1. Human IgG antibody response toAedes aegyptiNterm-34 kDa salivary peptide as an indicator to identify areas at high risk for dengue transmission: a retrospective study in urban settings of Vientiane city, Lao PDR
- Author
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Bounpone Sidavong, Audrey Dubot-Pérès, Emmanuel Elanga Ndille, François Mouchet, Florence Fournet, Sylvie Cornelie, Franck Remoue, and Souleymane Doucoure
- Subjects
Adult ,Male ,Risk ,medicine.medical_specialty ,Endemic Diseases ,Urban Population ,Enzyme-Linked Immunosorbent Assay ,Aedes aegypti ,Dengue virus ,medicine.disease_cause ,Dengue fever ,Dengue ,Aedes ,medicine ,Dengue transmission ,Animals ,Humans ,Seroprevalence ,Cities ,Salivary Proteins and Peptides ,Child ,Retrospective Studies ,Gynecology ,biology ,Urbanization ,Public Health, Environmental and Occupational Health ,biology.organism_classification ,medicine.disease ,Insect Vectors ,Flavivirus ,Infectious Diseases ,Antibody response ,Laos ,Child, Preschool ,Immunoglobulin G ,Antibody Formation ,Female ,Parasitology ,Biomarkers - Abstract
Objective Using human IgG antibody response to the Aedes Nterm-34 kDa salivary peptide as an indicator of human exposure to Aedes bites in surveying exposed populations from areas at risk of dengue virus (DENV) transmission in urban settings of Vientiane city, Lao PDR. Methods Enzyme-linked immunosorbent assay tests were performed to measure the IgG response to Nterm-34 kDa peptide in blood samples collected within a flavivirus seroprevalence survey carried out in 2006 including 3558 randomly selected individuals. The level of IgG response to the Nterm-34 kDa peptide in individuals was analysed in relation to the level of urbanisation of the individual's residence, areas that presented significant differences in the prevalence of recent DENV infection. Results No differences were observed in the anti-Nterm-34 kDa IgG level between DENV-positive and DENV-negative individuals. However, the level of specific IgG response was higher among individuals living in slightly urbanised neighbourhoods than among those in more highly urbanised areas (P
- Published
- 2014