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1. Association Between Lifestyle and Systemic Arterial Hypertension in Young Adults: A National, Survey-Based, Cross-Sectional Study

Author

Bruno, R, Pucci, G, Rosticci, M, Guarino, L, Guglielmo, C, Rosei, C, Monticone, S, Giavarini, A, Lonati, C, Torlasco, C, Fedecostante, M, Manzi, M, Pezzutto, F, Di Pilla, M, Artom, N, Battistoni, A, Pignatelli, G, Sanga, V, Pengo, M, Bruno RM, Pucci G, Rosticci M, Guarino L, Guglielmo C, Rosei CA, Monticone S, Giavarini A, Lonati C, Torlasco C, Fedecostante M, Manzi MV, Pezzutto F, Di Pilla M, Artom N, Battistoni A, Pignatelli G, Sanga V, Pengo M, Bruno, R, Pucci, G, Rosticci, M, Guarino, L, Guglielmo, C, Rosei, C, Monticone, S, Giavarini, A, Lonati, C, Torlasco, C, Fedecostante, M, Manzi, M, Pezzutto, F, Di Pilla, M, Artom, N, Battistoni, A, Pignatelli, G, Sanga, V, Pengo, M, Bruno RM, Pucci G, Rosticci M, Guarino L, Guglielmo C, Rosei CA, Monticone S, Giavarini A, Lonati C, Torlasco C, Fedecostante M, Manzi MV, Pezzutto F, Di Pilla M, Artom N, Battistoni A, Pignatelli G, Sanga V, and Pengo M

Abstract

Introduction: The prevalence of systemic arterial hypertension in young adults is increasing worldwide in association with modifiable risk factors. Aim: To assess the prevalence of high blood pressure (BP) in young adults participating to a screening campaign during the World Hypertension Day (17/05/2014), and to determine the possible association with lifestyle factors. Methods: 493 individuals aged 18–35 years were selected in 13 Italian cities. All participants underwent BP measurement together with the administration of a questionnaire exploring: medical and drug history; traditional cardiovascular risk factors and diseases; dietary pattern; salt intake; sleep habits; mood disorders. Results: High BP (≥140/90 mmHg) was found in 54 individuals, with a prevalence of 11 % and awareness of 28 %. Those with high BP values were more frequently men, reported a higher BMI and a greater use of corticosteroids and non-steroidal anti-inflammatory drugs, and had a lower anxiety score. Concerning dietary habits, they were more likely to eat cheese/cold cuts ≥3 times/week, to have their meals out ≥1/day and to eat in fast foods ≥1/week. In the multiple logistic regression analysis, male sex [OR 3.19, 95 % CI (1.33–7.63)], BMI [OR 1.14 95 % CI (1.04–1.25)], eating in fast foods [OR 3.10 95 % CI (1.21–7.95)], and anxiety [OR 0.85 95 % CI (0.75–0.97)], were independently associated with high BP. Conclusions: High BP values were found in 11 % young adults. Male sex, adiposity and alimentary habits were the main determinants of high BP values, indicating that young men are a suitable target for healthy lifestyle interventions.

Published
2016

2. Association between lifestyle and systemic arterial hypertension in young adults. a national, survey-based, cross-sectional study

Author

Claudia Agabiti Rosei, Martino F. Pengo, Nathan Artom, Silvia Monticone, Laura Guarino, Maria Virginia Manzi, Giulia Pignatelli, Marina Di Pilla, Chiara Lonati, Viola Sanga, Allegra Battistoni, Alessandra Giavarini, Giacomo Pucci, Rosa Maria Bruno, Martina Rosticci, Francesca Pezzutto, Camilla Torlasco, Massimiliano Fedecostante, Chiara Guglielmo, Bruno, R, Pucci, G, Rosticci, M, Guarino, L, Guglielmo, C, Rosei, C, Monticone, S, Giavarini, A, Lonati, C, Torlasco, C, Fedecostante, M, Manzi, M, Pezzutto, F, Di Pilla, M, Artom, N, Battistoni, A, Pignatelli, G, Sanga, V, Pengo, M, Bruno, Rosa Maria, Pucci, Giacomo, Rosticci, Martina, Guarino, Laura, Guglielmo, Chiara, Agabiti Rosei, Claudia, Monticone, Silvia, Giavarini, Alessandra, Lonati, Chiara, Torlasco, Camilla, Fedecostante, Massimiliano, Manzi, Maria Virginia, Pezzutto, Francesca, Di Pilla, Marina, Artom, Nathan, Battistoni, Allegra, Pignatelli, Giulia, Sanga, Viola, and Pengo, Martino Francesco

Subjects
Male, Pediatrics, age distribution, Cross-sectional study, Sex Factor, 030204 cardiovascular system & hematology, Adrenal Cortex Hormone, 0302 clinical medicine, Risk Factors, Blood pressure, Dietary habits, Hypertension, Lifestyle, Young adults, Odds Ratio, Prevalence, Medicine, Age Factor, 030212 general & internal medicine, Young adult, Multivariate Analysi, adiposity, adult, Anti-Inflammatory Agents, Non-Steroidal, blood pressure, Health Survey, anxiety, Italy, Anxiety, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, Human, young adults, medicine.medical_specialty, lifestyle, age factors, hypertension, Logistic Model, Fast Food, body mass index, adrenal cortex hormones, Dietary habit, anti-inflammatory agents, non-steroidal, 03 medical and health sciences, Sex Factors, Internal Medicine, Humans, Arterial Pressure, Obesity, Sex Distribution, Salt intake, Life Style, dietary habits, adolescent, anti-inflammatory agents, non-steroidal, Adiposity, Adolescent, Adrenal Cortex Hormones, Adult, Age Distribution, Age Factors, Body Mass Index, Chi-Square Distribution, Cross-Sectional Studies, Fast Foods, Feeding Behavior, Health Surveys, Logistic Models, Multivariate Analysis, Risk Reduction Behavior, Young Adult, Cross-Sectional Studie, business.industry, Risk Factor, Odds ratio, medicine.disease, business, Body mass index, Demography
Abstract

Introduction: The prevalence of systemic arterial hypertension in young adults is increasing worldwide in association with modifiable risk factors. Aim: To assess the prevalence of high blood pressure (BP) in young adults participating to a screening campaign during the World Hypertension Day (17/05/2014), and to determine the possible association with lifestyle factors. Methods: 493 individuals aged 18–35 years were selected in 13 Italian cities. All participants underwent BP measurement together with the administration of a questionnaire exploring: medical and drug history; traditional cardiovascular risk factors and diseases; dietary pattern; salt intake; sleep habits; mood disorders. Results: High BP (≥140/90 mmHg) was found in 54 individuals, with a prevalence of 11 % and awareness of 28 %. Those with high BP values were more frequently men, reported a higher BMI and a greater use of corticosteroids and non-steroidal anti-inflammatory drugs, and had a lower anxiety score. Concerning dietary habits, they were more likely to eat cheese/cold cuts ≥3 times/week, to have their meals out ≥1/day and to eat in fast foods ≥1/week. In the multiple logistic regression analysis, male sex [OR 3.19, 95 % CI (1.33–7.63)], BMI [OR 1.14 95 % CI (1.04–1.25)], eating in fast foods [OR 3.10 95 % CI (1.21–7.95)], and anxiety [OR 0.85 95 % CI (0.75–0.97)], were independently associated with high BP. Conclusions: High BP values were found in 11 % young adults. Male sex, adiposity and alimentary habits were the main determinants of high BP values, indicating that young men are a suitable target for healthy lifestyle interventions.

Published
2016

3. Early renal failure as a cardiovascular disease: Focus on lipoprotein(a) and prothrombotic state.

Author

Catena C, Colussi G, Nait F, Pezzutto F, Martinis F, and Sechi LA

Abstract

Patients with renal failure are at increased risk of cardiovascular events even at the earliest stages of disease. In addition to many classic cardiovascular risk factors, many conditions that are commonly identified as emerging risk factors might contribute to occurrence of cardiovascular disease. Changes in circulating levels of many of these emerging risk factors have been demonstrated in patients with early stages of renal failure caused by different types of renal disease and have been associated with detection of cardiovascular complications. However, for most of these factors evidence of benefits of correction on cardiovascular outcome is missing. In this article, we comment on the role of lipoprotein(a) and prothrombotic factors as potential contributors to cardiovascular events in patients with early renal failure.

Published
2015
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4. Aldosterone and the heart: still an unresolved issue?

Author

Catena C, Colussi G, Nait F, Martinis F, Pezzutto F, and Sechi LA

Abstract

Receptors for mineralocorticoid hormones are expressed in myocardial cells and evidence obtained in animal studies suggests that activation of these receptors causes cardiac damage independent from blood pressure levels. In the last years, many of the issues related to the effects of aldosterone on the heart have received convincing answers and clinical investigation has focused on a variety of conditions including systolic and diastolic heart failure, arrhythmia, primary hypertension, and primary aldosteronism. Some issues, however, await clarification in order to obtain better understanding of what could be the role of aldosterone blockade in prevention and treatment of cardiovascular diseases. In this article, we overview the most recent findings of animal studies that have examined the contribution of aldosterone to cardiac function and clinical studies that have investigated the influence of aldosterone on left ventricular structure and function in the setting of primary hypertension and primary aldosteronism.

Published
2014
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