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Structures composed of aviation aluminium alloys, characterized by their limited rigidity and thin-walled configurations, frequently exhibit deformation after processing. This paper presents an investigation into T-shaped components fabricated from pre-stretched 7075-T7451 aviation aluminium alloy sheets, examining the effects of residual stress and the geometrical parameters of T-shaped components on their deformational behavior. A semi-analytical model, developed to elucidate the bending deformation of T-shaped components subjected to residual stress, was validated through finite element analysis and empirical cutting experiments. The experimental results revealed that the bending deformation deflection of the T-shaped specimen was 0.920 mm, deviating by a mere 0.011 mm from the prediction provided by the semi-analytical model, resulting in an inconsequential error margin of 1.2%. This concordance underscores the precision and accuracy of the semi-analytical model specifically designed for T-shaped components. Moreover, the model's simplicity and ease of application make it an effective tool for predicting the bending deformation of thin-walled T-shaped components under a range of residual stresses and dimensional variations, thereby demonstrating its significant utility in engineering applications. [ABSTRACT FROM AUTHOR]

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a critical and life-threatening illness that causes severe dyspnea, and respiratory distress and is often caused by a variety of direct or indirect factors that damage the alveolar epithelium and capillary endothelial cells, leading to inflammation factors and macrophage infiltration. Macrophages play a crucial role in the progression of ALI/ARDS, exhibiting different polarized forms at different stages of the disease that control the disease outcome. MicroRNAs (miRNA) are conserved, endogenous, short non-coding RNAs composed of 18-25 nucleotides that serve as potential markers for many diseases and are involved in various biological processes, including cell proliferation, apoptosis, and differentiation. In this review, we provide a brief overview of miRNA expression in ALI/ARDS and summarize recent research on the mechanism and pathways by which miRNAs respond to macrophage polarization, inflammation, and apoptosis. The characteristics of each pathway are also summarized to provide a comprehensive understanding of the role of miRNAs in regulating macrophage polarization during ALI/ARDS.