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Start Over Author "Sykes, Hannah E." Publisher elsevier b.v.
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1. Fluorogenic 7-azidocoumarin and 3/4-azidophthalimide derivatives as indicators of reductase activity in microorganisms.

Author

Chalansonnet, Valerie, Lowe, John, Orenga, Sylvain, Perry, John D., Robinson, Shaun N., Stanforth, Stephen P., Sykes, Hannah E., and Truong, Thang V.

Subjects
*HYDROGEN sulfide, *MICROORGANISMS
Abstract

A series of fluorogenic heterocyclic azides were prepared and assessed as reductase substrates across a selection of Gram-negative and Gram-positive microorganisms. The majority of these azides showed similar activity profiles to nitroreductase substrates. Microorganisms that do not produce hydrogen sulfide reduced the azides, indicating reductase activity was not linked to hydrogen sulfide production. [ABSTRACT FROM AUTHOR]

Published
2019
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