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Comprehensive Summary We present a facile synthetic strategy to create mesoporous Cu2O nanocrystals with tunable pore structures and surface functional groups of amine derivatives for efficient and preferable electrochemical conversion of CO2 into ethylene. The structural characteristics of these Cu2O nanocrystals can be manipulated using a set of amine derivatives, such as pyridine, 4,4'‐bipyridine, and hexamethylenetetramine, during the oxidative etching process of Cu nanocrystals by bubbling gaseous oxygen in N,N‐dimethylformamide solution. These amine derivatives not only serve as surface functional groups but also significantly affect the resulting pore structures. The synergistic effect of pore structure confinement and surface amine functionalization leads to the superb Faradaic efficiency (FE) of 51.9% for C2H4, respectively, together with the C2H4 partial current density of –209.4 mA·cm−2 at –0.8 V vs. reversible hydrogen electrode (RHE). The relatively high selectivity towards C2H4 was investigated using DFT simulations, where 4,4'‐bipyridine functionalized Cu2O seemed to favor the C2H4 formation with the low free energy of the intermediates. This study provides a feasible strategy to manipulate the pore structure and surface functionalization of mesoporous Cu2O nanocrystals by regulating the oxidative etching process, which sheds light on the rational preparation of high‐performance CO2RR electrocatalysts. [ABSTRACT FROM AUTHOR]

Fluorous gold nanoparticle ( Fluo-NP), i.e. gold nanoparticle covered by fluorous ponytail (C8F17-) was prepared and found to self-assemble into supra-structures covered by carbohydrates (named supraF-NP), due to the strong fluorous interaction. More importantly, the re-dispersed supraF-NP (diameter around 200 nm) in water provided an alternative strategy to detect carbohydrate-protein interaction in solution by naked eye. [ABSTRACT FROM AUTHOR]

Aim: The review is to explore the connection between gestational hypertension diseases (GHD) and small for gestational age (SGA) in twin pregnancies. Methods: According to the recommendations of PRISMA, relevant studies were systematically searched through PubMed, Web of Science, Cochrane Library, Embase from inception until January 16, 2022. Subgroup analysis was performed according to chorionicity and diagnostic criteria of SGA. Odds ratios (OR) were assessed to judge the link between GHD and SGA in twin pregnant women. A random‐effect model was used to estimate the pooled hazard ratio when there was significant heterogeneity (I2 > 50%); otherwise, a fixed‐effect model was conducted. Results: Seven articles containing 470 589 twin pregnant women were included. The increased risk of SGA was connected to the twin pregnancies complicated with GHD (OR = 1.57, 95% confidence interval [CI] = 1.10–2.24, p = 0.01). After subgroup analysis, the connection between SGA and GHD had no statistical significance (OR = 1.17, 95% CI = 0.95–1.44, p = 0.14) when the enrolled studies using the SGA diagnosis referred to singleton birth weight, but significant (OR = 2.14, 95% CI = 1.77–2.60, p<0.001) in the group using the SGA diagnosis referred to twin birth weight. Stratified by chorionicity, SGA was relevant to GHD in the dichorionic (DC) group (OR = 1.68, 95% CI = 1.17–2.42, p = 0.005), while not in the monochorionic (MC) group (OR = 1.68, 95% CI = 0.93–3.03, p = 0.09). More future articles are warranted to confirm these outcomes. Conclusions: Our review demonstrated that GHD in DC twin pregnancies was related to an enlarged risk of SGA. Two SGA diagnosis references led to different results. Twin pregnancies complicated with GHD were at significantly higher risk of SGA when twin birth weight reference was used. [ABSTRACT FROM AUTHOR]

CD38 is a multifunctional receptor and enzyme present on the surface of B lymphocytes, which can induce B lymphocytes proliferation and apoptosis by crosslinking related cytokines to affect the function of B cells, thus affecting immune regulation in humans and promoting tumorigenesis. The level of CD38 expression in B cells has become an important factor in the clinical diagnosis, treatment, and prognosis of malignant tumors and other related diseases. Therefore, studying the relationship between CD38 expression on the surface of B cells and the occurrence of the disease is of great significance for elucidating its association with disease pathogenesis and the clinical targeted therapy. In this paper, we review the effects of CD38 on B‐cell activation, proliferation, and differentiation, and elaborate the functional role and mechanism of CD38 expression on B cells. We also summarize the relationship between the level of CD38 expression on the surface of B cells and the diagnosis, treatment, and prognosis of various diseases, as well as the potential use of targeted CD38 treatment for related diseases. This will provide an important theoretical basis for the scientific research and clinical diagnosis and treatment of B‐cell‐related diseases. [ABSTRACT FROM AUTHOR]