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A total of 20 new indole analogs were synthesized and evaluated for biological activity against Sclerotinia sclerotiorum, Altenaria solani, Verticillium dahliae, Fusarium oxysporum, Pythium walnuts, and Curvularia zea. The preliminary biological testing showed that most of the synthesized compounds exhibited fungicidal activities. Notably, compounds 2 and 7 showed the broadest and most effective activities among the compounds tested and could be potential new lead compounds for the future development of antifungal agents. [ABSTRACT FROM AUTHOR]

Tetrasubstituted imidazoles were synthesized in high yields via the four-component reaction of aromatic aldehydes, amines, substituted benzils and ammonium acetate catalyzed by a porous CeO nanorod. Their anti-cancer activities on the Huh-7 hepatocellular carcinoma cell and antibacterial activities on four bacterial species (wild-type Escherichia coli, wild-type Staphylococcus aureus, Pseudomonas aeruginosa PAM1032 and Escherichia coli-NMD-1) in vitro were evaluated. One compound ( 5p) was screened out because of its high inhibition rate on all four bacterials at 100 μg/mL. Three products ( 5p, 5t and 5y) showed a high inhibition rate on the Huh-7 hepatocellular carcinoma cell at 10 μg/mL. The results indicated their potential in new drug development. [ABSTRACT FROM AUTHOR]

To achieve an efficient visible-light absorption and degradation of bismuth vanadate (BiVO), in this paper, a carbon-doped (C-doped) nanosheets monoclinic BiVO (m-BiVO), with thicknesses within 19.86 ± 8.48 nm, was synthesized using polyvinylpyrrolidone K-30 (PVP) as a template and l-carbonic as the carbon source by one-step hydrothermal synthesis method. This C-doped BiVO in three-dimensional (3D) hierarchical structure enjoys high visible-light photocatalytic property. The samples were characterized using x-ray diffraction, scanning electron microscope, Raman spectra, energy dispersive spectrometer, transmission electron microscope, x-ray photoelectron spectroscopy, UV-Vis diffused reflectance spectroscopy, specific surface area, electron spin resonance, and transient photocurrent response, photoluminescence spectra, and incident-photon-to-current conversion efficiency, respectively. What is more, we studied the C-doping effect on the band-gap energy of BiVO based on First-principles. X-ray diffraction analysis showed that all photocatalysts were in the same single monoclinic scheelite structure. According to the other characterization results, the element C was successfully doped in BiVO, resulting in the 3D hierarchical structure of C-doped BiVO (P-L-BiVO). We speculated that it could be the directional coalescence mechanism by which the l-cysteine promoted the two-dimensional growth and C-doping process of BiVO, thus leading to the formation of nanosheets which were then promoted into 3D self-assembly by PVP and the shortening of the band gap. Among all samples, P-L-BiVO can make the highest removal ratio of rhodamine B under visible-light irradiation. The stability of P-L-BiVO was verified by recycle experiments. It showed that P-L-BiVO had strong visible-light absorption behavior and high electron-hole separation efficiency and stability, making a significant advantage in actual situation. [ABSTRACT FROM AUTHOR]