110 results on '"Furkan Ufuk"'
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2. A Rare Cause of Giant Intrathoracic Mass in a Woman with Sickle Cell Disease: Extramedullary Hematopoiesis
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Furkan Ufuk, İclal Ocak, Lydia Chelala, and Luis Landeras
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sickle cell disease ,computed tomography ,extramedullary hematopoiesis ,chest ,Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2024
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3. Successful treatment of acute myocardial injury of Duchenne muscular dystrophy with steroids: a case report
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Merve Oğuz, Dolunay Gürses, Furkan Ufuk, Münevver Yılmaz, and Olcay Güngör
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Duchenne muscular dystrophy ,Acute chest pain ,Cardiac magnetic resonance imaging ,Corticosteroid ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background Duchenne muscular dystrophy (DMD) is an X-linked muscular disease which is caused by the absence of dystrophin. Troponin elevation with acute chest pain may indicate acute myocardial injury in these patients. We report a case of DMD that presented with ACP and troponin elevation, who was diagnosed with acute myocardial injury, and successfully treated with corticosteroids. Case presentation A 9-year-old with DMD was admitted to the emergency department with the complaint of acute chest pain. His electrocardiogram (ECG) revealed inferior ST elevation and serum troponin T was elevated. The transthoracic echocardiography (TTE) demonstrated inferolateral and anterolateral hypokinesia with depressed left ventricular function. An ECG-gated coronary computed tomography angiography ruled out acute coronary syndrome. Cardiac magnetic resonance imaging revealed mid-wall to sub-epicardial late gadolinium enhancement at the basal to the mid inferior lateral wall of the left ventricle and corresponding hyperintensity on T2-weighted imaging, consistent with acute myocarditis. A diagnosis of acute myocardial injury associated with DMD was made. He was treated with anticongestive therapy and 2 mg/kg/day of oral methylprednisolone. Chest pain resolved the next day, and ST-segment elevation returned to normal on the third day. Troponin T decreased in the sixth hour of oral methylprednisolone treatment. TTE on the fifth day revealed improved left ventricular function. Conclusion Despite advances in contemporary cardiopulmonary therapies, cardiomyopathy remains the leading cause of death in patients with DMD. Acute chest pain attacks with elevated troponin in patients with DMD without coronary artery disease may indicate acute myocardial injury. Recognition and appropriate treatment of acute myocardial injury episodes in DMD patients may delay the development of cardiomyopathy.
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- 2023
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4. Drug-induced lung disease: a brief update for radiologists
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Furkan Ufuk, Selen Bayraktaroğlu, and Ayşe Rüksan Ütebey
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computed tomography ,immunotherapy ,lung ,pneumonitis ,pulmonary toxicity ,therapy ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Pulmonary adverse events and drug-induced lung disease (DILD) can occur when treating many conditions. The incidence of DILDs in clinical practice and the variety of radiological findings have increased, mainly due to the increased use of novel therapeutic agents. It is crucial to determine whether the newly emerging clinical and imaging findings in these patients are due to the progression of the underlying disease, infection, pulmonary edema, or drug use, as this will change the patient management. Although the diagnosis of DILD is usually obtained by excluding other possible causes, radiologists should be aware of the imaging findings of DILD. This article reviews the essential radiological results of DILD and summarizes the critical clinical and imaging findings with an emphasis on novel therapeutic agents.
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- 2023
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5. Cross-sectional imaging findings of cardiac outpouchings
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Furkan Ufuk and Tuncay Hazirolan
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aneurysm ,cardiac catheterization ,computed topography angiography ,congenital heart disease ,coronary artery disease ,diagnosis ,diverticulum ,echocardiogram ,embolism ,magnetic resonance imaging ,outpouching ,pericardial ,pseudoaneurysm ,three-dimensional ,ventricles ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
A cardiac outpouching (CO) is a protrusion in a heart chamber’s internal anatomical lining. Most COs are clinically insignificant, but some are of vital importance, requiring immediate surgery. Cross-sectional imaging findings of COs, such as location, morphology, size, and accompanying wall motion abnormalities, play an essential role in determining the correct diagnosis and appropriate clinical management. Therefore, radiologists should be familiar with them. This article reviews the key cross-sectional imaging findings and differential diagnoses of COs.
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- 2023
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6. A Young Boy with Renal Agenesis and Ectopic Seminal Vesicle: Zinner Syndrome
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Ahmet Yasin Yitik, Furkan Ufuk, and Sinan Çelen
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imaging ,congenital malformations ,renal agenesis ,Surgery ,RD1-811 ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Zinner syndrome is a rare disorder, and it is associated with unilateral renal agenesis, ipsilateral ejaculatory duct atresia (obstruction), and cystic dilatation of the ipsilateral seminal vesicle. Here, we present an eighteen-year-old male with Zinner syndrome who presented to a urology clinic with perineal/pelvic pain and dysuria. We also emphasize the computed tomography and magnetic resonance imaging findings of Zinner syndrome.
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- 2023
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7. COVID-19 pneumonia: lessons learned, challenges, and preparing for the future
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Furkan Ufuk and Recep Savaş
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Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Coronavirus disease 2019 (COVID-19) is a viral disease that causes life-threatening health problems during acute illness, causing a pandemic and millions of deaths. Although computed tomography (CT) was used as a diagnostic tool for COVID-19 in the early period of the pandemic due to the inaccessibility or long duration of the polymerase chain reaction tests, current studies have revealed that CT scan should not be used to diagnose COVID-19. However, radiologic findings are vital in assessing pneumonia severity and investigating complications in patients with COVID-19. Long-term symptoms, also known as long COVID, in people recovering from COVID-19 affect patients’ quality of life and cause global health problems. Herein, we aimed to summarize the lessons learned in COVID-19 pneumonia, the challenges in diagnosing the disease and complications, and the prospects for future studies.
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- 2022
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8. A rare chest wall deformity: Intrathoracic rib
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Furkan Ufuk
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Pediatrics ,RJ1-570 - Published
- 2023
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9. A Bull’s Head Sign in SAPHO
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Firdevs Ulutaş, Furkan Ufuk, Aslı Bozdemir, and Veli Çobankara
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Synovitis ,Acne ,Pustulosis ,Hyperostosis ,Osteitis ,Medicine - Abstract
A syndrome of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) is a rare autoimmune disease. It occurs in genetically predisposed individuals by immune activation triggered by possible infectious agents. A 60-year-old man was presented with musculoskeletal and cutaneous manifestations. After exclusion of differential diagnoses, he was diagnosed with SAPHO and successfully treated with adalimumab. He had a typical image defined as a bull’s head sign in bone scintigraphy with 99mTc- methylene diphosphonate. Positron emission tomography also revealed increased inflammatory activity in related anterior chest joints and soft tissue. We want to emphasize diagnostic radiological images in patients with SAPHO to increase the awareness of clinicians.
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- 2023
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10. Premature atherosclerosis and acute coronary syndrome in a child with end-stage renal disease
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Tülay Becerir, Münevver Yılmaz, İlknur Girişgen, Neslihan Yılmaz, Dolunay Gürses, Furkan Ufuk, Gökay Nar, and Selçuk Yüksel
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Acute coronary syndrome ,End-stage renal disease ,Myocardial infarction ,Children ,Pediatrics ,RJ1-570 - Abstract
Abstract Background Although acute coronary syndrome is rare in children, it is the most important cause of mortality in children with end-stage renal disease. Case presentation Here, a 16-year-old pediatric patient, who has been on dialysis since the age of 3, and who was diagnosed with acute coronary syndrome and placed an emergency percutaneous transcatheter stent in the left anterior descending branch of the left coronary artery is presented. It is important that the present patient does not have any electrocardiography findings in favor of cardiovascular disease and that he cannot fully explain the complaint of chest pain due to his mental retardation. Conclusions Early detection of acute coronary syndrome is life-saving, especially in children with chronic kidney disease.
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- 2021
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11. Less known but important complications and associated anomalies of Abernethy malformation
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Ayşe Rüksan Ütebey, Furkan Ufuk, and Muhammed Raşid Aykota
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cirrhosis ,congenital ,diagnosis ,liver ,portal hypertension ,portal vein ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Published
- 2023
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12. Letter to the Editor: 'Prospective assessment of VI-RADS score in multiparametric MRI in bladder cancer: accuracy and the factors affecting the results'
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Furkan Ufuk and Ahmet Baki Yağcı
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bladder ,cancer ,invasive ,magnetic resonance imaging ,tumor ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Published
- 2023
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13. Pulmonary embolism initially misdiagnosed as perimyocarditis in a young patıent
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Oguz Kilic, Alperen E Akgun, Furkan Ufuk, Ipek Buber, and Ismail D Kilic
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electrocardiography ,pericarditis ,pulmonary embolism ,st elevation ,troponin ,Anesthesiology ,RD78.3-87.3 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Pulmonary embolism is a common cardiovascular emergency. In case of delayed diagnosis and treatment morbidity and mortality is high. In this report, we presented a case of pulmonary embolism without apparent risk factors, which was initially misdiagnosed as peri/myocarditis.
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- 2022
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14. Evaluation of disease severity with quantitative chest CT in COVID-19 patients
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Furkan Ufuk, Mahmut Demirci, Erhan Uğurlu, Nazlı Çetin, Nilüfer Yiğit, and Tuğba Sarı
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Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
PURPOSEWe aimed to assess the severity of coronavirus disease 2019 (COVID-19) pneumonia on computed tomography (CT) using quantitative (QCT) and semiquantitative (SCT) assessments and compare with the clinical findings.METHODSTwo observers independently examined the CT images of COVID-19 patients, and the SCT severity score was calculated. The SCT score was calculated as the sum of values ranging from 0 to 4, according to the volumetric rate of involvement for each lung lobe. In quantitative assessment, total lung volume (TLV) was automatically calculated from CT density values between -200 and -950 HU. Besides, healthy lung volume (HLV) was calculated from voxels between -800 and -950 HU. The QCT score was calculated with the following formula: (TLV – HLV / TLV) ×100. All patients were clinically divided into four groups: mild, common, severe, and critical. Interobserver agreement for SCT assessment was investigated using the Cohen's Kappa statistics (κ). Pearson's correlation coefficient was used for the relationship between continuous data. The diagnostic accuracy of SCT and QCT in the differentiation of clinically limited (mild, common) and extensive (severe, critical) disease was investigated using ROC analysis.RESULTSSeventy-six patients with a diagnosis of COVID-19 were included. There was good agreement between the two observers in the SCT evaluation of pulmonary disease severity (κ = 0.796; 95% CI, 0.751–0.841). A significant correlation was found between QCT and SCT scores (p < 0.001, r = 0.661). Both QCT and SCT scores showed a significant correlation with clinical severity score (p < 0.001, r = 0.620 and p = 0.004, r = 0.529, respectively). The ROC analysis revealed the AUC of QCT and SCT for differentiation of limited and extensive disease as 0.873 (95% CI, 0.774–0.972) and 0.816 (95% CI, 0.673–0.959), respectively.CONCLUSIONThe QCT assessment is an objective method in the evaluation of COVID-19 severity and is more successful than semiquantitative CT assessment to discriminate extensive from limited disease.
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- 2021
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15. An Unusual Cause of Rectal Pressure and Difficult Defecation: Giant Pelvic Myelolipoma
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Burak Sarılar, Hüseyin Gökhan Yavaş, and Furkan Ufuk
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magnetic resonance imaging ,computed tomography ,pelvis ,myelolipoma ,lipomatous tumour ,Specialties of internal medicine ,RC581-951 - Abstract
Myelolipoma is a rare benign neoplasm consisting of mature adipose and haematopoietic tissues and usually found in the adrenal gland. However, myelolipoma can be rarely detected in extra-adrenal regions but often detected incidentally in imaging studies performed for other reasons or at autopsy. While adrenal myelolipomas are easily recognised given its typical imaging features, the diagnosis of extra-adrenal myelolipomas may be challenging. Herein, we aimed to present computed tomography and magnetic resonance imaging findings of pelvic extra-adrenal myelolipoma in a 77-year-old woman with hepatocellular carcinoma and to describe the differential diagnoses.
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- 2021
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16. Letter to the Editor: Indeterminate pulmonary subsolid nodules in patients with no history of cancer
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Furkan Ufuk
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computed tomography ,diagnosis ,lung ,neoplasm ,nodule ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Published
- 2023
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17. Questions about 'Intra-atrial right coronary artery on dual-source CT'
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Furkan Ufuk
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cardiology ,coronary artery ,coronary artery disease ,ct angiography ,diagnosis ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Published
- 2023
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18. Diagnosis of Sarcopenia in Head and Neck Computed Tomography: Cervical Muscle Mass as a Strong Indicator of Sarcopenia
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Furkan Ufuk, Duygu Herek, and Doğangün Yüksel
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Sarcopenia ,Computed Tomography ,Head and Neck Neoplasms ,Computer-Assisted Image Analysis ,Body Mass Index ,Medicine ,Otorhinolaryngology ,RF1-547 - Abstract
Objectives Patients with head and neck cancer (HNC) have a high risk of sarcopenia, which is associated with poor prognosis. Skeletal-muscle area and index at the third lumbar (L3) vertebra level (L3MA and L3MI) are recommended for the detection of sarcopenia. However, L3 level is not included in many imaging protocols and there are no data for optimal levels and cutoffs for the diagnosis of sarcopenia in head and neck computed tomography (HNCT) scans. Our aim was to assess the relationship between cervical paravertebral muscle values and L3MI and to investigate optimal level to diagnose sarcopenia on HNCTs. Methods Patients with HNC (n=159) who underwent positron emission tomography-CT for tumor staging were retrospectively analyzed. On CT images, paravertebral and sternocleidomastoid muscle areas at second (C2), third (C3), and fourth (C4) cervical vertebrae levels (C2MA, C3MA, C4MA, SCMA) and L3MA were measured. Cross-sectional areas were normalized for stature (muscle area/height square) and muscle index (C2MI, C3MI, C4MI, SCMI, L3MI) values were obtained. Spearman correlation and linear regression analyses were used for assessing correlations. To calculate the diagnostic performance of SCMI, C2MI, C3MI, and C4MI for the diagnosis of sarcopenia with respect to the cutoffs of L3MI, receiver operating characteristic (ROC) analysis was used. Results Males had significantly higher muscle areas than females. Although C2MI, C3MI, C4MI, and SCMI values all showed very strong and significant correlation with L3MI (P
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- 2019
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19. Corticosteroid-induced Knee Osteonecrosis and Accompanying Femoral Head Osteonecrosis
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Nuran Sabir and Furkan Ufuk
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Magnetic resonance imaging ,plain radiography ,osteonecrosis ,corticosteroid ,knee ,hip ,Medicine - Abstract
Introduction:The aim of this study was to investigate the prevalence and magnetic resonance imaging (MRI) findings of knee osteonecrosis (ON) in patients with arthralgia who received corticosteroid therapy. We also aimed to demonstrate the diagnostic performance of plain radiography in knee ON when MRI is accepted as the gold standard and to investigate the prevalence of accompanying femoral head ON in patients who underwent hip MRI.Methods:One hundred and sixty-two knee X-rays and MRI examinations of 136 patients with knee pain and a history of corticosteroid intake were retrospectively evaluated for the presence of ON. Localization, maximum size of dominant lesion, multiplicity of lesions, presence of bone edema, double-line sign and subchondral extension were evaluated in patients with ON. Accompanying femoral head ON was also investigated in patients who underwent hip MRI.Results:MRI revealed ON in 37 knees of 28 patients. The sensitivity and specificity of plain radiography in the diagnosis of knee joint ON was 29.73% and 98.40%, respectively. There were multiple lesions in 31 knees and subchondral space was affected in 24 knees. The double-line sign and bone marrow edema were present in most of the lesions. Of the 28 patients with knee ON, only 16 had hip joint MRI and five of these patients (31.3%) had femoral head ON.Conclusion:Plain radiography has low sensitivity but high specificity for the diagnosis of knee ON. Corticosteroid-induced ON tends to be multifocal, and a significant proportion of patients with knee ON during corticosteroid therapy have ON of the hip joint.
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- 2019
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20. Extra-Parenchymal Chest HRCT Findings in Patients with Systemic Sclerosis at the Time of Initial Diagnosis
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Furkan UFUK, Pinar CAKMAK, Ergin SAGTAS, Veli COBANKARA, and Baki YAGCI
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Systemic sclerosis ,scleroderma ,high-resolution computed tomography ,thymus ,lymph node ,Medicine (General) ,R5-920 - Abstract
Objective:In systemic sclerosis (SS) patients who are receiving treatment, findings of extra-parenchymal chest involvement (such as thymic abnormality, mediastinal lymph node enlargement) have been previously examined. However, these findings may be affected by medical treatment. Our aim was to evaluate the extra-parenchymal chest high-resolution computed tomography (HRCT) findings of patients with SS at the time of initial diagnosis. Methods:We retrospectively analyzed medical database of patients with SS. Chest HRCT images within 1 month after initial diagnosis of these patients were re-evaluated for the presence of distal esophageal dilatation, thymic hyperplasia, mediastinal lymph node enlargement, pleural or pericardial abnormalities (effusion or thickening). Intergroup comparisons were performed using independent t-test or a Mann-Whitney U test. To detect the relationship between continuous variables, Spearman’s correlation coefficients and univariate correlations were used.Results:A total of 51 patients (45 women and 6 men, mean age + STD; 49.2 years+13.9) with SS were included in the study. Esophageal dilatation (88.2%) was the most common finding. Six patients (11.8%) had thymic enlargement. Mediastinal lymph node enlargement (11.8%) and pleural abnormalities (11.8%) were significantly more common in patients with SS diagnosed at late age (p
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- 2019
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21. Diaphragm Thickness Measurement in Computed Tomography: Intra- and Inter-Observer Agreement
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Furkan Ufuk, Pınar Çakmak, Ergin Sağtaş, Duygu Herek, Muhammet Arslan, and Ahmet Baki Yağcı
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Computed tomography ,diaphragm thickness ,measurement ,reliability ,Medicine - Abstract
Introduction:Diaphragm thickness (DT) measurement in computed tomography (CT) has become popular in recent years. Our aim was to assess the intra- and inter-observer agreement of DT measurement and to investigate the best points for DT assessment in CT based on the most reliable measurement.Methods:Thoraco-abdominal CT angiography scans of 44 patients (23 males, mean age: 49.9±17.8 years) were retrospectively evaluated. All of the CT images were evaluated independently by four radiologists. Each observer evaluated images twice to assess intra-observer reproducibility. On both axial and coronal reconstructed CT images, the crura of 88 hemidiaphragms were measured at five different points. A p value less than 0.05 was considered to indicate statistical significance. Intra- and inter-observer agreement was evaluated by using intraclass correlation coefficient (ICC) scores with a 95% confidence interval.Results:In intra-observer analysis, ICC scores demonstrated substantial to almost perfect agreement for all measurements (ICC score range: 0.758-1). When we analyzed the inter-observer agreement, there was a moderate to almost perfect agreement for each measurement point (ICC score range: 0.523-0.895). All axial measurements showed the highest inter-observer agreement (ICC scores were 0.926 and 0.886 for first and second measurements, respectively). The maximum inter- and intra-observer agreement for single point DT measurements were found in maximum DT at the level of the origin of the celiac artery and in anterior DT at the level of the upper part of the L1 vertebral body.Conclusion:CT is a reliable tool DT measurement with excellent intra- and inter-observer agreement.
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- 2019
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22. Tracheobronchial Angle Measurements in Children: An Anthropometric Retrospective Study With Multislice Computed Tomography
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Duygu Herek, Ozkan Herek, and Furkan Ufuk
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Trachea ,Spiral Computed Tomography ,Thorax ,Child ,Medicine ,Otorhinolaryngology ,RF1-547 - Abstract
Objectives The purpose of this study is to investigate if any change exists in the values of tracheal bifurcation angles (subcarinal angle [SCA] and interbronchial angle [IBA]), right and left bronchial angles (RBA and LBA) in different pediatric age groups. Methods Chest computed tomography (CT) images of children aged 18 years and younger were reviewed retrospectively by two radiologists who were blinded to each other’s measurements. One hundred and eighteen children were involved. RBA, LBA, SCA, and IBA were measured on coronal reformatted images. Subjects were classified into three groups according to their age. Measurement of IBA was done by measuring the angle between the lines drawn along the central axis of right and left main bronchi over their length. RBA and LBA were measured at the intersection points of the lines drawn along the inferior borders of the right and left main bronchi and the line passing through the longitudinal axis of trachea. Sums of RBA and LBA gave SCA. Interobserver agreement was also analyzed. Results SCA, IBA, and RBA values were statistically significant between children of ages less than 10 years and over 10 years P
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- 2017
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23. Anomalous origin of the right coronary artery from the pulmonary artery and simultaneous coronary-bronchial artery fistula
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Furkan Ufuk, Oğuz Kılıç, and Ismail Dogu Kılıç
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anomalous origin of the right coronary artery from pulmonary artery ,computed tomography angiography ,coronary angiography ,arterio-arterial fistula ,pulmonary artery. ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2020
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24. CT evaluation of medial clavicular epiphysis as a method of bone age determination in adolescents and young adults
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Furkan Ufuk, Kadir Agladioglu, and Nevzat Karabulut
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Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
PURPOSEWe aimed to investigate the use of computed tomography (CT) staging of the medial clavicular epiphysis ossification in forensic bone age determination, and find a CT criterion to determine whether an individual is adult or not.METHODSChest CT and pulmonary CT angiography exams of 354 patients between 10 and 30 years of age (mean, 21.4 years) were retrospectively evaluated for epiphyseal ossification phase of the bilateral medial clavicles (708 clavicles) and compared with the sex and chronologic age of the individuals. The ossification phase of the medial clavicular epiphyses was classified from stage I to stage V using a modified staging system.RESULTSEpiphyseal ossification center appeared from 11 to 21 years of age. Partial fusion occurred between 16 and 23 years of age. Complete fusion was first achieved at the ages of 18 and 19 years for male and female individuals, respectively. The probability of an individual being ≥18 years old was 70.8% in stage III A and 100% in stages III B, IV, and V in females and males. CONCLUSIONCT evaluation of the medial clavicular epiphysis is helpful in forensic age determination and stage III B can be used as a criterion to make the prediction that an individual is older than 18 years.
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- 2016
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25. Radiological approach to COVID-19 pneumonia: attention should be paid to pulmonary embolism and radiation exposure
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Furkan Ufuk
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Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Published
- 2020
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26. Acute Myeloid Leukemia with Hypothalamic Involvement Causing Central Diabetes Insipidus
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Furkan Ufuk, Mehmet Duran, and Mehmet Sercan
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Acute myeloid leukemia ,hypothalamus ,magnetic resonance imaging ,central diabetes insipidus ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2018
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27. Nadir Bir İnce Barsak Obstrüksiyon Nedeni: Paraçekal İnternal Herni
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Muhammet Gündüz, Furkan Ufuk, Muhammet Raşid Aykota, and Cihan Kaya
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computed tomography ,internal hernia ,bowel obstruction ,bilgisayarlı tomografi ,i̇nternal herni ,barsak obstrüksiyonu ,Medicine - Abstract
İnternal herni, nadir görülen intestinal obstrüksiyon nedenidir. Hastalarda karın ağrısı, bulantı ve kusma gibi semptomlar bulunabilir. İnternal herni tanısı sıklıkla atlanmakta olup,yüksek mortalitesi nedeniyle intestinal obstrüksiyon bulgularıyla başvuran hastalarda internal herninin araştırılması, erken tanı ve tedavi büyük önem taşımaktadır. Biz buradaperiçekal internal hernisi bulunan bir olgu sunarak, bilgisayarlı tomografinin (BT) tanıdaki rolünü değerlendirdik.
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- 2017
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28. A case of thromboembolic events as first manifestation of membranous nephropathy
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Almıla ÜYÜK, Murat Yaşar TAŞ, Belda DURSUN, and Furkan UFUK
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Medicine ,General Earth and Planetary Sciences ,Hipoalbüminemi ,Nefrotik Sendrom ,Proteinüri ,tromboembolizm ,Hypoalbuminemia ,Nephrotic Syndrome ,Proteinuria ,Thromboembolism ,Tıp ,General Environmental Science - Abstract
We present a case of idiopathic membranous glomerulonephritis that presented with venous thromboembolism and was successfully managed with corticosteroid, cyclosporin, appropriate anticoagulant therapy. A 59-year old male patient was referred to our nephrology department who had an outpatient history of swelling in the feet and flank pain was detected proteinuria and thrombosis in the inferior vena cava. Warfarin sodium treatment was started when thrombus was detected in the femoral vein, renal vein and inferior vena cava in the imaging. The patient had 12 g/day proteinuria, hypoalbuminemia, hyperlipidemia and antiphospholipase A2 receptor antibody positivity and treatment was started with the diagnosis of idiopathic membranous nephropathy. The patient who was discharged with oral steroid, cyclosporine and warfarin sodium, but warfarin sodium was changed to rivaroxaban in another clinic due to incompatibility problems, was presented again with dsypnea. Pulmonary embolism was detected. Rivaroxaban was discontinued and low molecular weight heparin treatment was started. There was a very high risk of morbidity and mortality and with appropriate treatment, clinical status and renal function were stabilized. In conclusion, although thromboembolism can be seen in nephrotic syndrome, it may rarely be encountered as the first presentation of nephrotic syndrome. This situation should not be overlooked, appropriate treatments should be provided without delay., Venöz tromboembolizm ile prezente olan ve kortikosteroid, siklosporin, uygun antikoagülan tedavi ile başarılı bir şekilde tedavi edilen bir idiyopatik membranöz glomerülonefrit olgusu sunuyoruz. Ayaklarda şişlik, yan ağrısı şikayetleri olan 59 yaşında erkek hastada proteinüri ve vena cava inferiorda tromboz tespit edilmesi sonucu nefroloji bölümümüze sevk edildi. Görüntülemede femoral ven, renal ven ve inferior vena cavada trombüs saptanması üzerine varfarin sodyum tedavisi başlandı. 12 g/gün proteinüri, hipoalbüminemi, hiperlipidemi ve anti fosfolipaz A2 reseptör antikor pozitifliği saptanan hastaya idiyopatik membranöz nefropati tanısı ile tedavi başlandı. Oral steroid, siklosporin ve varfarin sodyum ile taburcu edilen ancak uyumsuzluk nedeniyle başka bir klinikte varfarin sodyum rivaroksaban ile değiştirilen hasta nefes darlığı şikayeti ile tekrar başvurdu. Pulmoner emboli tespit edilmesi üzerine rivaroksaban kesildi ve düşük molekül ağırlıklı heparin tedavisi başlandı. Çok yüksek bir morbidite ve mortalite riski vardı ve uygun tedavi ile klinik durum ve böbrek fonksiyonu stabilize edildi. Sonuç olarak, nefrotik sendromda tromboemboli görülebilmesine rağmen, nefrotik sendromun ilk prezentasyonu olarak nadiren de olsa tromboemboli ile karşılaşılabilinir. Bu durum gözden kaçırılmamalı, uygun tedaviler geciktirilmeden sağlanmalıdır.
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- 2022
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29. The Role and Limitations of Large Language Models Such as ChatGPT in Clinical Settings and Medical Journalism
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Furkan Ufuk
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Radiology, Nuclear Medicine and imaging - Published
- 2023
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30. Toxoplasmosis: A Significant Parasitic Zoonosis
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Furkan Ufuk
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Radiology, Nuclear Medicine and imaging - Published
- 2023
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31. Case 315
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Furkan Ufuk and Ismail Dogu Kilic
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Radiology, Nuclear Medicine and imaging - Published
- 2023
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32. Course Effectiveness in Recreation Undergraduate Programs: Descriptive Research
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Kerem Yıldırım ŞİMŞEK, Deniz Raha KOLOĞLU, and Furkan Ufuk YILDIZ
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- 2022
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33. Swyer-James-MacLeod Syndrome in a Patient With Eisenmenger Syndrome
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Dolunay Gürses, Merve Oğuz, Doğangün Yüksel, Furkan Ufuk, and Münevver Yılmaz
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Swyer-James-MacLeod syndrome is a condition characterized radiologically by hyperlucency in a single lung lobe associated with reduced vascularity, alveolar hyperdistention, and air trapping in the absence of bronchial airway obstruction. Ventricular septal defect is the most common congenital heart defect in childhood and causes irreversible pulmonary hypertension and Eisenmenger syndrome if not treated in a timely manner. In this case report, we present a 25-year-old patient with Swyer-James-MacLeod syndrome and Eisenmenger syndrome. Including Swyer-James-MacLeod syndrome in the differential diagnosis of patients with atypically distributed pulmonary emphysema and unilateral hyperlucency is important for early diagnosis and timely treatment.
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- 2022
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34. Pulmonary embolism initially misdiagnosed as perimyocarditis in a young patıent
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IsmailD Kilic, Oguz Kilic, AlperenE Akgun, Furkan Ufuk, and Ipek Buber
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leukocyte count ,pulmonary embolism ,electrocardiography ,5,10 methylenetetrahydrofolate reductase (FADH2) ,genetic analysis ,diagnostic error ,st elevation ,physical examination ,pericarditis ,colchicine ,Article ,cardiovascular magnetic resonance ,angina pectoris ,male ,Anesthesiology ,nonsteroid antiinflammatory agent ,case report ,echocardiography ,follow up ,Humans ,Diseases of the circulatory (Cardiovascular) system ,dabigatran ,RD78.3-87.3 ,gene mutation ,human ,Diagnostic Errors ,gene ,inspiratory capacity ,computed tomographic angiography ,clinical article ,MTHFR gene ,troponin ,low molecular weight heparin ,adult ,ST segment elevation ,General Medicine ,myopericarditis ,hospital discharge ,hospital admission ,Myocarditis ,Anesthesiology and Pain Medicine ,risk factor ,upper respiratory tract infection ,drug withdrawal ,RC666-701 ,young adult ,Cardiology and Cardiovascular Medicine ,lung embolism - Abstract
Pulmonary embolism is a common cardiovascular emergency. In case of delayed diagnosis and treatment morbidity and mortality is high. In this report, we presented a case of pulmonary embolism without apparent risk factors, which was initially misdiagnosed as peri/myocarditis. © 2022 Annals of Cardiac Anaesthesia.
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- 2022
35. Case 289: PIK3CA-related Overgrowth Spectrum (PROS): CLOVES Syndrome and Coexisting Fibroadipose Vascular Anomaly
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Furkan Ufuk
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medicine.medical_specialty ,business.industry ,Left thigh ,Medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,business ,medicine.disease ,CLOVES syndrome ,Vascular anomaly - Abstract
History Part one of this case appeared 4 months previously and may contain larger images. An 8-year-old girl presented to our hospital with painful swelling of the left thigh and soft-tissue swelli...
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- 2021
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36. Successful Implantation of Two Stents in the Right Coronary Artery in a Patient with a Single Coronary Artery Anomaly
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Furkan Ufuk, Musa Sanlialp, Sara Cetin Sanlialp, Ömer Çağliyan, and Gökay Nar
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Internal medicine ,Right coronary artery ,medicine.artery ,Single coronary artery ,medicine ,Cardiology ,Percutaneous coronary intervention ,Anomaly (physics) ,business - Abstract
Single coronary artery is a congenital cardiac anomaly in which the right coronary artery or left main coronary artery arises from a single aortic ostium. This coronary anomaly is rare and may lead to a wide range of clinical manifestations from asymptomatic to sudden cardiac death, depending on its association with great vessels. In addition, proven treatment strategies for this anomaly have not yet been established. In this report; we presented a single coronary artery originating from the right sinus of valsalva, and successful two stents implantation of the middle and distal right coronary artery in a patient with acute coronary syndrome.
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- 2021
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37. Management of Patients with Connective Tissue Disease-associated Interstitial Lung Diseases During the COVID-19 Pandemic
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Canan Gündüz Gürkan, Goksel Altinisik, Dilek Karadoğan, Furkan Ufuk, Osman Cure, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, and Karadoğan, Dilek
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medicine.medical_specialty ,Lung ,Isolation (health care) ,business.industry ,SARS-CoV-2 ,Outbreak ,Disease ,Review ,Lung imaging ,medicine.disease ,Connective tissue disease ,Management ,medicine.anatomical_structure ,Rheumatic diseases ,Pandemic ,Medicine ,Medical history ,Differential diagnosis ,business ,Intensive care medicine ,Radiology - Abstract
The novel coronavirus disease (COVID-19) is similar to connective tissue disease-associated interstitial lung diseases (CTD-ILD) in many aspects. However, patients with CTD-ILD have required particular attention during the pandemic since they are at high risk due to immunosuppressive treatments. Thus, prompt decisions for diagnosis and treatment initiation have become more important than earlier for these patients during the pandemic. Radiological perspectives have become inevitable for the differential diagnosis of this group during the pandemic, particularly to obtain rapid and accurate results that allow the physicians to start treatment immediately. However, in addition to radiological images, a definitive diagnosis also requires access to extensive information regarding patient history, including characteristics of comorbidities, and clinical and serological findings. Consequently, the differential diagnosis of COVID-19 and CTD-ILD can yield accurate treatment regimens that differ greatly between the 2 diseases, and also prevent the spread of the outbreak with COVID-19 patients treated under isolation. © 2021, AVES. All rights reserved.
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- 2022
38. A rare cause of severe dyspnea and right upper quadrant pain: Tension hydrothorax
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Furkan Ufuk
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- 2022
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39. Endotracheal Metastasis of Colon Cancer Presenting As Severe Dyspnea
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Furkan Ufuk
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- 2022
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40. Comparison of 68Ga-PSMA-I/T PET-CT and Multiparametric MRI for Locoregional Staging of Prostate Cancer Patients: A Pilot Study
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Aziz Gültekin, Sinan Çelen, Ali Ersin Zumrutbas, Doğangün Yüksel, Ergin Sagtas, Furkan Ufuk, Baki Yagci, Yusuf Özlülerden, and Aslı Mete
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PET-CT ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Prostatectomy ,Urology ,medicine.medical_treatment ,Multiparametric MRI ,urologic and male genital diseases ,medicine.disease ,Neck of urinary bladder ,Prostate cancer ,Positron emission tomography ,Medicine ,Histopathology ,business ,Nuclear medicine ,Multiparametric Magnetic Resonance Imaging - Abstract
Background/Aim: The objective of this work was to assess the value of 68Ga-DOTAGA-(3-iodo-y)fk(Sub-KuE) positron emission tomography (68Ga-PSMA-I/T PET-CT) and multiparametric magnetic resonance imaging (mp-MRI) for preoperative staging in prostate cancer (PCa) patients who underwent radical prostatectomy (RP) by validating with postoperative histopathology data. Materials and Methods: We prospectively investigated 30 consecutive PCa patients who had both mp-MRI and 68Ga-PSMA-I/T PET-CT before laparoscopic RP. The seminal vesicle invasion (SVI), lymph node metastasis (LNM), bladder neck invasion (BNI), and extracapsular extension (ECE) were investigated separately. The diagnostic performances of mp-MRI and 68Ga-PSMA-I/T PET-CT were assessed using histopathological results. Results: Both mp-MRI and 68Ga-PSMA-I/T PET-CT were not statistically significant in the evaluation of SVI, BNI, and ECE preoperatively but had statistically significant results in the assessment of LNM. mp-MRI had higher overall sensitivity for ECE, overall specificity for SVI, ECE, and BNI, and positive predictive value for ECE, SVI, BNI. 68Ga-PSMA-I/T PET-CT had higher overall sensitivity for BNI, and negative predictive value for BNI and LNM. Conclusion: mp-MRI has superior specificity, sensitivity, and accuracy for assessing ECE and SVI. Both imaging modalities had similar specificity, sensitivity, and accuracy for determining BNI. However, both imaging modalities had low diagnostic accuracy for LNM on histopathology.
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- 2020
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41. Corticosteroid-induced Knee Osteonecrosis and Accompanying Femoral Head Osteonecrosis
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Furkan Ufuk and Nuran Sabir
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musculoskeletal diseases ,medicine.medical_specialty ,corticosteroid ,hip ,medicine.drug_class ,business.industry ,osteonecrosis ,lcsh:R ,knee ,lcsh:Medicine ,Surgery ,Magnetic resonance imaging ,plain radiography ,medicine ,Femoral head osteonecrosis ,Corticosteroid ,business - Abstract
Introduction: The aim of this study was to investigate the prevalence and magnetic resonance imaging (MRI) findings of knee osteonecrosis (ON) in patients with arthralgia who received corticosteroid therapy. We also aimed to demonstrate the diagnostic performance of plain radiography in knee ON when MRI is accepted as the gold standard and to investigate the prevalence of accompanying femoral head ON in patients who underwent hip MRI., Methods: One hundred and sixty-two knee X-rays and MRI examinations of 136 patients with knee pain and a history of corticosteroid intake were retrospectively evaluated for the presence of ON. Localization, maximum size of dominant lesion, multiplicity of lesions, presence of bone edema, double-line sign and subchondral extension were evaluated in patients with ON. Accompanying femoral head ON was also investigated in patients who underwent hip MRI., Results: MRI revealed ON in 37 knees of 28 patients. The sensitivity and specificity of plain radiography in the diagnosis of knee joint ON was 29.73% and 98.40%, respectively. There were multiple lesions in 31 knees and subchondral space was affected in 24 knees. The double-line sign and bone marrow edema were present in most of the lesions. Of the 28 patients with knee ON, only 16 had hip joint MRI and five of these patients (31.3%) had femoral head ON., Conclusion: Plain radiography has low sensitivity but high specificity for the diagnosis of knee ON. Corticosteroid-induced ON tends to be multifocal, and a significant proportion of patients with knee ON during corticosteroid therapy have ON of the hip joint.
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- 2019
42. Case 289
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Furkan, Ufuk
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Diagnosis, Differential ,Class I Phosphatidylinositol 3-Kinases ,Vascular Malformations ,Contrast Media ,Humans ,Female ,Lipoma ,Syndrome ,Child ,Nevus ,Musculoskeletal Abnormalities - Abstract
Part one of this case appeared 4 months previously and may contain larger images. An 8-year-old girl presented to our hospital with painful swelling of the left thigh and soft-tissue swelling in the right chest wall. The patient's history revealed that the swelling had been present since birth but had grown slowly. She had no history of relevant trauma. Her blood pressure was 145/95 mmHg (normal value,115/76 mmHg), and her heart rate was 105 beats per minute (normal value, 75-118 beats per minute). The patient's electrocardiogram displayed sinus tachycardia. Physical examination revealed soft-tissue hypertrophy in the left thigh and right lower chest wall. A painful soft and flexible mass measuring approximately 5 × 6 × 15 cm (in the anteroposterior, transverse, and craniocaudal directions, respectively) was detected at the left thigh. Moreover, a painless soft mass measuring approximately 3 × 8 × 10 cm (in the anteroposterior, transverse, and craniocaudal directions, respectively) was detected in the right lower chest wall, and the overlying skin was intact. Pink macules with a 3-cm diameter on the anterior left superior thigh and a 2.5-cm diameter in the left inguinal region were detected. Examination of other systems, including the cardiovascular system, revealed normal findings. Laboratory test results were within normal limits. Abdominal US showed perirenal vascular collaterals, and musculoskeletal US of the left thigh revealed vascular collaterals (images not shown). Therefore, thoracoabdominal CT angiography and contrast material-enhanced MRI of the bilateral thigh were performed.
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- 2021
43. Retrospective comparison of the sociodemographic, clinical, radiological and laboratory findings of probable and definitive COVID-19 cases
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Furkan Ufuk, Sevin Başer Öncel, Göksel Altinişik Ergur, Ahmet Çalişkan, Nazlı Çetin, Sibel Pekcan, Hüseyin Gökhan Yavaş, Seçim Kolak, Erhan Ugurlu, Nilüfer Yiğit, and Neşe Dursunoğlu
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medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,010102 general mathematics ,01 natural sciences ,03 medical and health sciences ,0302 clinical medicine ,Infectious Diseases ,CO-RADS,Probable COVID-19,RT-PCR,SARS-CoV-2 ,Internal medicine ,Radiological weapon ,Medicine ,030212 general & internal medicine ,0101 mathematics ,Enfeksiyon Hastalıkları ,business ,CO-RADS,Olası COVID-19,RT-PCR,SARS-CoV-2 ,General Environmental Science - Abstract
Amaç: Kliniğimizde takip edilen kesin COVID-19 vakalar ile olası COVID-19 vakalar arasındaki sosyodemografik, klinik, BT ve laboratuvar bulgularının farklarını incelemeyi amaçladık.Gereç ve yöntem: İlk vaka tarihi olan 13 Mart 2020 ile 5 Mayıs 2020 arasında, olası ve kesin COVID-19 tanısıyla Göğüs Hastalıkları servisinde yatan tüm hastaların verileri retrospektif olarak incelendi. Hastaların toraks BT bulguları, hastaların klinik ve PCR test sonuçlarına körleştirilen iki farklı radyolog tarafından CO-RADS sınıflamasına göre ayrı ayrı yorumlandı ve daha sonra ortak değerlendirme ile konsensüs sağlandı. Klinik, laboratuvar ve görüntüleme bulguları ile çoklu regresyon modellemesi yapıldı. Bulgular: Çalışmaya 38 RT-PCR pozitif, 62 RT-PCR negatif olmak üzere toplam 99 hasta dahil edildi. Nötrofil/lenfosit oranı (NLR) ve lenfosit sayısı, RT-PCR pozitif hastalarda istatistiksel olarak anlamlı düzeyde daha düşüktü (sırasıyla p = 0.038, p = 0.041). Benzer şekilde, pozitif hastalarda CRP değerlerinin istatistiksel olarak anlamlı düzeyde düşük olduğu gözlendi (p = 0.029). RT-PCR (+) ile RT-PCR (-) ancak toraks BT ‘si CO-RADS evrelemesine göre pozitif olan hastaların karşılaştırmalarında, RT-PCR (-) ancak toraks BT pozitif olan grupta anlamlı şekilde WBC, LDH ve CRP değerlerinin daha yüksek olduğu görüldü (sırasıyla p=0.001, p=0.033, p=0.004). Öksürük, WBC, LDH, CRP değerleri ve toraks BT skoru kullanılarak geliştirilen modelde en yüksek AUC değeri elde edilmiş, RT-PCR pozitifliğini ayırt etmede başarılı olabileceği görüldü (AUC=0.725, 95% CI: 0.619-0.830)Sonuç: Klinik bulgular varlığında RT-PCR pozitifliğini beklemeden COVID-19 uyumlu BT bulguları (CO-RADS'ye göre evre 4-5) ile yüksek WBC, CRP VE LDH varsa COVID-19 olasılığı artacaktır., Purpose: We aimed to determine the number of possible and precise cases among the patients hospitalized in our clinic and to examine the differences between the sociodemographic, clinical, chest CT and laboratory findings of these two groups.Materials and methods: The data of all patients hospitalized at the department of pulmonology service between March 13 as the date of the first case and May 5 with probable and definitive COVID-19 were evaluated retrospectively. Patient ward files and hospital data management system were examined. Chest CT findings of the patients were interpreted by two radiologists separately according to the CO-RADS classification blinded to clinical and PCR test results of the patients and then consensus was achieved with joint evaluation.Results: A total of 99 patients, 38 RT-PCR positive, 61 RT-PCR negative, were included in the study. Neutrophil-to-lymphocyte ratio(NLR) values and lymphocyte count were lower at a statistically significant level in positive patients(respectively p=0.038, p=0.041). Similarly, CRP values were observed to be lower at a statistically significant level in positive patients(p=0.029). When the patients with RT-PCR(+) and RT-PCR(-) but with positive chest CT findings according to CO-RADS staging were compared, the values of WBC, LDH and CRP level was observed to be high were statistically significant in the group with RT-PCR(-) but positive chest CT findings.Conclusion: In the presence of clinical findings, without waiting for RT-PCR positivity, the probability of COVID-19 disease will increase if there are elevated WBC, CRP and LDH findings with CT findings(stage 4-5 according to CO-RADS).
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- 2021
44. COVID-19-associated pancytopenia and typhlitis
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Furkan Ufuk, Tugba Sari, and Emre Bulgurcu
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Abdominal pain ,medicine.medical_specialty ,Pancytopenia ,Gastroenterology ,Article ,03 medical and health sciences ,Cecum ,0302 clinical medicine ,Internal medicine ,medicine ,Ascending colon ,Respiratory system ,Computed tomography ,Enterocolitis ,business.industry ,Neutropenic enterocolitis ,COVID-19 ,030208 emergency & critical care medicine ,General Medicine ,Pneumonia ,medicine.disease ,medicine.anatomical_structure ,Emergency Medicine ,medicine.symptom ,business - Abstract
Neutropenic enterocolitis is also known as typhlitis, is characterized by severe inflammation in the bowel loops. It is often seen in immunosuppressed patients, and it has high morbidity and mortality. Although the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory systemand causes COVID-19 (Coronavirus Disease 2019), it may affect hematopoietic and gastrointestinal systems. Herein, we present a rare case of COVID-19-associated pancytopenia and typhlitis in a 60-year-old female who presented with abdominal pain. Contrast-enhanced abdominal computed tomography (CT) demonstrated the bowel wall thickening in the cecum and ascending colon compatible with enterocolitis. Moreover, the chest CT showed bilateral, peripheral, and multifocal ground-glass opacities, consistent with COVID-19 pneumonia. We also aimed to emphasize the laboratory, clinical, and CT findings of the patient. (C) 2021 Elsevier Inc. All rights reserved.
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- 2021
45. COVID-19 During Pregnancy: The Role of the Mother and Baby in Every Decision
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Nazlı Çetin, Merve Türkarslan, Furkan Ufuk, Cihan Kabukçu, and Erhan Ugurlu
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Pulmonary and Respiratory Medicine ,Gynecology ,medicine.medical_specialty ,Pregnancy ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,business.industry ,medicine.medical_treatment ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Altered immunity ,medicine.disease ,medicine ,Caesarean section ,business - Abstract
Contracting COVID-19 during pregnancy is a clinical concern as knowledge of altered immunity is limited, and so cases should be considered separately in terms of diagnosis and treatment. Although there is no clear evidence that pregnancy increases the risk of COVID-19, it is thought that susceptibility to infection and the intensification of respiratory symptoms may be increased, given the physiological changes in pregnancy and increased mortality and morbidity in many viral diseases. Accordingly, the management of COVID-19 in pregnant patients and those considered among the high-risk groups represent a challenge for clinicians. Numerous studies of COVID-19 have been published to date or are ongoing, yet pregnant women are generally excluded from clinical studies. Clinical experiences and case reports occupy an important position in literature, and we present hare a case in which the diagnosis of a patient being followed by our clinic was delayed due to the absence of SARS CoV-2 in recurrent upper-respiratory-tract sampling, and whose clinical findings worsened with initial COVID-19 treatment during pregnancy. Her delivery by caesarean section (C-section) was the result of a multidisciplinary decision. We draw attention to the diagnostic process and treatment approach. (English) [ABSTRACT FROM AUTHOR] Gebelikte COVID-19, degisen immunite;tani ve tedavideki farkliliklar ile ayri ele alinmasi gereken, bilgilerimizin sinirli oldugu bir klinik tablodur. Gebelikte gerceklesen fizyolojik degisiklikler ve pek cok viral hastalikta artmis mortalite ve morbidite goz onune alindiginda, gebeligin enfeksiyonlara yatkinliga ve solunumsal semptomlarda siddetlenmeye neden olabilecegi dusunulmektedir. Bu nedenle riskli gruplar arasinda degerlendirilmesi gereken gebelerde COVID-19 yonetimi klinisyenler icin zorluklar icermektedir. COVID-19 ile ilgili cok sayida calisma yayinlanmis ya da devam etmekte olsa da gebeler genellikle klinik calismalarin disinda tutulmaktadir. Bu nedenle klinik deneyimler, olgu paylasimlari literaturde onemli bir yer tutmaktadir. Klinigimizde takip ettigimiz, tekrarlayan ust solunum yolu orneklemelerinde SARS CoV-2 saptanmamasi nedeniyle tanisi geciken, gebelikte kullanilabilen COVID-19 tedavisi altinda klinik bulgularda kotulesme olmasi uzerine multidisipliner yaklasim ile sezaryen karari alinarak tedavisi sekillendirilen olgumuzu, tani sureci ve tedavi yaklasimina dikkat cekerek sunmayi amacladik. (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Respiratory Case Reports is the property of LookUs Scientific and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2021
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46. Visual and Quantitative Assessment of COVID-19 Pneumonia on Chest CT: The Relationship with Disease Severity and Clinical Findings
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Semiha Orhan, Emin Demirel, Petek Konya, Furkan Kaya, Furkan Ufuk, and Neşe Demirtürk
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Adult ,Wuhan ,medicine.medical_specialty ,China ,Coronavirus disease 2019 (COVID-19) ,Chest ct ,Severity of Illness Index ,Procalcitonin ,Correlation ,quantitative CT ,Humans ,Medicine ,pneumonia ,Radiology, Nuclear Medicine and imaging ,visual CT ,Features ,Retrospective Studies ,CURB-65 ,Lung ,Receiver operating characteristic ,SARS-CoV-2 ,business.industry ,disease severity score ,COVID-19 ,Prognosis ,medicine.disease ,Pneumonia ,Cross-Sectional Studies ,medicine.anatomical_structure ,Radiology ,Tomography, X-Ray Computed ,business - Abstract
Background: Lungs are the primary organ involved in COVID-19, and the severity of pneumonia in COVID-19 patients is an important cause of morbidity and mortality. Aim: We aimed to evaluate the pneumonia severity through the visual and quantitative assessment on chest computed tomography (CT) in patients with coronavirus disease 2019 (COVID-19) and compare the CT findings with clinical and laboratory findings. Methods: We retrospectively evaluated adult COVID-19 patients who underwent chest CT along with theirclinical scores, laboratory findings, and length of hospital stay. Two independent radiologists visually evaluated the pneumonia severity on chest CT (VSQS). Quantitative CT (QCT) assessment was performed using a free DICOM viewer, and the percentage of the well-aerated lung (%WAL), high-attenuation areas (%HAA) at different threshold values, and mean lung attenuation (MLA) values were calculated. The relationship between CT scores and the clinical, laboratory data, and the length of hospital stay were evaluated in this cross-sectional study. The student's t-test and chi-square test were used to analyze the differences between the variables. The Pearson correlation test analyzed the correlation between the variables. The diagnostic performance of the variables was assessed using the receiver operating characteristic (ROC) analysis. Results: The VSQS and QCT scores were significantly correlated with procalcitonin, d-dimer, ferritin, and C-reactive protein levels. Both VSQ and QCT scores were significantly correlated with the disease severity (p < 0.001). Among the QCT parameters, the %HAA-600 value showed the best correlation with the VSQS (r = 730, p < 0.001). VSQS and QCT scores had high sensitivity and specificity in distinguishing disease severity and predicting prolonged hospitalization. Conclusion: The VSQS and QCT scores can help manage the COVID-19 and predict the duration of the hospitalization.
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- 2021
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47. Pleuroparenchymal fibroelastosis in a patient with systemic sclerosis
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Goksel Altinisik, Furkan Ufuk, and Uğur Karasu
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medicine.medical_specialty ,Scleroderma, Systemic ,Pyridones ,business.industry ,Pulmonary Fibrosis ,Vital Capacity ,MEDLINE ,Pleural Diseases ,Elastic Tissue ,Systemic scleroderma ,medicine.disease ,Dermatology ,Bronchiectasis ,Rheumatology ,Disease Progression ,medicine ,Humans ,Pulmonary Diffusing Capacity ,Female ,Pharmacology (medical) ,Lung Diseases, Interstitial ,Tomography, X-Ray Computed ,business ,Aged - Published
- 2020
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48. İntra-abdominal apselerde görüntüleme yöntemleri rehberliğinde kateterle perkütan drenaj
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Halil Serdar Aslan, Tugba Sari, Gözde Songut, Furkan Ufuk, Mustafa Ay, Muhammet Tekinhatun, Muhammet Arslan, and Muhammed Efe
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business.industry ,Radiology, Nuclear Medicine, Medical Imaging ,010102 general mathematics ,01 natural sciences ,Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme ,03 medical and health sciences ,0302 clinical medicine ,Perkütan drenaj,apse,mikrobiyoloji,batın içi ,Medicine ,030212 general & internal medicine ,0101 mathematics ,business ,Nuclear medicine ,Percutaneous drainage,abscess,microbiology,intra-abdominal - Abstract
AMAÇ : İntra-abdominal apselere görüntüleme eşliğinde yaptığımız perkütan drenaj işlemlerinin etkinliğini, işlemlerin hangi kılavuz yöntemle yapıldığını, komplikasyonlarını, alınan örneklerden gelen kültür antibiyogram sonuçlarını ve hastalarımızın demografik özellikleri ile klinik sonuçlarını değerlendirmektir.GEREÇ VE YÖNTEM : Çalışmamız tek merkezli, retrospektif bir kohort çalışmasıdır.01/06/2017 - 01/06/2019 tarihleri arasında hastanemiz girişimsel radyoloji bölümünde perkütan drenaj tedavisi uygulanan hastaların elektronik tıbbi kayıtları incelendi.Hastaların yaşı, cinsiyeti, işlemin yapılma yöntemi, kılavuz için kullanılan modalite, kullanılan kateter, oluşan komplikasyonlar, kateterin kaç gün kaldığı, hastaların kültür antibiyogram sonuçları araştırıldı.BULGULAR : Perkütan drenaj ile kateter yerleştirirken 187 işlemde Seldinger tekniği, 6 işlemde Trokar yöntemi uygulandığı görüldü. Kateter mal pozisyonu, kateter tıkanması, apsenin tekrarlaması, drenajın yeterli olmaması gibi nedenlerle perkütan drenaj yapılan apselerden 89 (%50) tanesine ikinci bir işlem yapmak gerekti ve tekrarlayan kateter drenajı yapılan hastaların 75’i (%42) tedaviden sonra iyileşti. İntra-abdominal apselerde uygulanan perkütan drenaj tedavisinde toplamda başarı oranımız %92 olarak hesaplandı.SONUÇ: İntra-abdominal apselerde apse ile ilişkili intra-abdominal patoloji bulunmuyorsa perkütan drenaj işlemi tedavide ilk seçenek olarak değerlendirilmektedir. Perkütan drenaj işleminin erken dönem komplikasyonları yok denecek kadar az olup güvenli ve etkili bir tedavi yöntemidir. Hangi apselere sadece antibiyotik tedavisi verilmesi gerektiği, hangilerine ince iğneyle aspirasyonun yapılacağı, hangilerine drenaj kateteri yerleştirilmesi gerektiği, hangilerine açık cerrahi tedavi gerektiğine dair çalışmalar yapılmasına ihtiyaç vardır., Purpose: Evaluation of the effectiveness of percutaneous drainage methods for intraabdominal abscesses, guiding method of the procedures, the complications, the culture antibiogram results from the samples taken, and the clinical results of our patients.Materials and methods: Our study is a single-center, retrospective cohort study. Electronic medical records of patients undergoing percutaneous drainage treatment in our hospital interventional radiology department between 01/06/2017-01/06/2019 were examined. The age and gender of the patients, the method of performing the procedure, the modality used for the guideline, the catheter used, the complications that occurred, the number of days the catheter was left, and the culture antibiogram results of the patients were investigated.Results: It was observed that 187 of the catheter placement procedures with percutaneous drainage were applied Seldinger technique and 6 of them Trocar method. Due to reasons such as catheter malposition, catheter occlusion, recurrence of the abscess, insufficient drainage, 89 (50%) of the abscesses with percutaneous drainage were required to perform a second procedure, and 75 (42%) of the patients who underwent recurrent catheter drainage recovered after the treatment. Our overall success rate in percutaneous drainage treatment for intra-abdominal abscesses was calculated as 84.9%. Conclusion: For intra-abdominal abscesses, if there is no intra-abdominal pathology associated with abscess, percutaneous drainage procedure is considered as the first choice in treatment. Early period complications of percutaneous drainage are almost none and it is a safe and effective treatment method. Studies need to be carried out on which abscesses should only be treated with antibiotics, which ones should be aspirated with a fine needle, which ones should be placed with a drainage catheter, and which ones require open surgical treatment.
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- 2020
49. Evaluation of disease severity with quantitative chest CT in COVID-19 patients
- Author
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Mahmut Demirci, Erhan Ugurlu, Tugba Sari, Nilufer Yigit, Furkan Ufuk, and Nazlı Çetin
- Subjects
Adult ,Male ,Coronavirus disease 2019 (COVID-19) ,Adolescent ,Chest ct ,Pulmonary disease ,Severity of Illness Index ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Cohen's kappa ,Disease severity ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Clinical severity ,Lung volumes ,Lung ,Aged ,Retrospective Studies ,Aged, 80 and over ,business.industry ,COVID-19 ,Objective method ,Middle Aged ,Thorax ,Chest Imaging: Original Article ,Female ,Cardiology and Cardiovascular Medicine ,business ,Nuclear medicine ,Tomography, X-Ray Computed - Abstract
PURPOSE: We aimed to assess the severity of coronavirus disease 2019 (COVID-19) pneumonia on computed tomography (CT) using quantitative (QCT) and semiquantitative (SCT) assessments and compare with the clinical findings. METHODS: Two observers independently examined the CT images of COVID-19 patients, and the SCT severity score was calculated. The SCT score was calculated as the sum of values ranging from 0 to 4, according to the volumetric rate of involvement for each lung lobe. In quantitative assessment, total lung volume (TLV) was automatically calculated from CT density values between -200 and -950 HU. Besides, healthy lung volume (HLV) was calculated from voxels between -800 and -950 HU. The QCT score was calculated with the following formula: (TLV - HLV / TLV) ×100. All patients were clinically divided into four groups: mild, common, severe, and critical. Interobserver agreement for SCT assessment was investigated using the Cohen's Kappa statistics (κ). Pearson's correlation coefficient was used for the relationship between continuous data. The diagnostic accuracy of SCT and QCT in the differentiation of clinically limited (mild, common) and extensive (severe, critical) disease was investigated using ROC analysis. RESULTS: Seventy-six patients with a diagnosis of COVID-19 were included. There was good agreement between the two observers in the SCT evaluation of pulmonary disease severity (κ = 0.796; 95% CI, 0.751-0.841). A significant correlation was found between QCT and SCT scores (P < 0.001, r = 0.661). Both QCT and SCT scores showed a significant correlation with clinical severity score (P < 0.001, r = 0.620 and P = 0.004, r = 0.529, respectively). The ROC analysis revealed the AUC of QCT and SCT for differentiation of limited and extensive disease as 0.873 (95% CI, 0.774-0.972) and 0.816 (95% CI, 0.673-0.959), respectively. CONCLUSION: The QCT assessment is an objective method in the evaluation of COVID-19 severity and is more successful than semiquantitative CT assessment to discriminate extensive from limited disease.
- Published
- 2020
50. Efficiency of Fat Suppression in T1-Weighted Inner Ear Magnetic Resonance Imaging: Multipoint Dixon Method Versus Hybrid Techniques
- Author
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Pınar Çakmak, Ahmet Baki Yagci, Vefa Çakmak, Ergin Sagtas, Furkan Ufuk, and Duygu Herek
- Subjects
inner ear ,Magnetic Resonance Spectroscopy ,Image quality ,Fat suppression ,Inversion-Recovery ,Mr ,Signal-To-Noise Ratio ,vertigo ,Nuclear magnetic resonance ,SPAIR ,Temporal bone ,medicine ,T1 weighted ,Humans ,Radiology, Nuclear Medicine and imaging ,Inner ear ,Physics ,medicine.diagnostic_test ,signal to noise ratio ,spinal cord ,Magnetic resonance imaging ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Signal-to-noise ratio (imaging) ,Adipose Tissue ,Ear, Inner ,CHESS ,Stir Techniques - Abstract
Background: Temporal bone is a region where fat suppression is difficult due to the inhomogeneity of various structures with different molecular properties. Introduction: We aimed to determine the most effective fat suppression sequence in order to increase the visibility of the inner ear region. Methods: The hybrid techniques and T1-Weighted mDIXON images of 40 patients with Magnetic Resonance (MR) imaging of the inner ear were prospectively compared by two experienced radiologists in terms of fat suppression efficacy. In all fat-suppressed sequences, the Signal to Noise Ratio (SNR), the spinal cord signal intensity / mean fat signal intensity ratio and spinal cord signal to noise ratio were calculated. The suppression efficacy of MR techniques for fat areas in the inner ear was visually graded. Results: Qualitative assessment of image quality due to fat suppression in the inner ear was made; the Dixon technique performed significantly better than SPAIR and SPIR techniques (p Conclusion: The Dixon technique exhibited higher image quality and fat suppression efficiency than the hybrid techniques in the MR imaging of the inner ear.
- Published
- 2020
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