1. Pollen derived low molecular compounds enhance the human allergen specific immune responsein vivo
- Author
-
Adam Chaker, Heidrun Behrendt, M McIntyre, Liliana Cifuentes, Murat Bas, Carsten B. Schmidt-Weber, Stefanie Gilles‐Stein, Jan Gutermuth, Arnd Petersen, Isabelle Beck, Claudia Traidl-Hoffmann, Skin function and permeability, and Surgical clinical sciences
- Subjects
medicine.medical_treatment ,Mucous membrane of nose ,medicine.disease_cause ,Immunoglobulin E ,Cell Degranulation ,0302 clinical medicine ,Allergen ,immune system diseases ,Immunology and Allergy ,Betula ,Medicine(all) ,respiratory system ,Basophils ,pollen-associated lipid mediator ,Pollen ,Inflammation Mediators ,Symptom Assessment ,medicine.symptom ,Nasal Provocation Tests ,prick test ,Immunology ,Low molecular weight pollen fraction ,Biology ,Nasal congestion ,Nasal provocation test ,Immunomodulation ,03 medical and health sciences ,Th2 Cells ,Immune system ,nasal challenge ,otorhinolaryngologic diseases ,medicine ,Humans ,ddc:610 ,Skin Tests ,rhinorrhea ,Plant Extracts ,Interleukin-8 ,Immunity ,Rhinitis, Allergic, Seasonal ,Allergens ,respiratory tract diseases ,Molecular Weight ,Nasal Mucosa ,030228 respiratory system ,biology.protein ,030215 immunology - Abstract
BACKGROUND: Besides allergens, pollen release bioactive, low molecular weight compounds that modulate and stimulate allergic reactions. Clinical relevance of these substances hasn't been investigated to date. OBJECTIVE: To elucidate the effect of a non-allergenic, low molecular weight factors from aqueous birch pollen extracts (Bet-APE
- Published
- 2016