Search

A report from the Veterans Health Service Medical Center in Seoul, South Korea explores the association between multiple job-holding (MJH) and physical and psychological symptoms among Korean workers. The study found that MJH was associated with increased symptoms of headache or eyestrain and anxiety. Gender-stratified analyses showed that women MJHers experienced a higher prevalence of musculoskeletal pain, headache or eyestrain, fatigue, insomnia, and anxiety compared to men. The researchers suggest that further research is needed to understand the social context of MJH and to develop interventions to support the well-being of MJHers. [Extracted from the article]

The article discusses the use of the Analgesia Nociception Index (ANI) monitor to assess the effectiveness of an epidural blood patch (EBP) in treating spontaneous intracranial hypotension (SIH). Topics include the role of ANI in evaluating treatment success, the correlation between ANI values and headache relief, and the potential for ANI monitoring to guide therapeutic interventions for SIH.

The article from the Department of Neurosurgery reports a novel case of spontaneous intracranial hypotension (SIH) caused by a cerebrospinal fluid (CSF) venous fistula, which led to venous sinus thrombosis and coma. The patient presented with atypical symptoms, including tinnitus and cranial nerve issues, and had low intracranial pressure confirmed by invasive monitoring and imaging.

A recent study conducted by researchers at Hamad Medical Corporation in Doha, Qatar, has highlighted the chronic consequences of accidental dural puncture (ADP) and postdural puncture headache (PDPH) in obstetric anesthesia. The study found that ADP can lead to a high rate of PDPH, prolonged hospitalization, and increased readmissions. Furthermore, PDPH can result in chronic complications such as postpartum depression, posttraumatic stress disorder, chronic headache, backache, and reduced breastfeeding rates. The researchers emphasize the importance of appropriate diagnosis and treatment for women experiencing ADP and PDPH, as these conditions can have serious and potentially life-threatening consequences. [Extracted from the article]

A study conducted by Tarbiat Modares University in Tehran, Iran, explored the link between post-spinal anesthesia headaches and various factors in female candidates for cesarean sections. The study found no significant association between headaches and factors such as age, BMI, blood pressure, fasting blood sugar, duration of immobilization, and history of prior spinal anesthesia and post-dural puncture headache. The researchers concluded that anesthesia providers should consider all possible factors that could cause headaches in women who have undergone spinal anesthesia during cesarean sections. [Extracted from the article]

A recent report from the Kerala Institute of Medical Sciences in India discusses a case of a 14-year-old girl with congenital hydrocephalus and early-onset scoliosis who experienced a sudden severe headache after corrective surgery for scoliosis. The girl was found to have cerebellar hemorrhage and obstructive hydrocephalus. Despite initial treatment, the headache persisted until a dural tear at the D10 level was discovered and repaired, resulting in complete relief of the headache. This case highlights the rare occurrence of remote cerebellar hemorrhage following spinal surgeries with associated dural tear. [Extracted from the article]

A recent study conducted in Benin found that headache disorders are highly prevalent among children and adolescents in the country. The study used a schools-based approach and administered a structured questionnaire to a representative sample of pupils. The results showed that 97.3% of the sample reported experiencing headaches at some point. The most common types of headaches were migraine (53.4%), tension-type headache (21.3%), and undifferentiated headache (8.2%). The study also highlighted the emerging problem of probable medication-overuse headache among young people. [Extracted from the article]

A recent study conducted by researchers at Huazhong University of Science and Technology in Wuhan, China, evaluated the efficacy and safety of levetiracetam (LEV) for pediatric migraine prophylaxis. The study reviewed eight studies involving 190 participants and found that LEV significantly reduced mean headache frequency and improved headache-free rates in children with migraines. Additionally, more than 83% of participants experienced a >50% reduction in monthly headache frequency. The study concluded that LEV showed good efficacy in preventing pediatric migraines, but further research is needed to confirm its safety. [Extracted from the article]

A recent study conducted at Buckinghamshire Healthcare NHS Trust focused on a case of meningoencephalitis-like symptoms that turned out to be cerebral venous sinus thrombosis (CVST). The patient initially presented with fevers, headaches, and poor sleep, and was treated for meningoencephalitis. However, further examination revealed bilateral haemorrhages and confirmed CVST. The patient experienced long-term complications, including residual left-sided weakness and persistent headaches, requiring ongoing treatment and follow-up. The study emphasizes the importance of early multidisciplinary approaches in cases of headaches and seizures, as well as the need for long-term follow-up due to unpredictable complications. [Extracted from the article]

A researcher from G. D'Annunzio University in Italy has conducted a study on the co-occurrence of headache and visceral pain. The study found that these two conditions often exist together in patients and may share common underlying mechanisms. The researcher reviewed the associations between headache and pain from the cardiovascular, gastrointestinal, and urogenital areas, as well as primary headache conditions such as migraine and tension-type headache. The findings suggest that these associations involve complex interactions and have implications for diagnosis and treatment. Further information on the study can be found in the journal Diagnostics. [Extracted from the article]

A recent study from the University of California Los Angeles (UCLA) explores the role of caffeine in headache disorders. The research highlights the complex effects of caffeine on sleep, brain blood flow, and intracranial pressure, which may vary depending on the timing of caffeine intake. The study suggests that while caffeine can provide acute therapeutic benefits for some primary headache disorders, high levels of caffeine intake may contribute to the progression of these disorders. The researchers recommend limiting dietary caffeine intake to moderate amounts with consistent timing before noon and using caffeine-containing combination analgesics infrequently for milder headaches. However, there is currently insufficient evidence to support universal guidelines for the use of caffeine in headache disorders. [Extracted from the article]

A report from Jining Medical University in Shandong, China discusses the current understanding and management of cluster headaches. Cluster headaches are a type of severe headache that can significantly impact a patient's quality of life. The report highlights the challenges in diagnosing and treating cluster headaches, as well as the high levels of depression and suicidal tendencies often experienced by patients. The research also explores recent advances in understanding the underlying neurobiological mechanisms of cluster headaches, which may lead to more targeted and effective treatments in the future. [Extracted from the article]

A recent report from Strasbourg University Hospital in France discusses the coexistence of sleep-related painful erection (SRPE) and hypnic headache (HH). SRPE is characterized by painful erections during rapid eye movement (REM) sleep, while HH is a primary headache that occurs exclusively at night, often during REM sleep. The report describes the case of a 33-year-old man who experienced both conditions and explores the possible underlying pathophysiology. The researchers suggest that somnologists should be aware of the potential overlap between SRPE and HH, and patient reassurance is an important aspect of care. [Extracted from the article]

A recent study conducted in Cameroon found that headache disorders are highly prevalent and have a significant burden on individuals and society. The study used a population-based door-to-door survey to assess the needs for headache care in the country. The findings showed that a large percentage of adult Cameroonians require headache care, and the lack of access to care has economic costs. The study highlights the importance of providing adequate headache care in Cameroon to improve the quality of life and productivity of individuals affected by these disorders. [Extracted from the article]

Researchers at the University of Illinois have released new data on intracranial hypotension, a condition characterized by a lower-than-normal volume of cerebrospinal fluid (CSF) caused by leakage through the dural membrane. Spontaneous intracranial hypotension is an uncommon cause of headache, and individuals with connective tissue disorders such as Marfan syndrome are at increased risk. The primary manifestation of this condition is an orthostatic headache, often accompanied by nausea and vomiting. The researchers successfully diagnosed and treated a case of spontaneous intracranial hypotension associated with Marfan syndrome using an epidural blood patch. [Extracted from the article]

A recent study conducted at the University of Colorado aimed to identify distinct clinical and imaging subtypes of spontaneous intracranial hypotension (SIH) due to spinal cerebrospinal fluid (CSF) venous fistula (CVF). The study included 48 patients with SIH due to CVF and analyzed their clinical symptoms, pre-treatment brain MRI, and symptom duration. The findings revealed the existence of distinct SIH subtypes based on clinical and imaging presentations, challenging the reliance on classic orthostatic headache alone for diagnosis. Further research is needed to refine diagnostic criteria and enhance understanding of SIH's pathophysiology. [Extracted from the article]

The article focuses on a patent application for the acute and rapid treatment of headaches, such as migraines, using anti-CGRP antibodies. Topics include the role of Calcitonin Gene Related Peptide (CGRP) in migraine development, the use of CGRP-targeting antibodies for treatment, and the advancement of these therapies compared to existing treatments.

A patent has been issued to Aruene Corporation for a prophylactic treatment for migraine headaches. The invention relates to the diagnosis and treatment of neurological disorders, including migraines. The treatment apparatus includes circuitry to generate a magnetic field and a patient interface for the patient to enter subjective patient data. The treatment device can accurately record patient data and treatment parameters, allowing for more accurate diagnosis and treatment. The patent provides a method for prophylactic treatment of migraines using a handheld treatment device that generates electromagnetic pulses directed towards the patient's head. The treatment plan can be adjusted based on the patient's usage and selected icons in an electronic diary. [Extracted from the article]

A new report discusses research findings on cluster headache, a debilitating neurological disorder characterized by severe, unilateral pain and autonomic symptoms. The report focuses on the acute and preventive treatment strategies for cluster headache in Taiwan. The treatment approach in Taiwan involves a stepwise strategy, with high-flow oxygen and triptan nasal sprays being the mainstays of acute treatment. Verapamil is the first-line option for preventive treatment, with other alternatives available. However, there are still unmet needs in the management of cluster headache in Taiwan, and increased awareness and education among healthcare professionals are needed to improve diagnosis and management. [Extracted from the article]

A recent report from Hamad Medical Corporation in Doha, Qatar, discusses the case of a 38-year-old male with acromegaly, a chronic hormonal disorder characterized by excessive growth hormone secretion. The patient had been experiencing severe and frequent headaches despite previous treatments. However, after switching to pasireotide, the patient reported a rapid and complete resolution of headaches within a month, along with normalization of IGF-1 levels. This case highlights the challenges in managing acromegaly and suggests the potential usefulness of pasireotide for treatment-resistant headaches in acromegaly patients. [Extracted from the article]

A case report from Aga Khan University in Pakistan discusses a 29-year-old pregnant patient who experienced a headache after an unintended dural puncture during spinal anesthesia for a cesarean section. The headache was initially treated as a post-dural puncture headache until the patient developed seizures and was diagnosed with posterior reversible encephalopathy syndrome (PRES) through brain imaging. The patient's symptoms improved with medication, and she was discharged without any further issues. The researchers emphasize the importance of considering PRES in obstetric cases with unintended dural punctures and highlight the need for further research, particularly in the Asian population. [Extracted from the article]

A report from researchers at Children's Hospital Philadelphia discusses the treatment of post-traumatic headache (PTH) in youth. The report highlights the lack of established guidelines for treating PTH and emphasizes the need for more research in this area. Factors such as female sex, a high number of acute symptoms, and adolescent age were found to be associated with prolonged recovery from concussion and persistent PTH. The report suggests a collaborative care approach that combines various management strategies for the most effective treatment of PTH in children. [Extracted from the article]

A new study from King's College in London has developed practical recommendations for the acute pharmacological treatment of migraines. The International Headache Society (IHS) created a list of clinical questions based on practical issues in migraine management, and a group of international headache experts developed the recommendations. The recommendations are categorized into optimal and essential, providing treatment options for all settings, including those with limited access to migraine medications. The adoption of these international recommendations is expected to improve the quality of acute migraine treatment worldwide. [Extracted from the article]

A recent report from the Institute of Child Health in West Bengal, India discusses the case of a child with recurrent headache, fever, and diffuse meningeal enhancement on MRI. The researchers found that the child's symptoms were initially diagnosed as migraine, but further investigations revealed a diagnosis of juvenile neurolupus. The study emphasizes the importance of considering all clinical, biochemical, and imaging analyses to accurately diagnose conditions that may present with similar symptoms. This research provides valuable insights into the diagnosis and management of nervous system diseases and conditions in pediatric patients. [Extracted from the article]

A recent study conducted by researchers from the University of Mississippi examined the impact of migraine aura on headache-related disability. The study involved 554 adults with migraine who recorded their symptoms and psychological variables daily for 90 days using a digital app. The findings revealed that the presence of aura was associated with higher disability ratings during migraine episodes, but this effect was attributed to non-pain symptoms of migraine. The study highlights the importance of considering aura and associated symptoms when assessing migraine-related disability. [Extracted from the article]

The article provides information on a patent for devices and methods for determining the effectiveness of electric stimulation filed by the inventors Joseph P. Errico and Bruce J. Simon on May 12, 2021 and published online on August 6, 2024, assigned to Electrocore Inc. Topics include quote from the background information supplied by the inventors, inventors' summary information for the patent, and claims supplied by the inventors.

The article focuses on the use of scalp nerve block (SNB) to reduce headaches associated with sonication during transcranial magnetic resonance-guided focused ultrasound (MRgFUS) procedures. Topics include the prevalence of headaches in MRgFUS, the implementation and impact of the SNB protocol on headache intensity, and the effectiveness of SNB across different energy doses of sonication.

The article reports on a new clinical trial, NCT06551987, comparing Cognitive Behavioral Therapy for Insomnia (CBT-I) with Brief Behavioral Therapy for Insomnia (BBT-I) in military personnel with insomnia and persistent postconcussive symptoms from mild traumatic brain injury (mTBI). Topics include treatment comparison, postconcussive symptoms, and insomnia severity.

The article reports on a clinical trial comparing the efficacy and safety of dabigatran and apixaban in treating first-time cerebral venous thrombosis. Topics include the rate of recurrent venous thromboembolism, the Modified Rankin Scale for disability assessment, and the incidence of hemorrhagic complications.

The article reports on a new clinical trial of comparing the efficacy and safety of dabigatran versus rivaroxaban in treating first-time cerebral venous thrombosis. Topics discussed include the rates of recurrent venous thromboembolism, drug-related hemorrhagic complications, and venous recanalization outcomes.

The article introduces a prospective observational study, NCT06543914, which aims to evaluate the effectiveness of atogepant in treating migraines within routine clinical settings. It higlights the study will involve around 1000 participants worldwide, who will use atogepant as prescribed by their doctors and be monitored over two years. Topics include the study's global participant recruitment, the real-world application of atogepant, and the study's schedule for assessing treatment efficacy.

This article provides a review of the literature on primary headache associated with sexual activity (PHASA). The research highlights the challenges in understanding the pathophysiology of PHASA and emphasizes the importance of conducting a thorough workup to rule out potentially life-threatening causes of headaches during sexual activity. The article also discusses the comorbidity of PHASA with other types of headaches and suggests various treatment options, including preemptive and prophylactic approaches. While there are some case reports suggesting the efficacy of CGRP-targeted therapies, further research is needed to establish their specific effectiveness. [Extracted from the article]

A recent report from University College London (UCL) discusses the use of artificial intelligence (AI) and machine learning (ML) in the field of headache research. The report highlights several key research topics, including the use of natural language processing to extract and systematize headache data, the classification of headache disorders using ML, and the prediction of headache disease trajectories and treatment responses. However, the report also notes that many studies in this area lack proper reporting and validation in a clinical setting. Overall, the potential uses of AI and ML in headache research are promising but require further development and evaluation. [Extracted from the article]

A study conducted at University Hospital Donostia in Donostia San Sebastian, Spain, explores the use of behavioral therapy (BT) as a treatment for migraines. The study found that BT may reduce the impact of migraines by decreasing the sympathetic nervous system's response to stress and increasing pain tolerance. It also suggests that BT can improve headache-related symptoms, duration, and self-efficacy. The advantages of BT include its lack of adverse effects and its effectiveness in children. While BT may not cure migraines, it can help reduce pain severity, disability, and overall impact. The study encourages the incorporation of nonpharmacological interventions in migraine treatment and further investigation into the effectiveness of these techniques. [Extracted from the article]

A recent study conducted by the Beijing Institute of Technology in China explored the decline in tactile discrimination in young patients with migraine without aura (MOA) or tension-type headache (TTH). The study aimed to investigate the association between MOA or TTH and tactile cognition by utilizing a tactile angle discrimination tester. The results showed that both the MOA and TTH groups exhibited significantly higher tactile angle discrimination thresholds compared to the control group, indicating a decline in tactile discrimination. This decline was particularly evident in young patients. The study suggests a decrease in tactile angle discrimination ability in patients with MOA or TTH, especially those younger than 44 years old. [Extracted from the article]

The article highlights the clinical trial NCT06541106 for vertebrobasilar dissecting aneurysms (VBDAs), launched on August 8, 2024, by Beijing Tiantan Hospital. It also discusses the varied prognosis of VBDAs, the lack of standardized treatment guidelines, and the study's aim to evaluate different treatment modalities and their impact on patient outcomes.

The article offers information on a rare case of chronic headache linked to cerebral venous thrombosis (CVT). Topics discussed include the presentation of symptoms such as headache and papilledema; diagnostic imaging findings including magnetic resonance imaging (MRI) scans indicating dural sinus thrombosis; and the significance of early diagnosis and advanced imaging for managing CVT.

A patent application has been filed for a new method of treating headaches, specifically migraines, using neurotoxins. The current FDA-approved treatment, BOTOX, can have side effects such as muscle weakness and involves multiple injections. The new method aims to simplify the injection process and reduce side effects by targeting specific nerve pathways involved in migraines. The patent application outlines various injection sites and combinations that can be used to enhance the treatment's effectiveness. By avoiding certain areas, the occurrence and severity of side effects can be reduced. The inventors claim that their methods can provide more effective and targeted treatment for migraines and headaches. [Extracted from the article]

A patent application has been filed for a method of treating anxiety disorders, headache disorders, and eating disorders using psilocybin, a compound found in certain mushrooms. The method involves orally administering a therapeutically effective amount of crystalline psilocybin to the patient in the form of a capsule or tablet. The dosage of psilocybin can range from 1 mg to 40 mg, with 25 mg being a common dose. Psychological support sessions are also recommended before and after administration of psilocybin. The patent application provides specific details about the chemical purity and characteristics of the psilocybin used in the method. [Extracted from the article]

Inventor Michael A. Moffitt has filed a patent application for a neurostimulation system that can be used to treat various diseases and disorders. The system includes an implantable pulse generator and a handheld patient programmer that allows for customization of stimulation parameters. Recent research has focused on improving the informational component of the system by delivering non-tonic pulse patterns. The patent application describes an external control device that can customize pulse patterns on a pulse-by-pulse basis and instruct the neurostimulator accordingly. The system also includes memory for storing different customized pulse patterns and the ability to deliver multiple pulse patterns concurrently. [Extracted from the article]