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24 results on '"Shan Mei"'

6. Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables

Author

Shan, Mei, primary, Liang, Shuang, additional, Fu, Hongchen, additional, Li, Xiaoli, additional, Teng, Yu, additional, Zhao, Jingwen, additional, Liu, Yaxin, additional, Cui, Chen, additional, Chen, Li, additional, Yu, Hai, additional, Yu, Shunbang, additional, Sun, Yanling, additional, Mao, Jian, additional, Zhang, Hui, additional, Gao, Shuang, additional, and Ma, Zhenxing, additional

Published
2021
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9. Is a positive Christie-Atkinson-Munch-Peterson (CAMP) test sensitive enough for the identification of Streptococcus agalactiae?

Author

Shan-mei Wang, Dacheng Guo, Zeyu Wang, and Yu Xi

Subjects
0301 basic medicine, Gram-positive bacteria, 030106 microbiology, Pcr assay, medicine.disease_cause, DNA, Ribosomal, Polymerase Chain Reaction, Sensitivity and Specificity, DNA sequencing, CAMP test, Streptococcus agalactiae, lcsh:Infectious and parasitic diseases, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Streptococcal Infections, medicine, Humans, Standard test, lcsh:RC109-216, 030212 general & internal medicine, Bacteriological Techniques, biology, biology.organism_classification, 16S ribosomal RNA, PCR, Infectious Diseases, Parasitology, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Vagina, Female, 16S rDNA gene sequencing, Research Article
Abstract

Background For a long time, the Christie-Atkinson-Munch-Peterson (CAMP) test has been a standard test for the identification of Streptococcus agalactiae, and a positive result for S.agalactiae has been considered sensitive enough. Methods To confirm whether a positive CAMP test is a requirement for the identification of S.agalactiae, five suspected CAMP-negative S.agalactiae isolates from two hospitals, confirmed as Gram-positive and catalase-negative streptococci, were verified by the CAMP test in three batches of plates from two manufacturers and identified by the Phoenix system, MALDI-TOF MS, the PCR assay and the 16S rDNA gene sequencing. Results All five suspected strains were S.agalactiae, four of which were CAMP-negative and one of which was not S.agalactiae by the PCR assay. Conclusions A positive CAMP test was lacking sensitivity for the identification of S.agalactiae, and the question of whether the cfb gene is worthy of targeting should be further studied.

Published
2019

10. Altered resting-state brain activity in Parkinson’s disease patients with freezing of gait

Author

Tao Wu, Peipeng Liang, Linlin Gao, Piu Chan, Tao-Mian Mi, Shan-Shan Mei, and Kuncheng Li

Subjects
Male, 0301 basic medicine, medicine.medical_specialty, Cerebellum, Parkinson's disease, genetic structures, Brain activity and meditation, Rest, Thalamus, lcsh:Medicine, Brain mapping, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Basal ganglia, Humans, Medicine, Author Correction, lcsh:Science, Gait, Gait Disorders, Neurologic, Aged, Brain Mapping, Multidisciplinary, Resting state fMRI, business.industry, Putamen, lcsh:R, Brain, Parkinson Disease, Middle Aged, medicine.disease, Magnetic Resonance Imaging, 030104 developmental biology, medicine.anatomical_structure, nervous system, Case-Control Studies, Cardiology, Female, lcsh:Q, business, human activities, 030217 neurology & neurosurgery
Abstract

Freezing of gait (FOG) is a common and debilitating symptom in Parkinson’s disease (PD). The current study investigated alterations of resting-state spontaneous brain activity in PD patients with FOG. A total of 29 patients with FOG, 28 patients without FOG and 31 controls were included. All subjects underwent resting-state functional MRI, and the amplitude of low-frequency fluctuation (ALFF) was calculated to measure the spontaneous brain activity. Between-group differences and correlations with FOG severity (both subjective and objective measures) were analyzed. Compared to those without FOG, patients with FOG showed increased ALFF in right anterior cingulate cortex (ACC) and left inferior parietal lobule (IPL), as well as decreased ALFF in right superior frontal gyrus (SFG), bilateral cerebellum and left thalamus. Correlation analyses demonstrated that ALFF within the right SFG, right ACC and bilateral pallidum were positively correlated with FOG; while ALFF within the thalamus, putamen, cerebellum and sensorimotor regions were negatively correlated. Our results indicate that FOG is associated with dysfunction within frontal-parietal regions, along with increased inhibitory outputs from basal ganglia. Additionally, altered activity of cerebellum implicates its role in the pathophysiology of FOG. These findings provide further insight into the underlying neural mechanisms of FOG in PD patients.

Published
2017

14. Amphotericin B Inhibits Enterovirus 71 Replication by Impeding Viral Entry

Author

Shan Mei, Shan Cen, Jianwei Wang, Fengwen Xu, Lijuan Yin, Siqi Hu, Lili Ren, Qi Jin, Fei Guo, Zhendong Zhao, Chen Liang, Jian Li, Bin Ai, Ying Wang, Tingting Liu, and Xiaoxiao Zhao

Subjects
0301 basic medicine, medicine.drug_class, media_common.quotation_subject, 030106 microbiology, Antibiotics, Virus Replication, Article, Microbiology, 03 medical and health sciences, Viral entry, Amphotericin B, Cell Line, Tumor, Enterovirus Infections, medicine, Enterovirus 71, Humans, Internalization, media_common, Multidisciplinary, biology, HEK 293 cells, Virus Internalization, biology.organism_classification, Virology, Enterovirus A, Human, 030104 developmental biology, Viral replication, Cell culture, medicine.drug
Abstract

Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease that leads to cardiopulmonary complications and death in young children. There is thus an urgent need to find new treatments to control EV71 infection. In this study, we report potent inhibition of EV71 by a polyene antibiotic Amphotericin B. Amphotericin B profoundly diminished the expression of EV71 RNA and viral proteins in the RD cells and the HEK293 cells. As a result, EV71 production was inhibited by Amphotericin B with an EC50 (50% effective concentration) of 1.75 μM in RD cells and 0.32 μM in 293 cells. In addition to EV71, EV68 was also strongly inhibited by Amphotericin B. Results of mechanistic studies revealed that Amphotericin B targeted the early stage of EV71 infection through impairing the attachment and internalization of EV71 by host cells. As an effective anti-fungi drug, Amphotericin B thus holds the promise of formulating a novel therapeutic to treat EV71 infection.

Published
2016

15. Highly robust crystalsome via directed polymer crystallization at curved liquid/liquid interface

Author

Wenda Wang, Hiroshi Jinnai, Takeshi Higuchi, Christopher Y. Li, Tian Zhou, Hao Qi, Shan Mei, and Lin Han

Subjects
Materials science, Science, Crystallization of polymers, General Physics and Astronomy, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Micelle, Article, General Biochemistry, Genetics and Molecular Biology, law.invention, law, Crystallization, Curved space, chemistry.chemical_classification, Multidisciplinary, Vesicle, General Chemistry, Polymer, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Miniemulsion, chemistry, Polymersome, 0210 nano-technology
Abstract

Lipids and amphiphilic block copolymers spontaneously self-assemble in water to form a plethora of micelles and vesicles. They are typically fluidic in nature and often mechanically weak for applications such as drug delivery and gene therapeutics. Mechanical properties of polymeric materials could be improved by forming crystalline structures. However, most of the self-assembled micelles and vesicles have curved surfaces and precisely tuning crystallization within a nanoscale curved space is challenging, as the curved geometry is incommensurate with crystals having three-dimensional translational symmetry. Herein, we report using a miniemulsion crystallization method to grow nanosized, polymer single-crystal-like capsules. We coin the name crystalsome to describe this unique structure, because they are formed by polymer lamellar crystals and their structure mimics liposomes and polymersomes. Using poly(L-lactic acid) (PLLA) as the model polymer, we show that curved water/p-xylene interface formed by the miniemulsion process can guide the growth of PLLA single crystals. Crystalsomes with the size ranging from ∼148 nm to over 1 μm have been formed. Atomic force microscopy measurement demonstrate a two to three orders of magnitude increase in bending modulus compared with conventional polymersomes. We envisage that this novel structure could shed light on investigating spherical crystallography and drug delivery., Self-assemblies of polymers to form polymersomes in solution can be used as carriers for drug delivery, but it is challenging to control polymer crystallization to improve their mechanical stability. Here, Wang et al. show the formation of nanosized crystalsomes composed of polymer lamellar single crystals.

Published
2016

16. Erratum: Identification of a nanobody specific to a human pulmonary surfactant protein A

Author

He, Xian, primary, Wang, Shan-Mei, additional, Yin, Zhao Fang, additional, Zhao, Meng-Meng, additional, Li, Nan, additional, Yu, Feng, additional, Wang, Liu-Sheng, additional, Hu, Yang, additional, Du, Yu-Kui, additional, Du, Shan-Shan, additional, Li, Yan, additional, Wei, Ya-Ru, additional, Chen, Shan-Shan, additional, He, Jian-Hua, additional, Weng, Dong, additional, and Li, Hui-Ping, additional

Published
2017
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17. Identification of a nanobody specific to human pulmonary surfactant protein A

Author

He, Xian, primary, Wang, Shan-Mei, additional, Fang Yin, Zhao, additional, Zhao, Meng-Meng, additional, Li, Nan, additional, Yu, Feng, additional, Wang, Liu-Sheng, additional, Hu, Yang, additional, Du, Yu-Kui, additional, Du, Shan-Shan, additional, Li, Yan, additional, Wei, Ya-Ru, additional, Chen, Shan-Shan, additional, He, Jian-Hua, additional, Weng, Dong, additional, and Li, Hui-Ping, additional

Published
2017
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18. Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities

Author

Yang, Li-yun, primary, Liu, Xiao-fang, additional, Yang, Yang, additional, Yang, Lin-lin, additional, Liu, Kai-wen, additional, Tang, Yu-bo, additional, Zhang, Min, additional, Tan, Min-jia, additional, Cheng, Shan-mei, additional, Xu, Ye-chun, additional, Yang, Huai-yu, additional, Liu, Zhi-jie, additional, Song, Gao-jie, additional, and Huang, Wei, additional

Published
2016
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22. Isolation and characterization of ZZ1, a novel lytic phage that infects Acinetobacter baumannii clinical isolates

Author

Jin, Jing, primary, Li, Zhen-Jiang, additional, Wang, Shu-Wei, additional, Wang, Shan-Mei, additional, Huang, De-Hai, additional, Li, Ya-Hui, additional, Ma, Yun-Yun, additional, Wang, Jin, additional, Liu, Fang, additional, Chen, Xiang-Dong, additional, Li, Guang-Xing, additional, Wang, Xiao-Ting, additional, Wang, Zhong-Quan, additional, and Zhao, Guo-Qiang, additional

Published
2012
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