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Your search keyword '"Gao, Xiao‐Ling"' showing total 10 results
Start Over Author "Gao, Xiao‐Ling" Publisher springer science and business media llc
10 results on '"Gao, Xiao‐Ling"'

5. Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis

Author

Huang, Jia-Lin, primary, Jiang, Gan, additional, Song, Qing-Xiang, additional, Gu, Xiao, additional, Hu, Meng, additional, Wang, Xiao-Lin, additional, Song, Hua-Hua, additional, Chen, Le-Pei, additional, Lin, Ying-Ying, additional, Jiang, Di, additional, Chen, Jun, additional, Feng, Jun-Feng, additional, Qiu, Yong-Ming, additional, Jiang, Ji-Yao, additional, Jiang, Xin-Guo, additional, Chen, Hong-Zhuan, additional, and Gao, Xiao-Ling, additional

Published
2017
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6. Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats

Author

Zeng Yuan-er, Liu Shuqiang, Li Pingting, Gao Xiao-ling, and Shuling Wang

Subjects
Chronic unpredictable mild stress, Male, medicine.medical_specialty, Clinical chemistry, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Clinical nutrition, Biology, Diet, High-Fat, Cholesterol 7 alpha-hydroxylase, Rats, Sprague-Dawley, chemistry.chemical_compound, Endocrinology, Stress, Physiological, Internal medicine, medicine, Animals, Chronic stress, Biochemistry, medical, Cholesterol, Research, Biochemistry (medical), Reverse cholesterol transport, Biological Transport, Lipid metabolism, Atherosclerosis, Rats, High-fat diet, chemistry, Lipidology
Abstract

Background Depression and high-fat diet are both known as independent risk factors for atherosclerosis and other cardiovascular diseases, suggesting the interaction of psychological and physiological factors in the development of these diseases. The liver is a crucial organ that facilitate lipid metabolism especially in reverse cholesterol transport (RCT), while according to the theory of Traditional Chinese Medicine, depression as a kind of psychological stress has an influence on hepatic function. So there seem to be some links between depression and lipid metabolic disorders. Methods To investigate these links, we separately treated rats with chronic unpredictable mild stress (CMS) and/or a high-fat diet (HD) to evaluate the development of atherosclerosis and the expression of hepatic ABCG8, ABCG5, SR-BI, CYP7A1, LXRα, and LCAT which were associated with reverse cholesterol transport. Results This study provided evidence that high-fat diet greatly decreased these genes expression related to RCT while chronic stress alone tended to promote RCT. Chronic unpredictable mild stress combined with a high-fat diet attenuated RCT and aggravated atherogenesis. Conclusions These observations suggested that chronic psychological stress alone is virtually propitious to lipid metabolism, however when under a condition of high-fat diet, it deteriorated atherosclerotic plague and did harm to RCT.

Published
2014

9. Synthesis and evaluation of κ-opioid receptor agonistic activity and antinociceptive effect of novel morphine analogues, 7α-phenyl-6α,14α-endo-etheno-tetrahydrothebaine with substituted o-, m- and p-amino group

Author

Qi, Hong, primary, Li, Wei, additional, Qiu, Yu, additional, Cui, Yong-yao, additional, Ma, Jian, additional, Gao, Xiao-ling, additional, Zeng, Yi-bin, additional, Yang, Jie, additional, Tang, Yun, additional, Wang, Xing-hai, additional, Sheng, Wei, additional, Xie, Qiong, additional, Liu, Jing-geng, additional, Qiu, Zhui-bai, additional, and Chen, Hong-zhuan, additional

Published
2010
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