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1. PMMA-cement anterior column reconstruction in surgical treatment of spondylodiscitis

Author

X. Banse, L. Kaminski, N. Irda, C. Briquet, O. Cornu, and J.-C. Yombi

Subjects
Spondylodiscitis, Vertebral osteomyelitis, Spine surgery, PMMA cement, Neurology. Diseases of the nervous system, RC346-429
Abstract

Introduction: and research question: This paper explains how antibiotic loaded cement can be used in surgical treatment of spondylodiscitis to reconstruct the anterior column of the spine. Material and methods: 35 consecutive surgical procedures performed for spondylodiscitis were collected over a 11-year period and charts were reviewed. Most infections were caused mainly by staphylococcus spp (n = 16), streptococcus spp (n = 8) and pseudomonas spp (n = 4). Most patients had long standing but unsuccessful antibiotic therapy (median 42 days). Other indications included instability, neurologic deficit, abscess, and patients were generally in very poor medical condition. Results: Anterior debridement was followed by a partial cavity filling with surgical high viscosity PMMA cement in all cases. Cement was a high viscosity gentamycin loaded cement, that was placed in the cavity created by debridement under the direct eye control. In 25 cases, a part of the cavity was filled with freeze dried cancellous bone allograft rehydrated in rifampicin. Spine was further stabilized with an anterior plate in 15 cases, with short (+1/+1) posterior instrumentation in 5 cases, and a long (≥ +2/+2) posterior instrumentation in 11 cases. In four patients, spine was left un-instrumented. Immediate, unrestricted mobilization was always authorized after surgery. None of the patients were reoperated neither for mechanical failure nor for infection relapse. Conclusion: This report supports the idea that surgical bone cement is an efficient gap filler when used through anterior approach. For small as well as for large defects, it can help to reconstruct the anterior column and locally control the infection in combination with additional stabilization and optimal intravenous and oral antibiotic treatment.

Published
2022
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2. Irreducible ankle fracture dislocation due to posterior tibialis tendon interposition: Diagnostic and clues for early management – A case report

Author

Loïc Thoreau, L. Kaminski, and Dan C. Putineanu

Subjects
Surgery, RD1-811
Abstract

Irreducible fracture dislocation of the ankle is a rare condition. Multiple cases have been described throughout the literature. Different known etiologies involve the distal fibula, deltoïd ligament and tendons of the posteromedial malleolar region. More specifically, trapping of the Posterior tibialis tendon has been described at several levels from the inside of the ankle joint, through the syndesmosis and in some cases in the fibula tibial interosseous space depending on the energy of trauma. We hereafter propose a case report and a review of previous cases of posterior tibialis tendon dislocation proximally in the interosseous space of the lower leg. The aim of this review is to point out common features and clues for early management in order to avoid overlooking these rare lesions as they may lead to major functional impairment of the ankle joint. Keywords: Ankle fracture-dislocation, Posterior tibialis tendon interposition, Trauma

Published
2019
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3. Synthesizing the connections between environmental disturbances and zoonotic spillover

Author

JOEL HENRIQUE ELLWANGER, PHILIP MARTIN FEARNSIDE, MARINA ZILIOTTO, JACQUELINE MARÍA VALVERDE-VILLEGAS, ANA BEATRIZ G. DA VEIGA, GUSTAVO F. VIEIRA, EVELISE BACH, JÁDER C. CARDOSO, NÍCOLAS FELIPE D. MÜLLER, GABRIEL LOPES, LÍLIAN CAESAR, BRUNA KULMANN-LEAL, VALÉRIA L. KAMINSKI, ETIELE S. SILVEIRA, FERNANDO R. SPILKI, MATHEUS N. WEBER, SABRINA E. DE MATOS ALMEIDA, VANUSA P. DA HORA, and JOSÉ ARTUR B. CHIES

Subjects
Amazon Forest, biodiversity, disease ecology, outbreak, spillover, zoonosis, Science
Abstract

Abstract Zoonotic spillover is a phenomenon characterized by the transfer of pathogens between different animal species. Most human emerging infectious diseases originate from non-human animals, and human-related environmental disturbances are the driving forces of the emergence of new human pathogens. Synthesizing the sequence of basic events involved in the emergence of new human pathogens is important for guiding the understanding, identification, and description of key aspects of human activities that can be changed to prevent new outbreaks, epidemics, and pandemics. This review synthesizes the connections between environmental disturbances and increased risk of spillover events based on the One Health perspective. Anthropogenic disturbances in the environment (e.g., deforestation, habitat fragmentation, biodiversity loss, wildlife exploitation) lead to changes in ecological niches, reduction of the dilution effect, increased contact between humans and other animals, changes in the incidence and load of pathogens in animal populations, and alterations in the abiotic factors of landscapes. These phenomena can increase the risk of spillover events and, potentially, facilitate new infectious disease outbreaks. Using Brazil as a study model, this review brings a discussion concerning anthropogenic activities in the Amazon region and their potential impacts on spillover risk and spread of emerging diseases in this region.

Published
2022
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5. DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes

Author

Thomas Donner, P. Rezaeian, John I. Malone, Sharon B. Schwartz, Xiaoyu Gao, Szilard Kiss, Matthew J. Budoff, David R. Sell, A. Dwoskin, Ronald J. Prineas, C. Pittman, M. Reid, C. McDonald, S. Caulder, M. Szpiech, Oscar B. Crofford, Rachel G. Miller, Louis A. Lobes, M. Patronas, C. Canny, M. E. Lackaye, Sandra R. Montezuma, Richard M. Bergenstal, Patricia Gatcomb, Julie A. Stoner, H. Pan, James L. Kinyoun, J. Mortenson, Osama Hamdy, Connie Fountain, David D. Moore, Kusiel Perlman, R. Trail, David A. Lee, J. Sheindlin, Samuel Dagogo-Jack, Jeffrey L. Mahon, Jill P. Crandall, L. Gill, T. Thompson, Lee M. Jampol, K. Koushan, David S. Schade, J. Brown-Friday, M. Basco, S. Dunnigan, J. Bylsma, R. Birk, L. H. Ketai, J. Hotaling, Stephen W. Scherer, W. Mestrezat, Stephan Villavicencio, R. Lyon, M. Carney, John Kramer, Sunder Mudaliar, David M. Nathan, M. Moran, F. Leandre, James W. Albers, L. Survant, Joseph F. Polak, Manjot K. Gill, Anton Orlin, M. Prince, Pamela A. Silver, Amy K. Saenger, John D. Brunzell, Kathleen E. Bainbridge, L. Babbione, Amisha Wallia, J. Vaccaro-Kish, Bradley D. Jones, M. Hebdon, L. McKenzie, Richard M. Hoffman, S. Chang, C. Siebert, George S. Sharuk, D. Counts, A. Lucas, P. Ramos, N. Burkhart, N. Bakshi, N. Flaherty, D. Kenny, M. Driscoll, Harjit Chahal, Ronald K. Mayfield, S. Hensley, E. Weimann, M. Franz, Martin J. Stevens, N. S. Gregory, Christopher J. O'Donnell, J. Laechelt, Pamela Ossorio, Jerry P. Palmer, Rama Natarajan, G. Ziegler, K. Martin, R. Beaser, C. Beck, L. Zhang, T. J. Declue, David M. Kendall, H. Solc, A. Vella, H. Martinez, Cormac T. Taylor, S. Neill, Douglas A. Greene, P. Lee, D. Norman, Andrew J. Barkmeier, Dean P. Hainsworth, Alka Jain, Sapna Gangaputra, N. Thangthaeng, Lorraine Thomas, Michael H. Brent, M. Bracey, Philip Raskin, Q. Clemens, Barbara H. Braffett, Mark S. Mandelcorn, Lloyd Paul Aiello, John E. Godine, T. Speigelberg, R. Chan, R. Hanna, Shelley B. Bull, William I. Sivitz, R. Sussman, C. Kwong, S. Cercone, P. Hollander, N. Leloudes, Joseph M. Terry, J. Wesche, E. A. Tanaka, D. Rosenberg, Wanjie Sun, L. Sun, Tom Clark, Deborah K. Schlossman, Louis M. Luttrell, R. Dunn, A. Farr, K. McVary, Gayle M. Lorenzi, A. Joseph, Catherine C. Cowie, M. Barr, D. Zimbler, S. Mendley, S. Schussler, N. Grove, Matthew D. Davis, Jong Mu Sun, Sophie Rogers, John P. Bantle, Brandy N. Rutledge, Senda Ajroud-Driss, Vincent M. Monnier, Cladd E. Stevens, Y. G. He, M. Phillips, C. Williams, J. MacIndoe, Kaleigh Farrell, Helen Lambeth, Ayad A. Jaffa, J. Quin, Morey W. Haymond, R. Kirby, D. Steinberg, William H. Herman, M. Mech, Arup Das, Robert Detrano, J. Brown, D. McMillan, Linda Snetselaar, Mark W. Johnson, R. Zeitler, T. Taylor, Peter R. Pavan, Michael H. Goldbaum, Bruce A. Perkins, R. G. Campbell, David A. Nicolle, R. J. van der Geest, Irene Hramiak, D. Freking, Lucy A. Levandoski, S. Colson, Charles Campbell, Victoria R. Trapani, Lawrence J. Singerman, D. Meyer, W. Tang, J. Soule, Anita Harrington, Julie A. Nelson, John A. Colwell, Naji Younes, P. Salemi, K. Hansen, Trevor J. Orchard, S. Huddleston, L. Steranchak, C. Sommer, G. Castle, J. Ginsberg, Paula McGee, V. Gama, John Dupre, Z. Strugula, M. Swenson, N. Wong, David A. Bluemke, M. Nutaitis, Anita Agarwal, M. Lin, K. Nickander, Elsayed Z. Soliman, Joao A. Lima, M. L. Schluter, Fred W. Whitehouse, Lisa Diminick, C. Cornish, M. Spencer, Daniel T. Lackland, Ionut Bebu, Hunter Wessells, S. Yacoub-Wasef, A. Determan, L. Van Ottingham, Howard Wolpert, R. Ehrlich, A. Blevins, L. Jovanovic, D. Finegold, Davida F. Kruger, Jye-Yu C. Backlund, K. Chan, Timothy J. Murtha, R. K. Mayfield, Robert W. Cavicchi, Maria F. Lopes-Virella, Thomas A. Weingeist, K. Lee, Mary E. Larkin, B. Blodi, J. Gott, Timothy J. Lyons, J. Selby, Chris Ryan, J. Harth, P. Pugsley, L. Keasler, John D. Maynard, Paul G. Arrigg, Amy B. Karger, P. Colby, J. Farquhar, Mark H. Schutta, Murk-Hein Heinemann, Kathie L. Hermayer, B. Bosco, C. Lovell, A. Bhan, A. Galprin, M. Cayford, M. Schumer, John E. Chapin, D. Rubinstein, F. Miao, V. Asuquo, Catherine L. Martin, Rodney A. Lorenz, Samuel S. Engel, L. Funk, Cyndi F. Liu, Barbara J. Maschak-Carey, Stephen S. Feman, P. Lindsey, M. Giotta, Philip A. Low, S. Kwon, R. Fahlstrom, A. Iannacone, B. French, H. Remtema, L. Cimino, S. Barron, J. McConnell, Jane L. Lynch, L. Kim, T. Williams, A. Degillio, Blanche M. Chavers, M. Novak, Julio V. Santiago, Ronald P. Danis, P. Gaston, Tae Sup Lee, T. Woodfill, R. Cuddihy, Scott M. Steidl, Alanna C. Morrison, E. Ryan, D. Lawrence, D. Cros, T. Adkins, D. Adelman, L. Dews, Patricia A. Cleary, J. Parker, L. Olmos De Koo, C. Kim, Mark R. Palmert, P. Astelford, Stefan Fritz, B. Olson, Kelvin C. Fong, Alan M. Jacobson, Stanley L. Hazen, D. Hornbeck, K. Folino, M. L. Bernal, Gabriel Virella, William V. Tamborlane, Neil H. White, Daniel L. McGee, Denis Daneman, H. Shamoon, William Dahms, S. Elsing, S. Brink, J. Ahern, Delnaz Roshandel, John M. Pach, N. W. Rodger, E. Cupelli, Dara D. Koozekanani, Abbas E. Kitabchi, K. Stoessel, B. Petty, Jamie R. Wood, J. Seegmiller, T. Strand, Y. Li, Eva L. Feldman, Larry Rand, Robert C. Colligan, T. Smith, A. Carlson, David J. Brillon, Margaret L. Bayless, M. Ong, S. Darabian, W. Hsu, Janet E. Olson, B. Rogness, N. Silvers, M. Pfiefer, B. Schaefer, E. Mendelson, S. Braunstein, Maren Nowicki, R. Reed, James S. Floyd, Z. M. Zhang, T. Sandford, R. B. Avery, A. Pratt, Paolo S. Silva, H. Bode, Alexander J. Brucker, Nikhil D. Patel, Alexander R. Lyon, M. Jenner, N. Wimmergren, L. Tuason, J. Rosenzwieg, D. J. Becker, C. Gauthier-Kelly, M. Richardson, Richard S. Crow, Andrew D. Paterson, Mark E. Molitch, Suzanne M. Strowig, S. Pendegast, M. Burger, Ramzi K. Hemady, J. Dingledine, I. H. de Boer, L. Mayer, F. Perdikaris, Om P. Ganda, F. Thoma, Karen J. Cruickshanks, Abraham Thomas, K. Klumpp, Jerry D. Cavallerano, D. Zheng, Annette Barnie, J. L. Canady, C. Wigley, David G. Miller, Sheila Smith-Brewer, D. Ostrowski, P. Crawford, K. Kelly, Robert G. Devenyi, B. Zimmerman, Susan M. Hitt, C. Johnson, L. Gurry, R. Jarboe, E. Angus, David E. Goldstein, A. Killeen, H. Schrott, Orville G. Kolterman, Mark R. Burge, Michael Rubin, J. Lipps Hagan, Alicia J. Jenkins, Hugh D. Wabers, R. Warhol, Edward Chaum, Karen L. Jones, L. Spillers, C. Miao, J. K. Jones, Angelo J. Canty, Rickey E. Carter, Evrim B. Turkbey, B. Burzuk, R. Woodwick, Evica Simjanoski, Michael W. Steffes, S. Crowell, Suresh D. Shah, H. Ricks, J. D. Carey, Paul A. Edwards, S. Holt, W. F. Schwenk, Ronald J. Oudiz, E. Brown, J. Heier, R. L. Ufret-Vincenty, L. M. Aiello, Robert A. Rizza, Karen L. Anderson, Valerie L. Arends, J. Giangiacomo, R. Liss, Aruna V. Sarma, B. Levy, Ellen J. Anderson, S. Catton, P. Callahan, Rodica Pop-Busui, S. Debrabandere, S. Moser, Bernard H. Doft, A. Malayeri, C. Johannes, R. Ramker, J. Rich, M. Fox, Rukhsana G. Mirza, Katherine A. Morgan, Thomas J. Songer, C. Shah, H. Engel, Saul M. Genuth, S. Ferguson, Anushka Patel, C. Haggan, P. Lou, J. Gordon, M. B. Murphy, D. Sandstrom, Dawn M. Ryan, Daniel H. O'Leary, B. Gloeb, Lois E. Schmidt, H. Zegarra, D. Dalton, W. Brown, Tom G. Sheidow, Margaret E. Stockman, Shyam M. Thomas, Charles McKitrick, Jyotika K. Fernandes, P. A. Bourne, L. Baker, G. Friedenberg, Allan Gordon, Allan L. Drash, S. Yoser, D. Wood, S. Johnsonbaugh, A. De Manbey, L. Kaminski, M. May, L. Bestourous, A. Kowarski, M. Geckle, M. Hartmuller, Michael Bryer-Ash, S. List, F. Goetz, V. Reppucci, D. Etzwiler, Rose A. Gubitosi-Klug, M. Brabham, E. Golden, A. Nayate, J. Hu, M. McLellan, Ronald Klein, N. Rude, B. Vittetoe, John M. Lachin, M. Christofi, Zhuo Chen, Isaac Boniuk, C. Strauch, K. Gunyou, L. Delahanty, W. T. Garvey, Andrew P. Boright, Larry D. Hubbard, D. Weiss, Igor Grant, Jonathan Q. Purnell, Jean M. Bucksa, N. Olson, and B. Zinman

Subjects
0301 basic medicine, Adult, Male, medicine.medical_specialty, Diabetic neuropathy, Adolescent, 030209 endocrinology & metabolism, Gastroenterology, Nephropathy, Epigenesis, Genetic, Diabetic complications, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Diabetic Neuropathies, Internal medicine, Diabetes mellitus, Albumins, Genetics, Medicine, Humans, Molecular Biology, Genetics (clinical), Whole blood, Oligonucleotide Array Sequence Analysis, Type 1 diabetes, business.industry, Research, dNaM, DNA methylation age, DNA Methylation, medicine.disease, 030104 developmental biology, Blood pressure, Peripheral neuropathy, Diabetes Mellitus, Type 1, CpG Islands, Female, business, Developmental Biology, Genome-Wide Association Study
Abstract

Background Many CpGs become hyper or hypo-methylated with age. Multiple methods have been developed by Horvath et al. to estimate DNA methylation (DNAm) age including Pan-tissue, Skin & Blood, PhenoAge, and GrimAge. Pan-tissue and Skin & Blood try to estimate chronological age in the normal population whereas PhenoAge and GrimAge use surrogate markers associated with mortality to estimate biological age and its departure from chronological age. Here, we applied Horvath’s four methods to calculate and compare DNAm age in 499 subjects with type 1 diabetes (T1D) from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study using DNAm data measured by Illumina EPIC array in the whole blood. Association of the four DNAm ages with development of diabetic complications including cardiovascular diseases (CVD), nephropathy, retinopathy, and neuropathy, and their risk factors were investigated. Results Pan-tissue and GrimAge were higher whereas Skin & Blood and PhenoAge were lower than chronological age (p < 0.0001). DNAm age was not associated with the risk of CVD or retinopathy over 18–20 years after DNAm measurement. However, higher PhenoAge (β = 0.023, p = 0.007) and GrimAge (β = 0.029, p = 0.002) were associated with higher albumin excretion rate (AER), an indicator of diabetic renal disease, measured over time. GrimAge was also associated with development of both diabetic peripheral neuropathy (OR = 1.07, p = 9.24E−3) and cardiovascular autonomic neuropathy (OR = 1.06, p = 0.011). Both HbA1c (β = 0.38, p = 0.026) and T1D duration (β = 0.01, p = 0.043) were associated with higher PhenoAge. Employment (β = − 1.99, p = 0.045) and leisure time (β = − 0.81, p = 0.022) physical activity were associated with lower Pan-tissue and Skin & Blood, respectively. BMI (β = 0.09, p = 0.048) and current smoking (β = 7.13, p = 9.03E−50) were positively associated with Skin & Blood and GrimAge, respectively. Blood pressure, lipid levels, pulse rate, and alcohol consumption were not associated with DNAm age regardless of the method used. Conclusions Various methods of measuring DNAm age are sub-optimal in detecting people at higher risk of developing diabetic complications although some work better than the others.

Published
2020

6. Follicle-stimulating hormone receptors expression in ovine corpora lutea during luteal phase: effect of nutritional plane and follicle-stimulating hormone treatment

Author

Veselina Valkov, Dale A. Redmer, Samantha L. Kaminski, Sheri T. Dorsam, Casie S. Bass, Anna T. Grazul-Bilska, and Arshi Reyaz

Subjects
endocrine system, medicine.medical_specialty, Nutritional Status, Luteal phase, Biology, 03 medical and health sciences, Follicle-stimulating hormone, 0302 clinical medicine, Endocrinology, Food Animals, Corpus Luteum, Internal medicine, medicine, Animals, Receptor, Messenger RNA, 030219 obstetrics & reproductive medicine, Sheep, 0402 animal and dairy science, 04 agricultural and veterinary sciences, 040201 dairy & animal science, medicine.anatomical_structure, Gene Expression Regulation, Hormone receptor, Immunohistochemistry, Receptors, FSH, Animal Science and Zoology, Female, Follicle Stimulating Hormone, Corpus luteum, Endocrine gland
Abstract

Corpus luteum (CL), a transient endocrine gland critical for reproductive cyclicity and pregnancy maintenance, is controlled by numerous regulatory factors. Although LH is widely recognized as the major regulator, other factors may also affect luteal functions. It has been demonstrated that FSH receptors (FSHR) are expressed not only in ovarian follicles but also in other tissues within the reproductive tract, including the CL. To evaluate FSHR expression in nontreated (nonsuperovulated; experiment 1) or FSH-treated (superovulated; experiment 2) sheep fed a control (C; maintenance), excess (O; 2 × C), or restricted (U; 0.6 × C) diet, CL were collected at the early, mid and/or late luteal phases (n = 5-7 per group). Protein and messenger RNA (mRNA) expression of FSHR were detected in the CL from all groups using immunohistochemistry followed by image analysis and quantitative RT-PCR, respectively. Follicle-stimulating hormone receptor was immunolocalized to steroidogenic small and large and nonsteroidogenic luteal cells. In both experiments, FSHR protein expression was not affected by stage of luteal development or diet. In experiment 1, expression of mRNA for all FSHR variants was greater (P0.02 to 0.0003) at the late phase than mid or early luteal phase, and in experiment 2, it was greater (P0.001) at the mid than early luteal phase. Plane of nutrition did not affect FSHR mRNA expression. Comparison of FSH-treated with nontreated ewes demonstrated that FSH increased FSHR protein expression by 1.5- to 2-fold (P0.0001) in all groups, and mRNA expression by 7- to 30-fold (P0.001) for (1) FSHR-1 in all groups except U at the early luteal phase, (2) FSHR-2 in C, O, and U at the mid-phase, but not early luteal phase, and (3) FSHR-3 in U at the mid-luteal phase. Our data demonstrate that (1) FSHRs are expressed in ovine CL at several stages of luteal development, (2) FSHR protein expression does not change during the luteal phase and is not affected by diet, (3) FSHR mRNA expression not only depends on the stage of the estrous cycle but also not affected by diet in nonsuperovulated or superovulated ewes, and (4) in vivo FSH treatment enhanced FSHR protein and/or mRNA expression in the CL depending on diet and phase of the estrous cycle. Presence of FSHR in the CL indicates a regulatory role of FSH in luteal function in sheep. As very little is known about the possible role of FSH and FSHR in luteal functions, further studies should be undertaken to elucidate the endocrine, molecular, and cellular mechanisms of FSH effects on the CL.

Published
2019

7. Connecticut pet shop laws

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Pet shops Law and legislation Connecticut., Animal welfare Law and legislation Connecticut., Animal welfare Law and legislation., Pet shops Law and legislation., Connecticut.
Abstract

Summarizes Connecticut's pet shop laws.

Published
2019

8. State-level regulation of PFAS

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Drinking water Standards States. United States, Drinking water Standards Connecticut., Drinking water Law and legislation States. United States, Drinking water Law and legislation Connecticut., Perfluorinated chemicals Health aspects., Environmental toxicology., Environmental health., Eau potable Normes États. États-Unis, Eau potable Normes Connecticut., Écotoxicologie., Drinking water Law and legislation., Drinking water Law and legislation U.S. states., Drinking water Standards., Drinking water Standards U.S. states., Environmental health., Environmental toxicology., Connecticut.
Abstract

Discusses state laws regulating per- and polyfluoroalkyl substances (PFAS) in drinking water and products. Summarizes similar proposed legislation in Connecticut.

Published
2019

9. Acts affecting animals & agriculture

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Animal welfare Law and legislation Connecticut., Animals Law and legislation Connecticut., Agricultural laws and legislation Connecticut., Agricultural laws and legislation., Animal welfare Law and legislation., Animals Law and legislation., Connecticut.
Abstract

Discusses new laws (public acts and special acts) significantly affecting animals and agriculture enacted and adopted during the 2019 regular session.

Published
2019

10. Washington state laws regulating PFAS

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Perfluorinated chemicals Health aspects., Environmental toxicology., Environmental health., Food law and legislation Washington (State), Fire fighting equipment industry Law and legislation Washington (State), Écotoxicologie., Environmental health., Environmental toxicology., Food law and legislation., Washington (State)
Abstract

Discusses per- and polyfluoroalkyl substances (PFAS) and briefly summarizes Washington state laws regulating PFAS in food packaging and firefighter equipment and foam.

Published
2019

11. Midyear formulary changes : comparing Illinois law to a Connecticut proposal

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Medicare Law and legislation Illinois., Medicare Law and legislation Connecticut., Pharmaceutical services insurance Law and legislation Illinois., Pharmaceutical services insurance Law and legislation Connecticut., Drugs Prescribing Law and legislation Illinois., Drugs Prescribing Law and legislation Connecticut., Drugs Prescribing Law and legislation., Medicare Law and legislation., Pharmaceutical services insurance Law and legislation., Connecticut., Illinois.
Abstract

Compares and summarizes Illinois Public Act (PA) 100-1052 (HB 4146 (2018)) and Connecticut's uncalled amendment LCO No. 4155 to SB 379 (2018), which did not become law.

Published
2019

12. Industrial hemp laws in select states

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Hemp industry Law and legislation Kentucky., Hemp industry Law and legislation Massachusetts., Hemp industry Law and legislation Vermont., Hemp industry Law and legislation Wisconsin., Hemp industry Law and legislation., Kentucky., Massachusetts., Vermont., Wisconsin.
Abstract

Compares and summarizes industrial hemp laws in four states: Kentucky, Massachusetts, Vermont, and Wisconsin.

Published
2019

13. Oxidative Stress and Cardiovascular Risk in Type 1 Diabetes Mellitus: Insights From the DCCT/EDIC Study

Author

W.H. Wilson Tang, Paula McGee, John M. Lachin, Daniel Y. Li, Byron Hoogwerf, Stanley L. Hazen, D.M. Nathan, B. Zinman, O. Crofford, S. Genuth, J. Brown‐Friday, J. Crandall, H. Engel, S. Engel, H. Martinez, M. Phillips, M. Reid, H. Shamoon, J. Sheindlin, R. Gubitosi‐Klug, L. Mayer, S. Pendegast, H. Zegarra, D. Miller, L. Singerman, S. Smith‐Brewer, M. Novak, J. Quin, Saul Genuth, M. Palmert, E. Brown, J. McConnell, P. Pugsley, P. Crawford, W. Dahms, N.S. Gregory, M.E. Lackaye, S. Kiss, R. Chan, A. Orlin, M. Rubin, D. Brillon, V. Reppucci, T. Lee, M. Heinemann, S. Chang, B. Levy, L. Jovanovic, M. Richardson, B. Bosco, A. Dwoskin, R. Hanna, S. Barron, R. Campbell, A. Bhan, D. Kruger, J.K. Jones, P.A. Edwards, J.D. Carey, E. Angus, A. Thomas, A. Galprin, M. McLellan, F. Whitehouse, R. Bergenstal, M. Johnson, K. Gunyou, L. Thomas, J. Laechelt, P. Hollander, M. Spencer, D. Kendall, R. Cuddihy, P. Callahan, S. List, J. Gott, N. Rude, B. Olson, M. Franz, G. Castle, R. Birk, J. Nelson, D. Freking, L. Gill, W. Mestrezat, D. Etzwiler, K. Morgan, L.P. Aiello, E. Golden, P. Arrigg, V. Asuquo, R. Beaser, L. Bestourous, J. Cavallerano, R. Cavicchi, O. Ganda, O. Hamdy, R. Kirby, T. Murtha, D Schlossman, S. Shah, G. Sharuk, P. Silva, P. Silver, M. Stockman, J. Sun, E. Weimann, H. Wolpert, L.M. Aiello, A. Jacobson, L. Rand, J. Rosenzwieg, M.E. Larkin, M. Christofi, K. Folino, J. Godine, P. Lou, C. Stevens, E. Anderson, H. Bode, S. Brink, C. Cornish, D. Cros, L. Delahanty, eManbey, C. Haggan, J. Lynch, C. McKitrick, D. Norman, D. Moore, M. Ong, C. Taylor, D. Zimbler, S. Crowell, S. Fritz, K. Hansen, C. Gauthier‐Kelly, F.J. Service, G. Ziegler, A. Barkmeier, L. Schmidt, B. French, R. Woodwick, R. Rizza, W.F. Schwenk, M. Haymond, J. Pach, J. Mortenson, B. Zimmerman, A. Lucas, R. Colligan, L. Luttrell, M. Lopes‐Virella, S. Caulder, C. Pittman, N. Patel, K. Lee, M. Nutaitis, J. Fernandes, K. Hermayer, S. Kwon, A Blevins, J. Parker, J. Colwell, D. Lee, J. Soule, P. Lindsey, M. Bracey, A. Farr, S. Elsing, T. Thompson, J. Selby, T. Lyons, S. Yacoub‐Wasef, M. Szpiech, D. Wood, R. Mayfield, M. Molitch, D. Adelman, S. Colson, L. Jampol, A. Lyon, M. Gill, Z. Strugula, L. Kaminski, R. Mirza, E. Simjanoski, D. Ryan, C. Johnson, A. Wallia, S. Ajroud‐Driss, P. Astelford, N. Leloudes, A. Degillio, B. Schaefer, S. Mudaliar, G Lorenzi, M. Goldbaum, K. Jones, M. Prince, M. Swenson, I. Grant, R. Reed, R. Lyon, O. Kolterman, M. Giotta, T. Clark, G. Friedenberg, W.I. Sivitz, B. Vittetoe, J. Kramer, M. Bayless, R. Zeitler, H. Schrott, N. Olson, L. Snetselaar, R. Hoffman, J. MacIndoe, T. Weingeist, C. Fountain, R. Miller, S. Johnsonbaugh, M. Patronas, M. Carney, S. Mendley, P. Salemi, R. Liss, M. Hebdon, D. Counts, T. Donner, J. Gordon, R. Hemady, A. Kowarski, D. Ostrowski, S. Steidl, B. Jones, W.H. Herman, C.L. Martin, R. Pop‐Busui, D.A. Greene, M.J. Stevens, N. Burkhart, T. Sandford, J. Floyd, J. Bantle, N. Flaherty, J. Terry, D. Koozekanani, S. Montezuma, N. Wimmergren, B. Rogness, M. Mech, T. Strand, J. Olson, L. McKenzie, C. Kwong, F. Goetz, R. Warhol, D. Hainsworth, D. Goldstein, S. Hitt, J. Giangiacomo, D.S Schade, J.L. Canady, M.R. Burge, A. Das, R.B. Avery, L.H. Ketai, J.E. Chapin, M.L. Schluter, J. Rich, C. Johannes, D. Hornbeck, M. Schutta, P.A. Bourne, A. Brucker, S. Braunstein, S. Schwartz, B.J. Maschak‐Carey, L. Baker, T. Orchard, L. Cimino, T. Songer, B. Doft, S. Olson, D. Becker, D. Rubinstein, R.L. Bergren, J. Fruit, R. Hyre, C. Palmer, N. Silvers, L. Lobes, P. Paczan Rath, P.W. Conrad, S. Yalamanchi, J. Wesche, M. Bratkowksi, S. Arslanian, J. Rinkoff, J. Warnicki, D. Curtin, D. Steinberg, G. Vagstad, R. Harris, L. Steranchak, J. Arch, K. Kelly, P. Ostrosaka, M. Guiliani, M. Good, T. Williams, K. Olsen, A. Campbell, C. Shipe, R. Conwit, D. Finegold, M. Zaucha, A. Drash, A. Morrison, J.I. Malone, M.L. Bernal, P.R. Pavan, N. Grove, E.A. Tanaka, D. McMillan, J. Vaccaro‐Kish, L. Babbione, H. Solc, T.J. DeClue, S. Dagogo‐Jack, C. Wigley, H. Ricks, A. Kitabchi, E. Chaum, M.B. Murphy, S. Moser, D. Meyer, A. Iannacone, S. Yoser, M. Bryer‐Ash, S. Schussler, H. Lambeth, P. Raskin, S. Strowig, M. Basco, S. Cercone, A. Barnie, R. Devenyi, M. Mandelcorn, M. Brent, S. Rogers, A. Gordon, N. Bakshi, B. Perkins, L. Tuason, F. Perdikaris, R. Ehrlich, D. Daneman, K. Perlman, S Ferguson, J. Palmer, R. Fahlstrom, I.H. de Boer, J. Kinyoun, L. Van Ottingham, S. Catton, J. Ginsberg, C. McDonald, J. Harth, M. Driscoll, T. Sheidow, J. Mahon, C. Canny, D. Nicolle, P. Colby, J. Dupre, I. Hramiak, N.W. Rodger, M. Jenner, T. Smith, W. Brown, M. May, J. Lipps Hagan, A. Agarwal, T. Adkins, R. Lorenz, S. Feman, L. Survant, N.H. White, L. Levandoski, G. Grand, M. Thomas, D. Joseph, K. Blinder, G. Shah, D. Burgess, I. Boniuk, J. Santiago, W. Tamborlane, P. Gatcomb, K. Stoessel, P. Ramos, K. Fong, P. Ossorio, J. Ahern, L. Meadema‐Mayer, C. Beck, K. Farrell, J Quin, P. Gaston, R. Trail, J. Lachin, J. Backlund, I. Bebu, B. Braffett, L. Diminick, X. Gao, W. Hsu, K. Klumpp, H. Pan, V. Trapani, P. Cleary, P. McGee, W. Sun, S. Villavicencio, K. Anderson, L. Dews, Naji Younes, B. Rutledge, K. Chan, D. Rosenberg, B. Petty, A. Determan, D. Kenny, C. Williams, C. Cowie, C. Siebert, M. Steffes, V. Arends, J. Bucksa, M. Nowicki, B. Chavers, D. O'Leary, J. Polak, A. Harrington, L. Funk, R Crow, B. Gloeb, S. Thomas, C. O'Donnell, E.Z. Soliman, Z.M. Zhang, Y. Li, C. Campbell, L. Keasler, S. Hensley, J. Hu, M. Barr, T. Taylor, R. Prineas, E.L. Feldman, J.W. Albers, P. Low, C. Sommer, K. Nickander, T. Speigelberg, M. Pfiefer, M. Schumer, M. Moran, J. Farquhar, C. Ryan, D. Sandstrom, M. Geckle, E. Cupelli, F. Thoma, B. Burzuk, T. Woodfill, R. Danis, B. Blodi, D. Lawrence, H. Wabers, S. Gangaputra, S. Neill, M. Burger, J. Dingledine, V. Gama, R. Sussman, M. Davis, L. Hubbard, M. Budoff, S. Darabian, P. Rezaeian, N. Wong, M. Fox, R. Oudiz, L Kim, R. Detrano, K. Cruickshanks, D. Dalton, K. Bainbridge, J. Lima, D. Bluemke, E. Turkbey, der Geest, C. Liu, A. Malayeri, A. Jain, C. Miao, H. Chahal, R. Jarboe, V. Monnier, D. Sell, C. Strauch, S. Hazen, A. Pratt, W. Tang, J. Brunzell, J. Purnell, R. Natarajan, F. Miao, L. Zhang, Z. Chen, A. Paterson, A. Boright, S. Bull, L. Sun, S. Scherer, T.J. Lyons, A. Jenkins, R. Klein, G. Virella, A. Jaffa, R. Carter, J. Stoner, W.T. Garvey, D. Lackland, M. Brabham, D. McGee, D. Zheng, R.K. Mayfield, J. Maynard, H. Wessells, A Sarma, R. Dunn, S. Holt, J. Hotaling, C. Kim, Q. Clemens, J. Brown, and K. McVary

Subjects
medicine.medical_specialty, endocrine system diseases, 030209 endocrinology & metabolism, Disease, 030204 cardiovascular system & hematology, Lower risk, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Diabetes mellitus, medicine, Diseases of the circulatory (Cardiovascular) system, Coronary Heart Disease, Glycemic, Original Research, free radical, Inflammation, Type 1 diabetes, biology, business.industry, Paraoxonase, medicine.disease, paraoxonase, 3. Good health, RC666-701, Cohort, diabetes mellitus, biology.protein, Cardiology and Cardiovascular Medicine, business, Oxidant Stress, Oxidative stress, F2Isoprostane, Biomarkers
Abstract

Background Hyperglycemia leading to increased oxidative stress is implicated in the increased risk for the development of macrovascular and microvascular complications in patients with type 1 diabetes mellitus. Methods and Results A random subcohort of 349 participants was selected from the DCCT / EDIC (Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications) cohort. This included 320 controls and 29 cardiovascular disease cases that were augmented with 98 additional known cases to yield a case cohort of 447 participants (320 controls, 127 cases). Biosamples from DCCT baseline, year 1, and closeout of DCCT , and 1 to 2 years post‐ DCCT ( EDIC years 1 and 2) were measured for markers of oxidative stress, including plasma myeloperoxidase, paraoxonase activity, urinary F 2α isoprostanes, and its metabolite, 2,3 dinor‐8 iso prostaglandin F 2α . Following adjustment for glycated hemoblobin and weighting the observations inversely proportional to the sampling selection probabilities, higher paraoxonase activity, reflective of antioxidant activity, and 2,3 dinor‐8 iso prostaglandin F 2α , an oxidative marker, were significantly associated with lower risk of cardiovascular disease (−4.5% risk for 10% higher paraoxonase, P iso prostaglandin F 2α , P =0.0092). In contrast, the oxidative markers myeloperoxidase and F 2α isoprostanes were not significantly associated with cardiovascular disease after adjustment for glycated hemoblobin. There were no significant differences between DCCT intensive and conventional treatment groups in the change in all biomarkers across time segments. Conclusions Heightened antioxidant activity (rather than diminished oxidative stress markers) is associated with lower cardiovascular disease risk in type 1 diabetes mellitus, but these biomarkers did not change over time with intensification of glycemic control. Clinical Trial Registration URL : https://www.clinicaltrials.gov . Unique identifiers: NCT 00360815 and NCT 00360893.

Published
2018

14. Insurance coverage for preexisting conditions

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance Law and legislation United States., Health insurance Law and legislation Connecticut., Health care reform Law and legislation United States., Health care reform Law and legislation Connecticut., Health care reform Law and legislation., Health insurance Law and legislation., Connecticut., United States.
Abstract

Summarizes current law regarding coverage for preexisting conditions under a health insurance policy.

Published
2018

15. California law banning the sale of cosmetics tested on animals

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Animal experimentation Law and legislation California., Cosmetics industry Law and legislation California., Cosmetics Toxicity testing California., Cosmétiques Toxicité Californie., Animal experimentation Law and legislation., Cosmetics industry Law and legislation., Cosmetics Toxicity testing., California.
Abstract

Summarizes California's new law that bans the sale of cosmetics tested on animals (S 1249), which the governor signed into law September 28, 2018 and which takes effect January 1, 2020.

Published
2018

16. State laws prohibiting pet leasing

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Pets Law and legislation New York (State), Leases New York (State), Baux New York (État), Leases., Pets Law and legislation., New York (State)
Abstract

Summarizes New York's new law concerning the leasing of dogs and cats (S 7415).

Published
2018

17. OLR backgrounder : state-mandated health insurance benefits

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance Law and legislation Connecticut., Health insurance Law and legislation., Connecticut.
Abstract

Summarizes Connecticut's mandated health insurance benefits. Updates OLR research report 2017-R-0274.

Published
2018

18. Connecticut's health insurance rate review requirements

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance Rates Connecticut., Health insurance Law and legislation Connecticut., Health insurance Law and legislation., Health insurance Rates., Connecticut.
Abstract

Discusses Connecticut's statutory rate review requirements for individual and group health insurance policies. Updates OLR research report 2010-R-0507.

Published
2018

19. 'No pay, no play' auto insurance laws

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Automobile insurance Law and legislation Connecticut., Automobile insurance Law and legislation States. United States, Automobile insurance Law and legislation., Automobile insurance Law and legislation U.S. states., Connecticut., United States.
Abstract

Discusses "no pay, no play" auto insurance law, which states have enacted such a law and whether Connecticut considered adopting one.

Published
2018

20. New Jersey law prohibiting smoking at public parks and beaches

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Smoking Law and legislation New Jersey., Beaches Law and legislation New Jersey., Parks Law and legislation New Jersey., Beaches Law and legislation., Parks Law and legislation., Smoking Law and legislation., New Jersey.
Abstract

Summarizes New Jersey's recently enacted law that prohibits smoking at public parks and beaches.

Published
2018

21. Federal and state individual mandate penalties

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance Law and legislation United States., Health care reform United States., Services de santé Réforme États-Unis., Health care reform., Health insurance Law and legislation., United States.
Abstract

Discusses federal and state-level individual mandate penalties.

Published
2018

22. Service animals and the law

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Service dogs Law and legislation United States., Service dogs Law and legislation Connecticut., People with disabilities Legal status, laws, etc. United States., People with disabilities Legal status, laws, etc. Connecticut., People with disabilities Legal status, laws, etc., Connecticut., United States.
Abstract

Discusses federal and state status of net neutrality issues

Published
2018

23. Federal fine for not having health insurance

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health care reform Law and legislation United States., Health insurance Law and legislation United States., Health care reform Law and legislation., Health insurance Law and legislation., United States.
Abstract

Discusses the federal fine for not having health insurance as required by the Affordable Care Act (ACA) P.L. 111-148, as amended). Also discusses whether any Connecticut residents have paid this federal fine.

Published
2018

24. Acts affecting real estate

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Real property Connecticut., Session laws Connecticut., Biens réels Connecticut., Droit Législation. Connecticut, Real property., Session laws., Connecticut.
Abstract

Discusses new laws (public acts) and a resolution affecting real estate enacted and adopted during the 2018 regular session.

Published
2018

25. Acts affecting animals and agriculture

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Animal welfare Law and legislation Connecticut., Animals Law and legislation Connecticut., Agricultural laws and legislation Connecticut., Session laws Connecticut., Droit Législation. Connecticut, Session laws., Agricultural laws and legislation., Animal welfare Law and legislation., Animals Law and legislation., Connecticut.
Abstract

Discusses new laws (public acts) and a resolution affecting animals and agriculture enacted and adopted during the 2018 regular session.

Published
2018

26. State laws restricting insurers' use of utilization management tools

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance Law and legislation Connecticut., Health insurance Law and legislation., Connecticut.
Abstract

Discusses Connecticut's laws restricting a health insurance company's use of certain utilization management tools, specifically, prior authorization and step therapy.

Published
2018

27. State laws concerning pharmacy benefit managers

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Pharmaceutical services insurance Law and legislation Connecticut., Pharmaceutical services insurance Law and legislation States. United States, Pharmaceutical services insurance Law and legislation., Pharmaceutical services insurance Law and legislation U.S. states., Connecticut., United States.
Abstract

Discusses whether Connecticut or other states regulate pharmacy benefit managers (PBMs).

Published
2018

28. Clostridium difficile suppresses colonic vasoactive intestinal peptide associated with altered motility

Author

A. Nassif, W. E. Longo, R. Sexe, M. Stratton, J. Standeven, A. M. Vernava, and D. L. Kaminski

Subjects
Pathology, RB1-214
Abstract

We investigated whether Clostridium difficile toxin alters colonic tissue levels of vasoactive intestinal peptide (VIP) at the expense of changes in colonic motility in the isolated perfused rabbit left colon. Colonic inflammation was induced by the intracolonic administration of 10−8 M C. difflcile toxin. Strain gauge transducers were sewn onto the serosal surface of the colon to evaluate colonic motility. C. difflcile administration produced histologic changes consistent with epithelial damage. This was associated with an increased production of prostaglandin E2 and thromboxane B2. Tissue levels of VIP but not substance P were significantly reduced. This was associated with an increased number of contractions per minute and an average force of each colonic contraction. These results suggest that tissue levels of VIP are suppressed by C. difflcile and may participate in colonic dysmotility during active inflammation.

Published
1995
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29. OBSERVED PARENTING ASPECTS OF CHILD COMPLIANCE IN CUSTODIAL GRANDFAMILIES

Author

Patricia L. Kaminski, L Portner, Bert Hayslip, and Gregory C. Smith

Subjects
education.field_of_study, Health (social science), Multivariate analysis, media_common.quotation_subject, Multilevel model, Population, Health Professions (miscellaneous), Compliance (psychology), Developmental psychology, Abstracts, Social support, Criticism, Observational study, Praise, Life-span and Life-course Studies, Psychology, education, media_common
Abstract

For a myriad of reasons, custodial grandchildren are generally at greater risk of behavioral and emotional difficulties, such as hyperactivity-inattention (HI) (Smith & Palmieri, 2007). Custodial grandmothers (N = 170) completed self-report measures assessing child HI, expressive social support, and custodial grandmother-grandchild compliance variables. Grandmothers and their grandchildren aged 4 through 12 also completed an observational task that captured their interactions. A multivariate analysis of covariance tested differences between high and low hyperactivity-inattention on observed parenting variables while controlling for child age. As there were significant differences between child age and observed parenting variables, a subsequent hierarchical regression model revealed that when controlling for age, child hyperactivity-inattention did not moderate the relationship between commands given by a custodial grandmother and child compliance, but instead revealed that direct commands from the grandmother predicted child compliance. A second hierarchical regression model suggested that encouragement and praise (versus criticism and discouragement) from a grandmother functioned differently across types of commands given, when controlling for child age. It appeared that when grandmothers gave indirect commands more frequently, encouragement and praise instead of criticism was associated with greater compliance. In dyads with frequent direct commands given, compliance was high. However children in dyads who scored high in direct commands accompanied by criticism and discouragement were most likely to comply. This study adds to the knowledge base regarding the nature of grandmother caregiver-grandchild interaction by providing insight into the child-rearing challenges and strengths faced by grandmothers in this unique population.

Published
2018
Full Text
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30. Rational Design of Network Properties in Guest–Host Assembled and Shear-Thinning Hyaluronic Acid Hydrogels

Author

Jason A. Burdick, Christopher B. Rodell, and Adam L Kaminski

Subjects
Polymers and Plastics, Adamantane, Bioengineering, Beta-Cyclodextrins, macromolecular substances, Article, Biomaterials, chemistry.chemical_compound, Polymer chemistry, Hyaluronic acid, Materials Chemistry, Molecule, Hyaluronic Acid, chemistry.chemical_classification, Molecular Structure, Biomolecule, beta-Cyclodextrins, technology, industry, and agriculture, Rational design, Hydrogels, Macromonomer, chemistry, Chemical engineering, Self-healing hydrogels, Rheology
Abstract

Shear-thinning hydrogels afford direct injection or catheter delivery to tissues without potential premature gel formation and delivery failure or the use of triggers such as chemical initiators or heat. However, many shear-thinning hydrogels require long reassembly times or exhibit rapid erosion. We developed a shear-thinning hyaluronic acid (HA) hydrogel based on the guest-host interactions of adamantane modified HA (guest macromer, Ad-HA) and β-cyclodextrin modified HA (host macromer, CD-HA). The ability of the guest and host molecules to interact with their counterpart following conjugation to HA was confirmed by (1)H NMR spectroscopy and was similar to that of the native complex. Mixing of Ad-HA and CD-HA resulted in rapid formation of a hydrogel composed of guest-host bonds. The hydrogel physical properties, including mechanics and flow characteristics, were dependent on cross-link density and network structure, which were controlled through macromer concentration, the extent of guest macromer modification, and the molar ratio of guest and host functional groups. The guest-host assembly mechanism permitted both shear-thinning behavior for ease of injection and near-instantaneous reassembly for material retention at the target sight. The hydrogel erosion and release of a model biomolecule were also dependent on design parameters and were sustained for over 60 days. These hydrogels show potential as a minimally invasive injectable hydrogel for biomedical applications.

Published
2013
Full Text
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31. Town ordinances banning frackng waste

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Hazardous wastes Law and legislation Connecticut., Gas wells Environmental aspects Law and legislation Connecticut., Hydraulic fracturing Environmental aspects Law and legislation Connecticut., Hazardous wastes Law and legislation., Connecticut.
Abstract

Discusses Connecticut towns that have adopted ordinances banning frackng waste.

Published
2017

32. Massachusetts contraceptive coverage requirement

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Birth control Law and legislation Massachusetts., Contraception Law and legislation Massachusetts., Health insurance Law and legislation Massachusetts., Birth control Law and legislation., Health insurance Law and legislation., Massachusetts.
Abstract

Summarizes Massachusetts' recently enacted law requiring insurance policies to cover contraception and Connecticut's sSB 586 (sections 7 and 8) from 2017.

Published
2017

33. Continuity of care requirements for Connecticut insurance coverage

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Continuum of care Law and legislation Connecticut., Health insurance Law and legislation Connecticut., Health insurance Law and legislation., Connecticut.
Abstract

Summarizes Connecticut's continuity of care requirements for insurance coverage and discusses when they were enacted.

Published
2017

34. Prosthetic parity bills considered in Connecticut

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Prosthesis Law and legislation Connecticut., Health insurance Law and legislation Connecticut., Bills, Legislative Connecticut., Projets de loi Connecticut., Bills, Legislative., Health insurance Law and legislation., Connecticut.
Abstract

Summarizes the bills considered by the Insurance and Real Estate Committee in 2009 and 2011 concerning prosthetic parity and the history of each.

Published
2017

35. Drought stages and action steps in Connecticut

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Water conservation Law and legislation Connecticut., Droughts Law and legislation Connecticut., Water conservation Law and legislation., Connecticut.
Abstract

Discusses whether state law or regulation requires businesses or residents to reduce water use during a drought.

Published
2017

36. Penalties for driving without auto insurance

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Automobile insurance Law and legislation Connecticut., Automobile insurance Law and legislation., Connecticut.
Abstract

Discusses penalties for driving an uninsured vehicle in Connecticut. Updates and replaces OLR research report 2016-R-0037.

Published
2017

37. Transporting fracking waste through Connecticut

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Hydraulic fracturing Law and legislation Connecticut., Hazardous wastes Transportation Law and legislation Connecticut., Interstate commerce Law and legislation United States., Constitutional law United States., Constitutional law., Hazardous wastes Transportation Law and legislation., Hydraulic fracturing Law and legislation., Interstate commerce Law and legislation., Connecticut., United States.
Abstract

Discusses whether the legislature could pass a law prohibiting the transport of fracking waste through Connecticut.

Published
2017

38. OLR backgrounder : state-mandated health insurance benefits

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance Law and legislation Connecticut., Health insurance Law and legislation., Connecticut.
Abstract

Discusses Connecticut's mandated health insurance benefits. Updates OLR research report 2016-R-0254.

Published
2017

39. Misrepresentation of a service animal

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Animals as aids for people with disabilities Law and legislation Massachusetts., Animals as aids for people with disabilities Law and legislation Connecticut., Connecticut., Massachusetts.
Abstract

Discusses proposed Massachusetts bill about misrepresenting a service animal. Discusses whether Connecticut or any other state has passed similar legislation.

Published
2017

40. Agritourism definition

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Agritourism Law and legislation States. United States, United States.
Abstract

Discusses how other states' statutes define "agritourism."

Published
2017

41. Backgrounder : Connecticut Unfair Insurance Practices Act (CUIPA)

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Insurance law Connecticut., Insurance State supervision Connecticut., Assurance Contrôle de l'État Connecticut., Insurance law., Insurance State supervision., Connecticut.
Abstract

Discusses the Connecticut Unfair Insurance Practices Act, including violations, enforcement, methods, and penalties.

Published
2017

42. CGS 38a-518f--insurance coverage for certain prescription drugs removed from a formulary

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Pharmaceutical services insurance Law and legislation Connecticut., Health insurance Law and legislation Connecticut., Drugs Prescribing Law and legislation Connecticut., Drugs Prescribing Law and legislation., Health insurance Law and legislation., Pharmaceutical services insurance Law and legislation., Connecticut.
Abstract

Discusses legislative history of CGS 38a-518f and addresses whether state law requires health insurers and HMOs to notify enrollees of prescription drug coverage changes.

Published
2017

43. Traveling zoos

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Animal welfare Law and legislation Connecticut., Livestock exhibitions Law and legislation Connecticut., Zoos Law and legislation Connecticut., Animal welfare Law and legislation., Livestock exhibitions Law and legislation., Connecticut.
Abstract

Discusses whether the state licenses or regulates traveling zoos.

Published
2017

44. COBRA coverage versus special enrollment in Access Health CT plan

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Health insurance continuation coverage Law and legislation United States., Health insurance continuation coverage Law and legislation., United States.
Abstract

Discusses whether a person aged 62 to 65 who has experienced a qualifying life event causing that person to lose job-based health insurance coverage may elect coverage under the federal Consolidated Omnibus Budget Reconciliation Act or whether the federal Affordable Care Act requires that person to obtain individual coverage through the state's health insurance exchange.

Published
2017

45. Calculating insurance settlements on totaled vehicles

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Automobile insurance claims Law and legislation Connecticut., Automobile insurance Law and legislation Connecticut., Automobiles Collision damage Law and legislation Connecticut., Automobile insurance Law and legislation., Connecticut.
Abstract

Discusses whether state law mandates how auto insurers must calculate the claim settlement amount for a totaled motor vehicle. Replaces OLR research report 2004-R-0674.

Published
2017

46. Connecticut's PA 490 Program

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Property tax relief Connecticut., Open spaces Law and legislation Connecticut., Land use, Rural Law and legislation Connecticut., Land use, Rural Law and legislation., Open spaces Law and legislation., Property tax relief., Connecticut.
Abstract

Discusses Connecticut's PA 490 Program, enacted in 1963.

Published
2017

47. Acts affecting real estate

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Real property Connecticut., Session laws Connecticut., Biens réels Connecticut., Droit Législation. Connecticut, Real property., Session laws., Connecticut.
Abstract

Discusses new laws (public acts) affecting real estate enacted during the enacted during the 2017 regular session.

Published
2017

48. Acts affecting animals and agriculture

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Animal welfare Law and legislation Connecticut., Animals Law and legislation Connecticut., Agricultural laws and legislation Connecticut., Agricultural laws and legislation., Animal welfare Law and legislation., Animals Law and legislation., Connecticut.
Abstract

Discusses new laws (public acts) affecting animals and agriculture enacted during the 2017 regular session.

Published
2017

49. States that ban smoking in state parks

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Smoking Law and legislation States. United States, Parks Law and legislation States. United States, Parks Law and legislation U.S. states., Smoking Law and legislation U.S. states., United States.
Abstract

Discusses whether any states ban smoking in state parks.

Published
2017

50. Auto liability insurance requirements in other states

Author

Leduc, Janet L. Kaminski and Leduc, Janet L. Kaminski

Subjects
Automobile insurance Law and legislation States. United States, Uninsured motorist insurance Law and legislation States. United States, Underinsured motorist insurance Law and legislation States. United States, Automobile insurance Law and legislation U.S. states., Uninsured motorist insurance Law and legislation U.S. states., United States.
Abstract

Discusses states that require people to purchase auto liability insurance, uninsured motorist coverage, and underinsured motorist coverage. Updates and replaces OLR research report 2013-R-0258.

Published
2017

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