1. Colistin-induced myasthenic syndrome in a patient with end-stage renal disease.
- Author
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Sengupta P and Biswas S
- Subjects
- Drug Resistance, Multiple, Bacterial, Female, Humans, Kidney Failure, Chronic diagnosis, Kidney Failure, Chronic therapy, Klebsiella Infections complications, Klebsiella Infections diagnosis, Klebsiella Infections microbiology, Middle Aged, Muscle Weakness diagnosis, Muscle Weakness physiopathology, Muscle Weakness therapy, Neuromuscular Junction physiopathology, Neuromuscular Junction Diseases diagnosis, Neuromuscular Junction Diseases physiopathology, Neuromuscular Junction Diseases therapy, Recovery of Function, Syndrome, Treatment Outcome, Urinary Tract Infections complications, Urinary Tract Infections diagnosis, Urinary Tract Infections microbiology, Anti-Bacterial Agents adverse effects, Colistin adverse effects, Kidney Failure, Chronic complications, Klebsiella Infections drug therapy, Muscle Weakness chemically induced, Neuromuscular Junction drug effects, Neuromuscular Junction Diseases chemically induced, Urinary Tract Infections drug therapy
- Abstract
With resurgence of multidrug resistance (MDR) bacteria and no new novel broad-spectrum antibiotic in research pipeline, usage of older generation antibiotics, once discarded due to their toxicity profile are becoming popular again. Often these drugs are the only option left in managing MDR bacteria-related sepsis. Colistin is one of such antibiotic which is often used in recent times after decades of its avoidance due to its diverse toxicity profile. In this case report, we present a rare myasthenic syndrome like neuromuscular complication developed in a patient after receiving colistin for treatment of MDR Klebsiella-related urosepsis., Competing Interests: None declared
- Published
- 2018
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