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Second career preservice teachers' perceptions about the out-of-field teaching phenomenon might influence career decisions, such as retention and attrition. A target group of 133 second career graduating Master of Teaching students voluntarily participated in this mixed method study which offered findings through analysed open and Likert-scale questions and semi-structured interview data. The pilot offers new information about second career preservice teachers' perceptions about their possible involvement in out-of-field teaching practices and the phenomenon's implications for capabilities, skills knowledge, self-efficacy, support needs and professional identity. A critical reflection on quality teaching and teacher training programs, and preparation for the teaching profession form the foundation for further research in this field. The analyses further stimulate a deeper understanding of the future second career teaching workforce and perceptions of support resources.

Second career preservice teachers’ perceptions about the out-of-field teaching phenomenon might influence career decisions, such as retention and attrition. A target group of 133 second career graduating Master of Teaching students voluntarily participated in this mixed method study which offered findings through analysed open and Likert-scale questions and semi-structured interview data. The pilot offers new information about second career preservice teachers’ perceptions about their possible involvement in out-of-field teaching practices and the phenomenon’s implications for capabilities, skills knowledge, self-efficacy, support needs and professional identity. A critical reflection on quality teaching and teacher training programs, and preparation for the teaching profession form the foundation for further research in this field. The analyses further stimulate a deeper understanding of the future second career teaching workforce and perceptions of support resources. Practitioner Notes 1. What is the focus of development (capabilities, skills, knowledge)? 2. What is the role of reflective practice (in situ, post) for individual staff (reflecting on personal development, reflecting on the field of academic / faculty development)? 3. How do we resource the development of teaching practice? 4. How understanding teaching practice and the out-of-field teaching phenomenon will contribute to improving academics’ views regarding the preparation of preservice teachers for workplace challenges and practice teaching 5. How can the information from this investigation develop teaching practice linked to possible out-of-field teaching positions to improve preparedness and support? 6. The pilot unveils information to support academics’ critical reflection on the alignment of current workplace concerns to the reality of preservice teacher preparation. [ABSTRACT FROM AUTHOR]

Clinical and biochemical diversity of Parkinson's disease (PD) and numerous demographic, clinical, and pathological measures influencing cognitive function and its decline in PD create problems with the determination of effects of individual measures on cognition in PD. This is particularly the case where these measures significantly interrelate with each other producing intricate networks of direct and indirect effects on cognition. Here, we use generalized structural equation modelling (GSEM) to identify and characterize significant paths for direct and indirect effects of 14 baseline measures on global cognition in PD at baseline and at 4 years later. We consider 269 drug-naïve participants from the Parkinson's Progression Marker Initiative database, diagnosed with idiopathic PD and observed for at least 4 years after baseline. Two GSEM networks are derived, highlighting the possibility of at least two different molecular pathways or two different PD sub-types, with either CSF p-tau181 or amyloid beta (1–42) being the primary protein variables potentially driving progression of cognitive decline. The models provide insights into the interrelations between the 14 baseline variables, and determined their total effects on cognition in early PD. High CSF amyloid concentrations (> 500 pg/ml) are associated with nearly full protection against cognitive decline in early PD in the whole range of baseline age between 40 and 80 years, and irrespectively of whether p-tau181 or amyloid beta (1–42) are considered as the primary protein variables. The total effect of depression on cognition is shown to be strongly amplified by PD, but not at the time of diagnosis or at prodromal stages. CSF p-tau181 protein could not be a reliable indicator of cognitive decline because of its significantly heterogeneous effects on cognition. The outcomes will enable better understanding of the roles of the clinical and pathological measures and their mutual effects on cognition in early PD. [ABSTRACT FROM AUTHOR]

We develop a computationally efficient method for the theoretical analysis of thermophoresis of nanoparticles and adatoms on crystalline surfaces (thermal tweezers) for efficient parallel nanofabrication. The analysis of surface diffusion of particles or adatoms in the presence of strong temperature gradients is conducted through the direct determination of probability distributions for diffusing particles, using the numerical solution of the Smoluchowski diffusion equation with varying (temperature-dependent) diffusion constant. The local values of the diffusion constant are determined from the Fokker–Planck equation for the considered crystalline potential of the substrate and local temperature. Steady-state and nonsteady-state particle distributions on the surface are obtained and analyzed in the presence of optically-induced strong temperature gradients. Detailed comparison of this approach with the previously obtained results from the Monte Carlo simulations of the Langevin equation is conducted, demonstrating high computational efficiency, and accuracy of the new method in the high-friction regime. Applicability conditions for the developed method are also determined and discussed. [ABSTRACT FROM AUTHOR]

We conduct the detailed numerical investigation of a nanomanipulation and nanofabrication technique—thermal tweezers with dynamic evolution of surface temperature, caused by absorption of interfering laser pulses in a thin metal film or any other absorbing surface. This technique uses random Brownian forces in the presence of strong temperature modulation (surface thermophoresis) for effective manipulation of particles/adatoms with nanoscale resolution. Substantial redistribution of particles on the surface is shown to occur with the typical size of the obtained pattern elements of ∼100 nm, which is significantly smaller than the wavelength of the incident pulses used (532 nm). It is also demonstrated that thermal tweezers based on surface thermophoresis of particles/adatoms are much more effective in achieving permanent high maximum-to-minimum concentration ratios than bulk thermophoresis, which is explained by the interaction of diffusing particles with the periodic lattice potential on the surface. Typically required pulse regimes including pulse lengths and energies are also determined. The approach is applicable for reproducing any holographically achievable surface patterns, and can thus be used for engineering properties of surfaces including nanopatterning and design of surface metamaterials. [ABSTRACT FROM AUTHOR]

Highlights: [•] Higher faecal cortisol levels were recorded during drought compared to post-flood. [•] Drought diets were mainly composed of species with high leaf moisture. [•] Low minimum temperatures increased faecal cortisol concentrations. [ABSTRACT FROM AUTHOR]

Recent research has shown that the ecology of stress has hitherto been neglected, but it is in fact an important influence on the distribution and numbers of wild vertebrates. Environmental changes have the potential to cause physiological stress that can affect population dynamics. Detailed information on the influence of environmental variables on glucocorticoid levels (a measure of stress) at the trailing edge of a species’ distribution can highlight stressors that potentially threaten species and thereby help explain how environmental challenges, such as climate change, will affect the survival of these populations. Rainfall determines leaf moisture and/or nutritional content, which in turn impacts on cortisol concentrations. We show that higher faecal cortisol metabolite (FCM) levels in koala populations at the trailing arid edge of their range in southwestern Queensland are associated with lower rainfall levels (especially rainfall from the previous two months), indicating an increase in physiological stress when moisture levels are low. These results show that koalas at the semi-arid, inland edge of their geographic range, will fail to cope with increasing aridity from climate change. The results demonstrate the importance of integrating physiological assessments into ecological studies to identify stressors that have the potential to compromise the long-term survival of threatened species. This finding points to the need for research to link these stressors to demographic decline to ensure a more comprehensive understanding of species’ responses to climate change. [ABSTRACT FROM AUTHOR]

Objective: To demonstrate evidence of possible major impacts of psychological stress and psychosomatic interventions on myeloproliferative blood disorders and develop new approaches for the unification and quantified analysis of stress and psychosomatic treatments. Methods: This 3.5- year longitudinal study was based upon the regular blood tests of a person with myelofibrosis who experienced severe and repeated work-related psychological stress and was subjected to psychosomatic treatment in the form of regular (∼4 h per day) self-hypnosis sessions. Statistical data analysis was conducted on the basis of an introduced concept of generalized stress that mathematically unifies psychological stress and psychosomatic treatment. Results: Severe stress and psychosomatic treatment were statistically shown to have a major (dominant) impact on blood platelet counts well described by an exponential dependence on cumulative levels of generalized stress. The typical relaxation time for the impacts of both stress and treatment was shown to be ∼2 months. Only ∼12% of the total variation in platelet counts could be attributed to factors other than psychological stress and psychosomatic treatment. The psychosomatic intervention resulted in a consistent reduction of high platelet counts from ∼1,400 × 109 l-1 to approximately the middle of the normal range, with other blood parameters being either approximately stable or showing indications of a strengthening immune system. Conclusions: Our findings give hope for a possible development of psychosomatic treatments of at least some blood disorders. They also indicate a highly instrumental role of platelets in the quantified analysis of stress, psychosomatic interventions, and their neuroimmunological pathways. Copyright © 2011 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

In this paper, evolution of the size distribution of fine and ultra-fine particles emitted from vehicles on a busy road is investigated experimentally. In particular, several different modes (distinct maxima) of the particle size distribution are investigated as a function of the distance from the road. An unusual and complex evolution of these modes is discovered. In particular, it is demonstrated that some of the modes tend to shift towards smaller particle size, which has never been reported previously. Complex correlation between the modes is determined experimentally. In addition, for the first time, the total number concentration is clearly shown to go through a significant maximum at some distance from the road. This could have significant influence on the assessment of exposure to fine and ultra-fine particles in the vicinity of busy roads. [Copyright &y& Elsevier]

In this letter, the authors demonstrate that random Brownian forces can be used for effective trapping and manipulation of nanoparticles and molecules on surfaces in the presence of strong temperature modulation. Substantial (approximately two orders of magnitude) increase in the modulation of particle concentration (trapping efficiency) compared to thermophoresis in a bulk medium is predicted and explained by a periodic potential of interaction between a particle/molecule and the crystalline surface. As a result, a new nanofabrication and manipulation technique for creating optically induced complex surface structures with nanoscale resolution below tens of nanometers is proposed and developed. [ABSTRACT FROM AUTHOR]

Intravenous thrombolysis with tissue plasminogen activator (IV-tPA) is standard treatment for acute ischaemic stroke in Australia for those who meet the criteria. Its benefit, in terms of favourable outcome, is restricted to approximately 50% of patients with the remainder left severely disabled or dead. In 2012 the DRAGON score was developed and based on pre-treatment clinical parameters to predict the functional outcome post-thrombolysis in acute stroke. We aim to validate the DRAGON score in an Australian Safe Implementation of Treatment in Stroke (SITS) cohort and further refine parameters to enhance its prognostic power. We performed a retrospect review of 1561 thrombolysis patients (853 male, 708 female) from 15 Australian hospitals registered in the SITS registry between 2004 and June 2013. Relevant pre-treatment DRAGON score variables and 3 month outcome data were available for 1172 patients (649 male, 523 female). Further refinement of the score was achieved via analysis to estimate effect of independent variables on good versus miserable outcome. Logistic regression with clustering (with respect to different participating hospitals and their location) was used to derive the improved DRAGON score. Further comparison of the DRAGON scores was conducted by means of the receiver operating characteristic curve approach. As a result of the conducted logistic regression analysis, the original DRAGON score has been validated and refined (including the new weights for the considered risk factors) in the Australian context of a SITS cohort. Complete results will be presented at ANZAN Annual Scientific meeting 2014. The DRAGON score is an important pre-treatment prognostic tool to predict the functional outcome of patients undergoing thrombolysis for acute stroke and is validated in an Australian SITS cohort. [ABSTRACT FROM AUTHOR]

Abstract: In this paper we report the results of the detailed monitoring and analysis of combustion emissions from fast moving diesel trains. A new highly efficient monitoring methodology is proposed based on the measurements of the total number concentration (TNC) of combustion aerosols at a fixed point (on a bridge overpassing the railway) inside the violently mixing zone created by a fast moving train. Applicability conditions for the proposed methodology are presented, discussed and linked to the formation of the stable and uniform mixing zone. In particular, it is demonstrated that if such a mixing zone is formed, the monitoring results are highly consistent, repeatable (with typically negligible statistical errors and dispersion), stable with respect to the external atmospheric turbulence and result in an unusual pattern of the aerosol evolution with two or three distinct TNC maximums. It is also shown that the stability and uniformity of the created mixing zone (as well as the repeatability of the monitoring results) increase with increasing length of the train (with an estimated critical train length of ~10 carriages, at the speed of ~150km/h). The analysis of the obtained evolutionary dependencies of aerosol TNC suggests that the major possible mechanisms responsible for the formation of the distinct concentration maximums are condensation (the second maximum) and thermal fragmentation of solid nanoparticle aggregates (third maximum). The obtained results and the new methodology will be important for monitoring and analysis of combustion emissions from fast moving trains, and for the determination of the impact of rail networks on the atmospheric environment and human exposure to combustion emissions. [ABSTRACT FROM AUTHOR]