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1. Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy.

Author

Werter, Inge M., Schneiders, Famke L., Scotet, Emmanuel, Verheul, Henk M.W., de Gruijl, Tanja D., and van der Vliet, Hans J.

Subjects
*IMMUNOTHERAPY, *T cells, *ANTIGENS, *IMMUNE response, *MEMBRANE proteins
Abstract

CD1d-restricted invariant natural killer T cells (iNKT) constitute an important immunoregulatory T-cell subset involved in the induction of antitumor immune responses. Here, we provide a view on the recent observation that Vγ9Vδ2-T cells, through trogocytosis of CD1d-containing membrane fragments, have the capacity to act as antigen presenting cells for iNKT. [ABSTRACT FROM AUTHOR]

Published
2014
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