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Supplementary data associated with this article can be found in the online version at doi:10.1016/j.snb.2022.133001., QRsens represents a family of Quick Response (QR) sensing codes for in-situ air analysis with a customized smartphone application to simultaneously read the QR code and the colorimetric sensors. Five colorimetric sensors (temperature, relative humidity (RH), and three gas sensors (CO2, NH3 and H2S)) were designed with the aim of proposing two end-use applications for ambient analysis, i.e., enclosed spaces monitoring, and smart packaging. Both QR code and colorimetric sensing inks were deposited by standard screen printing on white paper. To ensure minimal ambient light dependence of QRsens during the real-time analysis, the smartphone application was programmed for an effective colour correction procedure based on black and white references for three standard illumination temperatures (3000, 4000 and 5000 K). Depending on the type of sensor being analysed, this integration achieved a reduction of ~71 – 87% of QRsens’s dependence on the light temperature. After the illumination colour correction, colorimetric gas sensors exhibited a detection range of 0.7–4.1%, 0.7–7.5 ppm, and 0.13–0.7 ppm for CO2, NH3 and H2S, respectively. In summary, the study presents an affordable built-in multi-sensing platform in the form of QRsens for in-situ monitoring with potential in different types of ambient air analysis applications., Spanish MCIN/AEI/10.13039/ 501100011033/ (Projects PID2019–103938RB-I00, ECQ2018–004937- P and grant IJC2020–043307-I), Junta de Andalucía (Projects B- FQM-243-UGR18, P18-RT-2961), European Regional Development Funds (ERDF), European Union NextGenerationEU/PRTR

Supplementary data to this article can be found online at https://doi. org/10.1016/j.bios.2023.115268, The COVID-19 pandemic has highlighted the need for innovative approaches to its diagnosis. Here we present CoVradar, a novel and simple colorimetric method that combines nucleic acid analysis with dynamic chemical labeling (DCL) technology and the Spin-Tube device to detect SARS-CoV-2 RNA in saliva samples. The assay includes a fragmentation step to increase the number of RNA templates for analysis, using abasic peptide nucleic acid probes (DGL probes) immobilized to nylon membranes in a specific dot pattern to capture RNA fragments. Duplexes are formed by labeling complementary RNA fragments with biotinylated SMART bases, which act as templates for DCL. Signals are generated by recognizing biotin with streptavidin alkaline phosphatase and incubating with a chromogenic substrate to produce a blue precipitate. CoVradar results are analysed by CoVreader, a smartphone-based image processing system that can display and interpret the blotch pattern. CoVradar and CoVreader provide a unique molecular assay capable of detecting SARS-CoV-2 viral RNA without the need for extraction, preamplification, or pre-labeling steps, offering advantages in terms of time (similar to 3 h/test), cost (similar to epsilon 1/test manufacturing cost) and simplicity (does not require large equipment). This solution is also promising for developing assays for other infectious diseases., FEDER/Junta de Andalucia-Consejeria de Economia y Conocimiento CV20-77741, A-FQM-760-UGR20, PID 2019-110987RB-I00, PID 2019-103938RB-I00, Spanish MCIN/AEI P18-RT-2961, P18-TP-4160, FEDER/Junta de Andalucia-Consejeria de Salud y Familias PIP-0232-2021, European Commission, MCIN/AEI PTQ 2020-011388, IJC 2020-043307-I, European Union NextGenerationEU/PRTR PTQ 2020-011388, IJC 2020-043307-I

This article presents a smart bandage with wireless strain and temperature sensors and a batteryless near-field communication (NFC) tag. Both sensors are based on conductive poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) polymer. The highly sensitive strain sensor consists of a microfluidic channel filled with PEDOT:PSS in Polydimethylsiloxane (PDMS) substrate. The strain sensor shows 3 order (~1250) increase in the resistance for 10% strain and considerably high gauge factor (GF) of ~12 500. The sensor was tested for ~30% strain, which is more than typical stretching of human skin or body parts such as chest expansion during respiration. The strain sensor was also tested for different bending and the electrical resolution was ~150% per degree of free bending and ~12k% per percentage of stretching. The resistive temperature sensor, fabricated on a Polyvinyl Chloride (PVC) substrate, showed a ~60% decrease in resistance when the temperature changed from 25 °C to 85 °C and a sensitivity of ~1% per °C. As a proof of concept, the sensors and NFC tag were integrated on wound dressing to obtain wearable systems with smart bandage form factor. The sensors can be operated and read from distance of 25 mm with a user-friendly smartphone application developed for powering the system as well as real-time acquisition of sensors data. Finally, we demonstrate the potential use of smart bandage in healthcare applications such as assessment of wound status or respiratory diseases, such as asthma and COVID-19, where monitoring via wearable strain (e.g., respiratory volume) and temperature sensors is critical.

This paper presents a smart sensor patch with flexible strain sensor and a printed temperature sensor integrated with a Near Field Communication (NFC) tag to detect strain or temperature in a semi-quantitative way. The strain sensor is fabricated using conductive polymer poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) in a polymer Polydimethylsiloxane microchannel. The temperature sensor is fabricated by printing silver electrodes and PEDOT:PSS on a flexible polyvinyl chloride (PVC) substrate. A customdeveloped battery-less NFC tag with an LED indicator is used to visually detect the strain or temperature by modulating the LED light intensity. The LED shows maximum brightness for relaxed or no strain condition, and also in the case of maximum temperature. In contrast, the LED is virtually off for the maximum strain condition and for room temperature. Both these could be related to food spoilage. Swollen food packages can be detected with the strain sensor, serving as beacons of microbial contamination. Temperature deviations can result in the growth or survival of food-spoilage bacteria. Based on this, the potential application of the sensor system for smart food packaging is presented.

In this work, a compact affordable and portable spectral imaging system is presented. The system is intended to be employed in general applications, such as material classification or determination of the concentration of chemical species together with colorimetric sensors. The imaging device is reduced to a small digital color detector with an active area of 3 × 2mm2. This device provides a quantification of the incident emission in the form of four digital words corresponding to its averaged components blue, green, red, and near infrared. In this way, the size of the image is reduced to one pixel. The wavelength selection is carried out by means of a LED array disposed surrounding the color detector. The LEDs are selected to cover the wavelength range from 360 to 890 nm. A sequential measurement protocol is followed, and the generated data is transmitted to an external portable device via a Bluetooth link where a classification protocol is implemented in a custom-developed Android™ application. The presented system has been applied in three different scenarios involving material classification, meat freshness monitoring, and chemical analysis. The analysis of the data using principal components shows that it is possible to find a set of wavelengths where the classification of the samples is optimal., This work was supported by project CTQ2016-78754-C2-1-R from the Spanish Ministry of Economy and Competitiveness.

Thermal sintering has traditionally been the most popular sintering method to enhance conductivity after the printing process in the manufacturing of printed electronics. Nevertheless, in recent years, there has been a growing interest in electrical sintering as an alternative method to overcome some of the limitations of thermal curing. This paper makes a comparative study of both sintering methods in terms of surface morphology, electrical dc conductance, and radiofrequency performance for different applied voltage waveforms. To this end, microstrip transmission lines have been inkjet-printed using nanoparticle-based silver ink on flexible polyimide substrate. The traces have been tested under different sintering conditions, achieving electrical sintering resistivity values only 2.3 times higher than that of bulk silver. This implies a 62% reduction in comparison with the best resistivity value achieved using thermal sintering in our samples. The main novelty of this contribution lies in the analysis of RF behavior as a function of electrical sintering conditions. Lower resistivities have been achieved with slower voltage ramps or allowing higher density current during sintering. It has also been proved that electrically sintered lines have similar RF performance than high-temperature thermally sintered lines in terms of insertion losses, regardless of their very different surface topology. Therefore, we can take advantage of the benefits that electrical sintering offers over thermal sintering regarding significant shorter sintering times maintaining suitable RF performance., This work was supported in part by the Spanish Ministry of Economics and Competitiveness under Grant CTQ2016-78754-C2-1-R.

Herein, a novel tactile sensing device (SensAct) with a soft touch/pressure sensor seamlessly integrated on a flexible actuator is presented. The squishy touch sensor is developed with custom-made graphite paste on a tiny permanent magnet, encapsulated in Sil-Poxy, and the actuator (15 μ-thick coil) is fabricated on polyimide by Lithographie Galvanoformung Abformung (LIGA) micromolding method. The actuator can operate in two modes (expansion and contraction/squeeze) and two states (vibration and nonvibration). The sensor was tested with up to 12 N applied forces and exhibited ≈70% average relative resistance variation (ΔR/Ro), ≈0.346 kPa−1 sensitivity, and ≈49 ms response time with excellent repeatability (≈12.7% coefficient of variation) at 5 N. During simultaneous sensing and actuation, the modulation of coil current, due to ΔR/Ro (≈14% at 2 N force) in the sensor, allows the close loop control (ΔI/Io ≈385%) of expansion/contraction (≈69.8 μm expansion in nonvibration state and ≈111.5 μm peak-to-peak in the vibration state). Finally, the soft sensor is embedded in the 3D-printed fingertip of a robotic hand to demonstrate its use for pressure mapping along with remote vibrotactile stimulation using SensAct device. The self-controllable actuation of SensAct could provide eSkin the ability to tune stiffness and the vibration states could be utilized for controlled haptic feedback.

Several studies have shown that the determination of pH in sweat, which is one of the most accessible body fluids, can be an indicator of health and wellness, and even be used for potential disease diagnosis. On that basis, we present herein a wearable wristband for continuous and wireless monitoring of sweat pH with potential applications in the field of personal health assessment. The developed wristband consists of two main parts: a microfluidic cloth analytical device (μCAD) to collect continuously the sweat from skin with a color-based pH sensing area; and a readout and processing module with a digital color sensor to obtain the pH of sweat from the color changes in the μCAD. In addition, the readout module includes a low-power Bluetooth interface to transmit the measurements in real-time to a custom-designed smartphone application. To allow continuous operation, an absorbent pad was included in the design to retire and store thsweat from the sensing area through a passive pump path. It was found that the Hue parameter (H) in the HSV color space can be related to the sweat pH and fitted to a Boltzmann equation (R2 = 0.997). The range of use of the wristband device goes from 6 to 8, which includes the pH range of sweat, with a precision at different pH values from 3.6 to 6.0 %. Considering the typical human sweat rate, the absorbent pad allows continuous operation up to more than 1000 min.

In this work, we present a ballistocardiographic (BCG) system for the determination of heart and breath rates and activity of a user lying in bed. Our primary goal was to simplify the analog and digital processing usually required in these kinds of systems while retaining high performance. A novel sensing approach is proposed consisting of a white LED facing a digital light detector. This detector provides precise measurements of the variations of the light intensity of the incident light due to the vibrations of the bed produced by the subject’s breathing, heartbeat, or activity. Four small springs, acting as a bandpass filter, connect the boards where the LED and the detector are mounted. Owing to the mechanical bandpass filtering caused by the compressed springs, the proposed system generates a BCG signal that reflects the main frequencies of the heartbeat, breathing, and movement of the lying subject. Without requiring any analog signal processing, this device continuously transmits the measurements to a microcontroller through a twowire communication protocol, where they are processed to provide an estimation of the parameters of interest in configurable time intervals. The final information of interest is wirelessly sent to the user’s smartphone by means of a Bluetooth connection. For evaluation purposes, the proposed system has been compared with typical BCG systems showing excellent performance for different subject positions. Moreover, applied postprocessing methods have shown good behavior for information separation from a single-channel signal. Therefore, the determination of the heart rate, breathing rate, and activity of the patient is achieved through a highly simplified signal processing without any need for analog signal conditioning., Junta de Andalucia European Commission PYC20-RE-040 UGR MCIN/AEI/10.13039/501100011033/with PID2019-103938RB-I00, European Commission

Integration of sensors with antennas is becoming popular for compact high-performance wireless sensing systems. In this direction, here we present a silver electrodes and Poly(3,4-ethylenedioxythiophene:polystyrene (PEDOT:PSS) based printed temperature sensor on a flexible PVC substrate. The temperature sensor was characterised using a digital multimeter for a temperature range from 25¤C to 90□C. The sensor showed a 70% change in resistance for the tested temperature range. Further, the sensing part was integrated with a Near Field Communication (NFC) tag with the data obtained semi-quantitatively by means of the intensity of an Light Emittign Diode (LED) connected with the antenna system. In this case, the antenna works as an energy harvester to power an LED indicator connected in series to the resistive temperature sensor. The intensity of the LED, which varies with the increase of temperature, was measured using a lux-meter mobile application. The intensity at 70□C was ~42 lux whereas it decreased down to ~14 lux at room temperature (~25□C). The presented system showed potential use as a smart label in applications requiring temperature monitoring.

This paper presents a miniaturized potentiostat readout circuit patch developed for electrochemical or biosensors. The presented patch has been fabricated on a flexible polyimide substrate using off-the-shelf electronics. In contrast to the traditional bulky equipment for electrochemical analysis, the presented patch is conformable and portable. As a proof of concept, the system has been used for pH measurements in buffer solution (6- 8 pH values) with a printed thick film potentiometric pH sensor having platinum counter electrode. The obtained results are in line with a commercially available potentiostat that has been used for benchmarking.

In this work we present a polymer-based flexible strain sensor integrated with an NFC tag to detect strain by means of a visual LED indicator. The sensor was fabricated using conductive polymer poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) as an active material inside a flexible and transparent polymer Polydimethylsiloxane (PDMS) microchannel. The strain sensor changes its resistance at different bending conditions, showing up to three order increase in resistance for $\sim 100$ bending. A custom-developed passive NFC tag with an LED connected in series to the strain sensor is powered from an NFC reader to detect strain in a semi-quantitative way. The light intensity of the LED indicator is modulated according to the strain level, showing maximum brightness $(\sim 67$ lux) for relaxed or no strain condition, and being almost OFF $(\sim 8$ lux) for the maximum strain condition. The potential application of the NFC-based strain sensor system in food package for spoilage detection is also presented.

Disposable and flexible sensors are needed in biomedical and healthcare applications because of hygiene requirements. At the same time, they should provide an affordable solution for point-of-care (POC) testing and large-scale deployment. In this view, herein we report flexible polyimide-based disposable sensor patch for the detection of a-amylase in blood serum. The concentration of a-amylase in blood serum is a potential indicator of health issues such as pancreatitis and pancreatic cancer and an affordable solution to detect its concentration could benefit many. Here, the detection is based on thermal Marangoni circulation inside a microfluidic droplet of starch-FeSO 4 salt solution, which detects the a-amylase concentration upon addition of blood serum. It was observed that the temperature difference between the droplet substrate and ambient sets a thermal Marangoni and natural convections motion inside the droplet. The performance of the microdropletbased sensor was best at temperature difference (~18–20°C). The sensor is capable of detecting 20-110 units/liter concentration of α-amylase with ~80% change in the electrical resistance across the microdroplet (at ~40°C substrate temperature), and with a sensitivity of 0.88% (units/liter) -1 . The response of the sensor was also compared with pathological laboratory results and both were found to be in agreement. The presented sensor has the potential to be used as a POC device for detecting α-amylase in real-time.

Electronic skin or eSkin is critical to enhance the interactive capabilities of robots through physical contact. The current approaches to develop this capability involve using multiple sensors distributed on robot’s body. Energy requirement of such eSkin is currently met through batteries, which is not ideal as it may reduce the operational time and requires frequent charging. In this work, we present an eSkin consisting of distributed energy autonomous proximity sensors. The eSkin contains an array of miniaturized solar cells to generate energy needed for infrared LEDs based proximity sensors. As a proof of concept, the eSkin has been integrated in an industrial robot arm UR5 and proximity sensing has been shown to enable safe Human-Robot Interaction (HRI).

Concentration of α-amylase in human serum is a key indicator of various pancreatic ailments and an affordable point-of-care detection of this biomarker can benefit millions suffering from these diseases. In view of this situation, we report the development of a flexible patch-sensor, which simply requires a microdroplet of aqueous starch-FeSO4 solution to detect α-amylase in serum. The detection is achieved through the generation of mixing vortices (~12 rpm) inside the droplet with the help of an imposed thermal gradient. Such vortices due to Marangoni and natural convections are found to be strongest at an optimal temperature difference of ~18 °C - 23 °C across the droplet which in turn facilitate mixing and promote the specific starch-amylase enzymatic reaction. Subsequently, the large (~80%) variation in the electrical resistance across the droplet is correlated to detect the level of the α-amylase in the analyte. Importantly, the sensor can detect even in the limits of 15-110 units/liter. Further, the sensitivity of flexible sensors is ~8.6% higher than the non-flexible one. Interestingly, the sensitivity of the proposed sensor has been nearly three-times than the previously reported optical ones. The results of patch-sensor match very closely with the standard path-lab tests while detecting unknown level of amylase in serum. The prototype has shown significant potential to translate into an affordable device for the real-time detection and easy prognosis of pancreatic disorders.

This paper presents a polymer strain sensor integrated with\ud an NFC tag to detect strain semi-quantitatively. The strain\ud sensor is fabricated using flexible and transparent polymer\ud Polydimethylsiloxane (PDMS) microchannel having\ud conductive polymer poly (3,4-ethylenedioxythiophene)\ud polystyrene sulfonate (PEDOT:PSS) as an active material.\ud The sensor was tested with different bending conditions\ud and it was found that the resistance increases with higher\ud bending. A maximum of 3 order change in resistance was\ud observed for ~100 bending. The sensor was finally tested\ud using a custom-developed passive NFC tag having an LED\ud connected in series with the strain sensor and powered from\ud the reader via the NFC antenna in the tag.

This paper presents poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate polymer microchannel (diameter ≈175 µm) based stretchable strain sensor developed inside polydimethylsiloxane substrate. The microchannel diameter changes when subjected to various strains, leading to change in the resistance of strain sensor. The sensor exhibits about three order (ΔR /R 0 ≈ 1200) increase in the resistance (R ) for 10% applied strain (ΔL /L , L = length of the sensor). This leads to a gauge factor (GF Δ (ΔR /R 0)/(ΔL /L ) of ≈12 000, which is about ≈400 times higher than most of the reported polymer‐based strain sensors. The sensor is evaluated up to a maximum strain of 30%, which is the standard strain limit associated with human body parts such as fingers and wrists. The sensor exhibits a considerably good average degree of hysteresis (

This work was supported in part by the Spanish Research and Development National Program under Project TIN2016-75097P and Project RTI2018-102002-A-I00, in part by "Junta de Andalucia" under Project B-TIC-402-UGR18 and Project P18.RT.4830, and in part by the Predoctoral Grant FPU18/01965., In this brief, we present a low-loss mechanically reconfigurable phase shifter implemented in gap-waveguide technology for mm-wave frequencies. The proposed design gives a practical implementation of tuning elements inside the waveguide providing alternatives to the use of the E-plane split waveguide at high frequencies in order to avoid leakage losses. The depicted phase shifter design is based on a H-plane split waveguide. The phase shift is controlled by means of a tuning screw, which exerts pressure on a flexible metallic strip inserted inside the waveguide. The flexible strip bends with different curvature radii and determines the phase shift at the output port. Cost-effective manufacturing and simple implementation of the flexible metallic strip are achieved by means of the gap-waveguide design. A prototype has been manufactured for validation purposes. Good impedance matching is achieved from 64 GHz to 75 GHz providing a 15.8% impedance bandwidth. The results show a maximum phase shift of 250° with a maximum and mean insertion loss (IL) of 3 dB and 1.7 dB, respectively., Spanish Research and Development National Program TIN2016-75097P RTI2018-102002-A-I00, Junta de Andalucia B-TIC-402-UGR18 P18.RT.4830, FPU18/01965

In this paper we present the design, fabrication and characterization of electro-textile inductor and capacitor patterns on denim fabric as a basis for the development of wearable e-textiles. Planar coil inductors have been harnessed as antenna structures for the development of near field communication tags with temperature sensing capability, while interdigitated electrode capacitors have been used as humidity sensors for wearable applications. The effect of bending in the electrical performance of such structures was evaluated, showing variations below 5% in both inductance and capacitance values for bending angles in the range of interest; that is, those fitting to human limbs. In the case of the fabricated near field communication tags, a shift in the resonance frequency below 1.7% was found, meaning that the e-textile tag would still be readable by a near field communication-enabled smartphone. In respect of the capacitive humidity sensor, we obtained a minimum capacitance variation of 40% for a relative humidity range from 10% to 90%. Measured thermal shift was below 5% in the range from 10 to 40℃. When compared with the 4% variation due to bending, it can be concluded that this capacitive structure can be harnessed as a humidity sensor even under bending strain conditions and moderate temperature variations. The development and characterization of such structures on denim fabrics, which is one of the most popular fabrics for everyday clothing, combined with the additional advantage of affordable and easy fabrication methodologies, means a further step towards the next generation of smart e-textile products.

The authors would like to acknowledge to the staff of the Hospital Universitario Clínico San Cecilio, Granada, Spain, for their support and use of the facilities. We also thank the reviewers for their useful and constructive comments and suggestions which have improved this paper., Safe quality control of radiotherapy treatments lies in reliable dosimetric sensors. Currently, ionization chambers and solid-state diodes along with electrometers as readout systems are accomplishing this task. In this work, we present a well-known and low-cost semiconductor sensor, the light-dependent resistor (LDR), as an alternative to the existing sensing devices for dosimetry. To demonstrate this, a complete characterization of the response to radiation of commercial LDRs has been conducted in terms of sensitivity, reproducibility and thermal correction under different bias voltages. Irradiation sessions have been applied under the common conditions in radiotherapy treatments using a hospital linear accelerator. Moreover, the same electrometer used for the ionization chamber has also been successfully used for LDRs. In comparison with the sensitivity achieved for the ionization chamber (0.2 nC/cGy at 400 V bias voltage), higher sensitivities have been measured for the proposed LDRs, ranging from 0.24 to 1.04 nC/cGy at bias voltages from 30 to 150 V, with a reproducibility uncertainty among samples of around 10%. In addition, LDR temperature dependence has been properly modeled using the simple thermistor model so that an easy thermal drift correction of dose measurements can be applied. Therefore, experimental results show that LDRs can be a reliable alternative to dosimetric sensors with the advantages of low size, affordable cost and the fact that it could be adopted with minimal changes in routine dosimetry quality control since the same readout system is fully compatible., Junta de Andalucía B-TIC-468-UGR18 PI-0505-2017, European Union (EU)

A portable device based on a colorimetric sensor to determine the atmospheric level of CO2 gas is presented in this work. The system is based on a low-cost, low-power System on a Chip (SoC) microcontroller with integrated Wi-Fi. A user-friendly application was developed to monitor and log the CO2 measurements when the system is connected to a Wi-Fi network. The sensing membrane is directly deposited on the surface of the colour detector, thus reducing the complexity of the system. This sensing membrane is formed by a pH indicator α-naphtholphthalein, tetramethylammonium hydroxide pentahydrate, 1-ethyl-3-methylimidazolium tetrafluoroborate, Tween 20 and hydroxypropyl methylcellulose as the hydrophilic polymer. The system has been fully characterized, obtaining response and recovery times of 1.3 and 2.5 s, respectively, a limit of detection of 51 ppm, and an average resolution of 6.3 ppm. This portable device was applied for the in-situ determination of CO2 gas in the atmosphere inside classrooms in several secondary schools. The measurements were taken during complete workdays and the results were statistically compared with the same measurements taken using a commercially available non-dispersive infra-red (NDIR) device. No significant statistical differences were found between the results obtained using both devices. A complete statistical treatment of the measurements made with the proposed portable device was carried out. The obtained results show that the concentration of CO2 gas in some schools was higher than the desired concentration, with regard to influencing the student's health, safety, productivity and comfort. This demonstrates the need to control this parameter to ensure appropriate indoor environmental quality (IEQ).

In this work we present a novel technique to estimate the resonance frequency of LC chipless tags (inductor-capacitor parallel circuit) with improved sensitivity and linearity. The developed reader measures the power consumption of a Colpitts oscillator during a frequency sweep. The readout circuit consists of a Colpitts oscillator with a coil antenna, varactor diodes to change the oscillator frequency, analog circuitry to measure the power consumption and a microcontroller to control the whole system and send the data to a PC via USB. When an LC tag is inductively coupled to the oscillator, without contact, a maximum power peak is found. As shown by an experimental calibration using an LC tag made on FR4 substrate, the frequency of this maximum is related to the resonance frequency. Both parameters, power consumption and resonance frequency, present an excellent linear dependence with a high correlation factor (R 2 = 0.995). Finally, a screen-printed LC tag has been fabricated and used as relative humidity sensor achieving a sensitivity of (−2.41 ± 0.21) kHz/% with an R 2 of 0.946.

Electronic skin (eSkin) with various types of sensors over large conformable substrates has received considerable interest in robotics. The continuous operation of large number of sensors and the readout electronics make it challenging to meet the energy requirements of eSkin. In this article, we present the first energy generating eSkin with intrinsic tactile sensing without any touch sensor. The eSkin comprises a distributed array of miniaturized solar cells and infrared light emitting diodes (IRLEDs) on soft elastomeric substrate. By innovatively reading the variations in the energy output of the solar cells and IRLEDs, the eSkin could sense multiple parameters (proximity, object location, edge detection, etc.). As a proof of concept, the eSkin has been attached to a 3-D-printed hand. With an energy surplus of 383.6 mW from the palm area alone, the eSkin could generate more than 100 W if present over the whole body (area ∼1.5 m2). Further, with an industrial robot arm, the presented eSkin is shown to enable safe human−robot interaction. The novel paradigm presented in this article for the development of a flexible eSkin extends the application of solar cell from energy generation alone to simultaneously acting as touch sensors.

Most robotic/prosthetic hands lack the ability to harvest energy, and as a result they rely on the batteries to provide the required energy for their operation. Recently solar cells have been explored to meet the energy requirements. However, most solar cells are brittle, and their chances of getting damaged during robotic operation are high. The work presented in this paper addresses this challenge through a transparent 3D printed package covering three photovoltaic cells. The package protects the cells from impact and prevents dust accumulation while ensuring minimal loss of light reaching the cells. The effect of the protective 3D printed cover on the performance of photovoltaic panel have been evaluated. This solar cell package is integrate on a 3D printed robotic hand to harvest energy from the environmental illumination and utilizes it to power the small peripheral electronic and sensing components on the hand.

A novel approach of a gas pressure infiltration technique is presented for the synthesis of Co-Continuous Ceramic Composite (C4). SiC foams of varying pore sizes were infiltrated with aluminium AA5083. Optical examination revealed that the SiC foams contained open cells with a network of triangular voids. The number of pores-per-inch (PPI) in the foams was found to depend on the strut thickness and pore diameter. The compressive strengths of two foam configurations, 10 and 20 PPI, were estimated to lie between 1–2 MPa. After infiltration, the compressive yield strength of the resulting C4 was observed to increase to 126 MPa and 120 MPa, respectively, for the 10 and 20 PPI C4. Additionally, the infiltration of ceramic foam with the AA5083 alloy resulted in an increase in strength of 58–100 times when compared with plain ceramic foam. The failure modes of the composites in compression were analyzed by crack propagation and determining the type of failure. The study revealed that shear failure and vertical splitting were the predominant mechanisms of compression failure, and that the fabricated C4 is advantageous in mechanical properties compared to the plain ceramic foam. This study, therefore, suggests the use of C4 composites in armour applications.

The development of a contactless readout system for High Frequency (HF) tags and its application to relative humidity monitoring is presented. The system consists of a Colpitts oscillator circuit whose frequency response is determined by a built-in logic counter of a microcontroller unit. The novel readout strategy is based on the frequency response change due to the inductive coupling between the coil of the Colpitts oscillator and the load impedance of a parallel LC resonator tag, as a result of the variation of the humidity sensing capacitor. The frequency is monitored with a low cost microcontroller, resulting in a simple readout circuit. This passive LC tag has been directly screen-printed on a humidity-sensitive flexible substrate. The readout circuit experimental uncertainty as frequency meter was 4 kHz in the HF band. A linear temperature drift of (-1.52 ± 0.17) kHz/⁰C was obtained, which can be used to apply thermal compensation if required. The readout system has been validated as a proof of concept for humidity measurement, obtaining a significant change of about 260 kHz in the resonance frequency of the Colpitts oscillator when relative humidity varies from 10% to 90%, with a maximum uncertainty of ±3% (±2 SD). Therefore, the proposed readout system stands as a compact, low-cost, contactless solution for chipless HF tags that avoids the use of bulky and costly equipment for the analog reading of wireless passive LC sensors., This work was supported by project CTQ2016-78754-C2-1-R from the Spanish Ministry of Economics and Competitivity. P. Escobedo wants to thank the Spanish Ministry of Education, Culture and Sport (MECD) for a pre-doctoral grant (FPU13/05032).

This communication presents the design of a two-port electronically tunable phase shifter at K band. The phase shifter consists of a 3 dB hybrid coupler loaded with reflective phase-controllable circuits. The reflective circuits are formed by varactors and non-sequential impedance transformers which increase the operational bandwidth and the provided phase shift. The final phase shifter design is formed by two loaded-coupler stages of phase shifting to guarantee a complete phase turn. An 18 GHz phase shifter design with dynamic range of 600 degrees of phase shift is depicted in this document. The prototype is manufactured and validated through measurements showing good agreement with the simulation results., This work has been partially supported by the TIN2016-75097-P, RTI2018-102002-A-I00, and EQC2018- 004988-P projects of the Spanish National Program of Research, Development, and Innovation and project B-TIC-402-UGR18 of Junta de Andalucía

Leishmaniasis and Chagas disease are endemic in many countries, and re-emerging in the developed countries. A rapid and accurate diagnosis is important for early treatment for reducing the duration of infection as well as for preventing further potential health complications. In this work, we have developed a novel colorimetric molecular assay that integrates nucleic acid analysis by dynamic chemistry (ChemNAT) with reverse dot-blot hybridization in an array format for a rapid and easy discrimination of Leishmania major and Trypanosoma cruzi. The assay consists of a singleplex PCR step that amplifies a highly homologous DNA sequence which encodes for the RNA component of the large ribosome subunit. The amplicons of the two different parasites differ between them by single nucleotide variations, known as “Single Nucleotide Fingerprint” (SNF) markers. The SNF markers can be easily identified by naked eye using a novel micro Spin-Tube device "Spin-Tube", as each of them creates a specific spot pattern. Moreover, the direct use of ribosomal RNA without requiring the PCR pre-amplification step is also feasible, further increasing the simplicity of the assay. The molecular assay delivers sensitivity capable of identifying up to 8.7 copies per μL with single mismatch specificity. The Spin-Tube thus represents an innovative solution providing benefits in terms of time, cost, and simplicity, all of which are crucial for the diagnosis of infectious disease in developing countries., This research work has received funding from Junta de Andalucía, Consejería de Economía e Innovación (project number 2012-BIO1778), the Spanish Ministerio de Economía y Competitividad (Grants CTQ2012-34778, BIO2016-80519-R, FPI Grant BES-2013- 063020). This research was partially supported by the 7th European Community Framework Program (FP7-PEOPLE-2012-CIG-Project Number 322276).

In this paper, we present a passive tag for the determination of gaseous oxygen in intelligent packaging (IP). The power supply for this tag is obtained from thermoelectric energy harvesting taking advantage of the temperature difference between a cooled package and the human body. For this purpose, a compact Peltier module is attached to the surface of the package. This device is able to generate 1.2 mW when a temperature difference of 25 °C is applied between its surfaces. A dc-to-dc boost converter is included to generate an output voltage of 3.3 V and an output current of 225 μA from the harvested energy by the Peltier cell, which are used to supply the measurement circuitry. A luminescent membrane sensitive to oxygen is used as a gas detector in the package. The generated signal is compared to a reference value to evaluate if the oxygen concentration inside the package falls below or above a predetermined value. This is shown by turning on a green or a red LED, respectively. The proposed system presents a resolution of 0.02% of the predicted oxygen concentration in the range of interest (0%- 5%) and a limit of detection (LOD) of 0.007%, which makes the instrument appropriate to be used in IP and active packaging (AP) technology.

Here, we present a technique for the determination of the gaseous oxygen concentration 2 inside packed food. It is based on the use of a luminescent membrane sensitive to O2 that is optically excited and read by a smartphone. The flash of the smartphone along with an optical filter is used as the light source for the optical stimulation of the membrane. The luminescence generated, which is quenched by the surrounding gaseous oxygen, is registered by the rear camera of the same device. The response parameter is defined by combining the registered intensities at two different wavelength ranges corresponding to the emission and the absorption peaks of the sensitive membrane. Thanks to this novel response parameter, the sensitivity is increased and, more importantly, the thermal dependence of the membrane is significantly reduced. This approach allows the use of a luminescent O2-sensitive membrane for intelligent packaging with no need of any associated electronics for its excitation and reading. This means that an oxygen sensor is developed, where a luminescent compound acts as an indicator, therefore combining the advantages of both schemes, that is, the simplicity and reduced cost of indicators with the high sensitivity and accuracy of selective sensors., This work was supported by the Spanish Ministry of Economics and Competivity through the Project CTQ2016-78754-C2-1-R. The work P. Escobedo Araque was supported by the Spanish Ministry of Education, Culture and Sport under Grant FPU13/05032. The work of I. Pérez de Vargas-Sansalvador was supported in part by the European Union’s Horizon 2020 Research and Innovation Program (Multisens) under Grant 706303, in part by the Talentia Postdoc Program launched by the Andalusian Knowledge Agency, in part by the European Union’s Seventh Framework Program, in part by the Marie Skłodowska-Curie actions (COFUND) under Grant 267226, and in part by the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucía.

The authors acknowledge the Servicio de Radiofísica (Radio-physics Service) of the Hospital Universitario San Cecilio (Granada, Spain) for permitting us to use their installations. This work was funded by the Spanish Government under project FPA2015-67694-P (Spanish Ministry of Economy, Industry and Competitiveness) and a R&D predoctoral grant (FPU13/05032, Spanish Ministry of Education, Culture and Sport). This project is partially supported by European Regional Development Funds (ERDF)., In this work we describe and evaluate a dosimetric system based on an NFC (Near Field Communication) tag and a smartphone that uses commercial MOSFETs as radiation sensors. The tag is designed with commercial integrated circuits and the smartphone is the power source of the tag configured as a readout unit, user interface and storage unit. The NFC tag is supplied wirelessly by the smartphone via NFC, using a home-made structure to align the tag coil and smartphone coil in order to achieve a good inductive coupling. In this case, the commercial DMOS transistor ZVP3306 is used as dosimeter in unbiased mode, connected to the tag before and after each irradiation session to perform the sensor reading. An evaluation of the dosimetric system has been carried out irradiating three transistors with photon beam of 6 MV up to 20 Gy. The average sensitivity found is (4.75 ± 0.15) mV/Gy, which is in good agreement with the results found with our previously developed dosimetric system. Therefore, this miniaturised dosimetric system can be considered as a promising and low cost electronic architecture to be used for dosimetry control in radio-therapy treatments., Servicio de Radiofísica (Radio-physics Service) of the Hospital Universitario San Cecilio (Granada, Spain), Spanish Government under project FPA2015-67694-P (Spanish Ministry of Economy, Industry and Competitiveness) and a R&D predoctoral grant (FPU13/05032, Spanish Ministry of Education, Culture and Sport), European Regional Development Funds (ERDF)

In this work we present a full-passive flexible multigas sensing tag for the determination of oxygen, carbon dioxide, ammonia, and relative humidity readable by a smartphone. This tag is based on near field communication (NFC) technology for energy harvesting and data transmission to a smartphone. The gas sensors show an optic response that is read through high-resolution digital color detectors. A white LED is used as the common optical excitation source for all the sensors. Only a reduced electronics with very low power consumption is required for the reading of the optical responses and data transmission to a remote user. An application for the Android operating system has been developed for the power supplying and data reception from the tag. The responses of the sensors have been calibrated and fitted to simple functions, allowing a fast prediction of the gases concentration. Cross-sensitivity has also been evaluated, finding that in most of the cases it is negligible or easily correctable using the rest of the readings. The election of the target gases has been due to their importance in the monitoring of modified atmosphere packaging. The resolutions and limits of detection measured are suitable for such kinds of applications.

Omega (ω) phase is formed in alpha (α) zirconium during dynamic loading and can be retained in the recovered material. The pathway for the α to ω change (or the reverse transformation) is not well understood. Zirconium was shock-loaded and the resulting two-phase microstructure was examined. Electron backscatter diffraction (EBSD) was used to characterize the orientation relationships and habit planes between phases to understand the pathways between α and ω phases and compare to Molecular Dynamics (MD) simulations. Based on key microstructural features, a significant amount of α phase appears to have originated from the reverse transformation from ω-Zr on unloading. Results of microstructural analysis will be discussed, along with implications toward phase transformation pathways.

A versatile, compact and low-cost analytical platform has been designed, tested and validated to be used in the point-of-care settings. This passive measurement system is powered and complemented by a standard smart- phone including a programmed application for measurement configuration and data processing as well as wireless results sharing. Electrochemical and electrochemiluminescence analytical techniques can be configured and realized by this platform that employs standard screen-printed electrodes for the sample managing and off- the-shelf electronic components. The power, electrical and optical signal processing have been studied in depth. The system can harvest energy up to 22.5 mW, set up a voltage in the range of±1.15 V, and measure potentials in a range of 600 mV with an uncertainty of 1 mV, and current from 2 μA to 0.75 mA with a resolution of 1.1 μA. Moreover, standard tests have been performed to the platform consisting of amperometric, potentiometric, cyclic voltammetry and electrochemiluminescent analytical techniques, showing excellent agreement with a reference instrument. Finally, our design has also been applied to glucose, pH and H2O2 determinations, providing the full analytical parameters which are in very good agreement with the reference instrument results. Ranges (0.065–0.75 M, 0.62–100mM and 3–9 pH units for glucose, H2O2 and pH, respectively) and limits of detection (0.024 M and 0.03mM for glucose and H2O2, respectively) make this low-cost platform (< US$8) suitable for analytical applications.

This work presents the design, fabrication, and characterization of a passive printed radiofrequency identification tag in the ultra-high-frequency band with multiple optical sensing capabilities. This tag includes five photodiodes to cover a wide spectral range from near-infrared to visible and ultraviolet spectral regions. The tag antenna and circuit connections have been screen-printed on a flexible polymeric substrate. An ultra-low-power microcontroller-based switch has been included to measure the five magnitudes issuing from the optical sensors, providing a spectral fingerprint of the incident electromagnetic radiation from ultraviolet to infrared, without requiring energy from a battery. The normalization procedure has been designed applying illuminants, and the entire system was tested by measuring cards from a colour chart and sensing fruit ripening.

This work presents the design, fabrication and characterization of a fully passive radiofrequency identification tag in the ultra-high frequency band with multiple optical sensing capabilities. This tag includes five photodiodes to cover a wide spectral range from near infrared to visible and ultraviolet spectral regions. A microcontroller based switch has been implemented to measure in the same access the five magnitudes coming from the optical sensors, providing a spectral fingerprint of the incident electromagnetic radiation.

Part 4: Testing of Embedded Systems; International audience; Model-based conformance testing of reactive systems consists in taking benefit from the model for mechanizing both test data generation and verdicts computation. On-line test case generation allows one to apply adaptive on-the-fly analyzes to generate the next inputs to be sent and to decide if observed outputs meet intended behaviors. On the other hand, in off-line approaches, test suites are pre-computed from the model and stored under a format that can be later performed on test-beds. In this paper, we propose a two-passes off-line approach where: for the submission part, a test suite is a simple timed sequence of numerical input data and waiting delays, and then, the timed sequence of output data is post-processed on the model to deliver a verdict. As our models are Timed Output Input Symbolic Transition Systems, our off-line algorithms involve symbolic execution and constraint solving techniques.