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2. Prevalence and risk factors of self-reported hearing loss, tinnitus, and dizziness in a population-based sample from rural northeastern Germany

Author

Friedrich Ihler, Tina Brzoska, Reyhan Altindal, Oliver Dziemba, Henry Völzke, Chia-Jung Busch, and Till Ittermann

Subjects
Medicine, Science
Abstract

Abstract A close anatomical and physiological relationship is known between the senses of hearing and balance, while an additional pathophysiological interaction is supposed. The mechanisms underlying this association are not yet fully understood, especially in individuals without a known specific otologic disorder. In particular, only scarce information on the combined occurrence of audiovestibular sensory impairment is available so far. Therefore, this study aims to provide further insight into the prevalence and co-prevalence of the audiovestibular symptoms hearing loss, tinnitus and dizziness. Additionally, the influence of potential risk factors from lifestyle habits as well as cardiovascular and metabolic conditions on the development of those symptoms is studied. Data was analyzed from 8134 individuals from the population-based Study of Health in Pomerania (SHIP). SHIP pursues a broad and comprehensive examination program in chronologically separated cohorts with longitudinal follow-up. Cohorts are sampled from Western Pomerania, a rural region of north-eastern Germany. The study population represents a cross-sectional analysis from the cohorts SHIP-START (recruited 1997–2001) and SHIP-TREND (recruited 2008–2012), sampled for baseline investigations (SHIP-START-0 and SHIP-TREND-0) at the age of 20–79 years. Audiovestibular symptoms as outcome variables were assessed by structured questionnaires. Additionally, individuals were comprehensively characterized regarding modifiable lifestyle factors as well as cardiovascular and metabolic disorders, allowing the assessment of their role as exposure variables. We calculated a weighted prevalence of 14.2% for hearing loss, 9.7% for tinnitus, and 13.5% for dizziness in the population. Prevalence increased with age and differed among the sexes. A considerable share of 28.0% of the investigated individuals reported more than one symptom at once. The prevalence of hearing loss as well as tinnitus increased between the two cohorts. A moderate positive correlation was found between the occurrence of hearing loss and tinnitus (phi-coefficient 0.318). In multivariable regression analyses, education was identified as a significant protective factor while only smoking was significantly associated with all three symptoms. Furthermore, several cardiovascular risk factors contributed to both hearing loss and dizziness. In conclusion, audiovestibular symptoms are highly prevalent in the investigated population. A considerable but complex influence of risk factors points towards a relation with neuronal as well as cardiovascular disease processes. To clarify the underlying mechanisms, the interaction between the senses of hearing and balance as well as the mode of action of the risk factors should be evaluated in more detail in the future.

Published
2024
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4. Effects of the harvesting technique and external stenting on progression of vein graft disease 2 years after coronary artery bypass

Author

Sandner, SE, Donovan, TJ, Edelstein, S, Puskas, JD, Angleitner, P, Krasopoulos, G, Channon, K, Gehrig, T, Rajakaruna, C, Ladyshenskij, L, De Silva, R, Bonaros, N, Bolotin, G, Jacobs, S, Thielmann, M, Choi, Y-H, Ohri, S, Lipey, A, Friedrich, I, and Taggart, DP

Subjects
Pulmonary and Respiratory Medicine, Medizin, Disease Progression, Humans, Surgery, Saphenous Vein, General Medicine, Coronary Artery Disease, Coronary Artery Bypass, Cardiology and Cardiovascular Medicine, Coronary Angiography, Vascular Patency
Abstract

OBJECTIVES In a post hoc analysis of the VEST III trial, we investigated the effect of the harvesting technique on saphenous vein graft (SVG) patency and disease progression after coronary artery bypass grafting. METHODS Angiographic outcomes were assessed in 183 patients undergoing open (126 patients, 252 SVG) or endoscopic harvesting (57 patients, 114 SVG). Overall SVG patency was assessed by computed tomography angiography at 6 months and by coronary angiography at 2 years. Fitzgibbon patency (FP I, II and III) and intimal hyperplasia (IH) in a patient subset were assessed by coronary angiography and intravascular ultrasound, respectively, at 2 years. RESULTS Baseline characteristics were similar between patients who underwent open and those who underwent endoscopic harvesting. Open compared with endoscopic harvesting was associated with higher overall SVG patency rates at 6 months (92.9% vs 80.4%, P = 0.04) and 2 years (90.8% vs 73.9%, P = 0.01), improved FP I, II and III rates (65.2% vs 49.2%; 25.3% vs 45.9%, and 9.5% vs 4.9%, respectively; odds ratio 2.81, P = 0.09) and reduced IH area (-31.8%; P = 0.04) and thickness (-28.9%; P = 0.04). External stenting was associated with improved FP I, II and III rates (odds ratio 2.84, P = 0.01), reduced IH area (-19.5%; P < 0.001) and thickness (-25.0%; P < 0.001) in the open-harvest group and reduced IH area (-12.7%; P = 0.01) and thickness (-9.5%; P = 0.21) in the endoscopic-harvest group. CONCLUSIONS A post-hoc analysis of the VEST III trial showed that open harvesting is associated with improved overall SVG patency and reduced IH. External stenting reduces SVG disease progression, particularly with open harvesting.

Published
2021

5. Multimodale Therapiekonzepte – Stellenwert der postoperativen Radiotherapie in der chirurgischen Behandlung von Kopf-Hals-Tumoren

Author

Weiss, BG, Bertlich, M, Martin, C, Friedrich, I, and Mark, J

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Fortgeschrittene Tumorerkrankungen erfordern multimodale Therapiekonzepte. Ergänzend zur chirurgischen Therapie kommen postoperativ radio(chemo)therapeutische Behandlungsstrategien zum Einsatz. In onkologischen Zentren werden die Therapiekonzepte heute im interdisziplinären Konsens[zum vollständigen Text gelangen Sie über die oben angegebene URL], Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte

Published
2019
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10. Factors influencing outcomes in selective neck dissection in 661 patients with head and neck squamous cell carcinoma

Author

Mattis Bertlich, Nina Zeller, Saskia Freytag, Jennifer L. Spiegel, Bernhard G. Weiss, Martin Canis, Frank Haubner, and Friedrich Ihler

Subjects
Head and neck squamous cell carcinoma, Neck dissection, Selective neck dissection, Surgery, RD1-811
Abstract

Abstract Background Selective neck dissection (SND) is the surgical treatment of choice in squamous cell carcinoma of the head and neck (HNSCC) with suspected or manifest metastases in the cervical lymph nodes. For SND to be successful, treated lymph node levels should be selected according to anatomic considerations and the extent of the disease. Aim of this study was to identify neck dissection levels that had an impact on individual prognosis. Methods We conducted a retrospective review of SND as part of primary treatment of HNSCC. Overall survival (OS) and regional control rates (RCR) were calculated for all patients treated at one academic tertiary referral center. Results 661 patients with HNSCC were included, 644 underwent ipsilateral and 319 contralateral SND. Average follow-up was 78.9 ± 106.4 months. 67 (10.1%) patients eventually developed nodal recurrence. Tumor sites were oral cavity (135), oropharynx (179), hypopharynx (118) and larynx (229). Tumor categories pT1–pT4a, and all clinical and pathological nodal categories were included. Multivariate analysis indicated improved OS rates for patients undergoing SND in ipsilateral levels I and V as well as level III contralaterally. Analysis for tumor origin showed that SND in ipsilateral level I showed significantly improved OS in HNSCC of the oral cavity. Conclusion The dissection of ipsilateral level I in oral cavity cancer was of particular relevance in our exploratory, retrospective analysis. To clarify the relevance for the determination of the extent of SND, this should be investigated prospectively in a more homogenous patient cohort.

Published
2022
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11. Coronary-artery bypass surgery in patients with left ventricular dysfunction

Author

Velazquez, E, Lee, K, Deja, Ma:, J, A, Sopko, G, Marchenko, A, Ali, I, Pohost, G, Gradinac, S, Abraham, W, Yii, M, Prabhakaran, D, Szwed, H, Ferrazzi, P, Petrie, M, O'Connor, C, Panchavinnin, P, She, L, Bonow, R, Rankin, G, Jones, R, Rouleau, J, Cherniavsky, A, Romanov, A, Wos, S, Deja, M, Golba, K, Malinowski, M, Kosevic, D, Vukovic, M, Djokovic, L, Krzeminska Pakula, M, Jaszewski, R, Drozdz, J, Chrzanowski, L, Rajda, M, Howlett, J, Macfarlane, M, Jain, A, Shah, H, Rakshak, D, Saxena, A, Zembala, M, Przybylski, R, Kukulski, T, Wasilewski, J, Wiechowski, S, Brykczynski, M, Kurowski, M, Mokrzycki, K, Sadowski, J, Kapelak, B, Sobczyk, D, Plicner, D, Wrobel, K, Piegas, L, Paulista, P, Farsky, P, Veiga Kantorowitz, C, Sadowski, Z, Juraszynski, Z, Dabrowski, R, Rogowski, J, Pawlaczyk, R, Rynkiewicz, A, Betlejewski, P, Siepe, M, Geibel Zehender, A, Cuerten, C, Higgins, R, Crestanello, J, Binkley, P, Jones, D, Sun, B, Smith, P, Milano, C, Adams, P, Hill, J, Beaver, T, Leach, D, Airan, B, Das, S, Prior, D, Mack, J, Rao, V, Iwanochko, R, Renton, J, Phuangkaew, N, Bochenek, A, Krejca, M, Trusz Gluza, M, Wita, K, Gavazzi, A, Senni, M, Natarajan, S, Padmanabhan, C, Racine, N, Bouchard, D, Ducharme, A, Brown, H, Alotti, N, Lupkovics, G, Kumar, S, Agarwal, S, Sinha, N, Rai, H, Andersson, B, Janssen, A, Lamy, A, Demers, C, Rizzo, T, Doenst, T, Garbade, J, Thiele, H, Richter, M, Murday, A, Shaw, M, Raju, K, Mannam, G, Reddy, G, Rao, K, Nicolau, J, Stolf, N, Vieira, A, Chua, Y, Lim, C, Kwok, B, Gan, Y, Cleland, J, Cale, A, Thackray, S, Lammiman, M, Michler, R, Swayze, R, Maurer, G, Grimm, M, Lang, I, Adlbrecht, C, Daly, R, Rodeheffer, R, Nelson, S, Larbalestier, R, Wang, X, Haddad, H, Hendry, P, Donaldson, J, Menicanti, L, Di Donato, M, Castelvecchio, S, Sirvydis, V, Voluckiene, E, Di Benedetto, G, Attisano, T, Favaloro, R, Favaloro, L, Diez, M, Riccitelli, M, Picone, V, Koslowski, P, Gaito, M, Al mohammad, A, Braidley, P, Steele, H, Nawarawong, W, Woragidpoonpol, S, Kuanprasert, S, Mekara, W, Kon, N, Hammon, J, Wells, G, Tilley, W, Drazner, M, Di Maio, M, Peschka, S, Pasquale, D, Knight, C, J, Aylward, P, Thomas, C, Gullestad, L, Sorensen, G, Kaul, U, Gupta, R, Schmedtje, Jj, Arnold, S, Wilson, V, Grayburn, P, Hamman, B, Hebeler, R, Aston, S, Birjiniuk, V, Harrington, M, Dupree, C, Sheridan, B, Schuler, C, Helou, J, Denis, I, Bigalli, D, Gutierrez, F, Russo, N, Batlle, C, White, H, Alison, P, Stewart, R, Borthwick, L, Philippides, G, Shemin, R, Fitzgerald, C, Dagenais, F, Dussault, G, Kamath, P, Busmann, C, Ferrari, G, Botto, M, Horkay, F, Hartyanszky, I, Bartha, E, Simor, T, Papp, L, Toth, L, Varga Szemes, A, Szekely, L, Keltai, M, Edes, I, Szathmarine, V, Yakub, M, Sarip, S, Maitland, A, Isaac, D, Holland, M, Bogats, G, Csepregi, L, Maia, L, Soares, M, Mouco, O, Souza, A, da Rocha, A, Brito, J, Pitella, F, Camara, A, Horowitz, J, Knight, J, Rose, J, Mcrae, Rj, Geiss, D, Clemson, B, Pierson, M, Kron, I, Kern, J, Bergin, J, Phillips, J, Rich, J, Herre, J, Pine, L, Chin, D, Spyt, T, Logtens, E, Amuchastegui, L, Bracco, D, Ruengsakulrach, P, Pitiguagool, V, Sukhum, P, Srinualta, D, Hayward, C, Herrera, C, Zimmermann, R, Patterson, G, Stephens, W, Dignan, R, French, J, Sequalino, N, Vaishnav, S, Panda, R, Chavan, A, Benetis, R, Jankauskiene, L, Kalil, R, Nesralla, I, Santos, M, de Moraes, M, Friedrich, I, Buerke, M, Paraforos, A, Konda, S, Leone, C, Murphy, E, Ravichandran, P, Avalos, K, Hetzer, R, Knosalla, C, Hoffmann, K, Landolfo, K, Landolfo, C, Park, M, Chiariello, L, Nardi, P, Stapleton, D, Hoey, K, Hasaniya, N, Wang, N, Bijou, R, Naka, Y, Ascheim, D, Mikati, I, Arnold, M, Mckenzie, N, Smith, J, Gheorghiade, M, Fullerton, D, Roberts, L, Carson, P, Miller, A, Pina, I, Selzman, C, Wertheimer, J, Goldstein, S, Cohn, F, Hlatky, M, Kennedy, K, Rankin, S, Robbins, R, Zaret, B, Barfield, T, Desvigne Nickens, P, Oh, J, Panza, J, Apte, P, Doyle, M, Forder, J, Ocon, M, Pai, R, Reddy, V, Santos, N, Tripathi, R, Varadarajan, P, Pellikka, P, Miller, Fj, Lin, G, Borgeson, D, Ommen, S, Casaclang Verzosa, G, Miller, D, Springer, R, Blahnik, F, Manahan, B, Welper, J, Wiste, H, Mark, D, Anstrom, K, Baloch, K, Burnette, A, Cowper, P, Davidson Ray, N, Drew, L, Harding, T, Hunt, V, Knight, D, Patterson, A, Redick, T, Sanderford, B, Feldman, A, Bristow, M, Chan, T, Maisel, A, Mann, D, Mcnamara, D, Holly, T, Berman, D, Leonard, S, Helmer, D, Woods, M, Mcnulty, M, Asch, F, Rumsey, M, Bieganski, S, Roberts, B, Handschumacher, M, Mccormick, A, Albright, J, Dandridge, R, Rittenhouse, L, Wagstaff, D, Williams, M, Bailey, D, Glover, D, Parrish, L, Wakeley, N, Jackson, V, Nicholson, B, Mcdaniel, A, Al Khalidi, H, Greene, D, and Moore, V

Subjects
Male, medicine.medical_specialty, Coronary Artery Disease, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, law.invention, Coronary artery disease, 03 medical and health sciences, Coronary artery bypass surgery, Ventricular Dysfunction, Left, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, medicine, Clinical endpoint, Humans, 03.02. Klinikai orvostan, cardiovascular diseases, 030212 general & internal medicine, Coronary Artery Bypass, Aged, Proportional Hazards Models, Heart Failure, Intention-to-treat analysis, Proportional hazards model, business.industry, Hazard ratio, Settore MED/23 - Chirurgia Cardiaca, General Medicine, Middle Aged, medicine.disease, Combined Modality Therapy, 3. Good health, Surgery, Intention to Treat Analysis, Hospitalization, surgical procedures, operative, Cardiovascular Diseases, Heart failure, Cardiology, Female, business
Abstract

The role of coronary-artery bypass grafting (CABG) in the treatment of patients with coronary artery disease and heart failure has not been clearly established.Between July 2002 and May 2007, a total of 1212 patients with an ejection fraction of 35% or less and coronary artery disease amenable to CABG were randomly assigned to medical therapy alone (602 patients) or medical therapy plus CABG (610 patients). The primary outcome was the rate of death from any cause. Major secondary outcomes included the rates of death from cardiovascular causes and of death from any cause or hospitalization for cardiovascular causes.The primary outcome occurred in 244 patients (41%) in the medical-therapy group and 218 (36%) in the CABG group (hazard ratio with CABG, 0.86; 95% confidence interval [CI], 0.72 to 1.04; P=0.12). A total of 201 patients (33%) in the medical-therapy group and 168 (28%) in the CABG group died from an adjudicated cardiovascular cause (hazard ratio with CABG, 0.81; 95% CI, 0.66 to 1.00; P=0.05). Death from any cause or hospitalization for cardiovascular causes occurred in 411 patients (68%) in the medical-therapy group and 351 (58%) in the CABG group (hazard ratio with CABG, 0.74; 95% CI, 0.64 to 0.85; P

Published
2011

12. Erratum zu: Deutsch-österreichische S3-Leitlinie 'Infarktbedingter kardiogener Schock – Diagnose, Monitoring und Therapie', Intensivmedizin und Notfallmedizin (2011) 48:291–344, http://dx.doi.org/10.1007/s00390-011-0284-8

Author

Werdan, K., Ruß, M., Buerke, M., Engelmann, L., Ferrari, M., Friedrich, I., Geppert, A., Graf, J., Hindricks, G., Janssens, U., Pieske, B. M., Prondzinsky, R., Reith, S., Trappe, H.-J., Zehender, M., Zerkowski, H.-R., Zeymer, U., Adams, H. A., Briegel, J., Delle-Karth, G., Schöndube, F. A., Schwaab, B., Bode, C., Christoph, A., Erbel, Raimund, Fuhrmann, J. T., Strasser, R., Figulla, H.-R., Görge, G., Schmitt, D., Schuler, G., Silber, R.-E., Tebbe, U., and Zwißler, B.

Subjects
Medizin
Published
2011

13. Universal newborn hearing screening. Definition of uniform parameters by the Association of German Hearing Screening Centers as a requirement for nationwide evaluation with valid results

Author

Brockow, I., Praetorius, M., Neumann, K., Zehnhoff-Dinnesen, A. Am, Mohnike, K., Matulat, P., Rohlfs, K., Lang-Roth, R., Gross, M., Duphorn, E., Meuret, S., Seidel, A., Schonfeld, R., Schonweiler, R., Dienlin, S., Rissmann, A., Friedrich, I., Lehnert, B., Nennstiel-Ratzel, U., Brockow, I., Praetorius, M., Neumann, K., Zehnhoff-Dinnesen, A. Am, Mohnike, K., Matulat, P., Rohlfs, K., Lang-Roth, R., Gross, M., Duphorn, E., Meuret, S., Seidel, A., Schonfeld, R., Schonweiler, R., Dienlin, S., Rissmann, A., Friedrich, I., Lehnert, B., and Nennstiel-Ratzel, U.

Abstract

Since 2009, all newborns in Germany have been entitled to universal neonatal hearing screening (UNHS). UNHS with tracking of test results leads to earlier detection of hearing disorders. The Association of German Hearing Screening Centers (Verband Deutscher Horscreening-Zentralen, VDHZ) was founded to promote nationwide tracking, validity and quality control of UNHS results. A comparable data structure in the different screening centers, with uniform definitions of primary parameters is essential for the nationwide evaluation of UNHS results. To address the question of whether a data structure with comparable definitions already exists or still has to be created, the existing structures and primary parameter definitions in the hearing screening centers should be investigated and compared. A survey was conducted in all hearing screening centers to assess how data on the primary UNHS parameters defined in pediatric guidelines was gathered. In the case of discrepancies, uniform definitions were created. Finally, the practicability of these definitions was evaluated. Due to differing definitions of primary parameters, some of the data were not comparable between the individual centers. Therefore, uniform definitions were created in a consensus process. In the centers, the screening method, the two-step first screening and the result of the first screening now correspond to these uniform definitions. Other parameters, e.g. the total number of newborns, still vary widely, rendering the comparison of screening rates almost impossible. Valid evaluation of UNHS not only requires nationwide establishment of hearing screening centers, but also unified data structures and parameter definitions.

Published
2014

14. HeartMate II left ventricular assist device; early European experience

Author

Strüber, M. Sander, K. Lahpor, J. Ahn, H. Litzler, P.-Y. Drakos, S.G. Musumeci, F. Schlensak, C. Friedrich, I. Gustafsson, R. Oertel, F. Leprince, P.

Abstract

Objective: The novel axial flow left ventricular assist device HeartMate II was introduced into clinical practice in Europe as part of the pilot study and after CE approval in November 2005. In order to get an overview of the use and performance of the device in Europe a group of investigators was founded to compare the initial results. Methods: In a retrospective analysis of the first 101 consecutive cases in Europe, data were collected with regard to postoperative outcome and severe adverse events and anticoagulation protocols. Results were stratified by intention to treat as a bridge to transplant or as chronic support therapy in heart failure (destination therapy). Results: In 70% of patients, the HeartMate II was intended as a bridge to transplant therapy, in 30%, it was used as a destination therapy device. The perioperative mortality post implant was 20% in the bridge to transplant patients and 7% in the destination therapy arm. However, after 1 year a comparable survival was observed in both groups (69% destination therapy, 63% bridge to transplant). Main causes of death were multiple organ failure (n = 12) and cerebrovascular accidents (n = 5). All, but one cerebrovascular accident occurred in the first 9 days after surgery. Only one other death was reported thereafter and there was no mechanical failure of the device. Conclusions: Even in the early experience the HeartMate II was used as a chronic support device in a substantial number of patients in Europe. Although the total experience is still limited, the incidence of cerebrovascular accidents is very low and the survival beyond the perioperative period is excellent. © 2008 European Association for Cardio-Thoracic Surgery.

Published
2008

16. Optische Datenspeicherung mit Phasenwechselmedien: Präparation und Charakterisierung von GeSbTe-Schichten

Author

Friedrich, I.

Abstract

Data storage plays a major role in information technology. The further development of thecompact disc for mass storage does not only require an increase of the data density butalso the ability to delete or to rewrite data. Phase change materials have a high potentialfor rewriteable optical date storage. The aim of this thesis is to investigate and comparethe material's properties of Ge$_{2}$Sb$_{1}$Te$_{5}$ (PC1) and Ge$_{4}$Sb$_{1}$Te$_{5}$ (PC2) with regard to therequirements of data storage application. The large change of the electrical resistance is used to investigate the phase changekinetics. Accompanying x-ray diffraction measurements show that PC1 undergoes a phasetransitions from an amorphous to a cubic phase and a second to a hexagonal phase. On thecontrary, PC2 shows only one transition from amorphous to fcc. The cubic phase of bothalloys agrees qualitatively to a NaCl- structure but for PC1 a high density of vacanciesis postulated. The optical contrast between the two crystalline phases of PC1 is small(4.5%) compared to that between the amorphous and the fcc-phase (66%). Nevertheless,selected area (electron) diffraction showed clearly the fcc-character of laser modified areas.Measurements on PC-films with a thin ZnS-SiO$_{2}$ layer on top show that the impact ofthe dielectric layer an the phase change properties of both alloys is not neglectable.

Published
2000

17. Warhafftiger Abdruck und Copey, einer abschrifft, So unlangst der Antichrist der Bapst zu Rom, an die dreyzehen ort inn Schweitz gethan, daraus klerlich zu verstehn, warumb Key. May. itzige kriegsrüstung fürgenommen] Warhafftiger Abdruck vnd Copey/|| einer abschrifft/ So vnlangst der Antichrist|| der Bapst zu Rom/ an die dreyzehen ort inn|| Schweitz gethan/ daraus klerlich zu-||uerstehen/ warumb Key. May. jtzi-||ge kriegsrüstung für-||genomen.|| / [Paulus Papa Tertius.

Author

Johann Friedrich I., Sachsen, Kurfürst, Philipp I., Hessen, Landgraf, Paulus III., Papst, Johann Friedrich I., Sachsen, Kurfürst, Philipp I., Hessen, Landgraf, and Paulus III., Papst

Published
2009

18. Warhafftiger Abdruck und Copey, einer abschrifft, So unlangst der Antichrist der Bapst zu Rom, an die dreyzehen ort inn Schweitz gethan, daraus klerlich zu verstehn, warumb Key. May. itzige kriegsrüstung fürgenommen] Warhafftiger Abdruck vnd Copey/|| einer abschrifft/ So vnlangst der Antichrist|| der Bapst zu Rom/ an die dreyzehen ort inn|| Schweitz gethan/ daraus klerlich zu-||uerstehen/ warumb Key. May. jtzi-||ge kriegsrüstung für-||genomen.|| / [Paulus Papa Tertius.

Author

Johann Friedrich I., Sachsen, Kurfürst, Sachsen, Kurfürst, Philipp I., Hessen, Landgraf, Paulus III., Papst, Johann Friedrich I., Sachsen, Kurfürst, Sachsen, Kurfürst, Philipp I., Hessen, Landgraf, and Paulus III., Papst

Published
2009

20. Population Based Average Parotid Gland Volume and Prevalence of Incidental Tumors in T1-MRI

Author

Tina Brzoska, Till Ittermann, Friedrich Ihler, Carmela Koch, Markus Blaurock, Robin Bülow, Henry Völzke, Chia-Jung Busch, and Achim Georg Beule

Subjects
salivary gland volume, population-based imaging, whole-body magnetic resonance imaging, parotid gland tumors, Medicine
Abstract

Representative epidemiologic data on the average volume of the parotid gland in a large population-based MRI survey is non-existent. Within the Study of Health in Pomerania (SHIP), we examined the parotid gland in 1725 non-contrast MRI-scans in T1 weighted sequence of axial layers. Thus, a reliable standard operating procedure (Intraclass Correlation Coefficient > 0.8) could be established. In this study, we found an average, single sided parotid gland volume of 27.82 cm3 (95% confidence interval (CI) 27.15 to 28.50) in male and 21.60 cm3 (95% CI 21.16 to 22.05) in female subjects. We observed positive associations for age, body mass index (BMI), as well as male sex with parotid gland size in a multivariate model. The prevalence of incidental tumors within the parotid gland regardless of dignity was 3.94% in the Northeast German population, slightly higher than assumed. Further epidemiologic investigations regarding primary salivary gland diseases are necessary.

Published
2022
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21. Treatment of active rheumatoid arthritis with leflunomide: two year follow up of a double blind, placebo controlled trial versus sulfasalazine.

Author

Scott, D.L., Smolen, J.S., Kalden, J.R., Putte, L.B.A. van de, Larsen, A., Kvien, T.K., Schattenkirchner, M., Nash, P., Oed, C., Loew-Friedrich, I., Scott, D.L., Smolen, J.S., Kalden, J.R., Putte, L.B.A. van de, Larsen, A., Kvien, T.K., Schattenkirchner, M., Nash, P., Oed, C., and Loew-Friedrich, I.

Abstract

Item does not contain fulltext, OBJECTIVE: Recent studies have demonstrated the short term efficacy of leflunomide. This study evaluates the efficacy and safety of leflunomide and sulfasalazine in rheumatoid arthritis over a two year follow up period. METHODS: 358 patients with rheumatoid arthritis in a double blind trial were randomly allocated to receive either leflunomide 20 mg/day, placebo, or sulfasalazine 2 g/day. Those completing six months of treatment (n=230) were given the option to continue in 12 (n=168) and 24 (n=146) month double blinded extensions; the placebo group switched to sulfasalazine. This report compares efficacy and safety of leflunomide with sulfasalazine in the 6, 12, and 24 month patient cohorts. RESULTS: The efficacy seen at six months was maintained at 12 and 24 months. Twenty four month cohorts on leflunomide showed significant improvement compared with sulfasalazine in doctor (-1.46 v -1.11, p=0.03) and patient (-1.61 v -1.04, p<0.001) global assessments, ACR20% response (82% v 60%, p<0.01), and functional ability (Deltamean HAQ -0.65 v -0.36, p=0.0149; DeltaHAQ disability index -0.89 v -0.60, p=0.059). Improvement in other variables was comparable for the two drugs, including slowing of disease progression. Improved HAQ scores in 6, 12, and 24 month leflunomide cohorts were seen in both non-responders (24%, 29%, 35%, respectively v sulfasalazine 8%, 10%, 27%) and ACR20% responders (leflunomide 63%, 62%, 66% v sulfasalazine 50%, 64%, 44%). Leflunomide is well tolerated at doses of 20 mg. No unexpected adverse events or late toxicity were noted during the two year period. Diarrhoea, nausea, and alopecia were less frequent with continued treatment. CONCLUSION: These long term data confirm that leflunomide is an efficacious and safe disease modifying antirheumatic drug.

Published
2001

24. A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis

Author

Emery, P., primary, Breedveld, F. C., additional, Lemmel, E. M., additional, Kaltwasser, J. P., additional, Dawes, P. T., additional, Gömör, B., additional, Van den Bosch, F., additional, Nordström, D., additional, Bjørneboe, O., additional, Dahl, R., additional, Hørslev‐Petersen, K., additional, Rodriguez de la Serna, A., additional, Molloy, M., additional, Tikly, M., additional, Oed, C., additional, Rosenburg, R., additional, and Loew‐Friedrich, I., additional

Published
2000
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27. Cardiac surgery in the elderly patient.

Author

Friedrich I, Simm A, Kötting J, Thölen F, Fischer B, and Silber R

Abstract

Background: As life expectancies rise and the number of persons over age 75 in the population increases, the proper treatment of elderly cardiac patients is becoming a matter of ever greater medical and political importance. Methods: In collaboration with the German Federal Quality Assurance Office (Bundesgeschäftsstelle Qualitätssicherung, BQS), the authors analyzed the risk profiles of elderly patients by means of data sets from all cardiac surgical centers in Germany for the year 2007. The results regarding risk distribution and the morbidity and lethality statistics for isolated coronary surgery were derived from the complete, nationwide BQS data pool, containing information on a total of 47 881 operations. Data on quality of life and long-term survival were obtained from a selective literature search using Medline. Results: Compared to patients under age 65, those over age 75 have significantly more prognosis-determining comorbidities and risk factors. Accordingly, complication rates and lethality are higher in the latter age group (for example, there is a 4.3-fold relative risk elevation for renal dysfunction, a 3.0-fold elevation for neurological complications, and 3.7-fold elevation for in-hospital lethality). The patient's chronological age is a risk factor for lethality and morbidity after coronary surgical procedures. Conclusions: The lethality risk of a bypass operation can be predicted very accurately with the aid of modern scoring systems. Successful cardiac surgical procedures can return the patient to a normal life expectancy and quality of life for his or her age group. [ABSTRACT FROM AUTHOR]

Published
2009
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29. Zehen Merckwürdige und Heldenmüthige Friedriche, Wurden Dem Durchlauchtigsten Fürsten und Herrn, Herrn Friedrich Erdmann, Hertzogen zu Sachsen, Jülich, Cleve, Berg, auch Engern und Westphalen, Landgraffen in Thüringen, Marggraffen zu Meißen, auch Ober- und Nieder-Lausitz ... Als Seine HochFürstliche Durchl. Am 1. Octobr. MDCCI. Dero Zehndtes Jahr In hohen Wohlergehen zurück legten; Aus dem Hoch-Fürstlichen Stamm-Register Des Durchlauchtigsten Hauses Sachsen Auf den gewöhnlichen Jahr-Kuchen vorgestellet, Und Mit einem unterthänigsten Wunsch begleitet

Author

Friedrich <II., Meißen, Markgraf>, Fridericus <Strenuus>, Friedrich <I., Sachsen, Herzog, Kurfürst>, Friedrich <II., Sachsen, Kurfürst>, Friedrich <III., Sachsen, Kurfürst>, Johann Friedrich <I., Sachsen, Kurfürst>, Fridericus Wilhelmus <Pius>, Fridericus <Belgicus>, Fridericus Wilhelmus <Generosus>, Friedrich <I., Meißen, Markgraf>, Friedrich <II., Meißen, Markgraf>, Fridericus <Strenuus>, Friedrich <I., Sachsen, Herzog, Kurfürst>, Friedrich <II., Sachsen, Kurfürst>, Friedrich <III., Sachsen, Kurfürst>, Johann Friedrich <I., Sachsen, Kurfürst>, Fridericus Wilhelmus <Pius>, Fridericus <Belgicus>, Fridericus Wilhelmus <Generosus>, and Friedrich <I., Meißen, Markgraf>

Abstract

Geburtstagsglückwunsch auf Friedrich Erdmann, Herzog von Sachsen-Merseburg, 1. Okt. 1701, Enth. 11 Glückwünsche der Beiträger, Vorlageform des Erscheinungsvermerks: Merseburg, Druckts Christian Gottschick, Fürstl. Sächs. privilegirter Hoff-Buchdrucker.

30. Insana Pij Pont. Bulla, qua statuit contra || fas, & sensum naturę, non esse a Papa || ad Conciliũ prouocandũ.|| Responsio, & Appellatio Gregorij || Heimburg.|| Immodesta Adriani Pont. Epistola ad || D. Fridericũ Barbarossam Imp.|| D. Friderici Responsio.

Author

Friedrich <I., Heiliges Römisches Reich, Kaiser>, Hadrian <IV., Papst>, Heimburg, Gregorius, Katholische Kirche, Papst Pius II., Deutschland, Kaiser Friedrich I., Katholische Kirche, Papst Hadrian IV., Pius <II., Papst>, Friedrich <I., Heiliges Römisches Reich, Kaiser>, Hadrian <IV., Papst>, Heimburg, Gregorius, Katholische Kirche, Papst Pius II., Deutschland, Kaiser Friedrich I., Katholische Kirche, Papst Hadrian IV., and Pius <II., Papst>

Abstract

[Pius, II., Papa ; Friedrich, I., Heiliges Römisches Reich, Kaiser ; Hadrianus, IV., Papa ; Heimburg, Gregorius], Berichtigte Aufmahme., Signaturformel: a6, Vorlageform des Erscheinungsvermerks: [Wittenberg: Johann Rhau- Grunenberg um 1520]

31. Ein warhafftige Co=||pey einer Schrifft/ so der Durch=||leuchtigste Hochgeborne Fürst vnd Herr/ Herr || Johans Friderich/ Hertzog zu Sachssen/|| Churfürst/ vnd Burggraff zu Magde=||burg/ An gemeine Hertzog Moritzen || zu Sachssen Landtschafft/|| gethan || ...

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Im gedruckten VD16 noch ohne Druckort-/Druckerbestimmung., Vorlageform des Erscheinungsvermerks: M.D.XLVII.||[Erfurt: Wolfgang Stürmer]

34. Der Durchlauchtig=||sten vnd Durchlauchtigen Hochgebor=||nen Fürsten vnd herrn/ herrn Johans Fridrichen/|| Hertzogen zu Sachssen/ des heiligen Römischen || Reichs Ertzmarschalh ... || ... Vnd herrn || Philipsen/ Landgrauen zu Hessen/ Grauen zu || Catzenellnbogen ... || Antwort/|| Der Römischen Königlichen Maiestat/ auch Keiserlichen Maiestat || Commissarien/ vnd der Reichstende/ so auff jtzigem Reichstag || zu Nürnberg vorsamlet/ botschafften/ auff jre werbunge/|| der Kriegshandlung halben/ wider Hertzog Heinrichen/|| der sich den Jüngern von Braunschweig thut nennen/|| durch die hülffe Gottes vorgenomen/ gegeben.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Verbesserte Neuaufnahme; in Abt. I u. III Drucker und Druckort nicht ermittelt., Vorlageform des Erscheinungsvermerks: Anno. M.D.XLII.|| [Wittenberg: Georg Rhau]

35. Perdis mendaces, sanguinarios, & frau=||dulentos abominaris Domine.|| Vrsach/ Warumb von || Gottes gnaden wir Johans Fride=||rich Hertzog zů Sachsen/ des Heiligen Römischen || Reichs Ertzmarschalh vnd Churfürst/ Landtgraue in || Doringen ... || Vnd Philips Landtgraue zů Hes=||sen ... Jn namen ge=||meiner verstendtnus/ Die Stet Goßlar/ vñ || Braunschweigk vor dem grausamenn ge=||walt/ Heinrichs/ der sich nennet den || Jüngern Hertzogen zů Braun=||schweig vnnd Lüneburg/|| beschirmen/ schützen/|| vnnd retten || müssen.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: [Straßburg: Wendelin Rihel 1542]

36. DEr dürch||lauchtig=||sten vnd Dur=||chlauchtigen/ Hoch||gebornen Fürsten vñ || herrn/ Herrn Jo=||hans Fridrichen/|| Hertzogen zu Sachs||sen/ Des Heiligen || Römischen Reichs || Ertzmarschalck/|| Churfürsten ... || Vnd herrn Philipssen/ Landgrauen zu || Hessen/ Grauen zu Catzenelnbogen/ Dietz/ Zie=||genhain vnd Nidda/ Widerschreiben/ auff || das vnerfindlich/ Hertzog Heinrichs || zu Braunschwig schreiben ...

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Signaturformel: A-N4, O2, P4 [Bl. P4 leer], Vorlageform des Erscheinungsvermerks: (1539.||?) [Wolfenbüttel: Henning Rüdem]

37. Christliche || Bestendige Bekentnis || vnd abschlegige Antwort auffs Jnterim/|| des Durchleuchtigsten Hochgebornen Fürsten vnd || Herrn/ Herrn Johans Friderichen des Eldern/ Chur=||Fürsten zu Sachsen etc.hochlöblicher Ge=||dechtnis/ Gott vnd jme zu Ehren/|| vnd andern zum Exem=||pel/ ausgangen.|| ...

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: Gedruckt zu Jhena/ Durch Thomas || Rewart/ Anno 1558.

38. MEiner genedigsten || vnnd genedigen Herren Hertzog Jo=||hans Friderichen Churfürsten zů Sachssen #[et]c. Vnd || Herren Philipsen Landgrauen zů Hessen #[et]c. Warhafftige || außfürung/ das Marggraue Hansen von Branden=||burg nit gebürt/ sich in der Keyserlichen Maye=||stat dienst/ wider jr Chur vnnd Fürstliche || gnad/ vnnd ander derselbe Religions || verwandte einzůlassen/ noch || darinn zůuerharren.|| Sampt Bapst Pauli des || Dritten Gottloß gyfftig schreiben/ an || gemaine Aydgnossen/ wellichs die falsch verplö=||mung dises Kriegs gentzlich auffhebt.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: Anno M.D.XLVI.||[Ulm: Hans Varnier]

39. Von Gottes gnadẽ Jo||hanns Friderich/ Her=||tzog zu Sachssen/ Philips Land=||graue zu Hessen/ vnd gemeyner || Christlicher eynung veror=||nete Kriegs Rethe.|| An Hertzogen Wilhel=||men zu Bayern.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Berichtigte Aufnahme., Im gedruckten VD16 noch ohne Druckort-/Druckerbestimmung., Vorlageform des Erscheinungsvermerks: (Anno || 1546.||) [Zwickau: Wolfgang Meyerpeck d.Ä.]

40. Des Churfürsten zu || Sachssen etc. Vnd Burg||grauen zu Magdeburg/ Vnd Phi=||lips Landgrauen zu Hessen/ Verwar||nung/ an die Protestirende Stende/ der Augspurgischen || Confession/ vnnd derselbigen Vnderthanen/|| von wegen des Babsts/ welcher die Was=||ser/ Brunn/ Teiche/ vnd Weide zu||uergifften/ vnd dadurch Leu=||ten vnnd Viehe schaden || zuzufügen verordent.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Vorlageform des Erscheinungsvermerks: [Zwickau: Wolfgang Meyerpeck 1546]

41. Des Churfürsten || zu Sachssen etc. Vnd Burg=||grauen zu Magdeburg.|| Landts Ordenung/|| Von vbermessiger Kleidung/ ge||schmuck/ vnd beköstigung der Hochzeit=||ten/ Kindtauffen/ vnd ande=||rer Gastereien halben.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: 1546.||[Zwickau: Wolfgang Meyerpeck]

42. Der Durchlauchtigst || vnd Durchlauchtigen Hochgebornen || Fürsten vnd herrn/ herrn/ Johans Friderichen/ Hertzogen zu || Sachssen ... || vnd Churfürsten ... || Vnnd Herrn || Philipsen Landgrauen zu Hessen ... || Warhafftiger bericht vnd || Summari außführung/ Warumb jhnen zu vnschulden auff=||gelegt wirdet/ das sie Römischer Key. May. vngehorsame || Fürsten sein solten/ Das sie auch keins ... vngehor=||sams beziegen mögen werden/ anders/ dann das sie von ... || der reinen lere ... nit können || abstehen/ Noch dieselb ... dem Bapst || ... zurichten vnterwerfen.|| ...

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Vorlageform des Erscheinungsvermerks: 1546.||[Erfurt: Melchior Sachse d.Ä.]

43. Vrtheyl/ So Keyser=||liche Maiestat/ vber den gewesenen || Churfürsten von Sachsen decernirt || vnd gesprochen hat.|| Vertrag zwischen Keyser. Maiestat/|| vnd dem gewesenen Churfürsten von || Sachsen.|| Copey der abforderung des krigs=||volcks in der besatzung zu Wit=||tenberg.|| Verzeichnus der gefangenen/ so mit || Hertzog Johans Friderichen von Sachsen dem || Eltern/ vnd gewesenen Churfürsten/ in || seiner niderlag gefangen wor=||den sein.

Author

Deutschland, Kaiser Karl V., Sachsen-ernestinische Linie, Herzog Johann Friedrich I., Karl <V., Heiliges Römisches Reich, Kaiser>, Johann Friedrich <I., Sachsen, Kurfürst>, Deutschland, Kaiser Karl V., Sachsen-ernestinische Linie, Herzog Johann Friedrich I., Karl <V., Heiliges Römisches Reich, Kaiser>, and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: ANNO XLVII.||[s.l.]

44. Der Durchlauchtig=||sten vnd Durchlauchtigen Hochge=||bornen Fürsten vnd herrn/ herrn Johans Fri=||drichen/ Hertzogen zu Sachssen/ des heiligen || Römischen Reichs Ertzmarschalh ... || ... Vnd herrn Philipsen/ Landgrauen zu || Hessen Grauen zu Catzenellnbogen ... || Antwort/ der Römischen Kö=||niglichen Maiestat/ auch Keiserlichen Mai. Com=||missarien/ vnd der Reichsstende/ so auff jtzigem || Reichstag zu Nürnberg vorsamlet/ botschafften/|| auff jhre werbunge/ der Kriegshandlung halben/|| wider Hertzog Heinrichen/ der sich den Jüngern || von Braunschweig thut nennen/ durch die || hülffe Gottes vorgenomen/ gegeben.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Im gedruckten VD16 noch ohne Druckort-/Druckerbestimmung., Vorlageform des Erscheinungsvermerks: Jm Jar || 1542.||[Magdeburg: Hans Walther und Christian Rödinger d.Ä.]

46. EJn warhafftige || Copey einer Schrifft/ So der || Durchleuchtigst Hochgeborne || Fürst vnd Herr/ Herr Johans || Friederich/ Hertzog zu Sachs=||senn/ Churfürst/ vnnd Burg=||graffe zu Magdeburg. An Her=||tzog Moritzen zu Sachssen/ ge=||meiner Landschafft semptlich vnd || sonderlich zu antworten/ vnd || zuzubringen abge=||fertigt.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: M.D.XLVII.||[Erfurt: Melchior Sachse d.Ä.]

47. Von Gottes || gnaden Johannes Friderich || Hertzog zu Sachssen/ Philipps || Landgraue zu Hessen/ vnd || gemeiner Christlicher ei=||nung verordnete Krie=||gs Rethe.|| An Hertzogen Wilhelm || zu Bayern.|| M.D.XLVI.|| Den iij. Augusti.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Johann Friedrich <I., Sachsen, Kurfürst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., and Johann Friedrich <I., Sachsen, Kurfürst>

Abstract

Vorlageform des Erscheinungsvermerks: [Erfurt: Merten von Dolgen 1546]

48. Meiner genedigsteñ || vnnd genedigen Herren Hertzog || Johans Friderichen Churfürsten zu Sachssen/|| etc. Vnnd Herren Philipsen Landgraffen zu || Hessen/ etc. warhafftige/ außfürung/das || Marggraue Hansen von Brandenburg || nit gebürt/ sich in der Key. Maiestat || dienst wider jr Chur vñ Fürstliche || gnad/ vnd ander derselben Re=||ligions verwandte einzu=||lassen/ noch darinn || zuuerharren.|| Sampt Bapst Pauli des drit=||ten Gottlos gifftig schreiben/ an gemei=||ne Aydgnossen/ welchs die falsch ver=||plömung dieses Kriegs gentz=||lich anzeigt.

Author

Paul <III., Papst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Katholische Kirche, Papst Paul III., Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Paul <III., Papst>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Katholische Kirche, Papst Paul III., Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Signaturformel: A-C4, Vorlageform des Erscheinungsvermerks: Anno M.D.XLVI.||[Erfurt: Melchior Sachse d.Ä.]

49. Voñ Gottes gnaden || Johannes Friderich/ Hertzog || zu Sachssen/ Philips Landt=||graff zu Hessen/ vnd gemeiner || Christlicher eynung ver=||ordnete Kriegs || Rethe.|| An Hertzog Wilhelm zu || Bayern/ 1546. den 3. Augusti.

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Vorlageform des Erscheinungsvermerks: [Erfurt: Melchior Sachse d.Ä. 1546]

50. Ausschreiben, an alle || Stende des Reichs, jnn der Christ-||lichen Religion ... || Die beschwerung des Keyserlichen Cam-||mergerichts belangende.|| ...

Author

Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, Philipp <I., Hessen, Landgraf>, Sachsen-ernestinische Linie, Kurfürst Johann Friedrich I., Hessen, Landgraf Philipp, Johann Friedrich <I., Sachsen, Kurfürst>, and Philipp <I., Hessen, Landgraf>

Abstract

Verfasser nicht auf der Haupttitelseite genannt., Vorlageform des Erscheinungsvermerks: (Gedruckt zu Straßburg bey Hans || Preüssen. M.D.xxxix.||)

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