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399 results on '"sirtuin 1"'

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1. Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1

2. Astragaloside IV Alleviates Acute Hepatic Injury by Regulating Macrophage Polarization and Pyroptosis via Activation of the AMPK/SIRT1 Signaling Pathway.

3. Hypoxia: Role of SIRT1 and the protective effect of resveratrol in ovarian function

4. QKI 6 ameliorates CIRI through promoting synthesis of triglyceride in neuron and inhibiting neuronal apoptosis associated with SIRT1‐PPARγ‐PGC‐1α axis

5. Ursolic acid enhances the effect of exercise training on vascular aging by reducing oxidative stress in aged type 2 diabetic rats

6. <scp>SIRT1</scp> targeted by <scp>miR</scp> ‐211‐5p regulated proliferation and apoptosis of Dex‐treated growth plate chondrocytes via mediating <scp>SOX2</scp>

7. Resveratrol attenuates behavioural impairment associated with learning and memory in rats with diabetes induced by a high‐fat diet and streptozotocin

8. Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting <scp>AMPK</scp> ‐mediated mesenchymal epithelial transition and oxidative stress

9. Resveratrol, novel application by preconditioning to attenuate myocardial ischemia/reperfusion injury in mice through regulate <scp>AMPK</scp> pathway and autophagy level

10. β-lapachone protects against doxorubicin-induced hepatotoxicity through modulation of NAD + /SIRT-1/FXR/p-AMPK/NF-kB and Nrf2 signaling axis.

11. Effects of bis (2‐butoxyethyl) phthalate on adrenocortical function in male rats in puberty partially via down‐regulating <scp>NR5A1</scp> / <scp>NR4A1</scp> / <scp>NR4A2</scp> pathways

12. Resveratrol ameliorates muscle atrophy in chronic kidney disease via the axis of SIRT1/FoxO1

13. SIRT1 inhibition‐induced senescence as a strategy to prevent prostate cancer progression

14. SRT1720 induces SIRT1‐independent cell death in adult T‐cell leukemia/lymphoma

15. Circ‐Sirt1 inhibits vascular smooth muscle cells proliferation via the c‐Myc/cyclin B1 axis

16. Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice

17. The deacetylation of Foxk2 by Sirt1 reduces chemosensitivity to cisplatin

18. Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO‐1 pathways

19. <scp>SIRT1</scp> / <scp>mTOR</scp> pathway‐mediated autophagy dysregulation promotes Pb‐induced hepatic lipid accumulation in <scp>HepG2</scp> cells

20. Follicle‐stimulating hormone regulates glycolysis of water buffalo follicular granulosa cells through AMPK/SIRT1 signalling pathway

21. Resveratrol reduces DRP1‐mediated mitochondrial dysfunction via the SIRT1‐PGC1α signaling pathway in manganese‐induced nerve damage in mice

22. Hyperbaric oxygen via mediating SIRT1‐induced deacetylation of HMGB1 improved cReperfusion inj/reperfusion injury

23. Activation of <scp>FMS</scp> ‐like tyrosine kinase 3 protects against isoprenaline‐induced cardiac hypertrophy by improving autophagy and mitochondrial dynamics

24. LincRNA‐p21 alleviates atherosclerosis progression through regulating the miR‐221/SIRT1/Pcsk9 axis

25. Fenofibrate inhibits hypoxia‐inducible factor‐1 alpha and carbonic anhydrase expression through activation of AMP‐activated protein kinase/ <scp>HO</scp> ‐1/Sirt1 pathway in glioblastoma cells

26. Ferulic acid suppresses interleukin‐1β‐induced degeneration of chondrocytes isolated from patients with osteoarthritis through the SIRT1/AMPK/PGC‐1α signaling pathway

27. Melatonin attenuates prostatic inflammation and pelvic pain via Sirt1‐dependent inhibition of the NLRP3 inflammasome in an EAP mouse model

28. The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets

29. Novel pathophysiological roles of α‐synuclein in age‐related vascular endothelial dysfunction

30. Mechanical stress‐caused chondrocyte dysfunction and cartilage injury can be attenuated by dioscin via activating sirtuin1/forkhead box O1

31. p300 arrests intervertebral disc degeneration by regulating the <scp>FOXO3</scp> /Sirt1/Wnt/β‐catenin axis

32. Sirt1 overexpression improves senescence‐associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL‐11 transcription

33. Downregulation of miR‐34c‐5p alleviates chronic intermittent hypoxia‐induced myocardial damage by targeting sirtuin 1

34. Glycogen accumulation in adipocyte precursors from elderly and obese subjects triggers inflammation via <scp>SIRT1</scp> /6 signaling

35. hsa_circ_0115355 promotes pancreatic β‐cell function in patients with type 2 diabetes through the <scp>miR</scp> ‐145/ <scp>SIRT1</scp> axis

36. Cerebroprotection by dioscin after experimental subarachnoid haemorrhage via inhibiting NLRP3 inflammasome through SIRT1‐dependent pathway

37. 5‐Aminolevulinic acid/sodium ferrous citrate enhanced the antitumor effects of programmed cell death‐ligand 1 blockade by regulation of exhausted T cell metabolism in a melanoma model

38. Administration of isoliquiritigenin prevents nonalcoholic fatty liver disease through a novel <scp>IQGAP2‐CREB‐SIRT1</scp> axis

39. FGF19 protects skeletal muscle against obesity‐induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT‐1/PGC‐α pathway

40. Effects of dietary ferulic acid supplementation on growth performance and skeletal muscle fiber type conversion in weaned piglets

41. Acylated ghrelin protects against doxorubicin‐induced nephropathy by activating silent information regulator 1

42. TNFα expression by Porphyromonas gingivalis ‐stimulated macrophages relies on Sirt1 cleavage

43. Sirtuin 1 promotes autophagy and proliferation of endometrial cancer cells by reducing acetylation level of LC3

44. Mangiferin prevents myocardial infarction‐induced apoptosis and heart failure in mice by activating the Sirt1/FoxO3a pathway

45. Empagliflozin alleviates ethanol‐induced cardiomyocyte injury through inhibition of mitochondrial apoptosis via a SIRT1/PTEN/Akt pathway

46. Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/NRF2/Prx2/ASK1/p38 after traumatic brain injury in mice

47. Late intervention in the remnant kidney model attenuates proteinuria but not glomerular filtration rate decline

48. Antioxidant Sirt1/Akt axis expression in resveratrol pretreated adipose‐derived stem cells increases regenerative capability in a rat model with cardiomyopathy induced by diabetes mellitus

49. Puerarin prevents cadmium‐induced disorder of testicular lactic acid metabolism in rats by activating 5′ <scp>AMP</scp> ‐activated protein kinase ( <scp>AMPK</scp> )/sirtuin 1 ( <scp>SIRT1</scp> ) signaling pathway

50. Foetal recapitulation of nutrient surplus signalling by O-GlcNAcylation and the failing heart.

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