1. Immunomodulators in the Treatment of Nasal Polyposis.
- Author
-
Halderman AA and Lane AP
- Subjects
- Chronic Disease, Humans, Rhinitis drug therapy, Sinusitis drug therapy, Immunologic Factors therapeutic use, Nasal Polyps drug therapy
- Abstract
The inflammatory mechanisms that contribute to chronic rhinosinusitis with nasal polyps (CRSwNP) are complex. In the past, medical options for treating CRSwNP have been limited. Emerging classes of immunomodulators such as omalizumab, anti-leukotrienes, anti-IL-4, anti-IL-5, and recognition of the modulating effects of macrolides have shown promising results in the treatment of CRSwNP. Ultimately, large randomized controlled trials are necessary to establish the efficacy of these medications but for now, the area of medical immunomodulators remains an exciting frontier., (© 2016 S. Karger AG, Basel.)
- Published
- 2016
- Full Text
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