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1. Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample

Author

Jarle Johannessen, Terje Nærland, Sigrun Hope, Tonje Torske, Anne Lise Høyland, Jana Strohmaier, Arvid Heiberg, Marcella Rietschel, Srdjan Djurovic, and Ole A. Andreassen

Subjects
ASD, autism, Asperger syndrome, clinical genetic testing, parents, attitudes, ethics, genetic counselling, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract

Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to assess parents’ attitudes toward CGT for ASD. Parent members of the Norwegian Autism Society were given a previously untested questionnaire and 1455 answered. Linear regression analyses were conducted to evaluate contribution of parent and child characteristics to attitude statements. Provided it could contribute to a casual explanation of their child’s ASD, 76% would undergo CGT. If it would improve the possibilities for early interventions, 74% were positive to CGT. Between 49–67% agreed that CGT could have a negative impact on health insurance, increase their concern for the child’s future and cause family conflicts. Parents against CGT (9%) were less optimistic regarding positive effects, but not more concerned with negative impacts. The severity of the children’s ASD diagnosis had a weak positive association with parent’s positive attitudes to CGT (p-values range from

Published
2017
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2. Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample

Author

Sigrun Hope, Arvid Heiberg, Ole A. Andreassen, Jarle Johannessen, Jana Strohmaier, Tonje Torske, Marcella Rietschel, Anne Lise Høyland, Srdjan Djurovic, and Terje Nærland

Subjects
Male, 0301 basic medicine, Autism Spectrum Disorder, Psychological intervention, 030105 genetics & heredity, lcsh:Chemistry, Surveys and Questionnaires, lcsh:QH301-705.5, Spectroscopy, attitudes, medicine.diagnostic_test, Norway, parents, General Medicine, Computer Science Applications, Autism spectrum disorder, language, Female, Psychology, Clinical psychology, medicine.medical_specialty, Genetic counseling, ASD, autism, Asperger syndrome, clinical genetic testing, ethics, genetic counselling, Norwegian, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, mental disorders, medicine, Humans, Genetic Testing, Autistic Disorder, Physical and Theoretical Chemistry, Psychiatry, Molecular Biology, Genetic testing, Ethics, Organic Chemistry, medicine.disease, language.human_language, Attitude, lcsh:Biology (General), lcsh:QD1-999, Linear Models, Autism
Abstract

Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to assess parents’ attitudes toward CGT for ASD. Parent members of the Norwegian Autism Society were given a previously untested questionnaire and 1455 answered. Linear regression analyses were conducted to evaluate contribution of parent and child characteristics to attitude statements. Provided it could contribute to a casual explanation of their child’s ASD, 76% would undergo CGT. If it would improve the possibilities for early interventions, 74% were positive to CGT. Between 49–67% agreed that CGT could have a negative impact on health insurance, increase their concern for the child’s future and cause family conflicts. Parents against CGT (9%) were less optimistic regarding positive effects, but not more concerned with negative impacts. The severity of the children’s ASD diagnosis had a weak positive association with parent’s positive attitudes to CGT (p-values range from

Published
2017

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