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220 results on '"Giles, Graham G."'

1. Self-rated health, epigenetic ageing, and long-term mortality in older Australians

Author: Li, Danmeng Lily, primary, Hodge, Allison M., additional, Southey, Melissa C., additional, Giles, Graham G., additional, Milne, Roger L., additional, and Dugué, Pierre-Antoine, additional
Published: 2024
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2. Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Author: Chen, Zhishan, primary, Guo, Xingyi, additional, Tao, Ran, additional, Huyghe, Jeroen R., additional, Law, Philip J., additional, Fernandez-Rozadilla, Ceres, additional, Ping, Jie, additional, Jia, Guochong, additional, Long, Jirong, additional, Li, Chao, additional, Shen, Quanhu, additional, Xie, Yuhan, additional, Timofeeva, Maria N., additional, Thomas, Minta, additional, Schmit, Stephanie L., additional, Díez-Obrero, Virginia, additional, Devall, Matthew, additional, Moratalla-Navarro, Ferran, additional, Fernandez-Tajes, Juan, additional, Palles, Claire, additional, Sherwood, Kitty, additional, Briggs, Sarah E. W., additional, Svinti, Victoria, additional, Donnelly, Kevin, additional, Farrington, Susan M., additional, Blackmur, James, additional, Vaughan-Shaw, Peter G., additional, Shu, Xiao-Ou, additional, Lu, Yingchang, additional, Broderick, Peter, additional, Studd, James, additional, Harrison, Tabitha A., additional, Conti, David V., additional, Schumacher, Fredrick R., additional, Melas, Marilena, additional, Rennert, Gad, additional, Obón-Santacana, Mireia, additional, Martín-Sánchez, Vicente, additional, Oh, Jae Hwan, additional, Kim, Jeongseon, additional, Jee, Sun Ha, additional, Jung, Keum Ji, additional, Kweon, Sun-Seog, additional, Shin, Min-Ho, additional, Shin, Aesun, additional, Ahn, Yoon-Ok, additional, Kim, Dong-Hyun, additional, Oze, Isao, additional, Wen, Wanqing, additional, Matsuo, Keitaro, additional, Matsuda, Koichi, additional, Tanikawa, Chizu, additional, Ren, Zefang, additional, Gao, Yu-Tang, additional, Jia, Wei-Hua, additional, Hopper, John L., additional, Jenkins, Mark A., additional, Win, Aung Ko, additional, Pai, Rish K., additional, Figueiredo, Jane C., additional, Haile, Robert W., additional, Gallinger, Steven, additional, Woods, Michael O., additional, Newcomb, Polly A., additional, Duggan, David, additional, Cheadle, Jeremy P., additional, Kaplan, Richard, additional, Kerr, Rachel, additional, Kerr, David, additional, Kirac, Iva, additional, Böhm, Jan, additional, Mecklin, Jukka-Pekka, additional, Jousilahti, Pekka, additional, Knekt, Paul, additional, Aaltonen, Lauri A., additional, Rissanen, Harri, additional, Pukkala, Eero, additional, Eriksson, Johan G., additional, Cajuso, Tatiana, additional, Hänninen, Ulrika, additional, Kondelin, Johanna, additional, Palin, Kimmo, additional, Tanskanen, Tomas, additional, Renkonen-Sinisalo, Laura, additional, Männistö, Satu, additional, Albanes, Demetrius, additional, Weinstein, Stephanie J., additional, Ruiz-Narvaez, Edward, additional, Palmer, Julie R., additional, Buchanan, Daniel D., additional, Platz, Elizabeth A., additional, Visvanathan, Kala, additional, Ulrich, Cornelia M., additional, Siegel, Erin, additional, Brezina, Stefanie, additional, Gsur, Andrea, additional, Campbell, Peter T., additional, Chang-Claude, Jenny, additional, Hoffmeister, Michael, additional, Brenner, Hermann, additional, Slattery, Martha L., additional, Potter, John D., additional, Tsilidis, Kostas K., additional, Schulze, Matthias B., additional, Gunter, Marc J., additional, Murphy, Neil, additional, Castells, Antoni, additional, Castellví-Bel, Sergi, additional, Moreira, Leticia, additional, Arndt, Volker, additional, Shcherbina, Anna, additional, Bishop, D. Timothy, additional, Giles, Graham G., additional, Southey, Melissa C., additional, Idos, Gregory E., additional, McDonnell, Kevin J., additional, Abu-Ful, Zomoroda, additional, Greenson, Joel K., additional, Shulman, Katerina, additional, Lejbkowicz, Flavio, additional, Offit, Kenneth, additional, Su, Yu-Ru, additional, Steinfelder, Robert, additional, Keku, Temitope O., additional, van Guelpen, Bethany, additional, Hudson, Thomas J., additional, Hampel, Heather, additional, Pearlman, Rachel, additional, Berndt, Sonja I., additional, Hayes, Richard B., additional, Martinez, Marie Elena, additional, Thomas, Sushma S., additional, Pharoah, Paul D. P., additional, Larsson, Susanna C., additional, Yen, Yun, additional, Lenz, Heinz-Josef, additional, White, Emily, additional, Li, Li, additional, Doheny, Kimberly F., additional, Pugh, Elizabeth, additional, Shelford, Tameka, additional, Chan, Andrew T., additional, Cruz-Correa, Marcia, additional, Lindblom, Annika, additional, Hunter, David J., additional, Joshi, Amit D., additional, Schafmayer, Clemens, additional, Scacheri, Peter C., additional, Kundaje, Anshul, additional, Schoen, Robert E., additional, Hampe, Jochen, additional, Stadler, Zsofia K., additional, Vodicka, Pavel, additional, Vodickova, Ludmila, additional, Vymetalkova, Veronika, additional, Edlund, Christopher K., additional, Gauderman, W. James, additional, Shibata, David, additional, Toland, Amanda, additional, Markowitz, Sanford, additional, Kim, Andre, additional, Chanock, Stephen J., additional, van Duijnhoven, Franzel, additional, Feskens, Edith J. M., additional, Sakoda, Lori C., additional, Gago-Dominguez, Manuela, additional, Wolk, Alicja, additional, Pardini, Barbara, additional, FitzGerald, Liesel M., additional, Lee, Soo Chin, additional, Ogino, Shuji, additional, Bien, Stephanie A., additional, Kooperberg, Charles, additional, Li, Christopher I., additional, Lin, Yi, additional, Prentice, Ross, additional, Qu, Conghui, additional, Bézieau, Stéphane, additional, Yamaji, Taiki, additional, Sawada, Norie, additional, Iwasaki, Motoki, additional, Le Marchand, Loic, additional, Wu, Anna H., additional, Qu, Chenxu, additional, McNeil, Caroline E., additional, Coetzee, Gerhard, additional, Hayward, Caroline, additional, Deary, Ian J., additional, Harris, Sarah E., additional, Theodoratou, Evropi, additional, Reid, Stuart, additional, Walker, Marion, additional, Ooi, Li Yin, additional, Lau, Ken S., additional, Zhao, Hongyu, additional, Hsu, Li, additional, Cai, Qiuyin, additional, Dunlop, Malcolm G., additional, Gruber, Stephen B., additional, Houlston, Richard S., additional, Moreno, Victor, additional, Casey, Graham, additional, Peters, Ulrike, additional, Tomlinson, Ian, additional, and Zheng, Wei, additional
Published: 2024
Full Text: View/download PDF

3. Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk

Author: Tian, Yu, primary, Lin, Yi, additional, Qu, Conghui, additional, Arndt, Volker, additional, Baurley, James W., additional, Berndt, Sonja I., additional, Bien, Stephanie A., additional, Bishop, D. Timothy, additional, Brenner, Hermann, additional, Buchanan, Daniel D., additional, Budiarto, Arif, additional, Campbell, Peter T., additional, Carreras-Torres, Robert, additional, Casey, Graham, additional, Chan, Andrew T., additional, Chen, Rui, additional, Chen, Xuechen, additional, Conti, David V., additional, Díez-Obrero, Virginia, additional, Dimou, Niki, additional, Drew, David A., additional, Figueiredo, Jane C., additional, Gallinger, Steven, additional, Giles, Graham G., additional, Gruber, Stephen B., additional, Gunter, Marc J., additional, Harlid, Sophia, additional, Harrison, Tabitha A., additional, Hidaka, Akihisa, additional, Hoffmeister, Michael, additional, Huyghe, Jeroen R., additional, Jenkins, Mark A., additional, Jordahl, Kristina M., additional, Joshi, Amit D., additional, Keku, Temitope O., additional, Kawaguchi, Eric, additional, Kim, Andre E., additional, Kundaje, Anshul, additional, Larsson, Susanna C., additional, Marchand, Loic Le, additional, Lewinger, Juan Pablo, additional, Li, Li, additional, Moreno, Victor, additional, Morrison, John, additional, Murphy, Neil, additional, Nan, Hongmei, additional, Nassir, Rami, additional, Newcomb, Polly A., additional, Obón-Santacana, Mireia, additional, Ogino, Shuji, additional, Ose, Jennifer, additional, Pardamean, Bens, additional, Pellatt, Andrew J., additional, Peoples, Anita R., additional, Platz, Elizabeth A., additional, Potter, John D., additional, Prentice, Ross L., additional, Rennert, Gad, additional, Ruiz-Narvaez, Edward A., additional, Sakoda, Lori C., additional, Schoen, Robert E., additional, Shcherbina, Anna, additional, Stern, Mariana C., additional, Su, Yu-Ru, additional, Thibodeau, Stephen N., additional, Thomas, Duncan C., additional, Tsilidis, Konstantinos K., additional, van Duijnhoven, Franzel J. B., additional, Van Guelpen, Bethany, additional, Visvanathan, Kala, additional, White, Emily, additional, Wolk, Alicja, additional, Woods, Michael O., additional, Wu, Anna H., additional, Peters, Ulrike, additional, Gauderman, W. James, additional, Hsu, Li, additional, and Chang-Claude, Jenny, additional
Published: 2024
Full Text: View/download PDF

4. Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Author: Thomas, Minta, primary, Su, Yu-Ru, additional, Rosenthal, Elisabeth A., additional, Sakoda, Lori C., additional, Schmit, Stephanie L., additional, Timofeeva, Maria N., additional, Chen, Zhishan, additional, Fernandez-Rozadilla, Ceres, additional, Law, Philip J., additional, Murphy, Neil, additional, Carreras-Torres, Robert, additional, Diez-Obrero, Virginia, additional, van Duijnhoven, Franzel J. B., additional, Jiang, Shangqing, additional, Shin, Aesun, additional, Wolk, Alicja, additional, Phipps, Amanda I., additional, Burnett-Hartman, Andrea, additional, Gsur, Andrea, additional, Chan, Andrew T., additional, Zauber, Ann G., additional, Wu, Anna H., additional, Lindblom, Annika, additional, Um, Caroline Y., additional, Tangen, Catherine M., additional, Gignoux, Chris, additional, Newton, Christina, additional, Haiman, Christopher A., additional, Qu, Conghui, additional, Bishop, D. Timothy, additional, Buchanan, Daniel D., additional, Crosslin, David R., additional, Conti, David V., additional, Kim, Dong-Hyun, additional, Hauser, Elizabeth, additional, White, Emily, additional, Siegel, Erin, additional, Schumacher, Fredrick R., additional, Rennert, Gad, additional, Giles, Graham G., additional, Hampel, Heather, additional, Brenner, Hermann, additional, Oze, Isao, additional, Oh, Jae Hwan, additional, Lee, Jeffrey K., additional, Schneider, Jennifer L., additional, Chang-Claude, Jenny, additional, Kim, Jeongseon, additional, Huyghe, Jeroen R., additional, Zheng, Jiayin, additional, Hampe, Jochen, additional, Greenson, Joel, additional, Hopper, John L., additional, Palmer, Julie R., additional, Visvanathan, Kala, additional, Matsuo, Keitaro, additional, Matsuda, Koichi, additional, Jung, Keum Ji, additional, Li, Li, additional, Le Marchand, Loic, additional, Vodickova, Ludmila, additional, Bujanda, Luis, additional, Gunter, Marc J., additional, Matejcic, Marco, additional, Jenkins, Mark A., additional, Slattery, Martha L., additional, D’Amato, Mauro, additional, Wang, Meilin, additional, Hoffmeister, Michael, additional, Woods, Michael O., additional, Kim, Michelle, additional, Song, Mingyang, additional, Iwasaki, Motoki, additional, Du, Mulong, additional, Udaltsova, Natalia, additional, Sawada, Norie, additional, Vodicka, Pavel, additional, Campbell, Peter T., additional, Newcomb, Polly A., additional, Cai, Qiuyin, additional, Pearlman, Rachel, additional, Pai, Rish K., additional, Schoen, Robert E., additional, Steinfelder, Robert S., additional, Haile, Robert W., additional, Vandenputtelaar, Rosita, additional, Prentice, Ross L., additional, Küry, Sébastien, additional, Castellví-Bel, Sergi, additional, Tsugane, Shoichiro, additional, Berndt, Sonja I., additional, Lee, Soo Chin, additional, Brezina, Stefanie, additional, Weinstein, Stephanie J., additional, Chanock, Stephen J., additional, Jee, Sun Ha, additional, Kweon, Sun-Seog, additional, Vadaparampil, Susan, additional, Harrison, Tabitha A., additional, Yamaji, Taiki, additional, Keku, Temitope O., additional, Vymetalkova, Veronika, additional, Arndt, Volker, additional, Jia, Wei-Hua, additional, Shu, Xiao-Ou, additional, Lin, Yi, additional, Ahn, Yoon-Ok, additional, Stadler, Zsofia K., additional, Van Guelpen, Bethany, additional, Ulrich, Cornelia M., additional, Platz, Elizabeth A., additional, Potter, John D., additional, Li, Christopher I., additional, Meester, Reinier, additional, Moreno, Victor, additional, Figueiredo, Jane C., additional, Casey, Graham, additional, Lansdorp Vogelaar, Iris, additional, Dunlop, Malcolm G., additional, Gruber, Stephen B., additional, Hayes, Richard B., additional, Pharoah, Paul D. P., additional, Houlston, Richard S., additional, Jarvik, Gail P., additional, Tomlinson, Ian P., additional, Zheng, Wei, additional, Corley, Douglas A., additional, Peters, Ulrike, additional, and Hsu, Li, additional
Published: 2023
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5. Identification of novel genetic loci for risk of multiple myeloma by functional annotation

Author: Macauda, Angelica, primary, Briem, Klara, additional, Clay-Gilmour, Alyssa, additional, Cozen, Wendy, additional, Försti, Asta, additional, Giaccherini, Matteo, additional, Corradi, Chiara, additional, Sainz, Juan, additional, Niazi, Yasmeen, additional, ter Horst, Rob, additional, Li, Yang, additional, Netea, Mihai G., additional, Vogel, Ulla, additional, Hemminki, Kari, additional, Slager, Susan L., additional, Varkonyi, Judit, additional, Andersen, Vibeke, additional, Iskierka-Jazdzewska, Elzbieta, additional, Mártinez-Lopez, Joaquin, additional, Zaucha, Jan, additional, Camp, Nicola J., additional, Rajkumar, S. Vincent, additional, Druzd-Sitek, Agnieszka, additional, Bhatti, Parveen, additional, Chanock, Stephen J., additional, Kumar, Shaji K., additional, Subocz, Edyta, additional, Mazur, Grzegorz, additional, Landi, Stefano, additional, Machiela, Mitchell J., additional, Jerez, Andrés, additional, Norman, Aaron D., additional, Hildebrandt, Michelle A. T., additional, Kadar, Katalin, additional, Berndt, Sonja I., additional, Ziv, Elad, additional, Buda, Gabriele, additional, Nagler, Arnon, additional, Dumontet, Charles, additional, Raźny, Malgorzata, additional, Watek, Marzena, additional, Butrym, Aleksandra, additional, Grzasko, Norbert, additional, Dudzinski, Marek, additional, Rybicka-Ramos, Malwina, additional, Matera, Eva-Laure, additional, García-Sanz, Ramón, additional, Goldschmidt, Hartmut, additional, Jamroziak, Krzysztof, additional, Jurczyszyn, Artur, additional, Clavero, Esther, additional, Giles, Graham G., additional, Pelosini, Matteo, additional, Zawirska, Daria, additional, Kruszewski, Marcin, additional, Marques, Herlander, additional, Haastrup, Eva, additional, Sánchez-Maldonado, José Manuel, additional, Bertsch, Uta, additional, Rymko, Marcin, additional, Raab, Marc-Steffen, additional, Brown, Elizabeth E., additional, Hofmann, Jonathan N., additional, Vachon, Celine, additional, Campa, Daniele, additional, and Canzian, Federico, additional
Published: 2023
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6. Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes

Author: Berndt, Sonja I., primary, Vijai, Joseph, additional, Benavente, Yolanda, additional, Camp, Nicola J., additional, Nieters, Alexandra, additional, Wang, Zhaoming, additional, Smedby, Karin E., additional, Kleinstern, Geffen, additional, Hjalgrim, Henrik, additional, Besson, Caroline, additional, Skibola, Christine F., additional, Morton, Lindsay M., additional, Brooks-Wilson, Angela R., additional, Teras, Lauren R., additional, Breeze, Charles, additional, Arias, Joshua, additional, Adami, Hans-Olov, additional, Albanes, Demetrius, additional, Anderson, Kenneth C., additional, Ansell, Stephen M., additional, Bassig, Bryan, additional, Becker, Nikolaus, additional, Bhatti, Parveen, additional, Birmann, Brenda M., additional, Boffetta, Paolo, additional, Bracci, Paige M., additional, Brennan, Paul, additional, Brown, Elizabeth E., additional, Burdett, Laurie, additional, Cannon-Albright, Lisa A., additional, Chang, Ellen T., additional, Chiu, Brian C. H., additional, Chung, Charles C., additional, Clavel, Jacqueline, additional, Cocco, Pierluigi, additional, Colditz, Graham, additional, Conde, Lucia, additional, Conti, David V., additional, Cox, David G., additional, Curtin, Karen, additional, Casabonne, Delphine, additional, De Vivo, Immaculata, additional, Diepstra, Arjan, additional, Diver, W. Ryan, additional, Dogan, Ahmet, additional, Edlund, Christopher K., additional, Foretova, Lenka, additional, Fraumeni, Joseph F., additional, Gabbas, Attilio, additional, Ghesquières, Hervé, additional, Giles, Graham G., additional, Glaser, Sally, additional, Glenn, Martha, additional, Glimelius, Bengt, additional, Gu, Jian, additional, Habermann, Thomas M., additional, Haiman, Christopher A., additional, Haioun, Corinne, additional, Hofmann, Jonathan N., additional, Holford, Theodore R., additional, Holly, Elizabeth A., additional, Hutchinson, Amy, additional, Izhar, Aalin, additional, Jackson, Rebecca D., additional, Jarrett, Ruth F., additional, Kaaks, Rudolph, additional, Kane, Eleanor, additional, Kolonel, Laurence N., additional, Kong, Yinfei, additional, Kraft, Peter, additional, Kricker, Anne, additional, Lake, Annette, additional, Lan, Qing, additional, Lawrence, Charles, additional, Li, Dalin, additional, Liebow, Mark, additional, Link, Brian K., additional, Magnani, Corrado, additional, Maynadie, Marc, additional, McKay, James, additional, Melbye, Mads, additional, Miligi, Lucia, additional, Milne, Roger L., additional, Molina, Thierry J., additional, Monnereau, Alain, additional, Montalvan, Rebecca, additional, North, Kari E., additional, Novak, Anne J., additional, Onel, Kenan, additional, Purdue, Mark P., additional, Rand, Kristin A., additional, Riboli, Elio, additional, Riby, Jacques, additional, Roman, Eve, additional, Salles, Gilles, additional, Sborov, Douglas W., additional, Severson, Richard K., additional, Shanafelt, Tait D., additional, Smith, Martyn T., additional, Smith, Alexandra, additional, Song, Kevin W., additional, Song, Lei, additional, Southey, Melissa C., additional, Spinelli, John J., additional, Staines, Anthony, additional, Stephens, Deborah, additional, Sutherland, Heather J., additional, Tkachuk, Kaitlyn, additional, Thompson, Carrie A., additional, Tilly, Hervé, additional, Tinker, Lesley F., additional, Travis, Ruth C., additional, Turner, Jenny, additional, Vachon, Celine M., additional, Vajdic, Claire M., additional, Van Den Berg, Anke, additional, Van Den Berg, David J., additional, Vermeulen, Roel C. H., additional, Vineis, Paolo, additional, Wang, Sophia S., additional, Weiderpass, Elisabete, additional, Weiner, George J., additional, Weinstein, Stephanie, additional, Doo, Nicole Wong, additional, Ye, Yuanqing, additional, Yeager, Meredith, additional, Yu, Kai, additional, Zeleniuch-Jacquotte, Anne, additional, Zhang, Yawei, additional, Zheng, Tongzhang, additional, Ziv, Elad, additional, Sampson, Joshua, additional, Chatterjee, Nilanjan, additional, Offit, Kenneth, additional, Cozen, Wendy, additional, Wu, Xifeng, additional, Cerhan, James R., additional, Chanock, Stephen J., additional, Slager, Susan L., additional, and Rothman, Nathaniel, additional
Published: 2023
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7. Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses

Author: Dimou, Niki, primary, Kim, Andre E., additional, Flanagan, Orlagh, additional, Murphy, Neil, additional, Diez-Obrero, Virginia, additional, Shcherbina, Anna, additional, Aglago, Elom K., additional, Bouras, Emmanouil, additional, Campbell, Peter T., additional, Casey, Graham, additional, Gallinger, Steven, additional, Gruber, Stephen B., additional, Jenkins, Mark A., additional, Lin, Yi, additional, Moreno, Victor, additional, Ruiz-Narvaez, Edward, additional, Stern, Mariana C., additional, Tian, Yu, additional, Tsilidis, Kostas K., additional, Arndt, Volker, additional, Barry, Elizabeth L., additional, Baurley, James W., additional, Berndt, Sonja I., additional, Bézieau, Stéphane, additional, Bien, Stephanie A., additional, Bishop, D. Timothy, additional, Brenner, Hermann, additional, Budiarto, Arif, additional, Carreras-Torres, Robert, additional, Cenggoro, Tjeng Wawan, additional, Chan, Andrew T., additional, Chang-Claude, Jenny, additional, Chanock, Stephen J., additional, Chen, Xuechen, additional, Conti, David V., additional, Dampier, Christopher H., additional, Devall, Matthew, additional, Drew, David A., additional, Figueiredo, Jane C., additional, Giles, Graham G., additional, Gsur, Andrea, additional, Harrison, Tabitha A., additional, Hidaka, Akihisa, additional, Hoffmeister, Michael, additional, Huyghe, Jeroen R., additional, Jordahl, Kristina, additional, Kawaguchi, Eric, additional, Keku, Temitope O., additional, Larsson, Susanna C., additional, Le Marchand, Loic, additional, Lewinger, Juan Pablo, additional, Li, Li, additional, Mahesworo, Bharuno, additional, Morrison, John, additional, Newcomb, Polly A., additional, Newton, Christina C., additional, Obon-Santacana, Mireia, additional, Ose, Jennifer, additional, Pai, Rish K., additional, Palmer, Julie R., additional, Papadimitriou, Nikos, additional, Pardamean, Bens, additional, Peoples, Anita R., additional, Pharoah, Paul D. P., additional, Platz, Elizabeth A., additional, Potter, John D., additional, Rennert, Gad, additional, Scacheri, Peter C., additional, Schoen, Robert E., additional, Su, Yu-Ru, additional, Tangen, Catherine M., additional, Thibodeau, Stephen N., additional, Thomas, Duncan C., additional, Ulrich, Cornelia M., additional, Um, Caroline Y., additional, van Duijnhoven, Franzel J. B., additional, Visvanathan, Kala, additional, Vodicka, Pavel, additional, Vodickova, Ludmila, additional, White, Emily, additional, Wolk, Alicja, additional, Woods, Michael O., additional, Qu, Conghui, additional, Kundaje, Anshul, additional, Hsu, Li, additional, Gauderman, W. James, additional, Gunter, Marc J., additional, and Peters, Ulrike, additional
Published: 2023
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8. Estimated dietary intake of polyphenols from cereal foods and associated lifestyle and demographic factors in the Melbourne Collaborative Cohort Study

Author: Vingrys, Kristina, primary, Mathai, Michael L., additional, Apostolopoulos, Vasso, additional, Bassett, Julie K., additional, de Courten, Maximilian, additional, Stojanovska, Lily, additional, Millar, Lynne, additional, Giles, Graham G., additional, Milne, Roger L., additional, Hodge, Allison M., additional, and McAinch, Andrew J., additional
Published: 2023
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9. Estrogen receptor beta expression in triple negative breast cancers is not associated with recurrence or survival

Author: Takano, Elena A., primary, Younes, Melissa M., additional, Meehan, Katie, additional, Spalding, Lisa, additional, Yan, Max, additional, Allan, Prue, additional, Fox, Stephen B., additional, Redfern, Andy, additional, Clouston, David, additional, Giles, Graham G., additional, Christie, Elizabeth L., additional, Anderson, Robin L., additional, Zethoven, Magnus, additional, Phillips, Kelly-Anne, additional, Gorringe, Kylie, additional, and Britt, Kara L., additional
Published: 2023
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10. Hypertensive conditions of pregnancy, preterm birth, and premenopausal breast cancer risk: a premenopausal breast cancer collaborative group analysis

Author: Nichols, Hazel B., primary, House, Melissa G., additional, Yarosh, Rina, additional, Mitra, Sara, additional, Goldberg, Mandy, additional, Bertrand, Kimberly A., additional, Eliassen, A. Heather, additional, Giles, Graham G., additional, Jones, Michael E., additional, Milne, Roger L., additional, O’Brien, Katie M., additional, Palmer, Julie R., additional, Sandin, Sven, additional, Willett, Walter C., additional, Yin, Weiyao, additional, Sandler, Dale P., additional, Swerdlow, Anthony J., additional, and Schoemaker, Minouk J., additional
Published: 2023
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11. Heritable methylation marks associated with prostate cancer risk

Author: Dowty, James G., primary, Yu, Chenglong, additional, Hosseinpour, Mahnaz, additional, Joo, Jihoon Eric, additional, Wong, Ee Ming, additional, Nguyen-Dumont, Tu, additional, Rosenbluh, Joseph, additional, Giles, Graham G., additional, Milne, Roger L., additional, MacInnis, Robert J., additional, Dugué, Pierre-Antoine, additional, and Southey, Melissa C., additional
Published: 2023
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12. A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium

Author: Midttun, Øivind, primary, Ulvik, Arve, additional, Meyer, Klaus, additional, Zahed, Hana, additional, Giles, Graham G., additional, Manjer, Jonas, additional, Sandsveden, Malte, additional, Langhammer, Arnulf, additional, Sørgjerd, Elin Pettersen, additional, Behndig, Annelie F., additional, Johansson, Mikael, additional, Freedman, Neal D., additional, Huang, Wen-Yi, additional, Chen, Chu, additional, Prentice, Ross, additional, Stevens, Victoria L., additional, Wang, Ying, additional, Le Marchand, Loïc, additional, Weinstein, Stephanie J., additional, Cai, Qiuyin, additional, Arslan, Alan A., additional, Chen, Yu, additional, Shu, Xiao-Ou, additional, Zheng, Wei, additional, Yuan, Jian-Min, additional, Koh, Woon-Puay, additional, Visvanathan, Kala, additional, Sesso, Howard D., additional, Zhang, Xuehong, additional, Gaziano, J. Michael, additional, Fanidi, Anouar, additional, Robbins, Hilary A., additional, Brennan, Paul, additional, Johansson, Mattias, additional, and Ueland, Per M., additional
Published: 2023
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13. Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk

Author: Haas, Cameron B., primary, Su, Yu-Ru, additional, Petersen, Paneen, additional, Wang, Xiaoliang, additional, Bien, Stephanie A., additional, Lin, Yi, additional, Albanes, Demetrius, additional, Weinstein, Stephanie J., additional, Jenkins, Mark A., additional, Figueiredo, Jane C., additional, Newcomb, Polly A., additional, Casey, Graham, additional, Le Marchand, Loic, additional, Campbell, Peter T., additional, Moreno, Victor, additional, Potter, John D., additional, Sakoda, Lori C., additional, Slattery, Martha L., additional, Chan, Andrew T., additional, Li, Li, additional, Giles, Graham G., additional, Milne, Roger L., additional, Gruber, Stephen B., additional, Rennert, Gad, additional, Woods, Michael O., additional, Gallinger, Steven J., additional, Berndt, Sonja, additional, Hayes, Richard B., additional, Huang, Wen-Yi, additional, Wolk, Alicja, additional, White, Emily, additional, Nan, Hongmei, additional, Nassir, Rami, additional, Lindor, Noralane M., additional, Lewinger, Juan P., additional, Kim, Andre E., additional, Conti, David, additional, Gauderman, W. James, additional, Buchanan, Daniel D., additional, Peters, Ulrike, additional, and Hsu, Li, additional
Published: 2022
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14. Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes

Author: Berndt, Sonja I., primary, Vijai, Joseph, additional, Benavente, Yolanda, additional, Camp, Nicola J., additional, Nieters, Alexandra, additional, Wang, Zhaoming, additional, Smedby, Karin E., additional, Kleinstern, Geffen, additional, Hjalgrim, Henrik, additional, Besson, Caroline, additional, Skibola, Christine F., additional, Morton, Lindsay M., additional, Brooks-Wilson, Angela R., additional, Teras, Lauren R., additional, Breeze, Charles, additional, Arias, Joshua, additional, Adami, Hans-Olov, additional, Albanes, Demetrius, additional, Anderson, Kenneth C., additional, Ansell, Stephen M., additional, Bassig, Bryan, additional, Becker, Nikolaus, additional, Bhatti, Parveen, additional, Birmann, Brenda M., additional, Boffetta, Paolo, additional, Bracci, Paige M., additional, Brennan, Paul, additional, Brown, Elizabeth E., additional, Burdett, Laurie, additional, Cannon-Albright, Lisa A., additional, Chang, Ellen T., additional, Chiu, Brian C. H., additional, Chung, Charles C., additional, Clavel, Jacqueline, additional, Cocco, Pierluigi, additional, Colditz, Graham, additional, Conde, Lucia, additional, Conti, David V., additional, Cox, David G., additional, Curtin, Karen, additional, Casabonne, Delphine, additional, De Vivo, Immaculata, additional, Diepstra, Arjan, additional, Diver, W. Ryan, additional, Dogan, Ahmet, additional, Edlund, Christopher K., additional, Foretova, Lenka, additional, Fraumeni, Joseph F., additional, Gabbas, Attilio, additional, Ghesquières, Hervé, additional, Giles, Graham G., additional, Glaser, Sally, additional, Glenn, Martha, additional, Glimelius, Bengt, additional, Gu, Jian, additional, Habermann, Thomas M., additional, Haiman, Christopher A., additional, Haioun, Corinne, additional, Hofmann, Jonathan N., additional, Holford, Theodore R., additional, Holly, Elizabeth A., additional, Hutchinson, Amy, additional, Izhar, Aalin, additional, Jackson, Rebecca D., additional, Jarrett, Ruth F., additional, Kaaks, Rudolph, additional, Kane, Eleanor, additional, Kolonel, Laurence N., additional, Kong, Yinfei, additional, Kraft, Peter, additional, Kricker, Anne, additional, Lake, Annette, additional, Lan, Qing, additional, Lawrence, Charles, additional, Li, Dalin, additional, Liebow, Mark, additional, Link, Brian K., additional, Magnani, Corrado, additional, Maynadie, Marc, additional, McKay, James, additional, Melbye, Mads, additional, Miligi, Lucia, additional, Milne, Roger L., additional, Molina, Thierry J., additional, Monnereau, Alain, additional, Montalvan, Rebecca, additional, North, Kari E., additional, Novak, Anne J., additional, Onel, Kenan, additional, Purdue, Mark P., additional, Rand, Kristin A., additional, Riboli, Elio, additional, Riby, Jacques, additional, Roman, Eve, additional, Salles, Gilles, additional, Sborov, Douglas W., additional, Severson, Richard K., additional, Shanafelt, Tait D., additional, Smith, Martyn T., additional, Smith, Alexandra, additional, Song, Kevin W., additional, Song, Lei, additional, Southey, Melissa C., additional, Spinelli, John J., additional, Staines, Anthony, additional, Stephens, Deborah, additional, Sutherland, Heather J., additional, Tkachuk, Kaitlyn, additional, Thompson, Carrie A., additional, Tilly, Hervé, additional, Tinker, Lesley F., additional, Travis, Ruth C., additional, Turner, Jenny, additional, Vachon, Celine M., additional, Vajdic, Claire M., additional, Van Den Berg, Anke, additional, Van Den Berg, David J., additional, Vermeulen, Roel C. H., additional, Vineis, Paolo, additional, Wang, Sophia S., additional, Weiderpass, Elisabete, additional, Weiner, George J., additional, Weinstein, Stephanie, additional, Doo, Nicole Wong, additional, Ye, Yuanqing, additional, Yeager, Meredith, additional, Yu, Kai, additional, Zeleniuch-Jacquotte, Anne, additional, Zhang, Yawei, additional, Zheng, Tongzhang, additional, Ziv, Elad, additional, Sampson, Joshua, additional, Chatterjee, Nilanjan, additional, Offit, Kenneth, additional, Cozen, Wendy, additional, Wu, Xifeng, additional, Cerhan, James R., additional, Chanock, Stephen J., additional, Slager, Susan L., additional, and Rothman, Nathaniel, additional
Published: 2022
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15. Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies

Author: Dugué, Pierre-Antoine, primary, Bodelon, Clara, additional, Chung, Felicia F., additional, Brewer, Hannah R., additional, Ambatipudi, Srikant, additional, Sampson, Joshua N., additional, Cuenin, Cyrille, additional, Chajès, Veronique, additional, Romieu, Isabelle, additional, Fiorito, Giovanni, additional, Sacerdote, Carlotta, additional, Krogh, Vittorio, additional, Panico, Salvatore, additional, Tumino, Rosario, additional, Vineis, Paolo, additional, Polidoro, Silvia, additional, Baglietto, Laura, additional, English, Dallas, additional, Severi, Gianluca, additional, Giles, Graham G., additional, Milne, Roger L., additional, Herceg, Zdenko, additional, Garcia-Closas, Montserrat, additional, Flanagan, James M., additional, and Southey, Melissa C., additional
Published: 2022
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16. Rare germline copy number variants (CNVs) and breast cancer risk

Author: Dennis, Joe, Tyrer, Jonathan, Walker, Logan C, Michailidou, Kyriaki, Dorling, Leila, Bolla, Manjeet K, Wang, Jean, Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Aronson, Kristan J, Freeman, Laura E Beane, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bogdanova, Natalia V, Bojesen, Stig E, Brenner, Hermann, Castelao, Jose E, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Clarke, Christine L, Kristensen, Vessela N, Sahlberg, Kristine K, Børresen-Dale, Anne-Lise, Gram, Inger Torhild, Engebråten, Olav, Naume, Bjørn, Geisler, Jürgen, Alnæs, Grethe I Grenaker, Collée, J Margriet, Lacey, James, Martinez, Elena, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Devilee, Peter, Dörk, Thilo, Dossus, Laure, Eliassen, A Heather, Eriksson, Mikael, Evans, D Gareth, Fasching, Peter A, Figueroa, Jonine, Fletcher, Olivia, Flyger, Henrik, Fritschi, Lin, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, Giles, Graham G, González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A, Hall, Per, Hollestelle, Antoinette, Hoppe, Reiner, Hopper, John L, Howell, Anthony, Clarke, Christine, Carpenter, Jane, Marsh, Deborah, Scott, Rodney, Baxter, Robert, Yip, Desmond, Davis, Alison, Pathmanathan, Nirmala, Simpson, Peter, Graham, Dinny, Sachchithananthan, Mythily, Campbell, Ian, De Fazio, Anna, Fox, Stephen, Kirk, Judy, Lindeman, Geoff, Milne, Roger, Southey, Melissa, Spurdle, Amanda, Thorne, Heather, Jager, Agnes, Jakubowska, Anna, John, Esther M, Johnson, Nichola, Jones, Michael E, Jung, Audrey, Kaaks, Rudolf, Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M, Ko, Yon-Dschun, Kosma, Veli-Matti, Koutros, Stella, Kraft, Peter, Kubelka-Sabit, Katerina, Kurian, Allison W, Lacey, James V, Lambrechts, Diether, Larson, Nicole L, Linet, Martha, Ogrodniczak, Alicja, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L, Muranen, Taru A, Murphy, Rachel A, Nevanlinna, Heli, Olson, Janet E, Olsson, Håkan, Park-Simon, Tjoung-Won, Perou, Charles M, Peterlongo, Paolo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Rennert, Gad, Saloustros, Emmanouil, Sandler, Dale P, Sawyer, Elinor J, Schmidt, Marjanka K, Schmutzler, Rita K, Shibli, Rana, Smeets, Ann, Soucy, Penny, Southey, Melissa C, Swerdlow, Anthony J, Tamimi, Rulla M, Taylor, Jack A, Teras, Lauren R, Terry, Mary Beth, Tomlinson, Ian, Troester, Melissa A, Truong, Thérèse, Vachon, Celine M, Wendt, Camilla, Winqvist, Robert, Wolk, Alicja, Yang, Xiaohong R, Zheng, Wei, Ziogas, Argyrios, Simard, Jacques, Dunning, Alison, Pharoah, Paul, Easton, Douglas, Dennis, Joe [0000-0003-4591-1214], Tyrer, Jonathan [0000-0003-3724-4757], Walker, Logan C [0000-0003-0018-3719], Michailidou, Kyriaki [0000-0001-7065-1237], Wang, Jean [0000-0002-9139-0627], Andrulis, Irene L [0000-0002-4226-6435], Arndt, Volker [0000-0001-9320-8684], Aronson, Kristan J [0000-0002-7865-7243], Behrens, Sabine [0000-0002-9714-104X], Kristensen, Vessela N [0000-0001-5012-7438], Dörk, Thilo [0000-0002-9458-0282], Dossus, Laure [0000-0003-2716-5748], Figueroa, Jonine [0000-0002-5100-623X], Fritschi, Lin [0000-0002-7692-3560], Giles, Graham G [0000-0003-4946-9099], Hollestelle, Antoinette [0000-0003-1166-1966], Jakubowska, Anna [0000-0002-5650-0501], Johnson, Nichola [0000-0002-8230-5662], Jones, Michael E [0000-0001-7479-3451], Keeman, Renske [0000-0002-5452-9933], Larson, Nicole L [0000-0002-2129-6934], Milne, Roger L [0000-0001-5764-7268], Nevanlinna, Heli [0000-0002-0916-2976], Olson, Janet E [0000-0003-4944-7789], Peterlongo, Paolo [0000-0001-6951-6855], Plaseska-Karanfilska, Dijana [0000-0001-8877-2416], Pylkäs, Katri [0000-0002-2449-0521], Rennert, Gad [0000-0002-8512-068X], Tomlinson, Ian [0000-0003-3037-1470], Truong, Thérèse [0000-0002-2943-6786], Vachon, Celine M [0000-0002-1962-9322], Wolk, Alicja [0000-0001-7387-6845], Ziogas, Argyrios [0000-0003-4529-3727], Simard, Jacques [0000-0001-6906-3390], Dunning, Alison [0000-0001-6651-7166], Pharoah, Paul [0000-0001-8494-732X], Easton, Douglas [0000-0003-2444-3247], Apollo - University of Cambridge Repository, Wilson, Leila [0000-0003-1214-8080], Clinical Genetics, Medical Oncology, HUS Gynecology and Obstetrics, Department of Obstetrics and Gynecology, and Clinicum
Subjects: endocrine system diseases, 45/43, Medicine (miscellaneous), Genome-wide association studies, Basic medicine, Breast cancer, Other medical sciences, Runx2, Risk Factors, Biology (General), skin and connective tissue diseases, 0303 health sciences, 030305 genetics & heredity, article, 3. Good health, Female, General Agricultural and Biological Sciences, Medical Genetics, Mutations, DNA Copy Number Variations, Locus, QH301-705.5, kConFab/AOCS Investigators, ABCTB Investigators, 631/208/205/2138, Breast Neoplasms, Breast Neoplasms/genetics, General Biochemistry, Genetics and Molecular Biology, NBCS Collaborators, Association, Deletion, 03 medical and health sciences, SDG 3 - Good Health and Well-being, mental disorders, Humans, 030304 developmental biology, Medicinsk genetik, Cancer och onkologi, Genome, Human, Health sciences, 631/67/1347, CTS Consortium, Germ Cells, Genes, Clinical medicine, Cancer and Oncology, Case-Control Studies, 3111 Biomedicine, Structural variation, Brca1, Genome-Wide Association Study
Abstract: Germline copy number variants (CNVs) are pervasive in the human genome but potential disease associations with rare CNVs have not been comprehensively assessed in large datasets. We analysed rare CNVs in genes and non-coding regions for 86,788 breast cancer cases and 76,122 controls of European ancestry with genome-wide array data. Gene burden tests detected the strongest association for deletions in BRCA1 (P = 3.7E−18). Nine other genes were associated with a p-value, Dennis et al. investigate potential breast cancer associations with rare germline copy number variants (CNVs) by conducting a genome-wide analysis in a large breast cancer case-control dataset. The authors detected associations with exonic deletions in established breast cancer susceptibility genes and suggestive associations for a number of non-coding CNVs.
Published: 2021

17. Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

Author: Georgeson, Peter, primary, Harrison, Tabitha A., additional, Pope, Bernard J., additional, Zaidi, Syed H., additional, Qu, Conghui, additional, Steinfelder, Robert S., additional, Lin, Yi, additional, Joo, Jihoon E., additional, Mahmood, Khalid, additional, Clendenning, Mark, additional, Walker, Romy, additional, Amitay, Efrat L., additional, Berndt, Sonja I., additional, Brenner, Hermann, additional, Campbell, Peter T., additional, Cao, Yin, additional, Chan, Andrew T., additional, Chang-Claude, Jenny, additional, Doheny, Kimberly F., additional, Drew, David A., additional, Figueiredo, Jane C., additional, French, Amy J., additional, Gallinger, Steven, additional, Giannakis, Marios, additional, Giles, Graham G., additional, Gsur, Andrea, additional, Gunter, Marc J., additional, Hoffmeister, Michael, additional, Hsu, Li, additional, Huang, Wen-Yi, additional, Limburg, Paul, additional, Manson, JoAnn E., additional, Moreno, Victor, additional, Nassir, Rami, additional, Nowak, Jonathan A., additional, Obón-Santacana, Mireia, additional, Ogino, Shuji, additional, Phipps, Amanda I., additional, Potter, John D., additional, Schoen, Robert E., additional, Sun, Wei, additional, Toland, Amanda E., additional, Trinh, Quang M., additional, Ugai, Tomotaka, additional, Macrae, Finlay A., additional, Rosty, Christophe, additional, Hudson, Thomas J., additional, Jenkins, Mark A., additional, Thibodeau, Stephen N., additional, Winship, Ingrid M., additional, Peters, Ulrike, additional, and Buchanan, Daniel D., additional
Published: 2022
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18. Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci

Author: Chen, Hongjie, Fan, Shaoqi, Stone, Jennifer, Thompson, Deborah J, Douglas, Julie, Li, Shuai, Scott, Christopher, Bolla, Manjeet K, Wang, Qin, Dennis, Joseph, Michailidou, Kyriaki, Li, Christopher, Peters, Ulrike, Hopper, John L, Southey, Melissa C, Nguyen-Dumont, Tu, Nguyen, Tuong L, Fasching, Peter A, Behrens, Annika, Cadby, Gemma, Murphy, Rachel A, Aronson, Kristan, Howell, Anthony, Astley, Susan, Couch, Fergus, Olson, Janet, Milne, Roger L, Giles, Graham G, Haiman, Christopher A, Maskarinec, Gertraud, Winham, Stacey, John, Esther M, Kurian, Allison, Eliassen, Heather, Andrulis, Irene, Evans, D Gareth, Newman, William G, Hall, Per, Czene, Kamila, Swerdlow, Anthony, Jones, Michael, Pollan, Marina, Fernandez-Navarro, Pablo, McConnell, Daniel S, Kristensen, Vessela N, NBCS Investigators, Rothstein, Joseph H, Wang, Pei, Habel, Laurel A, Sieh, Weiva, Dunning, Alison M, Pharoah, Paul, Easton, Douglas F, Gierach, Gretchen L, Tamimi, Rulla M, Vachon, Celine M, Lindström, Sara, Unión Europea. Comisión Europea. H2020, Canadian Institutes of Health Research, Quebec Breast Cancer Foundation, Government of Quebec (Canadá), National Institutes of Health (Estados Unidos), Unión Europea. Comisión Europea. 7 Programa Marco, Cancer Research UK (Reino Unido), Susan G. Komen Breast Cancer Foundation, Ovarian Cancer Research Foundation (Astrualia), Australian Breast Cancer Family Study, NIH - National Cancer Institute (NCI) (Estados Unidos), National Health and Medical Research Council (Australia), New South Wales Cancer Council (Reino Unido), Victorian Health Promotion Foundation, Victorian Cancer Agency, National Breast Cancer Foundation (Australia), Cancer Australia, Universitätsklinikum Erlangen (Alemania), Cancer Council Western Australia (Australia), Consorcio Gallego de Cáncer de Mama (BREOGAN), Instituto de Salud Carlos III, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Galicia Sur Biomedical Foundation, Xunta de Galicia (España), Ministerio de Sanidad, Servicios Sociales e Igualdad (España), Ministerio de Economía y Competitividad (España), Canadian Cancer Society, NIHR - Manchester Biomedical Research Center, Cancer Council Queensland (Australia), Cancer Council New South Wales (Australia), Cancer Council Victoria (Australia), Cancer Council Tasmania (Australia), Cancer Council South (Australia), United States Army Medical Research and Development Command, NIH - NCI-Specialized Programs of Research Excellence (SPORE) in Breast Cancer (Estados Unidos), The Research Council of Norway (Noruega), Southern and Eastern Norway Regional Health Authority (Noruega), Norwegian Cancer Society, Agency for Science, Technology and Research (Singapur), Institute of Cancer Research (Reino Unido), NIHR - Biomedical Research Centre (Reino Unido), Dennis, Joseph [0000-0003-4591-1214], Pharoah, Paul [0000-0001-8494-732X], Lindström, Sara [0000-0002-7137-7281], and Apollo - University of Cambridge Repository
Subjects: Genome-wide association study (GWAS), Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, Breast Neoplasms, Polymorphism, Single Nucleotide, Breast cancer, Phenotype, Humans, Female, Genetic Predisposition to Disease, ddc:610, Transcriptome, Mammographic density, Research Article, Transcriptome-wide association study (TWAS), Breast Density, Genome-Wide Association Study
Abstract: Background: Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA), are associated with breast cancer risk. Twin studies suggest that MD phenotypes are highly heritable. However, only a small proportion of their variance is explained by identified genetic variants. Methods: We conducted a genome-wide association study, as well as a transcriptome-wide association study (TWAS), of age- and BMI-adjusted DA, NDA, and PMD in up to 27,900 European-ancestry women from the MODE/BCAC consortia. Results: We identified 28 genome-wide significant loci for MD phenotypes, including nine novel signals (5q11.2, 5q14.1, 5q31.1, 5q33.3, 5q35.1, 7p11.2, 8q24.13, 12p11.2, 16q12.2). Further, 45% of all known breast cancer SNPs were associated with at least one MD phenotype at p
Published: 2022
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19. An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk

Author: Wu, Lang, Yang, Yaohua, Guo, Xingyi, Shu, Xiao Ou, Cai, Qiuyin, Shu, Xiang, Li, Bingshan, Tao, Ran, Wu, Chong, Nikas, Jason B., Sun, Yanfa, Zhu, Jingjing, Roobol, Monique J., Giles, Graham G., Brenner, Hermann, John, Esther M., Clements, Judith, Grindedal, Eli Marie, Park, Jong Y., Stanford, Janet L., Kote-Jarai, Zsofia, Haiman, Christopher A., Eeles, Rosalind A., Zheng, Wei, Long, Jirong, Henderson, Brian E., Schumacher, Fredrick R., Easton, Douglas, Benlloch, Sara, Olama, Ali Amin Al, Muir, Kenneth, Berndt, Sonja I., Conti, David V., Wiklund, Fredrik, Chanock, Stephen, Gapstur, Susan M., Stevens, Victoria L., Tangen, Catherine M., Batra, Jyotsna, Gronberg, Henrik, Pashayan, Nora, Schleutker, Johanna, Albanes, Demetrius, Weinstein, Stephanie, Wolk, Alicja, Nordestgaard, Børge G., Li, Bingshan [0000-0003-2129-168X], Wu, Chong [0000-0002-8400-1785], Nikas, Jason B [0000-0001-9703-0422], Roobol, Monique J [0000-0001-6967-1708], Giles, Graham G [0000-0003-4946-9099], Park, Jong Y [0000-0002-6384-6447], Eeles, Rosalind A [0000-0002-3698-6241], Zheng, Wei [0000-0003-1226-070X], Apollo - University of Cambridge Repository, Hunter, DJ, consortium, PRACTICAL, Consortium, CRUK, Consortium, BPC3, Consortium, CAPS, Consortium, PEGASUS, and Urology
Subjects: 0301 basic medicine, Male, General Physics and Astronomy, 02 engineering and technology, VARIANTS, urologic and male genital diseases, DISEASE, CRUK Consortium, Prostate cancer, BPC3 Consortium, Risk Factors, Epidemiology of cancer, GWAS, lcsh:Science, Cancer genetics, GENE-EXPRESSION, Genetics, Multidisciplinary, Methylation, 021001 nanoscience & nanotechnology, STATISTICS, Multidisciplinary Sciences, CpG site, DNA methylation, Science & Technology - Other Topics, 0210 nano-technology, SUSCEPTIBILITY LOCI, Science, Biology, Article, General Biochemistry, Genetics and Molecular Biology, PRACTICAL consortium, 03 medical and health sciences, Cancer epidemiology, SDG 3 - Good Health and Well-being, REVEALS, Genetic model, medicine, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, Gene, Genetic Association Studies, Genetic association, Science & Technology, Models, Genetic, MORTALITY, Prostatic Neoplasms, General Chemistry, DNA Methylation, medicine.disease, CAPS Consortium, 030104 developmental biology, TISSUE, ANTIGEN LEVEL, Case-Control Studies, lcsh:Q, CpG Islands, PEGASUS Consortium
Abstract: It remains elusive whether some of the associations identified in genome-wide association studies of prostate cancer (PrCa) may be due to regulatory effects of genetic variants on CpG sites, which may further influence expression of PrCa target genes. To search for CpG sites associated with PrCa risk, here we establish genetic models to predict methylation (N = 1,595) and conduct association analyses with PrCa risk (79,194 cases and 61,112 controls). We identify 759 CpG sites showing an association, including 15 located at novel loci. Among those 759 CpG sites, methylation of 42 is associated with expression of 28 adjacent genes. Among 22 genes, 18 show an association with PrCa risk. Overall, 25 CpG sites show consistent association directions for the methylation-gene expression-PrCa pathway. We identify DNA methylation biomarkers associated with PrCa, and our findings suggest that specific CpG sites may influence PrCa via regulating expression of candidate PrCa target genes., Genome wide association studies have identified multiple loci associated with risk of developing prostate cancer but the functional significance of many of these are unknown. Here, after generating models to predict methylation, the authors identify CpG methylation sites associated with prostate cancer.
Published: 2021
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20. Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

Author: Milne, Roger L, Gaudet, Mia M, Spurdle, Amanda B, Fasching, Peter A, Couch, Fergus J, Benítez, Javier, Arias Pérez, José Ignacio, Zamora, M Pilar, Malats, Núria, dos Santos Silva, Isabel, Gibson, Lorna J, Fletcher, Olivia, Johnson, Nichola, Anton-Culver, Hoda, Ziogas, Argyrios, Figueroa, Jonine, Brinton, Louise, Sherman, Mark E, Lissowska, Jolanta, Hopper, John L, Dite, Gillian S, Apicella, Carmel, Southey, Melissa C, Sigurdson, Alice J, Linet, Martha S, Schonfeld, Sara J, Freedman, D Michal, Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Auvinen, Päivi, Andrulis, Irene L, Glendon, Gord, Knight, Julia A, Weerasooriya, Nayana, Cox, Angela, Reed, Malcolm WR, Cross, Simon S, Dunning, Alison M, Ahmed, Shahana, Shah, Mitul, Brauch, Hiltrud, Ko, Yon-Dschun, Brüning, Thomas, Lambrechts, Diether, Reumers, Joke, Smeets, Ann, Wang-Gohrke, Shan, Hall, Per, Czene, Kamila, Liu, Jianjun, Irwanto, Astrid K, Chenevix-Trench, Georgia, Holland, Helene, Giles, Graham G, Baglietto, Laura, Severi, Gianluca, Bojensen, Stig E, Nordestgaard, Børge G, Flyger, Henrik, John, Esther M, West, Dee W, Whittemore, Alice S, Vachon, Celine, Olson, Janet E, Fredericksen, Zachary, Kosel, Matthew, Hein, Rebecca, Vrieling, Alina, Flesch-Janys, Dieter, Heinz, Judith, Beckmann, Matthias W, Heusinger, Katharina, Ekici, Arif B, Haeberle, Lothar, Humphreys, Manjeet K, Morrison, Jonathan, Easton, Doug F, Pharoah, Paul D, García-Closas, Montserrat, Goode, Ellen L, Chang-Claude, Jenny, Milne, Roger L, Gaudet, Mia M, Spurdle, Amanda B, Fasching, Peter A, Couch, Fergus J, Benítez, Javier, Arias Pérez, José Ignacio, Zamora, M Pilar, Malats, Núria, dos Santos Silva, Isabel, Gibson, Lorna J, Fletcher, Olivia, Johnson, Nichola, Anton-Culver, Hoda, Ziogas, Argyrios, Figueroa, Jonine, Brinton, Louise, Sherman, Mark E, Lissowska, Jolanta, Hopper, John L, Dite, Gillian S, Apicella, Carmel, Southey, Melissa C, Sigurdson, Alice J, Linet, Martha S, Schonfeld, Sara J, Freedman, D Michal, Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Auvinen, Päivi, Andrulis, Irene L, Glendon, Gord, Knight, Julia A, Weerasooriya, Nayana, Cox, Angela, Reed, Malcolm WR, Cross, Simon S, Dunning, Alison M, Ahmed, Shahana, Shah, Mitul, Brauch, Hiltrud, Ko, Yon-Dschun, Brüning, Thomas, Lambrechts, Diether, Reumers, Joke, Smeets, Ann, Wang-Gohrke, Shan, Hall, Per, Czene, Kamila, Liu, Jianjun, Irwanto, Astrid K, Chenevix-Trench, Georgia, Holland, Helene, Giles, Graham G, Baglietto, Laura, Severi, Gianluca, Bojensen, Stig E, Nordestgaard, Børge G, Flyger, Henrik, John, Esther M, West, Dee W, Whittemore, Alice S, Vachon, Celine, Olson, Janet E, Fredericksen, Zachary, Kosel, Matthew, Hein, Rebecca, Vrieling, Alina, Flesch-Janys, Dieter, Heinz, Judith, Beckmann, Matthias W, Heusinger, Katharina, Ekici, Arif B, Haeberle, Lothar, Humphreys, Manjeet K, Morrison, Jonathan, Easton, Doug F, Pharoah, Paul D, García-Closas, Montserrat, Goode, Ellen L, and Chang-Claude, Jenny
Abstract: Introduction: Several common breast cancer genetic susceptibility variants have recently been identified. We aimed to determine how these variants combine with a subset of other known risk factors to influence breast cancer risk in white women of European ancestry using case-control studies participating in the Breast Cancer Association Consortium.Methods: We evaluated two-way interactions between each of age at menarche, ever having had a live birth, number of live births, age at first birth and body mass index (BMI) and each of 12 single nucleotide polymorphisms (SNPs) (10q26-rs2981582 (FGFR2), 8q24-rs13281615, 11p15-rs3817198 (LSP1), 5q11-rs889312 (MAP3K1), 16q12-rs3803662 (TOX3), 2q35-rs13387042, 5p12-rs10941679 (MRPS30), 17q23-rs6504950 (COX11), 3p24-rs4973768 (SLC4A7), CASP8-rs17468277, TGFB1-rs1982073 and ESR1-rs3020314). Interactions were tested for by fitting logistic regression models including per-allele and linear trend main effects for SNPs and risk factors, respectively, and single-parameter interaction terms for linear departure from independent multiplicative effects.Results: These analyses were applied to data for up to 26,349 invasive breast cancer cases and up to 32,208 controls from 21 case-control studies. No statistical evidence of interaction was observed beyond that expected by chance. Analyses were repeated using data from 11 population-based studies, and results were very similar.Conclusions: The relative risks for breast cancer associated with the common susceptibility variants identified to date do not appear to vary across women with different reproductive histories or body mass index (BMI). The assumption of multiplicative combined effects for these established genetic and other risk factors in risk prediction models appears justified. © 2010 Milne et al.; licensee BioMed Central Ltd.
Published: 2022

21. Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking

Author: Petrovic, Dusan, primary, Bodinier, Barbara, additional, Dagnino, Sonia, additional, Whitaker, Matthew, additional, Karimi, Maryam, additional, Campanella, Gianluca, additional, Haugdahl Nøst, Therese, additional, Polidoro, Silvia, additional, Palli, Domenico, additional, Krogh, Vittorio, additional, Tumino, Rosario, additional, Sacerdote, Carlotta, additional, Panico, Salvatore, additional, Lund, Eiliv, additional, Dugué, Pierre-Antoine, additional, Giles, Graham G., additional, Severi, Gianluca, additional, Southey, Melissa, additional, Vineis, Paolo, additional, Stringhini, Silvia, additional, Bochud, Murielle, additional, Sandanger, Torkjel M., additional, Vermeulen, Roel C. H., additional, Guida, Florence, additional, and Chadeau-Hyam, Marc, additional
Published: 2022
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22. Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Author: Wang, Xiaoliang, primary, Kapoor, Pooja Middha, additional, Auer, Paul L., additional, Dennis, Joe, additional, Dunning, Alison M., additional, Wang, Qin, additional, Lush, Michael, additional, Michailidou, Kyriaki, additional, Bolla, Manjeet K., additional, Aronson, Kristan J., additional, Murphy, Rachel A., additional, Brooks-Wilson, Angela, additional, Lee, Derrick G., additional, Cordina-Duverger, Emilie, additional, Guénel, Pascal, additional, Truong, Thérèse, additional, Mulot, Claire, additional, Teras, Lauren R., additional, Patel, Alpa V., additional, Dossus, Laure, additional, Kaaks, Rudolf, additional, Hoppe, Reiner, additional, Lo, Wing-Yee, additional, Brüning, Thomas, additional, Hamann, Ute, additional, Czene, Kamila, additional, Gabrielson, Marike, additional, Hall, Per, additional, Eriksson, Mikael, additional, Jung, Audrey, additional, Becher, Heiko, additional, Couch, Fergus J., additional, Larson, Nicole L., additional, Olson, Janet E., additional, Ruddy, Kathryn J., additional, Giles, Graham G., additional, MacInnis, Robert J., additional, Southey, Melissa C., additional, Le Marchand, Loic, additional, Wilkens, Lynne R., additional, Haiman, Christopher A., additional, Olsson, Håkan, additional, Augustinsson, Annelie, additional, Krüger, Ute, additional, Wagner, Philippe, additional, Scott, Christopher, additional, Winham, Stacey J., additional, Vachon, Celine M., additional, Perou, Charles M., additional, Olshan, Andrew F., additional, Troester, Melissa A., additional, Hunter, David J., additional, Eliassen, Heather A., additional, Tamimi, Rulla M., additional, Brantley, Kristen, additional, Andrulis, Irene L., additional, Figueroa, Jonine, additional, Chanock, Stephen J., additional, Ahearn, Thomas U., additional, García-Closas, Montserrat, additional, Evans, Gareth D., additional, Newman, William G., additional, van Veen, Elke M., additional, Howell, Anthony, additional, Wolk, Alicja, additional, Håkansson, Niclas, additional, Anton-Culver, Hoda, additional, Ziogas, Argyrios, additional, Jones, Michael E., additional, Orr, Nick, additional, Schoemaker, Minouk J., additional, Swerdlow, Anthony J., additional, Kitahara, Cari M., additional, Linet, Martha, additional, Prentice, Ross L., additional, Easton, Douglas F., additional, Milne, Roger L., additional, Kraft, Peter, additional, Chang-Claude, Jenny, additional, and Lindström, Sara, additional
Published: 2022
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23. Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM

Author: Renault, Anne-Laure, primary, Dowty, James G., additional, Steen, Jason A., additional, Li, Shuai, additional, Winship, Ingrid M., additional, Giles, Graham G., additional, Hopper, John L., additional, Southey, Melissa C., additional, and Nguyen-Dumont, Tú, additional
Published: 2022
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24. Population-based estimates of breast cancer risk for carriers of pathogenic variants identified by gene-panel testing

Author: Southey, Melissa C., Dowty, James G., Riaz, Moeen, Steen, Jason A., Renault, Anne-Laure, Tucker, Katherine, Kirk, Judy, James, Paul, Winship, Ingrid, Pachter, Nicholas, Poplawski, Nicola, Grist, Scott, Park, Daniel J., Pope, Bernard J., Mahmood, Khalid, Hammet, Fleur, Mahmoodi, Maryam, Tsimiklis, Helen, Theys, Derrick, Rewse, Amanda, Willis, Amanda, Morrow, April, Speechly, Catherine, Harris, Rebecca, Sebra, Robert, Schadt, Eric, Lacaze, Paul, McNeil, John J., Giles, Graham G., Milne, Roger L., Hopper, John L., and Nguyen-Dumont, Tú
Subjects: Breast cancer, Genetic testing, Oncology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Pharmacology (medical), Radiology, Nuclear Medicine and imaging, RC254-282, Article
Abstract: Population-based estimates of breast cancer risk for carriers of pathogenic variants identified by gene-panel testing are urgently required. Most prior research has been based on women selected for high-risk features and more data is needed to make inference about breast cancer risk for women unselected for family history, an important consideration of population screening. We tested 1464 women diagnosed with breast cancer and 862 age-matched controls participating in the Australian Breast Cancer Family Study (ABCFS), and 6549 healthy, older Australian women enroled in the ASPirin in Reducing Events in the Elderly (ASPREE) study for rare germline variants using a 24-gene-panel. Odds ratios (ORs) were estimated using unconditional logistic regression adjusted for age and other potential confounders. We identified pathogenic variants in 11.1% of the ABCFS cases, 3.7% of the ABCFS controls and 2.2% of the ASPREE (control) participants. The estimated breast cancer OR [95% confidence interval] was 5.3 [2.1–16.2] for BRCA1, 4.0 [1.9–9.1] for BRCA2, 3.4 [1.4–8.4] for ATM and 4.3 [1.0–17.0] for PALB2. Our findings provide a population-based perspective to gene-panel testing for breast cancer predisposition and opportunities to improve predictors for identifying women who carry pathogenic variants in breast cancer predisposition genes.
Published: 2021

25. Physical activity and glioma: a case–control study with follow-up for survival

Author: Basiri, Zohreh, primary, Yang, Yi, additional, Bruinsma, Fiona J., additional, Nowak, Anna K., additional, McDonald, Kerrie L., additional, Drummond, Katharine J., additional, Rosenthal, Mark A., additional, Koh, Eng-Siew, additional, Harrup, Rosemary, additional, Hovey, Elizabeth, additional, Joseph, David, additional, Benke, Geza, additional, Leonard, Robyn, additional, MacInnis, Robert J., additional, Milne, Roger L., additional, Giles, Graham G., additional, Vajdic, Claire M., additional, and Lynch, Brigid M., additional
Published: 2022
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26. Association of allergic diseases and epilepsy with risk of glioma, meningioma and acoustic neuroma: results from the INTERPHONE international case–control study

Author: Schlehofer, Brigitte, primary, Blettner, Maria, additional, Moissonnier, Monika, additional, Deltour, Isabelle, additional, Giles, Graham G., additional, Armstrong, Bruce, additional, Siemiatycki, Jack, additional, Parent, Marie-Elise, additional, Krewski, Daniel, additional, Johansen, Christoffer, additional, Auvinen, Anssi, additional, Lahkola, Anna, additional, Hours, Martine, additional, Berg-Beckhoff, Gabriele, additional, Sadetzki, Siegal, additional, Lagorio, Susanna, additional, Takebayashi, Toru, additional, Yamaguchi, Naohito, additional, Woodward, Alistair, additional, Cook, Angus, additional, Tynes, Tore, additional, Klaboe, Lars, additional, Feychting, Maria, additional, Feltbower, Richard, additional, Swerdlow, Anthony, additional, Schoemaker, Minouk, additional, Cardis, Elisabeth, additional, and Schüz, Joachim, additional
Published: 2022
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27. Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival

Author: Labadie, Julia D., primary, Savas, Sevtap, additional, Harrison, Tabitha A., additional, Banbury, Barb, additional, Huang, Yuhan, additional, Buchanan, Daniel D., additional, Campbell, Peter T., additional, Gallinger, Steven J., additional, Giles, Graham G., additional, Gunter, Marc J., additional, Hoffmeister, Michael, additional, Hsu, Li, additional, Jenkins, Mark A., additional, Lin, Yi, additional, Ogino, Shuji, additional, Phipps, Amanda I., additional, Slattery, Martha L., additional, Steinfelder, Robert S., additional, Sun, Wei, additional, Van Guelpen, Bethany, additional, Hua, Xinwei, additional, Figuieredo, Jane C., additional, Pai, Rish K., additional, Nassir, Rami, additional, Qi, Lihong, additional, Chan, Andrew T., additional, Peters, Ulrike, additional, and Newcomb, Polly A., additional
Published: 2022
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28. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Author: Zhang, Haoyu, Ahearn, Thomas U, Lecarpentier, Julie, Barnes, Daniel, Beesley, Jonathan, Qi, Guanghao, Jiang, Xia, O'Mara, Tracy A, Zhao, Ni, Bolla, Manjeet K, Dunning, Alison M, Dennis, Joe, Wang, Qin, Ful, Zumuruda Abu, Aittomäki, Kristiina, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Aronson, Kristan J, Arun, Banu K, Auer, Paul L, Azzollini, Jacopo, Barrowdale, Daniel, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bialkowska, Katarzyna, Blanco, Ana, Blomqvist, Carl, Bogdanova, Natalia V, Bojesen, Stig E, Bonanni, Bernardo, Bondavalli, Davide, Borg, Ake, Brauch, Hiltrud, Brenner, Hermann, Briceno, Ignacio, Broeks, Annegien, Brucker, Sara Y, Brüning, Thomas, Burwinkel, Barbara, Buys, Saundra S, Byers, Helen, Caldés, Trinidad, Caligo, Maria A, Calvello, Mariarosaria, Campa, Daniele, Castelao, Jose E, Chang-Claude, Jenny, Chanock, Stephen J, Christiaens, Melissa, Christiansen, Hans, Chung, Wendy K, Claes, Kathleen BM, Clarke, Christine L, Cornelissen, Sten, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, Peter, Diez, Orland, Domchek, Susan M, Dörk, Thilo, Dwek, Miriam, Eccles, Diana M, Ekici, Arif B, Evans, D Gareth, Fasching, Peter A, Figueroa, Jonine, Foretova, Lenka, Fostira, Florentia, Friedman, Eitan, Frost, Debra, Gago-Dominguez, Manuela, Gapstur, Susan M, Garber, Judy, García-Sáenz, José A, Gaudet, Mia M, Gayther, Simon A, Giles, Graham G, Godwin, Andrew K, Goldberg, Mark S, Goldgar, David E, González-Neira, Anna, Greene, Mark H, Gronwald, Jacek, Guénel, Pascal, Häberle, Lothar, Hahnen, Eric, Haiman, Christopher A, Hake, Christopher R, Hall, Per, Hamann, Ute, Harkness, Elaine F, Heemskerk-Gerritsen, Bernadette AM, Hillemanns, Peter, Hogervorst, Frans BL, Holleczek, Bernd, Hollestelle, Antoinette, Hooning, Maartje J, Hoover, Robert N, Hopper, John L, Howell, Anthony, Huebner, Hanna, Hulick, Peter J, Imyanitov, Evgeny N, kConFab Investigators, ABCTB Investigators, Isaacs, Claudine, Izatt, Louise, Jager, Agnes, Jakimovska, Milena, Jakubowska, Anna, James, Paul, Janavicius, Ramunas, Janni, Wolfgang, John, Esther M, Jones, Michael E, Jung, Audrey, Kaaks, Rudolf, Kapoor, Pooja Middha, Karlan, Beth Y, Keeman, Renske, Khan, Sofia, Khusnutdinova, Elza, Kitahara, Cari M, Ko, Yon-Dschun, Konstantopoulou, Irene, Koppert, Linetta B, Koutros, Stella, Kristensen, Vessela N, Laenkholm, Anne-Vibeke, Lambrechts, Diether, Larsson, Susanna C, Laurent-Puig, Pierre, Lazaro, Conxi, Lazarova, Emilija, Lejbkowicz, Flavio, Leslie, Goska, Lesueur, Fabienne, Lindblom, Annika, Lissowska, Jolanta, Lo, Wing-Yee, Loud, Jennifer T, Lubinski, Jan, Lukomska, Alicja, MacInnis, Robert J, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Martinez, Maria Elena, Matricardi, Laura, McGuffog, Lesley, McLean, Catriona, Mebirouk, Noura, Meindl, Alfons, Menon, Usha, Miller, Austin, Mingazheva, Elvira, Montagna, Marco, Mulligan, Anna Marie, Mulot, Claire, Muranen, Taru A, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, Neven, Patrick, Newman, William G, Nielsen, Finn C, Nikitina-Zake, Liene, Nodora, Jesse, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Olsson, Håkan, Orr, Nick, Papi, Laura, Papp, Janos, Park-Simon, Tjoung-Won, Parsons, Michael T, Peissel, Bernard, Peixoto, Ana, Peshkin, Beth, Peterlongo, Paolo, Peto, Julian, Phillips, Kelly-Anne, Piedmonte, Marion, Plaseska-Karanfilska, Dijana, Prajzendanc, Karolina, Prentice, Ross, Prokofyeva, Darya, Rack, Brigitte, Radice, Paolo, Ramus, Susan J, Rantala, Johanna, Rashid, Muhammad U, Rennert, Gad, Rennert, Hedy S, Risch, Harvey A, Romero, Atocha, Rookus, Matti A, Rübner, Matthias, Rüdiger, Thomas, Saloustros, Emmanouil, Sampson, Sarah, Sandler, Dale P, Sawyer, Elinor J, Scheuner, Maren T, Schmutzler, Rita K, Schneeweiss, Andreas, Schoemaker, Minouk J, Schöttker, Ben, Schürmann, Peter, Senter, Leigha, Sharma, Priyanka, Sherman, Mark E, Shu, Xiao-Ou, Singer, Christian F, Smichkoska, Snezhana, Soucy, Penny, Southey, Melissa C, Spinelli, John J, Stone, Jennifer, Stoppa-Lyonnet, Dominique, EMBRACE Study, GEMO Study Collaborators, Swerdlow, Anthony J, Szabo, Csilla I, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Teixeira, Manuel R, Terry, MaryBeth, Thomassen, Mads, Thull, Darcy L, Tischkowitz, Marc, Toland, Amanda E, Tollenaar, Rob AEM, Tomlinson, Ian, Torres, Diana, Troester, Melissa A, Truong, Thérèse, Tung, Nadine, Untch, Michael, Vachon, Celine M, van den Ouweland, Ans MW, van der Kolk, Lizet E, van Veen, Elke M, vanRensburg, Elizabeth J, Vega, Ana, Wappenschmidt, Barbara, Weinberg, Clarice R, Weitzel, Jeffrey N, Wildiers, Hans, Winqvist, Robert, Wolk, Alicja, Yang, Xiaohong R, Yannoukakos, Drakoulis, Zheng, Wei, Zorn, Kristin K, Milne, Roger L, Kraft, Peter, Simard, Jacques, Pharoah, Paul DP, Michailidou, Kyriaki, Antoniou, Antonis C, Schmidt, Marjanka K, Chenevix-Trench, Georgia, Easton, Douglas F, Chatterjee, Nilanjan, García-Closas, Montserrat, Barnes, Daniel [0000-0002-3781-7570], O'Mara, Tracy A [0000-0002-5436-3232], Dunning, Alison M [0000-0001-6651-7166], Dennis, Joe [0000-0003-4591-1214], Andrulis, Irene L [0000-0002-4226-6435], Arndt, Volker [0000-0001-9320-8684], Azzollini, Jacopo [0000-0002-9364-9778], Bojesen, Stig E [0000-0002-4061-4133], Bonanni, Bernardo [0000-0003-3589-2128], Brauch, Hiltrud [0000-0001-7531-2736], Caldés, Trinidad [0000-0002-1038-5392], Calvello, Mariarosaria [0000-0003-2113-8503], Chanock, Stephen J [0000-0002-2324-3393], Claes, Kathleen BM [0000-0003-0841-7372], Devilee, Peter [0000-0002-8023-2009], Dörk, Thilo [0000-0002-9458-0282], Dwek, Miriam [0000-0001-7184-2932], Ekici, Arif B [0000-0001-6099-7066], Fasching, Peter A [0000-0003-4885-8471], García-Sáenz, José A [0000-0001-6880-0301], Gayther, Simon A [0000-0001-7937-5443], Giles, Graham G [0000-0003-4946-9099], Greene, Mark H [0000-0003-1852-9239], Guénel, Pascal [0000-0002-8359-518X], Harkness, Elaine F [0000-0001-6625-7739], Heemskerk-Gerritsen, Bernadette AM [0000-0002-9724-6693], Hollestelle, Antoinette [0000-0003-1166-1966], Huebner, Hanna [0000-0001-6889-1493], Hulick, Peter J [0000-0001-8397-4078], Jakimovska, Milena [0000-0002-1506-0669], Jakubowska, Anna [0000-0002-5650-0501], James, Paul [0000-0002-4361-4657], Jones, Michael E [0000-0001-7479-3451], Kapoor, Pooja Middha [0000-0001-5503-8215], Keeman, Renske [0000-0002-5452-9933], Konstantopoulou, Irene [0000-0002-0470-0309], Larsson, Susanna C [0000-0003-0118-0341], Laurent-Puig, Pierre [0000-0001-8475-5459], Leslie, Goska [0000-0001-5756-6222], Lesueur, Fabienne [0000-0001-7404-4549], Lissowska, Jolanta [0000-0003-2695-5799], Matricardi, Laura [0000-0002-0241-1810], McLean, Catriona [0000-0002-0302-5727], Menon, Usha [0000-0003-3708-1732], Miller, Austin [0000-0001-9739-8462], Muranen, Taru A [0000-0002-5895-1808], Nathanson, Katherine L [0000-0002-6740-0901], Nevanlinna, Heli [0000-0002-0916-2976], Newman, William G [0000-0002-6382-4678], Olopade, Olufunmilayo I [0000-0002-9936-1599], Orr, Nick [0000-0003-2866-942X], Parsons, Michael T [0000-0003-3242-8477], Peshkin, Beth [0000-0002-2997-4701], Peterlongo, Paolo [0000-0001-6951-6855], Peto, Julian [0000-0002-1685-8912], Plaseska-Karanfilska, Dijana [0000-0001-8877-2416], Radice, Paolo [0000-0001-6298-4111], Rennert, Gad [0000-0002-8512-068X], Romero, Atocha [0000-0002-1634-7397], Saloustros, Emmanouil [0000-0002-0485-0120], Stone, Jennifer [0000-0001-5077-0124], Teixeira, Manuel R [0000-0002-4896-5982], Toland, Amanda E [0000-0002-0271-1792], Tomlinson, Ian [0000-0003-3037-1470], van Veen, Elke M [0000-0001-8618-2332], vanRensburg, Elizabeth J [0000-0003-2077-230X], Weitzel, Jeffrey N [0000-0001-6714-092X], Winqvist, Robert [0000-0003-0932-9104], Wolk, Alicja [0000-0001-7387-6845], Yannoukakos, Drakoulis [0000-0001-7509-3510], Zheng, Wei [0000-0003-1226-070X], Milne, Roger L [0000-0001-5764-7268], Kraft, Peter [0000-0002-4472-8103], Simard, Jacques [0000-0001-6906-3390], Pharoah, Paul DP [0000-0001-8494-732X], Michailidou, Kyriaki [0000-0001-7065-1237], Schmidt, Marjanka K [0000-0002-2228-429X], Easton, Douglas F [0000-0003-2444-3247], Chatterjee, Nilanjan [0000-0002-9060-008X], García-Closas, Montserrat [0000-0003-1033-2650], and Apollo - University of Cambridge Repository
Subjects: BRCA1 Protein, Case-Control Studies, Mutation, Humans, Breast Neoplasms, Female, Genetic Predisposition to Disease, Triple Negative Breast Neoplasms, Linkage Disequilibrium, Genome-Wide Association Study
Abstract: Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype1-3. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls, plus 18,908 BRCA1 mutation carriers (9,414 with breast cancer) of European ancestry, using both standard and novel methodologies that account for underlying tumor heterogeneity by estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 status and tumor grade. We identified 32 novel susceptibility loci (P
Published: 2020

29. Mendelian randomisation study of smoking exposure in relation to breast cancer risk

Author: Park, Hanla A, Neumeyer, Sonja, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Aronson, Kristan J, Augustinsson, Annelie, Baten, Adinda, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bogdanova, Natalia V, Bojesen, Stig E, Brauch, Hiltrud, Brenner, Hermann, Brucker, Sara Y, Burwinkel, Barbara, Campa, Daniele, Canzian, Federico, Castelao, Jose E, Chanock, Stephen J, Chenevix-Trench, Georgia, Clarke, Christine L, NBCS Collaborators, Conroy, Don M, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, Peter, Dörk, Thilo, Dos-Santos-Silva, Isabel, Dwek, Miriam, Eccles, Diana M, Eliassen, A Heather, Engel, Christoph, Eriksson, Mikael, Evans, D Gareth, Fasching, Peter A, Flyger, Henrik, Fritschi, Lin, García-Closas, Montserrat, García-Sáenz, José A, Gaudet, Mia M, Giles, Graham G, Glendon, Gord, Goldberg, Mark S, Goldgar, David E, González-Neira, Anna, Grip, Mervi, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Han, Sileny, Harkness, Elaine F, Hart, Steven N, He, Wei, Heemskerk-Gerritsen, Bernadette AM, Hopper, John L, Hunter, David J, ABCTB Investigators, kConFab Investigators, Jager, Agnes, Jakubowska, Anna, John, Esther M, Jung, Audrey, Kaaks, Rudolf, Kapoor, Pooja Middha, Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M, Koppert, Linetta B, Koutros, Stella, Kristensen, Vessela N, Kurian, Allison W, Lacey, James, Lambrechts, Diether, Le Marchand, Loic, Lo, Wing-Yee, Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Martinez, Maria Elena, Mavroudis, Dimitrios, Meindl, Alfons, Menon, Usha, Milne, Roger L, Muranen, Taru A, Nevanlinna, Heli, Newman, William G, Nordestgaard, Børge G, Offit, Kenneth, Olshan, Andrew F, Olsson, Håkan, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Peto, Julian, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Radice, Paolo, Rennert, Gad, Rennert, Hedy S, Romero, Atocha, Saloustros, Emmanouil, Sawyer, Elinor J, Schmidt, Marjanka K, Schmutzler, Rita K, Schoemaker, Minouk J, Schwentner, Lukas, Scott, Christopher, Shah, Mitul, Shu, Xiao-Ou, Simard, Jacques, Smeets, Ann, Southey, Melissa C, Spinelli, John J, Stevens, Victoria, Swerdlow, Anthony J, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Terry, Mary Beth, Tomlinson, Ian, Troester, Melissa A, Truong, Thérèse, Vachon, Celine M, van Veen, Elke M, Vijai, Joseph, Wang, Sophia, Wendt, Camilla, Winqvist, Robert, Wolk, Alicja, Ziogas, Argyrios, Dunning, Alison M, Pharoah, Paul DP, Easton, Douglas F, Zheng, Wei, Kraft, Peter, and Chang-Claude, Jenny
Abstract: BACKGROUND: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies, it is still equivocal whether smoking is causally related to breast cancer risk. METHODS: We applied Mendelian randomisation (MR) to evaluate a potential causal effect of cigarette smoking on breast cancer risk. Both individual-level data as well as summary statistics for 164 single-nucleotide polymorphisms (SNPs) reported in genome-wide association studies of lifetime smoking index (LSI) or cigarette per day (CPD) were used to obtain MR effect estimates. Data from 108,420 invasive breast cancer cases and 87,681 controls were used for the LSI analysis and for the CPD analysis conducted among ever-smokers from 26,147 cancer cases and 26,072 controls. Sensitivity analyses were conducted to address pleiotropy. RESULTS: Genetically predicted LSI was associated with increased breast cancer risk (OR 1.18 per SD, 95% CI: 1.07-1.30, P = 0.11 × 10-2), but there was no evidence of association for genetically predicted CPD (OR 1.02, 95% CI: 0.78-1.19, P = 0.85). The sensitivity analyses yielded similar results and showed no strong evidence of pleiotropic effect. CONCLUSION: Our MR study provides supportive evidence for a potential causal association with breast cancer risk for lifetime smoking exposure but not cigarettes per day among smokers.
Published: 2021

30. Repeatability of methylation measures using a QIAseq targeted methyl panel and comparison with the Illumina HumanMethylation450 assay

Author: Yu, Chenglong, primary, Dugué, Pierre-Antoine, additional, Dowty, James G., additional, Hammet, Fleur, additional, Joo, JiHoon E., additional, Wong, Ee Ming, additional, Hosseinpour, Mahnaz, additional, Giles, Graham G., additional, Hopper, John L., additional, Nguyen-Dumont, Tu, additional, MacInnis, Robert J., additional, and Southey, Melissa C., additional
Published: 2021
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31. Association between circulating 25-hydroxyvitamin D concentrations and hip replacement for osteoarthritis: a prospective cohort study

Author: Hussain, Sultana Monira, primary, Wang, Yuanyuan, additional, Heath, Alicia K., additional, Giles, Graham G., additional, English, Dallas R., additional, Eyles, Darryl W., additional, Williamson, Elizabeth J., additional, Graves, Stephen E., additional, Wluka, Anita E., additional, and Cicuttini, Flavia M., additional
Published: 2021
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32. KLK3 SNP-SNP interactions for prediction of prostate cancer aggressiveness

Author: Lin, Hui-Yi, Huang, Po-Yu, Cheng, Chia-Ho, Tung, Heng-Yuan, Fang, Zhide, Berglund, Anders E, Chen, Ann, French-Kwawu, Jennifer, Harris, Darian, Pow-Sang, Julio, Yamoah, Kosj, Cleveland, John L, Awasthi, Shivanshu, Rounbehler, Robert J, Gerke, Travis, Dhillon, Jasreman, Eeles, Rosalind, Kote-Jarai, Zsofia, Muir, Kenneth, UKGPCS Collaborators, Schleutker, Johanna, Pashayan, Nora, APCB (Australian Prostate Cancer BioResource), Neal, David E, Nielsen, Sune F, Nordestgaard, Børge G, Gronberg, Henrik, Wiklund, Fredrik, Giles, Graham G, Haiman, Christopher A, Travis, Ruth C, Stanford, Janet L, Kibel, Adam S, Cybulski, Cezary, Khaw, Kay-Tee, Maier, Christiane, Thibodeau, Stephen N, Teixeira, Manuel R, Cannon-Albright, Lisa, Brenner, Hermann, Kaneva, Radka, Pandha, Hardev, PRACTICAL Consortium, Srinivasan, Srilakshmi, Clements, Judith, Batra, Jyotsna, Park, Jong Y, and Apollo - University of Cambridge Repository
Subjects: Male, Genotype, Biomarkers, Tumor, Humans, Prostatic Neoplasms, Epistasis, Genetic, Genetic Predisposition to Disease, Kallikreins, Prostate-Specific Antigen, urologic and male genital diseases, Polymorphism, Single Nucleotide
Abstract: Risk classification for prostate cancer (PCa) aggressiveness and underlying mechanisms remain inadequate. Interactions between single nucleotide polymorphisms (SNPs) may provide a solution to fill these gaps. To identify SNP-SNP interactions in the four pathways (the angiogenesis-, mitochondria-, miRNA-, and androgen metabolism-related pathways) associated with PCa aggressiveness, we tested 8587 SNPs for 20,729 cases from the PCa consortium. We identified 3 KLK3 SNPs, and 1083 (P < 3.5 × 10-9) and 3145 (P < 1 × 10-5) SNP-SNP interaction pairs significantly associated with PCa aggressiveness. These SNP pairs associated with PCa aggressiveness were more significant than each of their constituent SNP individual effects. The majority (98.6%) of the 3145 pairs involved KLK3. The 3 most common gene-gene interactions were KLK3-COL4A1:COL4A2, KLK3-CDH13, and KLK3-TGFBR3. Predictions from the SNP interaction-based polygenic risk score based on 24 SNP pairs are promising. The prevalence of PCa aggressiveness was 49.8%, 21.9%, and 7.0% for the PCa cases from our cohort with the top 1%, middle 50%, and bottom 1% risk profiles. Potential biological functions of the identified KLK3 SNP-SNP interactions were supported by gene expression and protein-protein interaction results. Our findings suggest KLK3 SNP interactions may play an important role in PCa aggressiveness.
Published: 2021

33. Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults

Author: Zahed, Hana, primary, Johansson, Mattias, additional, Ueland, Per M., additional, Midttun, Øivind, additional, Milne, Roger L., additional, Giles, Graham G., additional, Manjer, Jonas, additional, Sandsveden, Malte, additional, Langhammer, Arnulf, additional, Sørgjerd, Elin Pettersen, additional, Grankvist, Kjell, additional, Johansson, Mikael, additional, Freedman, Neal D., additional, Huang, Wen-Yi, additional, Chen, Chu, additional, Prentice, Ross, additional, Stevens, Victoria L., additional, Wang, Ying, additional, Le Marchand, Loic, additional, Wilkens, Lynne R., additional, Weinstein, Stephanie J., additional, Albanes, Demetrius, additional, Cai, Qiuyin, additional, Blot, William J., additional, Arslan, Alan A., additional, Zeleniuch-Jacquotte, Anne, additional, Shu, Xiao-Ou, additional, Zheng, Wei, additional, Yuan, Jian-Min, additional, Koh, Woon-Puay, additional, Visvanathan, Kala, additional, Sesso, Howard D., additional, Zhang, Xuehong, additional, Gaziano, J. Michael, additional, Fanidi, Anouar, additional, Muller, David, additional, Brennan, Paul, additional, Guida, Florence, additional, and Robbins, Hilary A., additional
Published: 2021
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34. Correction to: The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability

Author: Russell, Holly, primary, Kedzierska, Katarzyna, additional, Buchanan, Daniel D., additional, Thomas, Rachael, additional, Tham, Emma, additional, Mints, Miriam, additional, Keränen, Anne, additional, Giles, Graham G., additional, Southey, Melissa C., additional, Milne, Roger L., additional, Tomlinson, Ian, additional, Church, David, additional, Spurdle, Amanda B., additional, O’Mara, Tracy A., additional, and Lewis, Annabelle, additional
Published: 2021
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35. Vegetable intake and the risk of bladder cancer in the BLadder Cancer Epidemiology and Nutritional Determinants (BLEND) international study

Author: Yu, Evan Yi-Wen, primary, Wesselius, Anke, additional, Mehrkanoon, Siamak, additional, Goosens, Mieke, additional, Brinkman, Maree, additional, van den Brandt, Piet, additional, Grant, Eric J., additional, White, Emily, additional, Weiderpass, Elisabete, additional, Le Calvez-Kelm, Florence, additional, Gunter, Marc J., additional, Huybrechts, Inge, additional, Riboli, Elio, additional, Tjonneland, Anne, additional, Masala, Giovanna, additional, Giles, Graham G., additional, Milne, Roger L., additional, and Zeegers, Maurice P., additional
Published: 2021
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36. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Author: Conti, David V., primary, Darst, Burcu F., additional, Moss, Lilit C., additional, Saunders, Edward J., additional, Sheng, Xin, additional, Chou, Alisha, additional, Schumacher, Fredrick R., additional, Olama, Ali Amin Al, additional, Benlloch, Sara, additional, Dadaev, Tokhir, additional, Brook, Mark N., additional, Sahimi, Ali, additional, Hoffmann, Thomas J., additional, Takahashi, Atushi, additional, Matsuda, Koichi, additional, Momozawa, Yukihide, additional, Fujita, Masashi, additional, Muir, Kenneth, additional, Lophatananon, Artitaya, additional, Wan, Peggy, additional, Le Marchand, Loic, additional, Wilkens, Lynne R., additional, Stevens, Victoria L., additional, Gapstur, Susan M., additional, Carter, Brian D., additional, Schleutker, Johanna, additional, Tammela, Teuvo L. J., additional, Sipeky, Csilla, additional, Auvinen, Anssi, additional, Giles, Graham G., additional, Southey, Melissa C., additional, MacInnis, Robert J., additional, Cybulski, Cezary, additional, Wokołorczyk, Dominika, additional, Lubiński, Jan, additional, Neal, David E., additional, Donovan, Jenny L., additional, Hamdy, Freddie C., additional, Martin, Richard M., additional, Nordestgaard, Børge G., additional, Nielsen, Sune F., additional, Weischer, Maren, additional, Bojesen, Stig E., additional, Røder, Martin Andreas, additional, Iversen, Peter, additional, Batra, Jyotsna, additional, Chambers, Suzanne, additional, Moya, Leire, additional, Horvath, Lisa, additional, Clements, Judith A., additional, Tilley, Wayne, additional, Risbridger, Gail P., additional, Gronberg, Henrik, additional, Aly, Markus, additional, Szulkin, Robert, additional, Eklund, Martin, additional, Nordström, Tobias, additional, Pashayan, Nora, additional, Dunning, Alison M., additional, Ghoussaini, Maya, additional, Travis, Ruth C., additional, Key, Tim J., additional, Riboli, Elio, additional, Park, Jong Y., additional, Sellers, Thomas A., additional, Lin, Hui-Yi, additional, Albanes, Demetrius, additional, Weinstein, Stephanie J., additional, Mucci, Lorelei A., additional, Giovannucci, Edward, additional, Lindstrom, Sara, additional, Kraft, Peter, additional, Hunter, David J., additional, Penney, Kathryn L., additional, Turman, Constance, additional, Tangen, Catherine M., additional, Goodman, Phyllis J., additional, Thompson, Ian M., additional, Hamilton, Robert J., additional, Fleshner, Neil E., additional, Finelli, Antonio, additional, Parent, Marie-Élise, additional, Stanford, Janet L., additional, Ostrander, Elaine A., additional, Geybels, Milan S., additional, Koutros, Stella, additional, Freeman, Laura E. Beane, additional, Stampfer, Meir, additional, Wolk, Alicja, additional, Håkansson, Niclas, additional, Andriole, Gerald L., additional, Hoover, Robert N., additional, Machiela, Mitchell J., additional, Sørensen, Karina Dalsgaard, additional, Borre, Michael, additional, Blot, William J., additional, Zheng, Wei, additional, Yeboah, Edward D., additional, Mensah, James E., additional, Lu, Yong-Jie, additional, Zhang, Hong-Wei, additional, Feng, Ninghan, additional, Mao, Xueying, additional, Wu, Yudong, additional, Zhao, Shan-Chao, additional, Sun, Zan, additional, Thibodeau, Stephen N., additional, McDonnell, Shannon K., additional, Schaid, Daniel J., additional, West, Catharine M. L., additional, Burnet, Neil, additional, Barnett, Gill, additional, Maier, Christiane, additional, Schnoeller, Thomas, additional, Luedeke, Manuel, additional, Kibel, Adam S., additional, Drake, Bettina F., additional, Cussenot, Olivier, additional, Cancel-Tassin, Géraldine, additional, Menegaux, Florence, additional, Truong, Thérèse, additional, Koudou, Yves Akoli, additional, John, Esther M., additional, Grindedal, Eli Marie, additional, Maehle, Lovise, additional, Khaw, Kay-Tee, additional, Ingles, Sue A., additional, Stern, Mariana C., additional, Vega, Ana, additional, Gómez-Caamaño, Antonio, additional, Fachal, Laura, additional, Rosenstein, Barry S., additional, Kerns, Sarah L., additional, Ostrer, Harry, additional, Teixeira, Manuel R., additional, Paulo, Paula, additional, Brandão, Andreia, additional, Watya, Stephen, additional, Lubwama, Alexander, additional, Bensen, Jeannette T., additional, Fontham, Elizabeth T. H., additional, Mohler, James, additional, Taylor, Jack A., additional, Kogevinas, Manolis, additional, Llorca, Javier, additional, Castaño-Vinyals, Gemma, additional, Cannon-Albright, Lisa, additional, Teerlink, Craig C., additional, Huff, Chad D., additional, Strom, Sara S., additional, Multigner, Luc, additional, Blanchet, Pascal, additional, Brureau, Laurent, additional, Kaneva, Radka, additional, Slavov, Chavdar, additional, Mitev, Vanio, additional, Leach, Robin J., additional, Weaver, Brandi, additional, Brenner, Hermann, additional, Cuk, Katarina, additional, Holleczek, Bernd, additional, Saum, Kai-Uwe, additional, Klein, Eric A., additional, Hsing, Ann W., additional, Kittles, Rick A., additional, Murphy, Adam B., additional, Logothetis, Christopher J., additional, Kim, Jeri, additional, Neuhausen, Susan L., additional, Steele, Linda, additional, Ding, Yuan Chun, additional, Isaacs, William B., additional, Nemesure, Barbara, additional, Hennis, Anselm J. M., additional, Carpten, John, additional, Pandha, Hardev, additional, Michael, Agnieszka, additional, De Ruyck, Kim, additional, De Meerleer, Gert, additional, Ost, Piet, additional, Xu, Jianfeng, additional, Razack, Azad, additional, Lim, Jasmine, additional, Teo, Soo-Hwang, additional, Newcomb, Lisa F., additional, Lin, Daniel W., additional, Fowke, Jay H., additional, Neslund-Dudas, Christine, additional, Rybicki, Benjamin A., additional, Gamulin, Marija, additional, Lessel, Davor, additional, Kulis, Tomislav, additional, Usmani, Nawaid, additional, Singhal, Sandeep, additional, Parliament, Matthew, additional, Claessens, Frank, additional, Joniau, Steven, additional, Van den Broeck, Thomas, additional, Gago-Dominguez, Manuela, additional, Castelao, Jose Esteban, additional, Martinez, Maria Elena, additional, Larkin, Samantha, additional, Townsend, Paul A., additional, Aukim-Hastie, Claire, additional, Bush, William S., additional, Aldrich, Melinda C., additional, Crawford, Dana C., additional, Srivastava, Shiv, additional, Cullen, Jennifer C., additional, Petrovics, Gyorgy, additional, Casey, Graham, additional, Roobol, Monique J., additional, Jenster, Guido, additional, van Schaik, Ron H. N., additional, Hu, Jennifer J., additional, Sanderson, Maureen, additional, Varma, Rohit, additional, McKean-Cowdin, Roberta, additional, Torres, Mina, additional, Mancuso, Nicholas, additional, Berndt, Sonja I., additional, Van Den Eeden, Stephen K., additional, Easton, Douglas F., additional, Chanock, Stephen J., additional, Cook, Michael B., additional, Wiklund, Fredrik, additional, Nakagawa, Hidewaki, additional, Witte, John S., additional, Eeles, Rosalind A., additional, Kote-Jarai, Zsofia, additional, and Haiman, Christopher A., additional
Published: 2021
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37. Association of variably methylated tumour DNA regions with overall survival for invasive lobular breast cancer

Author: Suman, Medha, primary, Dugué, Pierre-Antoine, additional, Wong, Ee Ming, additional, Joo, JiHoon Eric, additional, Hopper, John L., additional, Nguyen-Dumont, Tu, additional, Giles, Graham G., additional, Milne, Roger L., additional, McLean, Catriona, additional, and Southey, Melissa C., additional
Published: 2021
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38. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Author: Conti, David V., primary, Darst, Burcu F., additional, Moss, Lilit C., additional, Saunders, Edward J., additional, Sheng, Xin, additional, Chou, Alisha, additional, Schumacher, Fredrick R., additional, Olama, Ali Amin Al, additional, Benlloch, Sara, additional, Dadaev, Tokhir, additional, Brook, Mark N., additional, Sahimi, Ali, additional, Hoffmann, Thomas J., additional, Takahashi, Atushi, additional, Matsuda, Koichi, additional, Momozawa, Yukihide, additional, Fujita, Masashi, additional, Muir, Kenneth, additional, Lophatananon, Artitaya, additional, Wan, Peggy, additional, Le Marchand, Loic, additional, Wilkens, Lynne R., additional, Stevens, Victoria L., additional, Gapstur, Susan M., additional, Carter, Brian D., additional, Schleutker, Johanna, additional, Tammela, Teuvo L. J., additional, Sipeky, Csilla, additional, Auvinen, Anssi, additional, Giles, Graham G., additional, Southey, Melissa C., additional, MacInnis, Robert J., additional, Cybulski, Cezary, additional, Wokołorczyk, Dominika, additional, Lubiński, Jan, additional, Neal, David E., additional, Donovan, Jenny L., additional, Hamdy, Freddie C., additional, Martin, Richard M., additional, Nordestgaard, Børge G., additional, Nielsen, Sune F., additional, Weischer, Maren, additional, Bojesen, Stig E., additional, Røder, Martin Andreas, additional, Iversen, Peter, additional, Batra, Jyotsna, additional, Chambers, Suzanne, additional, Moya, Leire, additional, Horvath, Lisa, additional, Clements, Judith A., additional, Tilley, Wayne, additional, Risbridger, Gail P., additional, Gronberg, Henrik, additional, Aly, Markus, additional, Szulkin, Robert, additional, Eklund, Martin, additional, Nordström, Tobias, additional, Pashayan, Nora, additional, Dunning, Alison M., additional, Ghoussaini, Maya, additional, Travis, Ruth C., additional, Key, Tim J., additional, Riboli, Elio, additional, Park, Jong Y., additional, Sellers, Thomas A., additional, Lin, Hui-Yi, additional, Albanes, Demetrius, additional, Weinstein, Stephanie J., additional, Mucci, Lorelei A., additional, Giovannucci, Edward, additional, Lindstrom, Sara, additional, Kraft, Peter, additional, Hunter, David J., additional, Penney, Kathryn L., additional, Turman, Constance, additional, Tangen, Catherine M., additional, Goodman, Phyllis J., additional, Thompson, Ian M., additional, Hamilton, Robert J., additional, Fleshner, Neil E., additional, Finelli, Antonio, additional, Parent, Marie-Élise, additional, Stanford, Janet L., additional, Ostrander, Elaine A., additional, Geybels, Milan S., additional, Koutros, Stella, additional, Freeman, Laura E. Beane, additional, Stampfer, Meir, additional, Wolk, Alicja, additional, Håkansson, Niclas, additional, Andriole, Gerald L., additional, Hoover, Robert N., additional, Machiela, Mitchell J., additional, Sørensen, Karina Dalsgaard, additional, Borre, Michael, additional, Blot, William J., additional, Zheng, Wei, additional, Yeboah, Edward D., additional, Mensah, James E., additional, Lu, Yong-Jie, additional, Zhang, Hong-Wei, additional, Feng, Ninghan, additional, Mao, Xueying, additional, Wu, Yudong, additional, Zhao, Shan-Chao, additional, Sun, Zan, additional, Thibodeau, Stephen N., additional, McDonnell, Shannon K., additional, Schaid, Daniel J., additional, West, Catharine M. L., additional, Burnet, Neil, additional, Barnett, Gill, additional, Maier, Christiane, additional, Schnoeller, Thomas, additional, Luedeke, Manuel, additional, Kibel, Adam S., additional, Drake, Bettina F., additional, Cussenot, Olivier, additional, Cancel-Tassin, Géraldine, additional, Menegaux, Florence, additional, Truong, Thérèse, additional, Koudou, Yves Akoli, additional, John, Esther M., additional, Grindedal, Eli Marie, additional, Maehle, Lovise, additional, Khaw, Kay-Tee, additional, Ingles, Sue A., additional, Stern, Mariana C., additional, Vega, Ana, additional, Gómez-Caamaño, Antonio, additional, Fachal, Laura, additional, Rosenstein, Barry S., additional, Kerns, Sarah L., additional, Ostrer, Harry, additional, Teixeira, Manuel R., additional, Paulo, Paula, additional, Brandão, Andreia, additional, Watya, Stephen, additional, Lubwama, Alexander, additional, Bensen, Jeannette T., additional, Fontham, Elizabeth T. H., additional, Mohler, James, additional, Taylor, Jack A., additional, Kogevinas, Manolis, additional, Llorca, Javier, additional, Castaño-Vinyals, Gemma, additional, Cannon-Albright, Lisa, additional, Teerlink, Craig C., additional, Huff, Chad D., additional, Strom, Sara S., additional, Multigner, Luc, additional, Blanchet, Pascal, additional, Brureau, Laurent, additional, Kaneva, Radka, additional, Slavov, Chavdar, additional, Mitev, Vanio, additional, Leach, Robin J., additional, Weaver, Brandi, additional, Brenner, Hermann, additional, Cuk, Katarina, additional, Holleczek, Bernd, additional, Saum, Kai-Uwe, additional, Klein, Eric A., additional, Hsing, Ann W., additional, Kittles, Rick A., additional, Murphy, Adam B., additional, Logothetis, Christopher J., additional, Kim, Jeri, additional, Neuhausen, Susan L., additional, Steele, Linda, additional, Ding, Yuan Chun, additional, Isaacs, William B., additional, Nemesure, Barbara, additional, Hennis, Anselm J. M., additional, Carpten, John, additional, Pandha, Hardev, additional, Michael, Agnieszka, additional, De Ruyck, Kim, additional, De Meerleer, Gert, additional, Ost, Piet, additional, Xu, Jianfeng, additional, Razack, Azad, additional, Lim, Jasmine, additional, Teo, Soo-Hwang, additional, Newcomb, Lisa F., additional, Lin, Daniel W., additional, Fowke, Jay H., additional, Neslund-Dudas, Christine, additional, Rybicki, Benjamin A., additional, Gamulin, Marija, additional, Lessel, Davor, additional, Kulis, Tomislav, additional, Usmani, Nawaid, additional, Singhal, Sandeep, additional, Parliament, Matthew, additional, Claessens, Frank, additional, Joniau, Steven, additional, Van den Broeck, Thomas, additional, Gago-Dominguez, Manuela, additional, Castelao, Jose Esteban, additional, Martinez, Maria Elena, additional, Larkin, Samantha, additional, Townsend, Paul A., additional, Aukim-Hastie, Claire, additional, Bush, William S., additional, Aldrich, Melinda C., additional, Crawford, Dana C., additional, Srivastava, Shiv, additional, Cullen, Jennifer C., additional, Petrovics, Gyorgy, additional, Casey, Graham, additional, Roobol, Monique J., additional, Jenster, Guido, additional, van Schaik, Ron H. N., additional, Hu, Jennifer J., additional, Sanderson, Maureen, additional, Varma, Rohit, additional, McKean-Cowdin, Roberta, additional, Torres, Mina, additional, Mancuso, Nicholas, additional, Berndt, Sonja I., additional, Van Den Eeden, Stephen K., additional, Easton, Douglas F., additional, Chanock, Stephen J., additional, Cook, Michael B., additional, Wiklund, Fredrik, additional, Nakagawa, Hidewaki, additional, Witte, John S., additional, Eeles, Rosalind A., additional, Kote-Jarai, Zsofia, additional, and Haiman, Christopher A., additional
Published: 2021
Full Text: View/download PDF

39. Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

Author: Bull, Caroline J., primary, Bell, Joshua A., additional, Murphy, Neil, additional, Sanderson, Eleanor, additional, Davey Smith, George, additional, Timpson, Nicholas J., additional, Banbury, Barbara L., additional, Albanes, Demetrius, additional, Berndt, Sonja I., additional, Bézieau, Stéphane, additional, Bishop, D. Timothy, additional, Brenner, Hermann, additional, Buchanan, Daniel D., additional, Burnett-Hartman, Andrea, additional, Casey, Graham, additional, Castellví-Bel, Sergi, additional, Chan, Andrew T., additional, Chang-Claude, Jenny, additional, Cross, Amanda J., additional, de la Chapelle, Albert, additional, Figueiredo, Jane C., additional, Gallinger, Steven J., additional, Gapstur, Susan M., additional, Giles, Graham G., additional, Gruber, Stephen B., additional, Gsur, Andrea, additional, Hampe, Jochen, additional, Hampel, Heather, additional, Harrison, Tabitha A., additional, Hoffmeister, Michael, additional, Hsu, Li, additional, Huang, Wen-Yi, additional, Huyghe, Jeroen R., additional, Jenkins, Mark A., additional, Joshu, Corinne E., additional, Keku, Temitope O., additional, Kühn, Tilman, additional, Kweon, Sun-Seog, additional, Le Marchand, Loic, additional, Li, Christopher I., additional, Li, Li, additional, Lindblom, Annika, additional, Martín, Vicente, additional, May, Anne M., additional, Milne, Roger L., additional, Moreno, Victor, additional, Newcomb, Polly A., additional, Offit, Kenneth, additional, Ogino, Shuji, additional, Phipps, Amanda I., additional, Platz, Elizabeth A., additional, Potter, John D., additional, Qu, Conghui, additional, Quirós, J. Ramón, additional, Rennert, Gad, additional, Riboli, Elio, additional, Sakoda, Lori C., additional, Schafmayer, Clemens, additional, Schoen, Robert E., additional, Slattery, Martha L., additional, Tangen, Catherine M., additional, Tsilidis, Kostas K., additional, Ulrich, Cornelia M., additional, van Duijnhoven, Fränzel J. B., additional, van Guelpen, Bethany, additional, Visvanathan, Kala, additional, Vodicka, Pavel, additional, Vodickova, Ludmila, additional, Wang, Hansong, additional, White, Emily, additional, Wolk, Alicja, additional, Woods, Michael O., additional, Wu, Anna H., additional, Campbell, Peter T., additional, Zheng, Wei, additional, Peters, Ulrike, additional, Vincent, Emma E., additional, and Gunter, Marc J., additional
Published: 2020
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40. Body size and weight change over adulthood and risk of breast cancer by menopausal and hormone receptor status: a pooled analysis of 20 prospective cohort studies

Author: van den Brandt, Piet A., primary, Ziegler, Regina G., additional, Wang, Molin, additional, Hou, Tao, additional, Li, Ruifeng, additional, Adami, Hans-Olov, additional, Agnoli, Claudia, additional, Bernstein, Leslie, additional, Buring, Julie E., additional, Chen, Yu, additional, Connor, Avonne E., additional, Eliassen, A. Heather, additional, Genkinger, Jeanine M., additional, Gierach, Gretchen, additional, Giles, Graham G., additional, Goodman, Gary G., additional, Håkansson, Niclas, additional, Krogh, Vittorio, additional, Le Marchand, Loic, additional, Lee, I-Min, additional, Liao, Linda M., additional, Martinez, M. Elena, additional, Miller, Anthony B., additional, Milne, Roger L., additional, Neuhouser, Marian L., additional, Patel, Alpa V., additional, Prizment, Anna, additional, Robien, Kim, additional, Rohan, Thomas E., additional, Sawada, Norie, additional, Schouten, Leo J., additional, Sinha, Rashmi, additional, Stolzenberg-Solomon, Rachael Z., additional, Teras, Lauren R., additional, Tsugane, Shoichiro, additional, Visvanathan, Kala, additional, Weiderpass, Elisabete, additional, White, Kami K., additional, Willett, Walter C., additional, Wolk, Alicja, additional, Zeleniuch-Jacquotte, Anne, additional, and Smith-Warner, Stephanie A., additional
Published: 2020
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41. Genetic and environmental causes of variation in epigenetic aging across the lifespan

Author: Li, Shuai, primary, Nguyen, Tuong L., additional, Wong, Ee Ming, additional, Dugué, Pierre-Antoine, additional, Dite, Gillian S., additional, Armstrong, Nicola J., additional, Craig, Jeffrey M., additional, Mather, Karen A., additional, Sachdev, Perminder S., additional, Saffery, Richard, additional, Sung, Joohon, additional, Tan, Qihua, additional, Thalamuthu, Anbupalam, additional, Milne, Roger L., additional, Giles, Graham G., additional, Southey, Melissa C., additional, and Hopper, John L., additional
Published: 2020
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42. The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability

Author: Russell, Holly, primary, Kedzierska, Katarzyna, additional, Buchanan, Daniel D., additional, Thomas, Rachael, additional, Tham, Emma, additional, Mints, Miriam, additional, Keränen, Anne, additional, Giles, Graham G., additional, Southey, Melissa C., additional, Milne, Roger L., additional, Tomlinson, Ian, additional, Church, David, additional, Spurdle, Amanda B., additional, O’Mara, Tracy A., additional, and Lewis, Annabelle, additional
Published: 2020
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43. Differences in cancer survival by remoteness of residence: an analysis of data from a population-based cancer registry

Author: Afshar, Nina, primary, English, Dallas R., additional, Chamberlain, James A., additional, Blakely, Tony, additional, Thursfield, Vicky, additional, Farrugia, Helen, additional, Giles, Graham G., additional, and Milne, Roger L., additional
Published: 2020
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44. Mismatch repair gene pathogenic germline variants in a population-based cohort of breast cancer

Author: Nguyen-Dumont, Tu, primary, Steen, Jason A., additional, Winship, Ingrid, additional, Park, Daniel J., additional, Pope, Bernard J., additional, Hammet, Fleur, additional, Mahmoodi, Maryam, additional, Tsimiklis, Helen, additional, Theys, Derrick, additional, Clendenning, Mark, additional, Giles, Graham G., additional, Hopper, John L., additional, and Southey, Melissa C., additional
Published: 2020
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45. Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

Author: Papadimitriou, Nikos, primary, Dimou, Niki, additional, Tsilidis, Konstantinos K., additional, Banbury, Barbara, additional, Martin, Richard M., additional, Lewis, Sarah J., additional, Kazmi, Nabila, additional, Robinson, Timothy M., additional, Albanes, Demetrius, additional, Aleksandrova, Krasimira, additional, Berndt, Sonja I., additional, Timothy Bishop, D., additional, Brenner, Hermann, additional, Buchanan, Daniel D., additional, Bueno-de-Mesquita, Bas, additional, Campbell, Peter T., additional, Castellví-Bel, Sergi, additional, Chan, Andrew T., additional, Chang-Claude, Jenny, additional, Ellingjord-Dale, Merete, additional, Figueiredo, Jane C., additional, Gallinger, Steven J., additional, Giles, Graham G., additional, Giovannucci, Edward, additional, Gruber, Stephen B., additional, Gsur, Andrea, additional, Hampe, Jochen, additional, Hampel, Heather, additional, Harlid, Sophia, additional, Harrison, Tabitha A., additional, Hoffmeister, Michael, additional, Hopper, John L., additional, Hsu, Li, additional, María Huerta, José, additional, Huyghe, Jeroen R., additional, Jenkins, Mark A., additional, Keku, Temitope O., additional, Kühn, Tilman, additional, La Vecchia, Carlo, additional, Le Marchand, Loic, additional, Li, Christopher I., additional, Li, Li, additional, Lindblom, Annika, additional, Lindor, Noralane M., additional, Lynch, Brigid, additional, Markowitz, Sanford D., additional, Masala, Giovanna, additional, May, Anne M., additional, Milne, Roger, additional, Monninkhof, Evelyn, additional, Moreno, Lorena, additional, Moreno, Victor, additional, Newcomb, Polly A., additional, Offit, Kenneth, additional, Perduca, Vittorio, additional, Pharoah, Paul D. P., additional, Platz, Elizabeth A., additional, Potter, John D., additional, Rennert, Gad, additional, Riboli, Elio, additional, Sánchez, Maria-Jose, additional, Schmit, Stephanie L., additional, Schoen, Robert E., additional, Severi, Gianluca, additional, Sieri, Sabina, additional, Slattery, Martha L., additional, Song, Mingyang, additional, Tangen, Catherine M., additional, Thibodeau, Stephen N., additional, Travis, Ruth C., additional, Trichopoulou, Antonia, additional, Ulrich, Cornelia M., additional, van Duijnhoven, Franzel J. B., additional, Van Guelpen, Bethany, additional, Vodicka, Pavel, additional, White, Emily, additional, Wolk, Alicja, additional, Woods, Michael O., additional, Wu, Anna H., additional, Peters, Ulrike, additional, Gunter, Marc J., additional, and Murphy, Neil, additional
Published: 2020
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46. A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

Author: Escala-Garcia, Maria, primary, Abraham, Jean, additional, Andrulis, Irene L., additional, Anton-Culver, Hoda, additional, Arndt, Volker, additional, Ashworth, Alan, additional, Auer, Paul L., additional, Auvinen, Päivi, additional, Beckmann, Matthias W., additional, Beesley, Jonathan, additional, Behrens, Sabine, additional, Benitez, Javier, additional, Bermisheva, Marina, additional, Blomqvist, Carl, additional, Blot, William, additional, Bogdanova, Natalia V., additional, Bojesen, Stig E., additional, Bolla, Manjeet K., additional, Børresen-Dale, Anne-Lise, additional, Brauch, Hiltrud, additional, Brenner, Hermann, additional, Brucker, Sara Y., additional, Burwinkel, Barbara, additional, Caldas, Carlos, additional, Canzian, Federico, additional, Chang-Claude, Jenny, additional, Chanock, Stephen J., additional, Chin, Suet-Feung, additional, Clarke, Christine L., additional, Couch, Fergus J., additional, Cox, Angela, additional, Cross, Simon S., additional, Czene, Kamila, additional, Daly, Mary B., additional, Dennis, Joe, additional, Devilee, Peter, additional, Dunn, Janet A., additional, Dunning, Alison M., additional, Dwek, Miriam, additional, Earl, Helena M., additional, Eccles, Diana M., additional, Eliassen, A. Heather, additional, Ellberg, Carolina, additional, Evans, D. Gareth, additional, Fasching, Peter A., additional, Figueroa, Jonine, additional, Flyger, Henrik, additional, Gago-Dominguez, Manuela, additional, Gapstur, Susan M., additional, García-Closas, Montserrat, additional, García-Sáenz, José A., additional, Gaudet, Mia M., additional, George, Angela, additional, Giles, Graham G., additional, Goldgar, David E., additional, González-Neira, Anna, additional, Grip, Mervi, additional, Guénel, Pascal, additional, Guo, Qi, additional, Haiman, Christopher A., additional, Håkansson, Niclas, additional, Hamann, Ute, additional, Harrington, Patricia A., additional, Hiller, Louise, additional, Hooning, Maartje J., additional, Hopper, John L., additional, Howell, Anthony, additional, Huang, Chiun-Sheng, additional, Huang, Guanmengqian, additional, Hunter, David J., additional, Jakubowska, Anna, additional, John, Esther M., additional, Kaaks, Rudolf, additional, Kapoor, Pooja Middha, additional, Keeman, Renske, additional, Kitahara, Cari M., additional, Koppert, Linetta B., additional, Kraft, Peter, additional, Kristensen, Vessela N., additional, Lambrechts, Diether, additional, Le Marchand, Loic, additional, Lejbkowicz, Flavio, additional, Lindblom, Annika, additional, Lubiński, Jan, additional, Mannermaa, Arto, additional, Manoochehri, Mehdi, additional, Manoukian, Siranoush, additional, Margolin, Sara, additional, Martinez, Maria Elena, additional, Maurer, Tabea, additional, Mavroudis, Dimitrios, additional, Meindl, Alfons, additional, Milne, Roger L., additional, Mulligan, Anna Marie, additional, Neuhausen, Susan L., additional, Nevanlinna, Heli, additional, Newman, William G., additional, Olshan, Andrew F., additional, Olson, Janet E., additional, Olsson, Håkan, additional, Orr, Nick, additional, Peterlongo, Paolo, additional, Petridis, Christos, additional, Prentice, Ross L., additional, Presneau, Nadege, additional, Punie, Kevin, additional, Ramachandran, Dhanya, additional, Rennert, Gad, additional, Romero, Atocha, additional, Sachchithananthan, Mythily, additional, Saloustros, Emmanouil, additional, Sawyer, Elinor J., additional, Schmutzler, Rita K., additional, Schwentner, Lukas, additional, Scott, Christopher, additional, Simard, Jacques, additional, Sohn, Christof, additional, Southey, Melissa C., additional, Swerdlow, Anthony J., additional, Tamimi, Rulla M., additional, Tapper, William J., additional, Teixeira, Manuel R., additional, Terry, Mary Beth, additional, Thorne, Heather, additional, Tollenaar, Rob A. E. M., additional, Tomlinson, Ian, additional, Troester, Melissa A., additional, Truong, Thérèse, additional, Turnbull, Clare, additional, Vachon, Celine M., additional, van der Kolk, Lizet E., additional, Wang, Qin, additional, Winqvist, Robert, additional, Wolk, Alicja, additional, Yang, Xiaohong R., additional, Ziogas, Argyrios, additional, Pharoah, Paul D. P., additional, Hall, Per, additional, Wessels, Lodewyk F. A., additional, Chenevix-Trench, Georgia, additional, Bader, Gary D., additional, Dörk, Thilo, additional, Easton, Douglas F., additional, Canisius, Sander, additional, and Schmidt, Marjanka K., additional
Published: 2020
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47. Sustained adherence to a Mediterranean diet and physical activity on all-cause mortality in the Melbourne Collaborative Cohort Study: application of the g-formula

Author: Williamson, Elizabeth J., primary, Polak, Julia, additional, Simpson, Julie A., additional, Giles, Graham G., additional, English, Dallas R., additional, Hodge, Allison, additional, Gurrin, Lyle, additional, and Forbes, Andrew B., additional
Published: 2019
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48. Genome-wide association study of germline variants and breast cancer-specific mortality

Author: Escala-Garcia, Maria, Guo, Qi, Dörk, Thilo, Canisius, Sander, Keeman, Renske, Dennis, Joe, Beesley, Jonathan, Lecarpentier, Julie, Bolla, Manjeet K, Wang, Qin, Abraham, Jean, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Auer, Paul L, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bernstein, Leslie, Blomqvist, Carl, Boeckx, Bram, Bojesen, Stig E, Bonanni, Bernardo, Børresen-Dale, Anne-Lise, Brauch, Hiltrud, Brenner, Hermann, Brentnall, Adam, Brinton, Louise, Broberg, Per, Brock, Ian W, Brucker, Sara Y, Burwinkel, Barbara, Caldas, Carlos, Caldés, Trinidad, Campa, Daniele, Canzian, Federico, Carracedo, Angel, Carter, Brian D, Castelao, Jose E, Chang-Claude, Jenny, Chanock, Stephen J, Chenevix-Trench, Georgia, Cheng, Ting-Yuan David, Chin, Suet-Feung, Clarke, Christine L, NBCS Collaborators, Cordina-Duverger, Emilie, Couch, Fergus J, Cox, David G, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, Peter, Dunn, Janet A, Dunning, Alison M, Durcan, Lorraine, Dwek, Miriam, Earl, Helena M, Ekici, Arif B, Eliassen, A Heather, Ellberg, Carolina, Engel, Christoph, Eriksson, Mikael, Evans, D Gareth, Figueroa, Jonine, Flesch-Janys, Dieter, Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, Galle, Eva, Gapstur, Susan M, García-Closas, Montserrat, García-Sáenz, José A, Gaudet, Mia M, George, Angela, Georgoulias, Vassilios, Giles, Graham G, Glendon, Gord, Goldgar, David E, González-Neira, Anna, Alnæs, Grethe I Grenaker, Grip, Mervi, Guénel, Pascal, Haeberle, Lothar, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Hankinson, Susan, Harkness, Elaine F, Harrington, Patricia A, Hart, Steven N, Hartikainen, Jaana M, Hein, Alexander, Hillemanns, Peter, Hiller, Louise, Holleczek, Bernd, Hollestelle, Antoinette, Hooning, Maartje J, Hoover, Robert N, Hopper, John L, Howell, Anthony, Huang, Guanmengqian, Humphreys, Keith, Hunter, David J, Janni, Wolfgang, John, Esther M, Jones, Michael E, Jukkola-Vuorinen, Arja, Jung, Audrey, Kaaks, Rudolf, Kabisch, Maria, Kaczmarek, Katarzyna, Kerin, Michael J, Khan, Sofia, Khusnutdinova, Elza, Kiiski, Johanna I, Kitahara, Cari M, Knight, Julia A, Ko, Yon-Dschun, Koppert, Linetta B, Kosma, Veli-Matti, Kraft, Peter, Kristensen, Vessela N, Krüger, Ute, Kühl, Tabea, Lambrechts, Diether, Le Marchand, Loic, Lee, Eunjung, Lejbkowicz, Flavio, Li, Lian, Lindblom, Annika, Lindström, Sara, Linet, Martha, Lissowska, Jolanta, Lo, Wing-Yee, Loibl, Sibylle, Lubiński, Jan, Lux, Michael P, MacInnis, Robert J, Maierthaler, Melanie, Maishman, Tom, Makalic, Enes, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Martinez, Maria Elena, Mavroudis, Dimitrios, McLean, Catriona, Meindl, Alfons, Middha, Pooja, Miller, Nicola, Milne, Roger L, Moreno, Fernando, Mulligan, Anna Marie, Mulot, Claire, Nassir, Rami, Neuhausen, Susan L, Newman, William T, Nielsen, Sune F, Nordestgaard, Børge G, Norman, Aaron, Olsson, Håkan, Orr, Nick, Pankratz, V Shane, Park-Simon, Tjoung-Won, Perez, Jose IA, Pérez-Barrios, Clara, Peterlongo, Paolo, Petridis, Christos, Pinchev, Mila, Prajzendanc, Karoliona, Prentice, Ross, Presneau, Nadege, Prokofieva, Darya, Pylkäs, Katri, Rack, Brigitte, Radice, Paolo, Ramachandran, Dhanya, Rennert, Gadi, Rennert, Hedy S, Rhenius, Valerie, Romero, Atocha, Roylance, Rebecca, Saloustros, Emmanouil, Sawyer, Elinor J, Schmidt, Daniel F, Schmutzler, Rita K, Schneeweiss, Andreas, Schoemaker, Minouk J, Schumacher, Fredrick, Schwentner, Lukas, Scott, Rodney J, Scott, Christopher, Seynaeve, Caroline, Shah, Mitul, Simard, Jacques, Smeets, Ann, Sohn, Christof, Southey, Melissa C, Swerdlow, Anthony J, Talhouk, Aline, Tamimi, Rulla M, Tapper, William J, Teixeira, Manuel R, Tengström, Maria, Terry, Mary Beth, Thöne, Kathrin, Tollenaar, Rob AEM, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Turman, Constance, Turnbull, Clare, Ulmer, Hans-Ulrich, Untch, Michael, Vachon, Celine, van Asperen, Christi J, van den Ouweland, Ans MW, van Veen, Elke M, Wendt, Camilla, Whittemore, Alice S, Willett, Walter, Winqvist, Robert, Wolk, Alicja, Yang, Xiaohong R, Zhang, Yan, Easton, Douglas F, Fasching, Peter A, Nevanlinna, Heli, Eccles, Diana M, Pharoah, Paul DP, Schmidt, Marjanka K, Dennis, Joe [0000-0003-4591-1214], Wang, Jean [0000-0002-9139-0627], Abraham, Jean [0000-0003-0688-4807], Caldas, Carlos [0000-0003-3547-1489], Chin, Suet-Feung [0000-0001-5697-1082], Dunning, Alison [0000-0001-6651-7166], Earl, Helena [0000-0003-1549-8094], Rhenius, Valerie [0000-0003-4215-3235], Easton, Douglas [0000-0003-2444-3247], Pharoah, Paul [0000-0001-8494-732X], and Apollo - University of Cambridge Repository
Subjects: Receptors, Estrogen, Genetic Variation, Humans, Bayes Theorem, Breast Neoplasms, Female, Prognosis, Chromosomes, Human, Pair 7, White People, Genome-Wide Association Study, Proportional Hazards Models
Abstract: BACKGROUND: We examined the associations between germline variants and breast cancer mortality using a large meta-analysis of women of European ancestry. METHODS: Meta-analyses included summary estimates based on Cox models of twelve datasets using ~10.4 million variants for 96,661 women with breast cancer and 7697 events (breast cancer-specific deaths). Oestrogen receptor (ER)-specific analyses were based on 64,171 ER-positive (4116) and 16,172 ER-negative (2125) patients. We evaluated the probability of a signal to be a true positive using the Bayesian false discovery probability (BFDP). RESULTS: We did not find any variant associated with breast cancer-specific mortality at P
Published: 2019

49. Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

Author: Sud, Amit, Thomsen, Hauke, Law, Philip J., Försti, Asta, da Silva Filho, Miguel Inacio, Holroyd, Amy, Broderick, Peter, Orlando, Giulia, Lenive, Oleg, Wright, Lauren, Cooke, Rosie, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Eeles, Rosalind, Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Henderson, Brian E., Haiman, Christopher A., Benlloch, Sara, Schumacher, Fredrick R., Olama, Ali Amin Al, Berndt, Sonja I., Conti, David V., Wiklund, Fredrik, Chanock, Stephen, Stevens, Victoria L., Tangen, Catherine M., Batra, Jyotsna, Clements, Judith, Gronberg, Henrik, Schleutker, Johanna, Albanes, Demetrius, Weinstein, Stephanie, Wolk, Alicja, West, Catharine, Mucci, Lorelei, Cancel-Tassin, Géraldine, Koutros, Stella, Sorensen, Karina Dalsgaard, Maehle, Lovise, Neal, David E., Travis, Ruth C., Hamilton, Robert J., Ingles, Sue Ann, Rosenstein, Barry, Lu, Yong-Jie, Giles, Graham G., Kibel, Adam S., Vega, Ana, Kogevinas, Manolis, Penney, Kathryn L., Park, Jong Y., Stanford, Janet L., Cybulski, Cezary, Nordestgaard, Børge G., Brenner, Hermann, Maier, Christiane, Kim, Jeri, John, Esther M., Teixeira, Manuel R., Neuhausen, Susan L., De Ruyck, Kim, Razack, Azad, Newcomb, Lisa F., Lessel, Davor, Kaneva, Radka, Usmani, Nawaid, Claessens, Frank, Townsend, Paul A., Gago-Dominguez, Manuela, Roobol, Monique J., Menegaux, Florence, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, von Strandmann, Elke Pogge, Lightfoot, Tracy, Kane, Eleanor, Roman, Eve, Lake, Annette, Montgomery, Dorothy, Jarrett, Ruth F., Swerdlow, Anthony J., Engert, Andreas, Orr, Nick, Hemminki, Kari, and Houlston, Richard S.
Subjects: Science, Medizin, MEDLINE, General Physics and Astronomy, Genome-wide association study, Computational biology, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, Disease susceptibility, immune system diseases, hemic and lymphatic diseases, Classical Hodgkin lymphoma, Humans, Genetic Predisposition to Disease, Author Correction, lcsh:Science, Alleles, HLA-DP beta-Chains, Multidisciplinary, Published Erratum, General Chemistry, Hodgkin Disease, Spelling, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Key (cryptography), lcsh:Q, Psychology, Genome-Wide Association Study, HLA-DRB1 Chains
Abstract: Several susceptibility loci for classical Hodgkin lymphoma have been reported. However, much of the heritable risk is unknown. Here, we perform a meta-analysis of two existing genome-wide association studies, a new genome-wide association study, and replication totalling 5,314 cases and 16,749 controls. We identify risk loci for all classical Hodgkin lymphoma at 6q22.33 (rs9482849, P = 1.52 × 10−8) and for nodular sclerosis Hodgkin lymphoma at 3q28 (rs4459895, P = 9.43 × 10−17), 6q23.3 (rs6928977, P = 4.62 × 10−11), 10p14 (rs3781093, P = 9.49 × 10−13), 13q34 (rs112998813, P = 4.58 × 10−8) and 16p13.13 (rs34972832, P = 2.12 × 10−8). Additionally, independent loci within the HLA region are observed for nodular sclerosis Hodgkin lymphoma (rs9269081, HLA-DPB1*03:01, Val86 in HLA-DRB1) and mixed cellularity Hodgkin lymphoma (rs1633096, rs13196329, Val86 in HLA-DRB1). The new and established risk loci localise to areas of active chromatin and show an over-representation of transcription factor binding for determinants of B-cell development and immune response., Classical Hodgkin lymphoma is a cancer that originates in lymph nodes. Little is known about its genetic susceptibility. Here, the authors combined existing and new genome-wide association studies to identify risk loci for classical Hodgkin lymphoma at 6q22.33, and nodular sclerosis Hodgkin lymphoma at 3q28, 6q23.3, 10p14, 13q34, 16p13.13.
Published: 2019

50. Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

Author: Lophatananon, Artitaya, Stewart-Brown, Sarah, Kote-Jarai, Zsofia, Olama, Ali Amin Al, Garcia, Sara Benlloch, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Giles, Graham G, Fitzgerald, Liesel M, Southey, Melissa C, Pharoah, Paul, Pashayan, Nora, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Stanford, Janet L, Brenner, Hermann, Dieffenbach, Aida K, Arndt, Volker, Park, Jong Y, Lin, Hui-Yi, Sellers, Thomas, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Spurdle, Amanda, Clements, Judith A, APCB BioResource, PRACTICAL Consortium, Easton, Douglas, Eeles, Rosalind A, Muir, Kenneth, Amin Al Olama, Ali [0000-0002-7178-3431], Pharoah, Paul [0000-0001-8494-732X], Easton, Douglas [0000-0003-2444-3247], and Apollo - University of Cambridge Repository
Subjects: Male, Case-Control Studies, Humans, Prostatic Neoplasms, Gene-Environment Interaction, Middle Aged, Neoplasm Grading, Polymorphism, Single Nucleotide, Risk Assessment, APCB BioResource, Body Height, PRACTICAL consortium, Aged
Abstract: BACKGROUND: Evidence on height and prostate cancer risk is mixed, however, recent studies with large data sets support a possible role for its association with the risk of aggressive prostate cancer. METHODS: We analysed data from the PRACTICAL consortium consisting of 6207 prostate cancer cases and 6016 controls and a subset of high grade cases (2480 cases). We explored height, polymorphisms in genes related to growth processes as main effects and their possible interactions. RESULTS: The results suggest that height is associated with high-grade prostate cancer risk. Men with height >180 cm are at a 22% increased risk as compared to men with height
Published: 2018
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