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OBJECTIVES: The Salivary Gland Committee of the American Academy of Otolaryngology-Head and Neck Surgery seeks to standardize terminology and technique for ultrasonograpy used in the evaluation and treatment of salivary gland disorders. METHODS: Development of expert opinion obtained through interaction with international practitioners representing multiple specialties. This committee work includes a comprehensive literature review with presentation of case examples to propose a standardized protocol for the language used in ultrasound salivary gland assessment. RESULTS: A multiple segment proposal is initiated with this focus on the submandibular gland. We provide a concise rationale for recommended descriptive language highlighted by a more extensive supplement that includes an extensive literature review with additional case examples. CONCLUSION: Recommendations are provided to improve consistency both in performing and reporting submandibular gland ultrasound.

Information Radiators (IRs) provide context-specific pieces of information in a semi-public place where a group of people can see it while working or passing-by. They can simplify information sharing “out-of-the-box”, foster awareness and socialization, create serendipity and enhance collaboration. Recent sociotechnical developments such as the establishment of permanent hybrid work settings as well as advances in the area of Human Computer Interaction (HCI) such as the emergence of Augmented Reality (AR) and Virtual Reality (VR) are likely to impact how IRs are being used – or even challenge their usefulness. In this article we discuss those developments and their possible implications for the design and use of IRs in the context of knowledge work in the next decades. We argue that IRs will probably remain an important part of future office environments providing awareness, supporting serendipity and building a situated social place for matchmaking as well as informal communication. Using new display and interaction technologies (such as AR) they might even grow in importance by enabling fluid work scenarios.

Men diagnosed with low-risk prostate cancer (PC) are increasingly electing active surveillance (AS) as their initial management strategy. While this may reduce the side effects of treatment for prostate cancer, many men on AS eventually convert to active treatment. PC is one of the most heritable cancers, and genetic factors that predispose to aggressive tumors may help distinguish men who are more likely to discontinue AS. To investigate this, we undertook a multi-institutional genome-wide association study (GWAS) of 5,222 PC patients and 1,139 other patients from replication cohorts, all of whom initially elected AS and were followed over time for the potential outcome of conversion from AS to active treatment. In the GWAS we detected 18 variants associated with conversion, 15 of which were not previously associated with PC risk. With a transcriptome-wide association study (TWAS), we found two genes associated with conversion (MAST3, p = 6.9×10-7 and GAB2, p = 2.0×10-6). Moreover, increasing values of a previously validated 269-variant genetic risk score (GRS) for PC was positively associated with conversion (e.g., comparing the highest to the two middle deciles gave a hazard ratio [HR] = 1.13; 95% Confidence Interval [CI]= 0.94-1.36); whereas, decreasing values of a 36-variant GRS for prostate-specific antigen (PSA) levels were positively associated with conversion (e.g., comparing the lowest to the two middle deciles gave a HR = 1.25; 95% CI, 1.04-1.50). These results suggest that germline genetics may help inform and individualize the decision of AS-or the intensity of monitoring on AS-versus treatment for the initial management of patients with low-risk PC.

The COVID‐19 pandemic has affected the lives of billions around the globe. Yet, our understanding of its impact on psychological distress and work productivity remains limited. Using data from two waves of the Understanding Society COVID‐19 study, a representative British survey of reactions to the COVID‐19 pandemic, comprising 5829 individuals, we find that perceived health risks related to COVID‐19 affect the productivity of working individuals negatively via increased psychological distress. Results also show that the extent of homeworking amplifies the negative relationship between psychological distress and productivity. Additionally, we find that the negative relationship between psychological distress and productivity is stronger for self‐employed individuals compared to those who are in paid employment. Psychological distress, self‐employment status and gender jointly interact in reducing productivity, such that self‐employed women experience the strongest decline in productivity. We discuss the implications of our findings in light of supporting individuals to reduce psychological distress and maintain their productivity following the COVID‐19 pandemic. [ABSTRACT FROM AUTHOR]

Objective: Rare disease Background: A mass in the parotid gland usually indicates parotid gland neoplasia. Warthin tumors or pleomorphic adenomas are common differential diagnoses. Less frequently, other differential diagnoses and sites of origin are considered. Schwannomas are rare, benign tumors in the head and neck region. Even more rarely, these tumors occur in the intraparotid course of the facial nerve. In the following, we report about 2 patients in whom a mass in the right parotid gland was found incidentally during magnetic resonance imaging (MRI). Case Reports: We reviewed data from the literature on intraparotid facial nerve schwannomas (IPFNS) and compared them with those from our cases. The focus was on data such as clinical history, clinical symptoms, electroneurography, and various imaging modalities, such as ultrasonography and MRI combined with diffusion-weighted imaging. Conclusions: It is challenging to distinguish facial nerve schwannomas from other neoplasms. Patient's history, clinical symptoms, MRI examination with diffusion-weighted imaging, and high-resolution ultrasound imaging are decisive factors for diagnosis and should be performed when IPFNS is suspected. Diagnosis and therapy for IPFNS remain challenging. A wait-and-scan approach could be an option for patients with small tumors and good facial nerve function. On the other hand, patients with advanced tumors associated with limited facial nerve function can benefit from surgical approaches or stereotactic radiosurgery. [ABSTRACT FROM AUTHOR]

The paper presents a novel offline programming (OLP) method based on programming by demonstration (PbD), which has been validated through user study. PbD is a programming method that involves physical interaction with robots, and kinesthetic teaching (KT) is a commonly used online programming method in industry. However, online programming methods consume significant robot resources, limiting the speed advantages of PbD and emphasizing the need for an offline approach. The method presented here, based on KT, uses a virtual representation instead of a physical robot, allowing independent programming regardless of the working environment. It employs haptic input devices to teach a simulated robot in augmented reality and uses automatic path planning. A benchmarking test was conducted to standardize equipment, procedures, and evaluation techniques to compare different PbD approaches. The results indicate a 47 % decrease in programming time when compared to traditional KT methods in established industrial systems. Although the accuracy is not yet at the level of industrial systems, users have shown rapid improvement, confirming the learnability of the system. User feedback on the perceived workload and the ease of use was positive. In conclusion, this method has potential for industrial use due to its learnability, reduction in robot downtime, and applicability across different robot sizes and types. [ABSTRACT FROM AUTHOR]

Background: Primary immune thrombocytopenia (pITP) in dogs presents a diagnostic challenge, and clinical markers of severity are lacking. Objectives: Identify clinicopathologic features that differentiate pITP from secondary ITP (sITP) and markers related to bleeding severity, transfusion, and survival of dogs with pITP. Animals: Ninety‐eight thrombocytopenic dogs (58 pITP and 40 sITP). Methods: Client‐owned dogs with platelet counts <50 000/μL were enrolled in a prospective, multi‐institution cohort study. History and treatment information, through a maximum of 7 days, was recorded on standard data forms. Bleeding severity was scored daily using a bleeding assessment tool (DOGiBAT). At‐admission blood samples were collected for CBC, biochemistry, C‐reactive protein concentration, and coagulation panels, and to measure platelet surface‐associated immunoglobulin G (PSAIg) and expression of platelet membrane proteins and phospholipids. Dogs with evidence of coincident disease were classified as sITP. Results: No definitive pITP diagnostic test was found. However, pITP cases were characterized by lower platelet counts, D dimer concentrations, and platelet membrane protein expression than sITP cases. Differentiation between pITP and sITP was further enhanced using logistic regression modeling combining patient sex, coagulation profile, platelet count, D dimer, and PSAIg. A second model of pITP severity indicated that low hematocrit and high BUN concentration were associated with non‐survival. Low hematocrit at admission, but not platelet count or DOGiBAT score, was associated with transfusion. Conclusions and Clinical Importance: Pending validation studies, models constructed from at‐admission clinicopathologic findings may improve differentiation of pITP from sITP and identify the most severe pITP cases at the time of presentation. [ABSTRACT FROM AUTHOR]