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Objective: Thumbtack Needling (TN) has been employed in the treatment of functional constipation (FC), although the existing evidence supporting its effectiveness is limited. This study is to evaluate the efficacy of TN in ameliorating FC. Method: A total of 482 eligible patients were recruited and randomly assigned to the TN group or the Mosapride Citrate (MC) group. The TN was buried once for three days, rest for one day after two consecutive burials, followed by a 4-week follow-up. The primary outcome measure was the score for Complete and spontaneous bowel movement score (CSBMs). Secondary outcome measures included the Bristol Stool Form Scale (BSFS), Cleveland Clinic Score (CCS), and the Patient Assessment of Constipation Quality of Life Questionnaire (PAC-QOL). Results: Out of the 482 patients randomized, 241 were allocated to each group. Of these, 216 patients (89.6 %) in both groups completed the intervention and follow-up. Compared with the baseline, the differences of CSBMs in TN group [1.76(95 % CI, 1.61 to 1.91)] and MC group [1.35(95 % CI, 1.20 to 1.50)] at week 4 meet the threshold for minimal clinically important difference (MCID). However, there were no clinical difference from baseline at week 2 and week 8 in both groups. Mean CSBMs at week 4 was 3.35 ± 0.99 in the TN group and 3 ± 1.03 in the MC group (adjusted difference between groups, 0.37 points [95 % CI, 0.18 to 0.55]; P

Combining proactive literature, the social learning/cognitive theory, and cross-cultural adjustment literature, we examined the sojourners' experience from a positive perspective. Using a three-wave prospective design and a sample of 135 international students, we found that proactive personality was positively related to adjustment self-efficacy, which in turn positively related to academic and social adjustment. Meanwhile, adjustment self-efficacy mediated the link between proactive personality and adjustment. Implications, limitations, and future research are discussed.

Fifty-one surface sediment samples from Dongshan Bay, China, were analyzed for heavy metals to evaluate their distribution, pollution status, and controlling factors. The enrichment factor is suggestive of the potential pollution status, ranging from minimal to moderate enrichment, for Pb, As, Zn, and Hg, with one site showing significant enrichment in As. A principal component analysis and the geochemical characteristics indicate that heavy metal concentrations are mainly influenced by clay minerals and Fe oxides, while Pb and Hg levels are also closely linked to the absorption of Mn oxides. Potential pollution is primarily from aquaculture (Cd, Zn, Cu, Pb) and industrial and domestic discharges. Approximately 270 tons of heavy metals were estimated to have been deposited in Dongshan Bay in 2021, highlighting the potential impact of human activities on coastal sediment quality. [ABSTRACT FROM AUTHOR]

The stability of irrigation water is critical for the sustainability of alpine agriculture. Based on monthly precipitation and terraced field water and spring water samples obtained between 2015 and 2016, the study used the mean residence time and isotope mixing model to analyze the influence of spring water residence time on irrigation water stability in the Hani Rice Terraces. The results indicate that: (1) The mean residence time of precipitation and terraced field water in spring water was 2.46 years and 1.55 years, respectively, implying that the terraced field's irrigation water source could be refilled by spring water recharged 1.5–2.5 years ago. (2) The mean residence time of precipitation in ascending and descending springs was 2.73 years and 1.95 years, respectively. The mean residence time of terraced field water in ascending and descending springs was 1.54 years and 1.04 years, respectively. The ascending spring's recharge water residence time is 0.5–0.8 years longer than that of the descending spring, indicating that the spring water exhibits intra-seasonal and inter-seasonal staggered peak recharging. At the same time, the total recharge period of the ascending–descending spring is extended to 1–3 years, which means the terraced fields have a drought resistance of three years. (3) The mean residence time of precipitation and terraced field water at higher altitudes in the ascending spring is 2.52 times and 3.73 times, respectively, while in the descending spring, it is 3.36 times and 6.49 times to the lower altitude region. This means that the mean residence time of the recharge water source in the lower terraced fields was shorter, and the elevation difference between ascending and descending springs was smaller, thereby regulating the spatial homogeneous distribution of recharge water sources in the terraced fields. [ABSTRACT FROM AUTHOR]

An all-silica Fabry-Pérot interferometer (FPI) is demonstrated for high-temperature pressure monitoring. The pressure sensor is fabricated with single mode fiber and silica capillary by CO2 laser. Owing to slight mismatch of thermal expansion coefficient in all-silica structure, it can work stably under 600°C atmosphere. The influence of the temperature on the pressure sensor was investigated within a temperature range from 25°C to 700°C and a pressure range from standard atmosphere pressure to 4 MPa. The experimental results show that the wavelength shift versus the pressure at each temperature is linear, which indicates the proposed FPI pressure sensor has potential applications in industrial reactors, oil and gas wells, and so on. [ABSTRACT FROM AUTHOR]