec−1. It maintains its durability for a duration of 40 h and even after undergoing 5000th cycles. The Sm-doped SnFe 2 O 4 catalyst exhibits several positive effects, including reduced overpotential, higher catalytic current density, improved charge transfer kinetics (R ct = 0.29 Ω), and increased ECSA (111.62 cm2) value. These improved superior activity of Sm-doped SnFe 2 O 4 catalyst can be attributed to factors such as its unique interconnected structures morphology, strong synergistic effects of Sm with Sn and Fe and the robust OH− adsorption, which are more pronounced compared to the un-doped SnFe 2 O 4 , which greatly enhanced their performance in OER activity. These findings indicate that by incorporating rare earth (Sm) dopant with a high valence state, spinel oxide can be fine-tuned to potentially enhance OER optimization for energy-producing applications. [ABSTRACT FROM AUTHOR]

To investigate the incidence rate of primary brain tumors (PBTs) among Palestinian children over a 6-year interval. This study also aimed to identify the predominant histopathologic types identified in these children. This retrospective epidemiologic study focused on PBTs in children (<15 years) in Palestine. The data were collected from the registry system at Al-Makassed Hospital in Jerusalem, a prominent referral institution in Palestine and the largest center for PBTs in the region, over a 6 years period from 2018 to 2023. The incidence rate of PBTs in children (<15 years) was 1.33 per 100,000 person-years, with a 5% mortality rate. Pilocytic astrocytoma was the most common type (24%), followed by medulloblastoma (15.2%) and glioblastoma (6.3%). About one half of the tumors in children were malignant. Headaches were the most common first sign or symptom. About 20% of brain tumors in children were situated within the ventricles, making it the most prevalent location of these tumors, followed by the cerebellum (15.19%) and frontal lobe (11.39%). This is the first national study in Palestine investigating PBTs in children. The crude incidence rate of primary brain tumors among Palestinian children was lower than the incidence rate in many countries around the world. It is recommended that more research be done on the epidemiology and distribution of PBTs in children in Palestine. [ABSTRACT FROM AUTHOR]

Semna area is located within the Golden Triangle district in the Central Eastern Desert of Egypt. The study maintains using multisource datasets of remote sensing, aero-spectrometry, aero-magnetic, and field investigations for unraveling the ambiguities associated with the alteration zones at the targeted area. Three remote sensing mapping techniques including; constrained energy minimization, linear spectral unmixing, and mineral indices, were adopted to delineate the alteration zones. The γ-ray spectrometry data of K (%), K/eTh, K/eU, and F-parameter enabled mapping the potassium-enriched localities as indication on possible potassic alteration zones. The surface and subsurface linear structural features were delineated from the digital elevation model and aero-magnetic data, respectively. The outcomes of all the implemented datasets were integrated using GIS overlay modeling, producing an integrated mineralization favorability/potentiality map. Eighteen localities with high potential for mineralization were highlighted. A field study was conducted to the investigated area during which, several alteration indicators were observed, including quartz veins, iron oxides staining, kaolinite, malachite, carbonate, and muscovite (sericite) alteration indicator minerals. [ABSTRACT FROM AUTHOR]

A recent revelation has come to our attention, revealing the remarkably well-preserved post-cranial remains belonging to Protosiren. These remains include vertebrae, ribs, and fragmentary bones, and were discovered from two different horizons located in the Mokattam Formation of El-Galala Plateau, North Eastern Desert of Egypt. The first specimen, GCU0101, is identified as Protosiren sp., whereas the GCU0201 specimen is recognised as Protosiren cf. P. fraasi due to certain distinguishing features. These include vertebrae with wide keyhole-shaped neural canals, reduced tuberculum on the ribs, lack of pachyostotic ribs, and the possession of rugose articular rib head. This discovery is remarkable, as it offers a unique opportunity to study the ancient marine mammal's morphology and osteology, shedding light on its evolutionary history and ecological niche. The study documents the first occurrence of Protosiren from an ornamental limestone of the Middle Eocene (Bartonian) Observatory Formation from El-Galala Plateau, Northeastern Desert, Egypt. [ABSTRACT FROM AUTHOR]

Including pharmacists in collaborative mental healthcare models has yielded positive results. Establishing processes to enhance pharmacists' mental health care capabilities is crucial for addressing the increasing burden and improving access to mental health services. This study evaluated community pharmacists' mental health competencies and analyzed associated factors using a rigorous international framework. Additionally, it sought to identify pharmacists' training needs and support requirements as the first stop in creating a roadmap for enhancing mental healthcare through community pharmacies. A large-scale national study employing a mixed-methods approach was conducted with community pharmacists in United Arab Emirates. Semi-structured individual interviews and a cross-sectional survey were conducted. Pharmacists' core competencies were assessed using the Core Mental Health Competencies Framework for all Pharmacy Professionals. Generalized linear models were utilized to identify predictors of pharmacists' competency levels. Thematic analysis was used to analyze qualitative data. In total 650 community pharmacists completed the survey (93.7% response rate). Eight pharmacists participated in semi-structured interviews. Nearly two-thirds (63.7%) received general communication skills training, while training in motivational interviewing (44.7%), shared decision-making (37.2%), and mental illness stereotyping/stigma (23.9%) were less common. Pharmacists reported lower perceived competence in their relationship with multidisciplinary teams (M = 3.02, SD = 0.89), stigma recognition (M = 3.02, SD = 1.04), and identifying mental health crises and aiding in the person's safety (M = 3.01, SD = 1.05). Poor communication skills (p < 0.001) and working in pharmacies that do not stock psychotropic medications (p = 0.023) were associated with lower perceived competence. Qualitative analysis identified training needs in various domains, including attitudes, values, and beliefs about mental health; relationships with multidisciplinary teams; communication skills; pharmaceutical knowledge; and personal and service development. Mental health-related training is needed for community pharmacists. Addressing these needs through an intentional roadmap approach will enable pharmacists to better engage with patients with mental illness and increase access to care. [ABSTRACT FROM AUTHOR]

Metabolic and Bariatric Surgery (MBS) is the most effective management for patients with obesity and weight-related medical conditions. Nonetheless, some primary care physicians (PCPs) and surgeons from other specialties are reluctant to refer patients for MBS due to safety concerns. To compare the outcomes of patients who underwent MBS with those who underwent other common operations. American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP). Patients who underwent laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass (RYGB), classified as MBS, were compared to nine frequently performed procedures including hip arthroplasty and laparoscopic cholecystectomy, appendectomy, colectomy, hysterectomy, and hernia repairs, among others. A multivariable logistic regression was constructed to compare outcomes including readmission, reoperation, extended length of stay (ELOS) (>75th percentile or ≥3 days) and mortality. A total of 1.6 million patients were included, with 11.1% undergoing MBS. The odds of readmission were marginally lower in the cholecystectomy (adjusted odds ratio [aOR] =.88, 95% confidence interval (CI) [.85,.90]) and appendectomy (aOR =.88, 95% CI [.85,.90]) cohorts. Similarly, odds of ELOS were among the lowest, surpassed only by same-day procedures such as cholecystectomies and appendectomies. The MBS group had significantly low odds of mortality, comparable to safe anatomical procedures such as hernia repairs. Infectious and thrombotic complications were exceedingly rare and amongst the lowest after MBS. MBS demonstrates a remarkably promising safety profile and compares favorably to other common procedures in the short-term. PCPs and surgeons from other specialties can confidently refer patients for these low-risk, lifesaving operations. • Metabolic and bariatric surgery (MBS) demonstrated remarkable short-term safety. • MBS safety was comparable to many safe and common operations. • The odds of readmission, reoperation and mortality compared favorably to other operations. • Physicians should confidently refer candidate patients for these surgeries. [ABSTRACT FROM AUTHOR]

Gastric surgery is a crucial component of general surgery training. However, there is a paucity of high-quality data on operative volume and the diversity of surgical procedures that general surgery residents are exposed to. We conducted a retrospective analysis of operative case logs of all general surgery residents graduating from the American College of Graduate Medical Education–accredited program from 2009 to 2022. Data on the mean number of gastric procedures, including the mean in each subcategory, were retrieved. A Mann-Kendall trend test was used to investigate trends in operative volume. Between 2009 and 2022, the mean overall logged gastric procedures rose significantly (τ = 0.722, P <.001) from 36.2 in 2009 to 49.2 in 2022 (35.9% increase). The most substantial growth was seen in laparoscopic gastric reduction for morbid obesity (mean 1.9 in 2017 to 19 in 2022; τ = 0.670, P =.009). A statistically significant increase was also seen in laparoscopic partial gastric resections, repair of gastric perforation, and "other major stomach procedures" (P <.05 for all comparisons). Open gastrostomy, open partial gastric resections, and open vagotomy all significantly decreased (P <.05 for all comparisons). There was no significant change in the volume of laparoscopic gastrectomy, total gastric resections, and non-laparoscopic gastric reductions for morbid obesity (P >.05 for all comparisons). There has been a substantial increase in the volume of gastric surgery during residency over the past 14 years, driven mainly by an increase in laparoscopic gastric reduction. However, there may still be a need for further gastric surgical training to ensure well-rounded general surgeons. [ABSTRACT FROM AUTHOR]

• This review article focuses on the biomechanics of conventional rapid palatal expansion (RPE) and miniscrew-assisted rapid palatal expansion appliances (MARPE). • Three main things play an important role in the type of movements that follow rapid maxillary expansion: 1) Center of resistance and anatomy of maxilla, 2) Appliance system, and 3) Forces, Stress, and Strain. • The nature of forces after expansion is cyclical with force activation and decay occurring after each turn/activation of the expansion appliance. • The stress levels expressed by RPE and MARPE are different which is responsible for the difference in the effects because of RPE and MARPE • Even within MARPE, bone-anchored MARPE design and hybrid MARPE design result in different force systems or stress on the oral structures. Posterior Crossbite is a common condition resulting because of transverse maxillary deficiency. The growth of the craniofacial complex finishes first in the transverse dimension, followed by sagittal and vertical dimensions. Conventional rapid palatal expansion (RPE) appliances are commonly used to correct transverse maxillary deficiency. Although RPE is efficient in correcting posterior crossbite, it results in dental side effects such as buccal tipping of maxillary molars, root resorption, bone dehiscence, and relapse. Mini-implant-assisted RPE has been introduced to increase the skeletal effects of expansion especially in patients with increased maturation and greater interdigitation of midpalatal suture. This article will review the biomechanics of RPE and mini-implant-assisted RPE. Additionally, the different designs of MARPE and the long-term clinical effects of expansion appliances will also be discussed in detail. [ABSTRACT FROM AUTHOR]

Food waste has become a major problem in this era and is considered a waste of resources. While food waste is increasing, the energy demand is increasing as well. Producing energy from food waste can be a suitable solution for the two problems. Food waste is rich in nutrients and organic compounds. This composition makes food waste suitable to produce hydrogen. Hydrogen has attracted the attention of researchers these days because of its high ability to produce energy with no side products other than water. Food waste can be converted to hydrogen through a thermochemical process called gasification. Gasification converts biomass into a mixture of combustible gases via partial oxidation under high temperatures. In this review, different types of food waste gasification are explored. The results from recent studies are summarized in tables and compared based on the hydrogen yield and process variables. Incrementing temperature and residence time favored hydrogen production along with decrementing feed concentration. Moreover, the usage of a suitable catalyst has significantly enhanced the hydrogen production. The results have shown that food waste gasification has a promising ability to produce hydrogen, however more studies are required to investigate more on the economic feasibility of the process before commercializing it. • The potential of hydrogen production from Food Waste gasification is studied. • Studies of different food waste gasification types are investigated to demonstrate the influence of process variables. • Influence of temperature, residence time, feedstock concentration and catalyst type on hydrogen yield has been investigated. [ABSTRACT FROM AUTHOR]

The beneficial effects of orchids as a medicinal plant have been highlighted in a number of widely used medical practices. The current study has deciphered the gastro-protective effects of Acampe ochracea methanol extract (AOCE), Aerides odorata methanol extract (AOE), Cymbidium aloifolium methanol extract (CAE), and Papilionanthe teres methanol extract (PTE) in ethanol-induced ulcer. Long-Evan rats fasted; different treatment groups were administered the samples as mentioned earlier (250 and 500 mg/kg) orally; distilled water and esomeprazole (20 mg/kg p.o., b.w.) were used as normal control and standard drugs; thereafter, they received 0.5 mL of an 80 % (v/v) ethanol solution an hour later. By suppressing ulceration of the mucosal layer and altering the biochemical features of gastric juice, including the levels of carbohydrate, protein, and pepsin, the findings showed that therapy with treatments (500 mg/kg) remarkably (p < 0.001) modulated the ulcer and protected the integrity of gastric mucosa. Furthermore, treatments notably (p < 0.001, and p < 0.01) elevated the levels of the antioxidant enzymes catalase (CAT), superoxide dismutase (SOD), and reduced glutathione (GSH) and markedly (p < 0.001, and p < 0.01) decreased malondialdehyde (MDA) levels. Moreover, protecting the normal architecture of the stomach section from EtOH toxicity, the treatments unveiled notable protection from disruption of the membrane of epithelial cells and limited edema in the submucosal layer. Hence, the outcome of the investigation deciphered that the following orchids: A. ochracea, A. odorata, C. aloifolium, and P. teres might be therapeutic candidates for managing peptic ulcer disorders (PUD). [Display omitted] • Four orchid varieties were investigated for antiulcer effects. • Orchid extracts prevented ethanol-induced alcoholic ulcer generation. • Antioxidant enzymes CAT, SOD and GSH upregulated in the experimental model. • Protein and pepsin contents reflected the ulceration in the gastric mucosal layer. • Limited edema in the submucosal layer showed improvement by histopathological assay. [ABSTRACT FROM AUTHOR]

Making cheese from camel milk (CM) presents various challenges due to its different physicochemical properties compared with bovine milk (BM). In this study, we investigated the chemical composition, proteolysis, meltability, oiling off, texture profile, color, microstructure, and rheological properties of low-fat Cheddar cheese (LFCC) prepared from BM–CM blends. LFCC was produced from BM or BM supplemented with 15% CM (CM15) and 30% CM (CM30), and analyzed after 14, 60, 120, and 180 d of ripening at 8°C. Except for salt content, no significant differences were observed among LFCC from BM, CM15, and CM30. The addition of CM increased the meltability and oiling off in the resulting cheese throughout storage. With respect to color properties, after melting, LFCC CM30 showed lower L* values than LFCC made from BM and CM15, and a* and b* values were higher than those of BM and CM15 samples. LFCC from CM30 also exhibited lower hardness compared with the other cheeses. Moreover, LFCC made from BM showed a rough granular surface, but cheese samples made from BM–CM blends exhibited a smooth surface. The rheological parameters, including storage modulus, loss modulus, and loss tangent, varied among cheese treatments. The determined acetoin and short-chain volatile acids (C2–C6) in LFCC were affected by the use of CM, because CM15 showed significantly higher amounts than BM and CM30, respectively. The detailed interactions between BM and CM in the cheese matrix should be further investigated. [ABSTRACT FROM AUTHOR]

Dorsal seroma is a common complication of autologous latissimus dorsi flap (ALDF) in breast reconstruction, and has limited the use of this technique, despite its aesthetic success. It is important to find a right technique to limit the incidence of seroma formation after ALDF. The aim of this study was to evaluate the effectiveness and tolerance of a dorsal quilting technique called "running quilting" using barbed resorbable suture in seroma prevention. Three hundred patients who underwent ALDF breast reconstruction in the period between 2004 and 2014 were included in this study. The population was divided in 3 groups; without quilting, with simple quilting suture, and with running quilting using barbed suture. The incidence of small seromas (requiring 1 or 2 aspirations during routine postoperative visits without adding additional appointments to the follow-up routine) was not significantly decreased: it was 54% in the non-quilted group, 47% in group 2 Quilting, and 34% in group 3 running quilting. However, quilting reduced the duration of drainage, and the rate of late seromas (from 8% to 0%), and chronic sero-hematomas completely disappeared in our experience. Running quilting using barbed suture is highly effective in preventing late and refractory donor-site seromas. Its effectiveness is expected to increase the use of ALDF in breast reconstruction, which we consider currently as one of the best autologous reconstruction techniques. [ABSTRACT FROM AUTHOR]

There is a lack of consensus on the definition of upfront resectability and use of perioperative systemic therapy for colorectal liver metastases (CRLM). This survey aimed to summarize the current treatment strategies for upfront resectable CRLM throughout Europe. A survey was sent to all members of the European-African Hepato-Pancreato-Biliary Association to gain insight into the current views on resectability and the use of systemic therapy for upfront resectable CRLM. The survey was completed by 87 surgeons from 24 countries. The resectability of CRLM is mostly based on the volume of the future liver remnant, while considering tumor biology. Thermal ablation was considered as an acceptable adjunct to resection in parenchymal-sparing CRLM surgery by 77 % of the respondents. A total of 40.2 % of the respondents preferred standard perioperative systemic therapy and 24.1 % preferred standard upfront local treatment. Among the participating European hepato-pancreato-biliary surgeons, there is a high degree of consensus on the definition of CRLM resectability. However, there is much variety in the use of adjunctive thermal ablation. Major variations persist in the use of perioperative systemic therapy in cases of upfront resectable CRLM, stressing the need for further evidence and a consensus. [ABSTRACT FROM AUTHOR]