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Your search keyword '"Guo, Chang"' showing total 6 results
Start Over Author "Guo, Chang" Topic carbenes Publisher wiley-blackwell
6 results on '"Guo, Chang"'

1. N-Heterocyclic Carbene Catalyzed Formal [3+2] Annulation Reaction of Enals: An Efficient Enantioselective Access to Spiro-Heterocycles.

Author

Guo, Chang, Schedler, Michael, Daniliuc, Constantin G., and Glorius, Frank

Subjects
*HETEROCYCLIC compounds, *CARBENES, *ANNULATION, *ENANTIOSELECTIVE catalysis, *ALDEHYDES, *CHEMICAL derivatives, *ENANTIOMERIC purity
Abstract

A highly enantioselective N-heterocyclic carbene (NHC) catalyzed formal [3+2] annulation of α,β-unsaturated aldehydes with azaaurones or aurone generating spiro-heterocycles has been developed. The protocol represents a unique NHC-activation-based approach to access spiro-heterocyclic derivatives bearing a quaternary stereogenic center with high optical purity (up to 95 % ee). [ABSTRACT FROM AUTHOR]

Published
2014
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2. ChemInform Abstract: Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations.

Author

Guo, Chang, Fleige, Mirco, Janssen‐Mueller, Daniel, Daniliuc, Constantin G., and Glorius, Frank

Subjects
*HETEROCYCLIC compound derivatives, *CARBENES, *PALLADIUM catalysts, *ENANTIOSELECTIVE catalysis, *ANNULATION, *REGIOSELECTIVITY (Chemistry)
Abstract

The regioselective title reaction between vinyl benzoxazinanones and aryl, alkenyl or alkyl substituted enals delivers benzazepine derivatives in high yields, with high diastereo- and excellent enantioselectivities. [ABSTRACT FROM AUTHOR]

Published
2016
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4. ChemInform Abstract: N-Heterocyclic Carbene Catalyzed Switchable Reactions of Enals with Azoalkenes: Formal [4 + 3] and [4 + 1] Annulations for the Synthesis of 1,2-Diazepines and Pyrazoles.

Author

Guo, Chang, Sahoo, Basudev, Daniliuc, Constantin G., and Glorius, Frank

Subjects
*DIAZEPINES, *HETEROCYCLIC compound derivatives, *CARBENES, *CHEMICAL reactions, *ALKENES, *ANNULATION, *PYRAZOLES, *HETEROCYCLIC compounds synthesis
Abstract

Various 1,2-diazepine derivatives are synthesized by regio- and enantioselective formal [4 + 3] annulation reaction between enals and in situ formed azoalkenes. [ABSTRACT FROM AUTHOR]

Published
2015
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5. ChemInform Abstract: N-Heterocyclic Carbene Catalyzed Formal [3 + 2] Annulation Reaction of Enals: An Efficient Enantioselective Access to Spiro-Heterocycles.

Author

Guo, Chang, Schedler, Michael, Daniliuc, Constantin G., and Glorius, Frank

Subjects
*CARBENES, *HETEROCYCLIC compounds, *ANNULATION, *ENANTIOSELECTIVE catalysis, *SPIRO compounds, *ALDEHYDES
Abstract

The process is applied to various azaaurones and α,β-unsaturated aldehydes to afford indole-based spiro compounds with a quaternary stereogenic center. [ABSTRACT FROM AUTHOR]

Published
2015
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6. N′-[(1 E)-(5-Chloro-2-hydroxyphenyl)(phenyl)methylene]-4-methoxybenzohydrazide.

Author

Jian-Guo Chang and Rong-Dong Yang

Subjects
*CARBENES, *AROMATIC compounds, *CHEMICAL structure, *CRYSTALLIZATION, *ORGANIC chemistry, *CHEMISTRY
Abstract

The title compound, C21H17ClN2O3, displays a trans configuration with respect to the C=N double bond. The crystal structure is stabilized by intramolecular O—H...N and intermolecular C—H...O hydrogen bonds. [ABSTRACT FROM AUTHOR]

Published
2007
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