1. Association Between Biologic Exposure and the Risk of Depression in Patients with Psoriasis: A Retrospective Analysis of Large US Administrative Claims Data.
- Author
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Strober, Bruce, Soliman, Ahmed M., Truong, Bang, Patel, Manish B., Barqawi, Yazan K., and Gisondi, Paolo
- Subjects
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PREVENTION of mental depression , *MENTAL depression risk factors , *RISK assessment , *ANTI-inflammatory agents , *STATISTICAL correlation , *PSORIASIS , *CERTOLIZUMAB pegol , *EARLY medical intervention , *METHOTREXATE , *QUESTIONNAIRES , *BIOLOGICAL products , *ANTIRHEUMATIC agents , *RETROSPECTIVE studies , *DESCRIPTIVE statistics , *MULTIVARIATE analysis , *BIOTHERAPY , *LONGITUDINAL method , *MONOCLONAL antibodies , *ETANERCEPT , *MEDICAL records , *ACQUISITION of data , *ADALIMUMAB , *RESEARCH , *SYNTHETIC drugs , *INFLIXIMAB , *CONFIDENCE intervals , *MENTAL depression , *DISEASE incidence , *INTERLEUKINS , *CYCLOSPORINS , *RETINOIDS , *COMORBIDITY , *MEDICAL care costs , *PROPORTIONAL hazards models - Abstract
The article examines the relationship between biologic treatments for psoriasis and the risk of developing depression, based on a retrospective analysis of U.S. administrative claims data. Topics include the reduced incidence of depression among patients using biologics compared to conventional treatments, the relative risk reduction associated with different classes of biologics, and the implications of these findings for future treatment strategies.
- Published
- 2024
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