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• A multi-type lesion detection method based on white light endoscopy is proposed. • Combined with image characteristics, optimize data preprocessing operations. • The method can be applied to colorectal data sets based on white light endoscopy. • In the case study, the proposed method performed the best. White-light endoscopy is an effective means of detecting colorectal lesions. Aiming at the phenomenon of misdetection and missed detection that are prone to occur in the detection process, this paper proposes an improved YOLOv7 model (CSS-YOLOv7) for lesion classification detection. First of all, the CNeB module is used to replace part of the ELAN module of the backbone and neck network, which can extract the features of the lesion area, reduce the number of network layers and model parameters, and improve the training speed. Second, colorectal lesion maps generated by white-light endoscopy have low resolution. Therefore, in response to this drawback, this study added the SPD-Conv module to the original model to effectively prevent fine-grained damage that may be caused by strided convolution. Finally, the SIOU loss function is used to enable the prediction frame to converge faster, and the precision and efficiency are effectively improved. The experimental results show that the recall rate of the model proposed in this paper is 92.3%, and mAP@.5 reaches 95.9%, which can promote the development of automatic detection of colorectal lesions. [ABSTRACT FROM AUTHOR]

Bedded barite deposits are found in Cambrian and Devonian strata in China. In this paper, we report the occurrence of Late Paleozoic methane seeps from bedded barite in one of the largest barite deposits in China. The ore bodies are stratiform and lenticular in shape and are hosted within Upper Devonian cherts. The barite deposits usually have laminar, banded, fragmental, massive and rosette textures, and radial and spheroidal structures were observed in the barite ores. Nodular limestones are associated with the barite deposits; they consist of clotted micrites and framboidal pyrites. The internal structure of framboidal pyrite is simple, in which the sun-flower structure has been observed, similar to modern seep carbonates. The δ 13 C V-PDB values range from − 8.82‰ to − 10.27‰, and δ 18 O V-PDB ranges from − 8.10‰ to − 8.20‰ in Xiyahe and from + 0.03‰ to − 3.31‰ in Luocheng. The 13 C depletion suggests that these carbonates formed in a methane seep through the anaerobic oxidation of methane (AOM). This evidence lends strong support to the interpretation that methane hydrate contributed to the barite deposition. In addition, the δ 13 C V-PDB values decrease gradually from Xiyahe to Luocheng, which indicates the gradually weakening strength of the methane seep activities. The δ 30 Si NBS-28 values of the cherts range from − 0.3‰ to + 0.5‰, except for two samples (LJ-24: δ 30 Si NBS-28 values = + 0.9‰; ZL18: δ 30 Si NBS-28 values = + 1.1‰). The lowest δ 30 Si NBS-28 values reflect silicon derived from hydrothermal fluids ascribed to intense tectonic activity, which consequently caused the rapid maturity of hydrocarbons. The 87 Sr/ 86 Sr values ( 87 Sr/ 86 Sr = 0.70863–0.70898, avg. 0.70877; n = 11) of barite are higher than the average value of contemporary seawater, showing that hydrothermal processes played a minor role in barite mineralization. [ABSTRACT FROM AUTHOR]

A period-eight cycle route to chaos has been observed in a stimulated Brillouin scattering (SBS) system for the first time. Since the observation of fine periodic-orbit structure in very short dynamical region of chaotic domain is very difficult, in this work, we design a novel experiment to extend the chaotic domain by injecting light to the end of fiber and adjusting the proportion of stimulated Brillouin backscattering power and pump power, the present result shows the period-eight cycle route to chaotic laser process as well as more details of chaos. Simulations of the route to chaos are also presented. [ABSTRACT FROM AUTHOR]

This paper draws upon smart growth theory to provide an analytical framework of "smart identification" for industrial land to be readjusted. Huai'an city, Jiangsu province, China, is selected as a case example for the developed framework. Unlike the identification method of efficiency orientation for stock industrial land, which emphasizes the core goal of input and output of production factors per unit area, the smart identification framework covers the five dimensions of industrial policy, urban planning, socioeconomic benefits, transportation convenience, and environment protection. The framework pays more attention to the characteristics of high-quality socioeconomic development, including innovation-driven, coordinated, and sustainable development. Industrial land blocks are used as the research unit. A total of 1,552 industrial land blocks are identified for readjustment, covering an area of 4,008.7 hm2 and accounting for 54.3% of the total industrial land area in Huai'an city; this shows that considerable potential exists for adjustment. We argue that the evaluation index selection of intensive industrial land use and the method by which industrial land is identified for readjustment is influenced by the stage of socioeconomic development. The smart identification method is more consistent with the connotation of high-quality development, and more conducive to revealing the current demand and change law of industrial land against the background of industrial transformation and upgrading, which is of great significance with regard to promoting the intensive use and spatial optimization of industrial land. [ABSTRACT FROM AUTHOR]

[Display omitted] • Distinct Δ199Hg values of several tuff layers suggest that their magma sources can be different. • Volcanisms triggered the Late Ordovician and end-Guadalupian mass extinctions. • Hg isotopes as a useful proxy in revealing the type of volcanism in geological history. Mercury (Hg) anomalies in sedimentary records are a newly developed proxy of large volcanism in the geological past. Tuff layers host abundant volcanic ash and record key information on the type of volcanic emission (e.g., arc volcanism and large igneous province eruptions). Here, we measured the Hg isotopic compositions of several tuff layers in South China. Tuff samples in the Late Ordovician Wufeng Formation and the Middle Triassic Guanling Formation mostly show positive Δ199Hg values of – 0.01 to 0.10‰ and – 0.06 to 0.16‰, respectively, suggesting arc volcanism occurred during these two periods. Tuff samples in the Middle Permian Dachang Layer mostly show near-zero Δ199Hg values (– 0.08 to 0.00‰), suggesting volcanism was driven by the Emeishan large igneous province eruption. Results of this study verify Hg isotopes as a useful proxy in revealing the type of volcanism in geological history. [ABSTRACT FROM AUTHOR]

Cirsitakaoside is a natural compound isolated from Premna szemaoensis . However, the anti-inflammatory effects of cirsitakaoside are poorly understood. We investigated the anti-inflammatory action of cirsitakaoside in lipopolysaccharide (LPS)-stimulated macrophages and mice in vivo. Cirsitakaoside could suppress the production of pro-inflammatory cytokines such as interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) in a dose-dependent manner in LPS-stimulated mouse peritoneal macrophages and RAW264.7 cells. Cirsitakaoside also could inhibit inducible nitric oxide synthase (iNOS) mRNA and cyclooxygenase-2 (COX-2) mRNA expression in LPS-stimulated mouse peritoneal macrophages and RAW264.7 cells. These effects were partially carried out by inactivated nuclear factor-κB (NF-κB) and Mitogen-activated protein kinases (MAPKs) pathway via inhibiting the phosphorylation of the IKKα/β, IκBα and c-Jun N-terminal kinase/stress-activated protein kinase (JNK) in LPS-stimulated murine macrophages. In vivo, we showed that cirsitakaoside could relieve LPS-induced inflammation response. These results suggest that cirsitakaoside has the potential anti-inflammatory effect for treatment of inflammation diseases. [ABSTRACT FROM AUTHOR]

Abstract: Single-walled carbon nanotubes (SWNTs) were dispersed in the form of individual nanotubes and small bundles, and subsequently polymerized to prepare composite films. The nanotubes were first dispersed in dimethylacetamide in the presence of 1,3-bis(3-aminophenoxy)benzene (APB), which was then polymerized with 4,4′-hexafluoroisopropylidiene diphthalic anhydride (6-FDA). Optical microscopy, SEM and TEM studies of the composite show that the SWNTs are homogenously distributed in the polymer matrix, and AFM observations indicate that ∼80% of the dispersed SWNTs are stabilized as individual nanotubes. The freestanding composite films were found to have very good optical, thermal and mechanical properties as well as enhanced electrostatic charge dissipation properties. [Copyright &y& Elsevier]