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Your search keyword '"Germano, Paola"' showing total 5 results
Start Over Author "Germano, Paola" Publisher lippincott williams & wilkins
5 results on '"Germano, Paola"'

4. Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters.

Author

Baroncelli S, Ricci E, Andreotti M, Guidotti G, Germano P, Marazzi MC, Vella S, Palombi L, De Rossi A, and Giuliano M

Subjects
Antiretroviral Therapy, Highly Active, Female, Genetic Predisposition to Disease, HIV Infections drug therapy, HIV Infections virology, Humans, Milk, Human virology, RNA, Viral analysis, Viral Load, HIV Infections genetics, HIV-1 isolation & purification, Polymorphism, Single Nucleotide, beta-Defensins genetics
Abstract

We analyzed single nucleotide polymorphisms in the 5'-untranslated region (-44C/G and -52G/A) of the beta-defensin-1 gene in 78 Mozambican HIV-1-infected mothers. We observed significantly lower levels of HIV-1 RNA in breast milk, but not in plasma, in women with the -52GG genotype versus women with the -52GA and -52AA genotypes, supporting the hypothesis that different expression of beta-defensins could have an impact on viral replication in breast milk.

Published
2008
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5. Resistance mutation patterns in plasma and breast milk of HIV-infected women receiving highly-active antiretroviral therapy for mother-to-child transmission prevention.

Author

Andreotti M, Guidotti G, Galluzzo CM, Mancinelli S, Germano P, Pirillo MF, Marazzi MC, Vella S, Palombi L, and Giuliano M

Subjects
Antiretroviral Therapy, Highly Active, Female, HIV Infections prevention & control, HIV Infections virology, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical prevention & control, Milk, Human virology, RNA, Viral analysis, RNA, Viral blood, Anti-HIV Agents therapeutic use, Genes, MDR, HIV Infections drug therapy, HIV-1 genetics, Mutation
Published
2007
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