Search

Hydrogel-based flexible electronic devices have great potential in human motion monitoring, electronic skins, and human-computer interaction applications; hence, the efficient preparation of highly sensitive hydrogel-based flexible sensors is important. In the present work, the ultrafast polymerization of a hydrogel (1–3 min) was achieved by constructing a tannic acid (TA)-Fe3+ dynamic redox system, which endowed the hydrogel with good adhesion performance (the adhesion strength in wood was 17.646 kPa). In addition, the uniform dispersal ensured by incorporating polydopamine-decorated polypyrrole (PPy@PDA) into the hydrogel matrix significantly improved the hydrogel's stretching ability (575.082%). The as-prepared PAM/CS/PPy@PDA/TA hydrogel-based flexible sensor had a high-fidelity low detection limit (strain = 1%), high sensitivity at small strains (GF = 5.311 at strain = 0–8%), and fast response time (0.33 s) and recovery time (0.25 s), and it was reliably applied to accurate human motion monitoring and handwriting recognition. The PAM/CS/PPy@PDA/TA hydrogel opens new horizons for wearable electronic devices, electronic skins, and human-computer interaction applications. [ABSTRACT FROM AUTHOR]

A periodic intermittent adaptive control method with saturation is proposed to pin the quasi-consensus of nonlinear heterogeneous multi-agent systems with external disturbances in this paper. A new periodic intermittent adaptive control protocol with saturation is designed to control the internal coupling between the follower agents and the feedback gain between the leader and the follower. In particular, we use the saturation adaptive law: when the quasi-consensus error converges to a certain range, the adaptive coupling edge weight and the adaptive feedback gain will not be updated. Furthermore, we propose three saturated adaptive pinning control protocols. The quasi-consensus is achieved through its own pinning as long as the agents remain connected to each other. Using the Lyapunov function method and inequality technique, the convergence range of the quasi-consensus error of a heterogeneous multi-agent system is obtained. Finally, the rationality of the proposed control protocol is verified through numerical simulation. Theoretical derivation and simulation results show that the novel proposed periodic intermittent adaptive control method with saturation can successfully be used to achieve the pinning of quasi-consensus of nonlinear heterogeneous multi-agent systems. [ABSTRACT FROM AUTHOR]

Organic-inorganic halide perovskite solar cells (PSCs) have attracted much attention in recent years due to their simple manufacturing process, low cost, and high efficiency. So far, all efficient organic-inorganic halide PSCs are mainly made of polycrystalline perovskite films. There are transmission barriers and high-density defects on the surface, interface, and grain boundary of the films. Among them, the deep-level traps caused by specific charged defects are the main non-radiative recombination centers, which is the most important factor in limiting the photoelectric conversion efficiency of PSCs devices to the Shockley-Queisser (S-Q) theoretical efficiency limit. Therefore, it is imperative to select appropriate passivation materials and passivation strategies to effectively eliminate defects in perovskite films to improve their photovoltaic performance and stability. There are various passivation strategies for different components of PSCs, including interface engineering, additive engineering, antisolvent engineering, dopant engineering, etc. In this review, we summarize a large number of defect passivation work to illustrate the latest progress of different types of passivators in regulating the morphology, grain boundary, grain size, charge recombination, and defect density of states of perovskite films. In addition, we discuss the inherent defects of key materials in carrier transporting layers and the corresponding passivation strategies to further optimize PSCs components. Finally, some perspectives on the opportunities and challenges of PSCs in future development are highlighted. [ABSTRACT FROM AUTHOR]

River discharge monitoring is an important component of the hydrology objectives of Surface Water and Ocean Topography mission (SWOT). River discharge can be estimated Solely using river widths and At Many-stations Hydraulic Geometry (AMHG), but the accuracy is low due to the parameters of At a-station Hydraulic Geometry (AHG) given by AMHG deviate from the truth. In view of this, a Constrained At-Many-Stations Hydraulic Geometry (CAMHG) is proposed to optimize AHG parameters. The performance of CAMHG is verified in three reaches of the Yangtze River using river widths derived from SWOT. After using CAMHG, the relative root mean square error (RRMSE) of estimated discharge reduce 100.1% to 24.4%, 1137.1% to 49.9% and 48.6% to 45.5% for Hankou, Shashi and Luoshan respectively. In addition, CAMHG can also weaken the accuracy difference of estimated discharge in dry and wet seasons benefited from its more reliable AHG parameters. Thus, the proposed CAMHG can dramatically improves the accuracy of discharge estimations and it is meaningful for the discharge calculation after SWOT data release. [ABSTRACT FROM AUTHOR]

In this paper, a core-shell based on the Fe3O4@SiO2@Au nanoparticle amplification technique for a surface plasmon resonance (SPR) sensor is proposed. Fe3O4@SiO2@AuNPs were used not only to amplify SPR signals, but also to rapidly separate and enrich T-2 toxin via an external magnetic field. We detected T-2 toxin using the direct competition method in order to evaluate the amplification effect of Fe3O4@SiO2@AuNPs. A T-2 toxin–protein conjugate (T2-OVA) immobilized on the surface of 3-mercaptopropionic acid-modified sensing film competed with T-2 toxin to combine with the T-2 toxin antibody–Fe3O4@SiO2@AuNPs conjugates (mAb-Fe3O4@SiO2@AuNPs) as signal amplification elements. With the decrease in T-2 toxin concentration, the SPR signal gradually increased. In other words, the SPR response was inversely proportional to T-2 toxin. The results showed that there was a good linear relationship in the range of 1 ng/mL~100 ng/mL, and the limit of detection was 0.57 ng/mL. This work also provides a new possibility to improve the sensitivity of SPR biosensors in the detection of small molecules and in disease diagnosis. [ABSTRACT FROM AUTHOR]

In wheat production, improving resource utilization and grain yield is the goal researcher have been pursuing. This study aimed to investigate if a regulated nitrogen (N) and selenium (Se) fertilizer management could increase wheat yield and N use efficiency (NUE). This study reports the effects of three N application levels (N0: 0 kg N ha−1, N1: 180 kg N ha−1, N2: 270 kg N ha−1) and a combination of three Se application levels (Se0: 0 g Se ha−1, Se1: 450 g Se ha−1, Se2: 900 g Se ha−1) on N metabolism, NUE and yield in wheat in 2020–2021. Compared with N0, wheat yield increased by 44.76% in N1 and by 54.32% in N2, and the activity of N-metabolizing enzymes increased by 25.15~35.03% in N1 and by 32.01~51.27% in N2. Compared with N1, the apparent recovery efficiency of N, the agronomic N use efficiency and the partial factor productivity of applied N decreased by 15.71%, 28.00% and 28.93% in N2, respectively. Compared with Se0, the 1000-grain weight increased by 3.93% in Se1 and by 4.87% in Se2, and the activity of nitrogen-metabolizing enzymes increased by 4.23~4.91% in Se1 and by 6.65~8.46% in Se2. We conclude that Se could improve the wheat 1000-grain weigh and N metabolism and has the potential to increase wheat yield and NUE. [ABSTRACT FROM AUTHOR]

The present work is conducted to investigate the optimal extraction technology of polysaccharide from chestnut mushroom (Agrocybe aegerita) using a new method based on accelerated solvent extraction combined with response surface methodology (ASE-RSM). The conventional reflux extraction (CRE) method and ultrasonic-assisted extraction (UAE) method were also carried out. Additionally, the in vitro antioxidant activities, including ABTS and DPPH assay, were evaluated. The RSM method, based on a three level and three variable Box–Behnken design (BBD), was developed to obtain the optimal combination of extraction conditions. In brief, the polysaccharide was optimally extracted with water as extraction solvent, extraction temperature of 71 °C, extraction time of 6.5 min, number of cycles of 3, and extraction pressure of 10 MPa. The 3D response surface plot and the contour plot derived from the mathematical models were applied to determine the optimal conditions. Under the above conditions, the experimental value of polysaccharide yield was 19.77 ± 0.12%, which is in close agreement with the value (19.81%) predicted by the model. These findings demonstrate that ASE-RSM produce much higher polysaccharide and consumed environmentally friendly extraction and solvent systems, have less extraction discrimination and shorter time and provide scientific basis for industrialization of polysaccharide extraction. Moreover, it was proved that the polysaccharide had the potential ability to scavenge ABTS and DPPH. [ABSTRACT FROM AUTHOR]

Some photosensitive resins have poor mechanical properties after 3D printing. To overcome these limitations, a polyurethane acrylate oligomer (PUA) microsphere was prepared using the Pickering emulsion template method and ultraviolet (UV) curing technology in this paper. The prepared PUA microspheres were added to PUA-1,6-hexanediol diacrylate (HDDA) photosensitive resin system for digital light processing (DLP) 3D printing technology. The preparation process of PUA microspheres was discussed based on micromorphology, and it was found that the oil-water ratio of the Pickering emulsion and the emulsification speed had a certain effect on the microsphere size. As the oil-water ratio and the emulsification speed increased, the microsphere particle size decreased to a certain extent. Adding a suitable proportion of PUA microspheres to the photosensitive resin can improve the mechanical properties and thermal stability. When the modified photosensitive resin microsphere content was 0.5%, the tensile strength, elongation at break, bending strength, and initial thermal decomposition temperature were increased by 79.14%, 47.26%, 26.69%, and 10.65%, respectively, compared with the unmodified photosensitive resin. This study provides a new way to improve the mechanical properties of photosensitive resin 3D printing. The resin materials studied in this work have potential application value in the fields of ceramic 3D printing and dental temporary replacement materials. [ABSTRACT FROM AUTHOR]

The mechanical properties and microstructure of the cemented paste backfill (CPB) in dry–wet cycle environments are particularly critical in backfill mining. In this study, coal gangue, fly ash, cement, glass fiber, and nano-SiO2 were used to prepare CPB, and dry–wet cycle tests on CPB specimens with different curing ages were conducted. The compressive, tensile, and shear strength of CPB specimens with different curing ages under different dry–wet cycles were analyzed, and the microstructural damage of the specimens was observed by scanning electron microscopy (SEM). The results show that compared with the specimens without dry–wet cycles, the uniaxial compressive strength, tensile strength, and shear strength of the specimens with a curing age of 7 d after seven dry–wet cycles were the smallest, being reduced by 40.22%, 58.25%, and 66.8%, respectively. After seven dry–wet cycles, the compressive, tensile, and shear strength of the specimens with the curing age of 28 d decreased slightly. The SEM results show that with the increasing number of dry–wet cycles, the internal structure of the specimen becomes more and more loose and fragile, and the damage degree of the structural skeleton gradually increases, leading to the poor mechanical properties of CPB specimens. The number of cracks and pores on the specimen surface is relatively limited after a curing age of 28 d, while the occurrence of internal structural damage within the specimen remains insignificant. Therefore, the dry–wet cycle has an important influence on the both mechanical properties and microstructure of CPB. This study provides a reference for the treatment of coal-based solid waste and facilitates the understanding of the mechanical properties of backfill materials under dry–wet cycling conditions. [ABSTRACT FROM AUTHOR]

Anthocyanin is a type of flavonoid pigment widely present in fruits and vegetables. It can not only be used as natural pigment, but also has a variety of health functions, for instance, anti-oxidant, anti-inflammatory, anti-tumor, and neuroprotective activities. Persistent proinflammatory status is a major factor in the development, progression, and complications of chronic diseases. Not surprisingly, there are thus many food ingredients that can potentially affect inflammation related diseases and many studies have shown that anthocyanins play an important role in inflammatory pathways. In this paper, the inflammation related diseases (such as, obesity, diabetes, cardiovascular disease, and cancer) of anthocyanins are introduced, and the anti-inflammatory effect of anthocyanins is emphatically introduced. Moreover, the anti-inflammatory mechanism of anthocyanins is elaborated from the aspects of NF-κB, toll like receptor, MAPKs, NO, and ROS and the main efficacy of anthocyanins in inflammation and related diseases is determined. In conclusion, this review aims to get a clear insight into the role of anthocyanins in inflammation related diseases. [ABSTRACT FROM AUTHOR]

This paper systematically studies the effect of Fe3O4 nanoparticle size on the insulation performance of nanofluid impregnated paper. Three kinds of Fe3O4 nanoparticles with different sizes and their nanofluid impregnated papers were prepared. Environmental scanning electron microscopy (ESEM) and infrared spectroscopy were used to analyze the combination of Fe3O4 nanoparticles and nanofluid impregnated paper. The effect of nanoparticle size on breakdown voltage and several dielectric characteristics, e.g., permittivity, dielectric loss, of the nanofluid impregnated paper were comparatively investigated. Studies show that the Fe3O4 nanoparticles were bound to impregnated paper fibers by O–H bonds, while the relative permittivity and dielectric loss of the nanofluid impregnated papers were increased. Meanwhile, the increase of trap depth, caused by the nanoparticles, can trap the electric charge and improve the breakdown strength. The test results show that the direct current (DC) and alternating current (AC) breakdown voltages of nanofluid impregnated paper increased by 9.1% and 10.0% compared to FR3 nanofluid impregnated paper, respectively. [ABSTRACT FROM AUTHOR]

An optical waveguide (OWG) sensor was developed for real-time detection of diethyl chlorophosphate (DCP) vapor, which is a typical simulant for organophosphorus pesticides and chemical weapon agents. Silica gel, crystal violet (CV), and potassium ion-exchange (PIE) OWG were used to fabricate the sensor's device. In the real-time detection of the DCP vapor, the volume fraction of DCP vapor was recorded to be as low as 1.68 × 10−9. Moreover, the detection mechanism of CV-SiO2 gel film coated the PIE OWG sensor for DCP, which was evaluated by absorption spectra. These results demonstrated that the change of output light intensity of the OWG sensor significantly increased with the augment of the DCP concentration. Repeatability as well as selectivity of the sensors were tested using 0.042 × 10−6 and 26.32 × 10−6 volume fraction of the DCP vapor. No clear interference with the DCP detection was observed in the presence of other common solvents (e.g., acetone, methanol, dichloromethane, dimethylsulfoxide, and tetrahydrofuran), benzene series (e.g., benzene, toluene, chlorobenzene, and aniline), phosphorus-containing reagents (e.g., dimethyl methylphosphonate and trimethyl phosphate), acid, and basic gas (e.g., acetic acid and 25% ammonium hydroxide), which demonstrates that the OWG sensor could provide real-time, fast, and accurate measurement results for the detection of DCP. [ABSTRACT FROM AUTHOR]

β-glucan is a non-starch soluble polysaccharide widely present in yeast, mushrooms, bacteria, algae, barley, and oat. β-Glucan is regarded as a functional food ingredient due to its various health benefits. The high molecular weight (Mw) and high viscosity of β-glucan are responsible for its hypocholesterolemic and hypoglycemic properties. Thus, β-glucan is also used in the food industry for the production of functional food products. The inherent gel-forming property and high viscosity of β-glucan lead to the production of low-fat foods with improved textural properties. Various studies have reported the relationship between the molecular structure of β-glucan and its functionality. The structural characteristics of β-glucan, including specific glycosidic linkages, monosaccharide compositions, Mw, and chain conformation, were reported to affect its physiochemical and biological properties. Researchers have also reported some chemical, physical, and enzymatic treatments can successfully alter the molecular structure and functionalities of β-glucan. This review article attempts to review the available literature on the relationship of the molecular structure of β-glucan with its functionalities, and future perspectives in this area. [ABSTRACT FROM AUTHOR]

Rapid and accurate detection of protein toxins is crucial for public health. The Raman spectra of several protein toxins, such as abrin, ricin, staphylococcal enterotoxin B (SEB), and bungarotoxin (BGT), have been studied. Multivariate scattering correction (MSC), Savitzky–Golay smoothing (SG), and wavelet transform methods (WT) were applied to preprocess Raman spectra. A principal component analysis (PCA) was used to extract spectral features, and the PCA score plots clustered four toxins with two other proteins. The k-means clustering results show that the spectra processed with MSC and MSC-SG methods have the best classification performance. Then, the two data types were classified using partial least squares discriminant analysis (PLS-DA) with an accuracy of 100%. The prediction results of the PCA and PLS-DA and the partial least squares regression model (PLSR) perform well for the fingerprint region spectra. The PLSR model demonstrates excellent classification and regression ability (accuracy = 100%, Rcv = 0.776). Four toxins were correctly classified with interference from two proteins. Classification models based on spectral feature extraction were established. This strategy shows excellent potential in toxin detection and public health protection. These models provide alternative paths for the development of rapid detection devices. [ABSTRACT FROM AUTHOR]

This study explored the effects of the sowing stage and nitrogen application rate on the grain yield and its allocation of light-temperature resources over a 9-year experiment from 2011 to 2019. Measurement indicators include the effective accumulative temperature on different growth durations, leaf area index (LAI), above-ground biomass production, and harvest index (HI). Methods: A split-plot design was arranged in the treatment, with N supply as the main plot and the sowing stage as the subplot. The main plots consisted of two nitrogen treatments: low nitrogen (LN: 120 kg ha−1) and high nitrogen (HN: 180 kg ha−1). The subplots contained two sowing stages: the early sowing stage (ES) and the late sowing stage (LS). Results: Compared with LNLS, LNES, and HNLS from 2011 to 2019, HNES of HHZ increased the grain yield by 9.5%, 2.5%, and 5.3%, while the difference in grain yield in YY8 was higher than HHZ, especially under HNES. Compared with LNLS, LNES, and HNLS from 2011 to 2019, HNES of HHZ increased the panicle number by 6.0%, 5.9%, and 1.0%, and HNES of YY8 increased by 12.7%, 11.4%, and 3.8%. Compared with HNLS of HHZ, LNES, LNLS, and HNES decreased the spikelets per panicle by 2.3%, 2.9%, and 1.1%, and decreased by 3.5%, 1.9%, and 2.2% in YY8. The early sowing or increasing N supply significantly increased the dry matter accumulated, grain weight, LAI, and HI. The higher grain yield in LNES was more closely related to the average temperature and the number of spikelets per panicle. The grain yield in HNES was more dependent on the effective accumulative temperature. Conclusions: Sowing in mid-May and increasing the N application (180 kg ha−1) are beneficial to the allocation of light temperature and the increase in yield. Therefore, this research provides a theoretical basis for improving rice yield and optimizing the utilization of light-temperature resources in the future. [ABSTRACT FROM AUTHOR]

Facing the era of information explosion and the advent of artificial intelligence, there is a growing demand for information technologies with huge storage capacity and efficient computer processing. However, traditional silicon-based storage and computing technology will reach their limits and cannot meet the post-Moore information storage requirements of ultrasmall size, ultrahigh density, flexibility, biocompatibility, and recyclability. As a response to these concerns, polymer-based resistive memory materials have emerged as promising candidates for next-generation information storage and neuromorphic computing applications, with the advantages of easy molecular design, volatile and non-volatile storage, flexibility, and facile fabrication. Herein, we first summarize the memory device structures, memory effects, and memory mechanisms of polymers. Then, the recent advances in polymer resistive switching materials, including single-component polymers, polymer mixtures, 2D covalent polymers, and biomacromolecules for resistive memory devices, are highlighted. Finally, the challenges and future prospects of polymer memory materials and devices are discussed. Advances in polymer-based memristors will open new avenues in the design and integration of high-performance switching devices and facilitate their application in future information technology. [ABSTRACT FROM AUTHOR]

A simple vibration sensor is proposed and demonstrated based on an optical fiber Fabry-Perot interferometer (FPI) with an in-fiber collimator. The device was fabricated by splicing a quarter-pitch graded index fiber (GIF) with a section of a hollow-core fiber (HCF) interposed between single mode fibers (SMFs). The static displacement sensitivity of the FPI with an in-fiber collimator was 5.17 × 10−4 μm−1, whereas the maximum static displacement sensitivity of the device without collimator was 1.73 × 10−4 μm−1. Moreover, the vibration sensitivity of the FPI with the collimator was 60.22 mV/g at 100 Hz, which was significantly higher than the sensitivity of the FPI without collimator (11.09 mV/g at 100 Hz). The proposed FPI with an in-fiber collimator also exhibited a vibration sensitivity nearly one order of magnitude higher than the device without the collimator at frequencies ranging from 40 to 200 Hz. This low-cost FPI sensor is highly-sensitive, robust and easy to fabricate. It could potentially be used for vibration monitoring in remote and harsh environments. [ABSTRACT FROM AUTHOR]

The combination of organic and inorganic materials has been considered an effective solution for achieving ambient thermoelectric energy harvesting and has been developing rapidly. Here, PEDOT:PSS/MWCNT (PPM) composite hydrogels were synthesized using the self-assembled gelation process of poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) and the interaction between PEDOT:PSS and multi-walled carbon nanotubes (MWCNTs) without the addition of any surfactant. After immersion in dimethyl sulfoxide and freeze-drying, the hydrogel is easily dispersed in water and used as a direct ink writing (DIW) 3D printing ink. At room temperature, the PPM-20 printed film with 20 wt% MWCNT solids achieved a maximum power factor of 7.37 μW m−1 K−2 and maintained stable thermoelectric properties during repeated bending cycles. On this basis, a thermoelectric generator (TEG) consisting of five legs was printed, which could be produced to generate an open circuit voltage of 6.4 mV and a maximum output power of 40.48 nW at a temperature gradient of 50 K, confirming its great potential for application in high-performance flexible organic/inorganic thermoelectric materials. [ABSTRACT FROM AUTHOR]

Previous studies have shown that coal-based solid waste can be utilized in combination with cement, silica fume, and other modified materials to create a cemented backfill material. However, traditional cemented backfill materials have poor mechanical properties, which may induce the emergence of mining pressure and trigger dynamic disaster under complex mining conditions. In this study, the nanocomposite fiber was used to modify the traditional cemented backfill materials and a new cemented backfill material was developed using coal-based solid waste, nanocomposite fiber and other materials. Specifically, coal gangue, fly ash, cement, and glass fibers were used as the basic materials, different mass fractions of nano-SiO2 were used to prepare cemented backfill materials, and the mechanical enhancement effect of the compressive strength, tensile strength, and shear strength of the modified materials was analyzed. The results show that when the nano-SiO2 dosage is 1%, the optimal compressive strength of the specimens at the curing age of 7 d can be obtained compared with cemented materials without nano-SiO2, and the compressive strength of the modified specimens raises by 84%; when the nano-SiO2 dosage is 1%, the optimal tensile strength and shear strengths of the modified specimens can be obtained at the curing age of 28 d, increasing by 82% and 142%. The results reveal that nanocomposite fibers can be used as additives to change the mechanical properties of cemented backfill materials made using coal-based solid waste. This study provides a reference for the disposal of coal-based solid waste and the enhancement of the mechanical properties of cemented backfill materials. [ABSTRACT FROM AUTHOR]

In the process of production, processing, transportation, and storage of edible oils, the oils inevitably come into contact with plastic products. As a result, plasticizers migrate into edible oils, are harmful to human health, and can exhibit reproductive toxicity. Therefore, the determination of plasticizers in edible oils is very important, and a series of sample preparation methods and determination techniques have been developed for the determination of plasticizers in edible oils. Phthalic acid ester (PAE) plasticizers are the most widely used among all plasticizers. This review aims to provide a comprehensive overview of the sample preparation methods and detection techniques reported for the determination of PAEs in edible oils since 2010, focusing on sample preparation methods of edible oils combined with various separation-based analytical techniques, such as gas chromatography (GC) and liquid chromatography (LC) with different detectors. Furthermore, the advantages, disadvantages, and limitations of these techniques as well as the prospective future developments are also discussed. [ABSTRACT FROM AUTHOR]

Coordination polymers (CPs) are organo-inorganic porous materials consisting of metal ions or clusters and organic linkers. These compounds have attracted attention for use in the fluorescence detection of pollutants. Here, two Zn-based mixed-ligand-bearing CPs, [Zn2(DIN)2(HBTC2−)2] (CP-1) and [Zn(DIN)(HBTC2−)]·ACN·H2O (CP-2) (DIN = 1,4-di(imidazole-1-yl)naphthalene, H3BTC = 1,3,5-benzenetricarboxylic acid, and ACN = acetonitrile), were synthesized under solvothermal conditions. CP-1 and CP-2 were characterized by single-crystal X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis, elemental analysis, and powder X-ray diffraction analysis. Solid-state fluorescence analysis revealed an emission peak at 350 nm upon excitation at 225 and 290 nm. Fluorescence sensing tests showed that CP-1 was highly efficient, sensitive, and selective for detecting Cr2O72− at 225 and 290 nm, whereas I− was only detected well at an excitation of 225 nm. CP-1 detected pesticides differently at excitation wavelengths of 225 and 290 nm; the highest quenching rates were for nitenpyram at 225 nm and imidacloprid at 290 nm. The quenching process may occur via the inner filter effect and fluorescence resonance energy transfer. [ABSTRACT FROM AUTHOR]

Acute respiratory distress syndrome (ARDS) is a common life-threatening clinical syndrome which accounts for 10% of intensive care unit admissions. Since the Berlin definition was developed, the clinical diagnosis and therapy have changed dramatically by adding a minimum positive end-expiratory pressure (PEEP) to the assessment of hypoxemia compared to the American-European Consensus Conference (AECC) definition in 1994. High-flow nasal cannulas (HFNC) have become widely used as an effective respiratory support for hypoxemia to the extent that their use was proposed in the expansion of the ARDS criteria. However, there would be problems if the diagnosis of a specific disease or clinical syndrome occurred, based on therapeutic strategies. [ABSTRACT FROM AUTHOR]

Polysaccharides are the main bioactive components in safflower. In this study, safflower polysaccharides (SPs) were extracted by ultrasonic assisted extraction, and four purified safflower polysaccharide fractions (named SSP1, SSP2, SSP3, and SSP4, respectively) were obtained. The physicochemical properties and in vitro physiological activities of the four fractions were investigated. The molecular weights (MW) of the SSPs were 38.03 kDa, 43.17 kDa, 54.49 kDa, and 76.92 kDa, respectively. Glucuronic acid, galactose acid, glucose, galactose, and arabinose were the main monosaccharides. The Fourier transform infrared spectroscopy (FT-IR) indicated that the polysaccharides had α- and β-glycosidic bonds. Nuclear magnetic resonance (NMR) analysis showed that SSP1 had 6 different types of glycosidic bonds, while SSP3 had 8 different types. SSP3 exhibited relatively higher ABTS+ scavenging activity, Fe+3-reduction activity, and antiproliferative activity. The results will offer a theoretical framework for the use of SPs in the industry of functional foods and medications. [ABSTRACT FROM AUTHOR]

Due to the large molecular weight and complex structure of Laminaria japonica polysaccharides (LJP), which limit their absorption and utilization by the body, methods to effectively degrade polysaccharides had received more and more attention. In the present research, hot water extraction coupled with three-phase partitioning (TPP) was developed to extract and isolate LJP. Ultrasonic L. japonica polysaccharides (ULJP) were obtained by ultrasonic degradation. In addition, their physicochemical characteristics and in vitro biological activities were investigated. Results indicated that ULJP had lower weight-average molecular weight (153 kDa) and looser surface morphology than the LJP. The primary structures of LJP and ULJP were basically unchanged, both contained α-hexo-pyranoses and were mainly connected by 1,4-glycosidic bonds. Compared with LJP, ULJP had stronger antioxidant activity, α-amylase inhibitory effect and anti-inflammatory effect on RAW264.7 macrophages. The scavenging rate of DPPH free radicals by ULJP is 35.85%. Therefore, ultrasonic degradation could effectively degrade LJP and significantly improve the biological activity of LJP, which provided a theoretical basis for the in-depth utilization and research and development of L. japonica in the fields of medicine and food. [ABSTRACT FROM AUTHOR]

A quantitative structure–activity relationship (QSAR) model for the structure and affinity of abrin aptamers was established. A higher affinity abrin aptamer based on the established QSAR model was screened by site-directed mutagenesis. The fluorescence quenching effect between magnetic microspheres and fluorescent molecules was studied for the first time. A new method for abrin detection based on the interaction between target molecules and fluorescently labeled aptamers on magnetic microspheres was developed, with the detection limit of 5 ng mL−1. This method can overcome the influence of complex environmental interferents in abrin detection and can meet the analysis requirements for simulated samples such as water, soil, and food. [ABSTRACT FROM AUTHOR]

Multiple in vitro and in vivo model investigations have suggested a broad spectrum of potential mechanisms by which plant/macrofungi-derived non-starch polysaccharides may play a role in the treatment of inflammatory bowel disease (IBD). This article reviews the in vivo and in vitro evidence of different plant-derived polysaccharides for IBD therapy. Their underlying mechanisms, particularly the molecular mechanisms associated with protective effects in the treatment and prevention of IDB, have been well summarized, including anti-inflammatory, epithelial barrier repair, and the regulation of intestinal flora. Emerging studies have observed the potent role of probiotics in IBD, particularly its ability to modulate gut microbiota, a well-known key factor for IBD. In summary, plant/macrofungi-derived polysaccharides have the potential to be a promising agent for the adjuvant treatment and prevention of IBD and will contribute to the design of well-designed clinical intervention trials that will ultimately improve the therapy of IBD. [ABSTRACT FROM AUTHOR]

A sensitive dual-readout immunosensor for fluorescence and electrochemiluminescence (ECL) detection of ricin was established, which was combined with a streptavidin–biotin signal amplification system. CdSe/ZnS quantum dots with fine fluorescence and ECL properties were used as the dual-signal function probes of the sandwich immunocomplex. Under the optimum experimental conditions, the dual signal intensity increased significantly with the rise in ricin concentration. The fluorescence intensity of the senor exhibited a good liner relationship toward the ricin concentrations with 0.1~100 ng/mL and the limit of detection (LOD) was 81.7 pg/mL; taking ECL as the detection signal, the sensor showed a linear relationship with the ricin concentrations ranging from 0.01 ng/mL to 100 ng/mL and the LOD was 5.5 pg/mL. The constructed sensor with high sensitivity had been successfully applied to the detection of ricin in complex matrices with satisfactory recoveries. The proposed immunosensor model can be extended to the analysis and detection of others target proteins. [ABSTRACT FROM AUTHOR]

High-accuracy temperature measurement plays a vital role in biomedical, oceanographic, and photovoltaic industries. Here, a highly sensitive temperature sensor is proposed and demonstrated based on cascaded polymer-infiltrated Mach–Zehnder interferometers (MZIs), operating near the dispersion turning point. The MZI was constructed by splicing a half-pitch graded index fiber (GIF) and two sections of single-mode fiber and creating an inner air cavity based on femtosecond laser micromachining. The UV-curable polymer-infiltrated air cavity functioned as one of the interference arms of MZI, and the residual GIF core functioned as the other. Two MZIs with different cavity lengths and infiltrated with the UV-curable polymers, having the refractive indexes on the different sides of the turning point, were created. Moreover, the effects of the length and the bending way of transmission SMF between the first and the second MZI were studied. As a result, the cascaded MZI temperature sensor exhibits a greatly enhanced temperature sensitivity of −24.86 nm/°C based on wavelength differential detection. The aforementioned result makes it promising for high-accuracy temperature measurements in biomedical, oceanographic, and photovoltaic applications. [ABSTRACT FROM AUTHOR]

We propose and demonstrate a novel high-temperature-resistant vector accelerometer, consisting of a ring cavity laser and sensing probe (i.e., fiber Bragg gratings (FBGs)) inscribed in a seven-core fiber (SCF) by using the femtosecond laser direct writing technique. A ring cavity laser serves as a light source. Three FBGs in the outer cores of SCF, which are not aligned in a straight line, are employed to test the vibration. These three FBGs have 120° angular separation in the SCF, and hence, vibration orientation and acceleration can be measured simultaneously. Moreover, the FBG in the central core was used as a reflector in the ring cavity laser, benefiting to resist external interference factors, such as temperature and strain fluctuation. Such a proposed accelerometer exhibits a working frequency bandwidth ranging from 4 to 68 Hz, a maximum sensitivity of 54.2 mV/g, and the best azimuthal angle accuracy of 0.21° over a range of 0–360°. Furthermore, we investigated the effect of strain and temperature on the performance of this sensor. The signal-to-noise ratio (SNR) only exhibits a fluctuation of ~1 dB in the range (0, 2289 με) and (50 °C, 1050 °C). Hence, such a vector accelerometer can operate in harsh environments, such as in aerospace and a nuclear reactor. [ABSTRACT FROM AUTHOR]

While the detection of offshore ships in synthetic aperture radar (SAR) images has been widely studied, inshore ship detection remains a challenging task. Due to the influence of speckle noise and the high similarity between onshore buildings and inshore ships, the traditional methods are unable to achieve effective detection for inshore ships. To improve the detection performance of inshore ships, we propose a novel saliency enhancement algorithm based on the difference of anisotropic pyramid (DoAP). Considering the limitations of IoU in small-target detection, we design a detection framework based on the proposed Bhattacharyya-like distance (BLD). First, the anisotropic pyramid of the SAR image is constructed by a bilateral filter (BF). Then, the differences between the finest two scales and the coarsest two scales are used to generate the saliency map, which can be used to enhance ship pixels and suppress background clutter. Finally, the BLD is used to replace IoU in label assignment and non-maximum suppression to overcome the limitations of IoU for small-target detection. We embed the DoAP into the BLD-based detection framework to detect inshore ships in large-scale SAR images. The experimental results on the LS-SSDD-v1.0 dataset indicate that the proposed method outperforms the basic state-of-the-art detection methods. [ABSTRACT FROM AUTHOR]

Polylactic acid (PLA) is expected to be widely used in green power equipment manufacturing due to its good mechanical properties and biodegradability. In this paper, the effects of MgO with different particle sizes and mass fractions on the thermal and electrical properties of PLA composites were studied. The experiment found that with the increase in MgO particle sizes and mass fractions, the thermal conductivity of MgO/PLA composites showed a rising trend, which was up to 165.4% higher than that of pure PLA. However, the heat resistance first increases and then decreases. For the electrical properties of MgO/PLA composites, the breakdown strength and volume resistivity decrease with an increase in MgO particle size and mass fraction. In order to further study the influence mechanism of the introduction of MgO with different particle sizes and mass fractions on the thermal and electrical properties of MgO/PLA composites, molecular dynamics simulation was used to simulate the glass transition temperature (Tg) of PLA composites doped with MgO of different particle sizes, and it was found that MgO doping weakened the movement of the PLA molecular chain segment. Using density functional theory (DFT) calculations, it was found that in the MgO and PLA system, electrons have a tendency to migrate from the PLA matrix to MgO, which causes the formation of electron traps at the inorganic–organic interface and affects its electrical properties. The purpose of this study is to provide a theoretical reference for PLA composites in the manufacture of power equipment. [ABSTRACT FROM AUTHOR]

To satisfy the need to develop highly sensitive methods for detecting the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and further enhance detection efficiency and capability, a new method was created for detecting SARS-CoV-2 of the open reading frames 1ab (ORF1ab) target gene by a electrochemiluminescence (ECL) biosensor based on dual-probe hybridization through the use of a detection model of "magnetic capture probes—targeted nucleic acids—Ru(bpy)32+ labeled signal probes". The detection model used magnetic particles coupled with a biotin-labeled complementary nucleic acid sequence of the SARS-CoV-2 ORF1ab target gene as the magnetic capture probes and Ru(bpy)32+ labeled amino modified another complementary nucleic acid sequence as the signal probes, which combined the advantages of the highly specific dual-probe hybridization and highly sensitive ECL biosensor technology. In the range of 0.1 fM~10 µM, the method made possible rapid and sensitive detection of the ORF1ab gene of the SARS-CoV-2 within 30 min, and the limit of detection (LOD) was 0.1 fM. The method can also meet the analytical requirements for simulated samples such as saliva and urine with the definite advantages of a simple operation without nucleic acid amplification, high sensitivity, reasonable reproducibility, and anti-interference solid abilities, expounding a new way for efficient and sensitive detection of SARS-CoV-2. [ABSTRACT FROM AUTHOR]

In this study, the polymer PTSPM-PMETAC with anion adsorption properties was prepared by a one-step method, then the amino-modified nano-SiO2 was grafted onto the polymer to improve the roughness of the surface and enhance the stability of superhydrophobic properties, and a high-stability superhydrophobic paper with ion-induced wettability transition properties was successfully prepared. The study found that the paper can realize the reversible control of surface wettability through the exchange between the anions PF6− and Cl− adsorbed on the surface of PMETAC, and further investigation of the effect of different solvents on the ion exchange properties found that water was the poor solvent for ion exchange, while the mixtures of methanol, acetone, and methanol & water were the good solvent. On the whole, the preparation of superhydrophobic paper by this method not only simple in preparation process, low in cost and strong in universality, but also the prepared superhydrophobic paper has high transparency and good stability, which has great application potential in industrial production. [ABSTRACT FROM AUTHOR]

For the convenience of fast measurement in the outdoor environment, a portable electrochemiluminescence biosensor with the screen-printed electrode as the reaction center was developed, which possesses the characteristics of high sensitivity, small scale, simplified operation and so on, and has been used for in situ detection of abrin. First, combining with magnetic separation technique, the “biotin-avidin” method was used to immobilize the polyclonal antibody (pcAb) on the magnetic microspheres surface as the capture probe. Secondly, the Ru(bpy)32+-labeled monoclonal antibody (mcAb) was used as the specific electrochemiluminescence signal probe. Then, the “mcAb-toxin-pcAb” sandwich model was built to actualize the quantitative detection of abrin on the surface of the screen-printed electrode. The linear detection range was 0.5–1000 ng/mL; the regression equation was Y = 89.251lgX + 104.978 (R = 0.9989, n = 7, p < 0.0001); and the limit of detection (LOD) was 0.1 ng/mL. The sensing system showed high sensitivity, excellent specificity and good anti-interference ability, and could be used for the analysis of trace abrin in various environmental samples with good recovery and reproducibility. Compared with the traditional electrochemiluminescence sensing device, its miniaturization and portability gives it potential to satisfy the requirement of in situ detection. [ABSTRACT FROM AUTHOR]

A nondestructive measurement method based on an Optical frequency domain reflectometry (OFDR) was demonstrated to achieve Young's modulus of an optical fiber. Such a method can be used to measure, not only the averaged Young's modulus within the measured fiber length, but also Young's modulus distribution along the optical fiber axis. Moreover, the standard deviation of the measured Young's modulus is calculated to analyze the measurement error. Young's modulus distribution of the coated and uncoated single mode fiber (SMF) samples was successfully measured along the optical fiber axis. The average Young's modulus of the coated and uncoated SMF samples was 13.75 ± 0.14, and 71.63 ± 0.43 Gpa, respectively, within the measured fiber length of 500 mm. The measured Young's modulus distribution along the optical fiber axis could be used to analyze the damage degree of the fiber, which is very useful to nondestructively estimate the service life of optical fiber sensors immersed into smart engineer structures. [ABSTRACT FROM AUTHOR]

Nitrogen fertilizer and planting density are key factors affecting rice yield and nitrogen utilization efficiency. There is still a need to optimize nitrogen fertilizer and planting density management for high yield. We studied the effects of different quantities of nitrogen application (N0 0 kg ha−1, N1 120 kg ha−1, N2 180 kg ha−1) and planting density (low-density: 18.8 hills m−2; high-density: 37.5 hills m−2) on rice yield, photosynthetic characteristics, antioxidant system, and nitrogen use efficiency. ANOVA results indicated that most tested traits were affected by environment, planting density, N application, and their interactions. Comparing the results of low-density planting, high-density planting increased the panicle number by 21.12% but decreased the grain number per panicle and yield by 3.97% and 22.48%, respectively. Similarly, the superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and ascorbate peroxidase (APX) activities and PFPn (partial factor productivity of nitrogen) decreased by 8.20%, 6.99%, 16.41%, 14.28%, and 5.73%, respectively, while HIn (N harvest index) increased by 1.32%. Compared to no N application, N application treatments increased the panicle number, grain number per panicle, and yield by 9.92%, 17.64%, and 37.83% in the N1 treatment; and increased by 17.15%, 29.09%, and 128.94% in the N2 treatment, respectively. N application significantly increased net photosynthetic rates and enzyme activities of antioxidant antioxidases. Compared with N1, N2 decreased REn (apparent recovery efficiency of N), AEn (agronomic N use efficiency), and PFPn by 8.98%, 11.80%, and 25.14%, respectively, while, compared with N0, N1 increased HIn by 8.50%. It was observed that nitrogen fertilizer and planting density had an interaction effect on the net photosynthetic rate, antioxidant enzyme activities, and PFPn and HIn. Given a comprehensive consideration, it is best to apply nitrogen at a rate of 120 kg ha−1 at the planting density of 37.5 hills m−2 for high grain yield and high N use efficiency in our experimental site. [ABSTRACT FROM AUTHOR]

Chronic wound repair is a common complication in patients with diabetes mellitus, which causes a heavy burden on social medical resources and the economy. Hypaphorine (HYP) has good anti-inflammatory effect, and chitosan (CS) is used in the treatment of wounds because of its good antibacterial effect. The purpose of this research was to investigate the role and mechanism of HYP-nano-microspheres in the treatment of wounds for diabetic rats. The morphology of HYP-NPS was observed by transmission electron microscopy (TEM). RAW 264.7 macrophages were used to assess the bio-compatibility of HYP-NPS. A full-thickness dermal wound in a diabetic rat model was performed to evaluate the wound healing function of HYP-NPS. The results revealed that HYP-NPS nanoparticles were spherical with an average diameter of approximately 50 nm. The cell experiments hinted that HYP-NPS had the potential as a trauma material. The wound test in diabetic rats indicated that HYP-NPS fostered the healing of chronic wounds. The mechanism was through down-regulating the expression of pro-inflammatory cytokines IL-1β and TNF-α in the skin of the wound, and accelerating the transition of chronic wound from inflammation to tissue regeneration. These results indicate that HYP-NPS has a good application prospect in the treatment of chronic wounds. [ABSTRACT FROM AUTHOR]

Fly ash cement is used to solidify marine clay to prepare marine-clay-based cemented paste backfill (MCCPB) to fill the underground goaf of mines, which not only utilizes solid waste such as fly ash and marine clay, but also controls surface subsidence and protects the environment. To simulate the complex underground mine water environment of the filling body, a dry-wet cycle aquatic environment test under different material ratios and curing ages was designed. The water absorption and unconfined compression strength (UCS) of MCCPB with curing ages of 7 and 28 days under the action of 0, 1, 3, and 7 dry-wet cycles were investigated. The results indicate as the number of dry-wet cycles increases, the surface of MCCPB becomes significantly rougher, and the water content and the solid mass decrease accordingly. Different ratios and curing ages of MCCPB in dry-wet cycles of the UCS tend first to increase, then decrease. Meanwhile, the stress-strain curve of the specimen shows that the trend in the elastic modulus is consistent with that of UCS (first increasing, then decreasing), and that, the minimum UCS value of the specimen still meets the early strength requirements of cemented paste backfill in coal mine geothermal utilization. On the one hand, it proves the feasibility of fly ash cement-solidified marine clay for use as cemented paste backfill in coal mines; on the other hand, it also expands the available range of cemented paste backfill materials in coal mines. [ABSTRACT FROM AUTHOR]

We demonstrate a silica diaphragm-based fiber tip Fabry–Perot interferometer (FPI) for high-pressure (40 MPa) sensing. By using a fiber tip polishing technique, the thickness of the silica diaphragm could be precisely controlled and the pressure sensitivity of the fabricated FPI sensor was enhanced significantly by reducing the diaphragm thickness; however, the relationship between the pressure sensitivity and diaphragm thickness is not linear. A high sensitivity of −1.436 nm/MPa and a linearity of 0.99124 in hydraulic pressure range of 0 to 40 MPa were demonstrated for a sensor with a diaphragm thickness of 4.63 μm. The achieved sensitivity was about one order of magnitude higher than the previous results reported on similar fiber tip FPI sensors in the same pressure measurement range. Sensors with a thinner silica diaphragm (i.e., 4.01 and 2.09 μm) rendered further increased hydraulic pressure sensitivity, but yield a significant nonlinear response. Two geometric models and a finite element method (FEM) were carried out to explain the nonlinear response. The simulation results indicated the formation of cambered internal silica surface during the arc discharge process in the fiber tip FPI sensor fabrication. [ABSTRACT FROM AUTHOR]

Sea bass (Lateolabrax maculatus) is a kind of food material commonly consumed in daily life. In traditional Chinese medicinal books, it has been indicated that sea bass can be applied for managing many inflammation-associated conditions. However, the studies on the pharmacological mechanisms of inflammation of sea bass remain scarce. Hence, this study aims to investigate the molecular mechanisms of the anti-inflammatory activity of sea bass. Anti-inflammatory activities of sea bass were assessed using dextran sulfate sodium (DSS)-induced colitis in a mice model and lipopolysaccharide (LPS)-activated macrophages model. Low body weight and short colon length were observed in DSS-fed mice that were significantly recovered upon sea bass treatments. Moreover, the colon histopathology score showed that sea bass-treated mice had decreased crypt damage, focal inflammation infiltration and the extent of inflammation, suggesting that treatment with sea bass could attenuate intestinal inflammation. In addition, the in-vitro study conjointly indicated that sea bass could suppress the inflammatory mediators in LPS-activated macrophage by inhibiting the TLR4-linked pathway. The present findings demonstrated that sea bass has an inhibitory effect on TLR4 signaling; thus, it could be a promising candidate for treating inflammation-associated conditions. A further justification for the clinical application of sea bass in treating inflammation-associated conditions is necessary. [ABSTRACT FROM AUTHOR]