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11 results on '"Pierdomenico, Anna M."'

4. Prediction of Masked Uncontrolled Hypertension Detected by Ambulatory Blood Pressure Monitoring

Author

Coccina, Francesca, primary, Borrelli, Paola, additional, Pierdomenico, Anna M., additional, Pizzicannella, Jacopo, additional, Guagnano, Maria T., additional, Cuccurullo, Chiara, additional, Di Nicola, Marta, additional, Renda, Giulia, additional, Trubiani, Oriana, additional, Cipollone, Francesco, additional, and Pierdomenico, Sante D., additional

Published
2022
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9. Prognostic Value of Masked Uncontrolled Hypertension

Author

Pierdomenico, Sante D, Pierdomenico, Anna M, Coccina, Francesca, Clement, Denis L, De Buyzere, Marc L, De Bacquer, Dirk A, Ben-Dov, Iddo Z, Vongpatanasin, Wanpen, Banegas, José R, Ruilope, Luis M, Thijs, Lutgarde, and Staessen, Jan A

Subjects
Male, hypertension, blood pressure, Blood Pressure Determination, Middle Aged, Prognosis, mortality, Risk Assessment, Observational Studies as Topic, Outcome Assessment (Health Care), Risk Factors, Cardiovascular Diseases, Masked Hypertension, Humans, Female, risk, Aged
Abstract

The prognostic relevance of masked uncontrolled hypertension (MUCH) is incompletely clear, and its global impact on cardiovascular outcomes and mortality has not been assessed. The aim of this study was to perform a meta-analysis on the prognostic value of MUCH. We searched for articles assessing outcome in patients with MUCH compared with those with controlled hypertension (CH) and reporting adjusted hazard ratio and 95% CI. We identified 6 studies using ambulatory blood pressure monitoring (12 610 patients with 933 events) and 5 using home blood pressure measurement (17 742 patients with 394 events). The global population included 30 352 patients who experienced 1327 events. Selected studies had cardiovascular outcomes and all-cause mortality as primary outcome, and the main result is a composite of these events. The overall adjusted hazard ratio was 1.80 (95% CI, 1.57-2.06) for MUCH versus CH. Subgroup meta-analysis showed that adjusted hazard ratio was 1.83 (95% CI, 1.52-2.21) in studies using ambulatory blood pressure monitoring and 1.75 (95% CI, 1.38-2.20) in those using home blood pressure measurement. Risk was significantly higher in MUCH than in CH independently of follow-up length and types of studied events. MUCH was at significantly higher risk than CH in all ethnic groups, but the highest hazard ratio was found in studies, including black patients. Risk of cardiovascular events and all-cause mortality is significantly higher in patients with MUCH than in those with CH. MUCH detected by ambulatory or home blood pressure measurement seems to convey similar prognostic information.

Published
2018

11. Ambulatory blood pressure and risk of new‐onset atrial fibrillation in treated hypertensive patients.

Author

Coccina, Francesca, Pierdomenico, Anna M., Ianni, Umberto, De Rosa, Matteo, De Luca, Andrea, Pirro, Davide, Pizzicannella, Jacopo, Trubiani, Oriana, Cipollone, Francesco, Renda, Giulia, and Pierdomenico, Sante D.

Abstract

The aim of this study was to evaluate the influence of clinic and ambulatory blood pressure (BP) on the occurrence of new‐onset atrial fibrillation (AF) in treated hypertensive patients. We studied 2135 sequential treated hypertensive patients aged >40 years. During the follow‐up (mean 9.7 years, range 0.4–20 years), 116 events (new‐onset AF) occurred. In univariate analysis, clinic, daytime, nighttime, and 24‐h systolic BP were all significantly associated with increased risk of new‐onset AF, that is, hazard ratio (95% confidence interval) per 10 mm Hg increment 1.22 (1.11–1.35), 1.36 (1.21–1.53), 1.42 (1.29–1.57), and 1.42 (1.26–1.60), respectively. After adjustment for various covariates in multivariate analysis, clinic systolic BP was no longer associated with increased risk of new‐onset AF, whereas daytime, nighttime, and 24‐h systolic BP remained significantly associated with outcome, that is, hazard ratio (95% confidence interval) per 10 mm Hg increment 1.09 (0.97–1.23), 1.23 (1.10–1.39), 1.16 (1.03–1.31), and 1.22 (1.06–1.40), respectively. Daytime, nighttime, and 24‐h systolic BP are superior to clinic systolic BP in predicting new‐onset AF in treated hypertensive patients. Future studies are needed to evaluate whether a better control of ambulatory BP might be helpful in reducing the occurrence of new‐onset AF. [ABSTRACT FROM AUTHOR]

Published
2021
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